Gastroenterologie, Infektionskrankheiten, Vergiftungen

 

The Füllekrug Lab

 

Overview

Group leader

Research team

Projects

Publications

 

 


 

Margarete Poppelreuther (Digel), PhD

Margarete is focused on the the hormonal regulation of lipid metabolism, especially the mechanism of insulin resistance. Besides that, she takes care of almost everything in the lab and has a hand in all other projects.

 

Poppelreuther et al., 2012

Digel et al., 2011

 

 

 

  

 


Fadil Minden, MD student

Fadil is interested in the function of the acyl-CoA synthetase 3 on lipid droplets.


Peter Hoffmann, MD

Peter is a resident physician. He started to characterize the lipid metabolism of hepatocellular carcinoma.




Former Group Members


Sarah Staudacher, MD student

Sarah prepared recombinant FATP4 and ACSL3, allowing the quantification of these enzymes in tissues and subcellular fractions by Western blotting.


Friedrich Ehehalt, MD student 

Friedrich established the analysis of the mammalian long chain acyl-CoA synthetases by quantitative PCR. 


Eva-Maria Küch, PhD

Eva followed the idea that acyl-CoA synthetases may channel fatty acids towards specific metabolic pathways. She defended her PhD on February 28th, 2012.

Congratulations !


Tianzuo Zhan received his MD in 2011 and is now a resident physician at the University Hospital Mannheim.


Chen Du depleted ACSL3 from A431 cells by RNA interference and found reduced cellular uptake of fatty acids. Chen works now on adipogenesis at the NIH.


Regina Großmann did her MD thesis on the localization of ACSL4 and ACSL3.


Berenice Rudolph did pioneering work on the dynamic localization of ACSL3 during her MD thesis.



 

We are closely collaborating with the Ehehalt group


 

Robert Ehehalt, MD

Robert is the Managing Senior Physician of our Department. His research interests are the pathogenesis of liver steatosis and the mucus barrier of the chronically inflamed intestine.  

 

Roberts Homepage

 

 

 


 

Hannah Schneider, MSc

Hannah is a PhD student. She looks at membrane proteins facilitating fatty acid transport in polarized cells. 

 

 

 

 

 

 

 

 



 

Annika Braun, MD

Annika is Chief Resident Physician in our Department. She is interested in the lipid composition of the intestinal mucosa. In collaboration with Wolf Dieter Lehmann at the DKFZ she applies nanoESI-MS/MS for the quantification of phospholipids.

 

 

 


Inga Buchholz



 

Open positions

I am looking for a student of biochemistry (biology, chemistry) to join the lab for an experimental master thesis on fatty acid metabolism.  

All research is relevant for the molecular mechanism of pathogenic processes. Our model system are mammalian cells grown in tissue culture. The technical approaches comprise molecular biology (cloning, mutagenesis, RNA interference), microscopy (immunofluorescence, GFP, confocal analysis), and biochemistry (uptake assays, subcellular fractionation). 

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