
Recent Publications
Iron regulatory protein-1 and -2: transcriptome-wide definition of binding mRNAs and shaping of the cellular proteome by IRPs.
Sanchez, M., B. Galy, B. Schwanhaeusser, J. Blake, T. Bähr-Ivacevic, V. Benes, M. Selbach, M.U. Muckenthaler and M.W. Hentze.
Blood 118: e168-79, Nov 2011
The liver-specific microRNA miR-122 controls systemic iron homeostasis in mice.
Castoldi M, Vujić Spasić M, Altamura S, Elmén J, Lindow M, Kiss J, Stolte J, Sparla R, D'Alessandro LA, Klingmüller U, Fleming RE, Longerich T, Gröne HJ, Benes V, Kauppinen S, Hentze MW, Muckenthaler MU.
J Clin Invest. 2011 Apr 1;121(4):1386-96
SnapShot: protein-protein interaction networks.
Seebacher J. and Gavin A.C.
Cell 2011 March 18;144, 1000
p38 MAPK controls prothrombin expression by regulated RNA 3' end processing.
Danckwardt S, Gantzert AS, Macher-Goeppinger S, Probst HC, Gentzel M, Wilm M, Gröne HJ, Schirmacher P, Hentze MW, Kulozik AE.
Mol Cell. 2011 Feb 4;41(3):298-310.
Two to tango: regulation of mammalian iron metabolism
Hentze, M.W., M.U. Muckenthaler, B. Galy and C. Camaschella.
Cell 142, 24-38, 2010
Airway surface liquid volume regulation determines different airway phenotypes in liddle's compared to {beta}ENAC-overexpressing mice
Mall MA, Button B, Johannesson B, Zhou Z, Livraghi A, Caldwell RA, Schubert SC, Schultz C, O'Neal WK, Pradervand S, Hummler E, Rossier BC, Grubb BR, Boucher RC.
J Biol Chem. 2010 Aug 27;285(35):26945-55. Epub 2010 Jun 21
SelTarbase, a database of human mononucleotide-microsatellite mutations and their potential impact to tumorigenesis and immunology
Woerner SM, Yuan YP, Benner A, Korff S, von Knebel Doeberitz M, Bork P
Nucleic Acids Res. 2010 Jan; 38 (Database issue)
SMAD7 controls iron metabolism as a potent inhibitor of hepcidin expression
Mleczko-Sanecka, K., G. Casanovas, A. Ragab, K. Breitkopf, M. Boutros, S. Dooley, M.W. Hentze and M.U. Muckenthaler.
Blood. 115, 2657-2665, 2010
Membrane-bound FRET probe visualizes MMP12 activity in pulmonary inflammation
Cobos-Correa A, Trojanek JB, Diemer S, Mall MA, Schultz C.
Nat Chem Biol. 2009 Sep;5(9):628-30. Epub 2009 Aug 2.
Disassembly of exon junction complexes by PYM
Gehring N.H., S. Lamprinaki, A.E. Kulozik, M.W. Hentze.
Cell. 2009 May 1;137(3):536-48.
DetecTiff: A novel image analysis routine for high content screening microscopy
Gilbert D, Meinhof T, Pepperkok R, Runz H.,
J. Biomol Screen. 2009 Sept;14(8):944-55. Epub 2009 Jul 29
Identification of cholesterol-regulating genes by targeted RNAi-screening
Bartz F, Kern L, Erz D, Zhu M, Gilbert D, Meinhof T, Wirkner U, Erfle H, Muckenthaler M, Pepperkok R, Runz H,
Cell Metab. 2009 Jul;10(1):63-75
The hierarchy of exon-junction complex assembly by the spliceosome explains key features of mammalian nonsense-mediated mRNA decay
Gehring N.H., S. Lamprinaki, M.W. Hentze, A.E. Kulozik.
PLoS Biol. 2009 May 26;7(5):e1000120. Epub 2009 May 26.
Bone morphogenetic protein (BMP)-responsive elements located in the proximal and distal hepcidin promoter are critical for its response to HJV/BMP/SMAD
Casanovas G, Mleczko-Sanecka K, Altamura S, Hentze MW, Muckenthaler MU.
J Mol Med. 2009 May;87(5):471-80. Epub 2009 Feb 20
High frequency of LMAN1 abnormalities in colorectal tumors with microsatellite instability
Roeckel N, Woerner SM, Kloor M, Yuan YP, Patsos G, Gromes R, Kopitz J, Gebert, J.
Cancer Res 2009; 69(1):292-9.
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