HYPOthermia 24/7 - Research Group
Temperature Management in Cerebrovascular Disease
Dr. Sven Poli, MD (Head of Group)
PD Dr. Erik Popp, MD (Associate Consultant in Anesthesiology)
Completed trials:
- RhinoChill device for induction of cooling in stroke patients (case series, n=10)
- Sovika cooling helmet for induction of cooling in stroke patients (case series, n=11)
- iCOOL 1 (induction of COOLing 1): A randomized trial comparing Cold Infusions vs. RhinoChill for rapid cooling of stroke patients (n=20, NCT01573117)
- iCOOL 3 (induction of COOLing 3): A randomized trial comparing Cold Infusions vs. EMCOOLS Brain.Pads for rapid cooling of stroke patients (n=20, NCT01584180)
Active trials:
- Prehospital stroke treatment (retrospective analysis 2007-2010)
- HAIS-SE (Hypothermia in Acute Ischemic Stroke - Surface versus Endovascular cooling): A randomized controlled trial comparing endovascular and surface cooling in awake stroke patients, IIT, financial support by ZOLL (n=60)
- iCOOL 2 (induction of COOLing 2): A randomized trial comparing Cold Infusions vs. EMCOOLS Flex.Pads for rapid cooling of stroke patients (n=20, NCT01584167)
- PreCOOL 1 (Prehospital COOLing 1): A randomized controlled trial evaluating Cold Infusions for prehospital induction of cooling in awake stroke patients (n=40)
International hypothermia trials:
- CINCH (PI Poli)
- DEPTH-SOS (PI Bösel, on hold)
- EuroHyp-1 (PI Poli, start 2012)
- ICTuS2/3 (PI Poli, on hold)
Support by:
BeneChill, Cincinnati Sub-Zero, Covidien, EMCOOLS, HVM Medical, Raumedic, ZOLL
Memberships:
European Stroke Research Network of Hypothermia
Cooperations:
AG Multimodales Monitoring (AG Diedler/Sykora)
AG Critical Care of Stroke (AG Bösel)
Contact:
Department of Neurology - University of Heidelberg
INF 400 | 69120 Heidelberg | Germany
Tel: 0049 6221 56-3HYPO (-34976)
Fax: 0049 6221 56-5461





