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Translational Lung Research Center Heidelberg

Chronic Obstructive Pulmonary Disease

According to the World Health Organization (WHO), chronic obstructive pulmonary disease (COPD) is the fourth most common cause of death worldwide. It is estimated that 10 to 12% of adults above 40 years of age in Germany suffer from COPD. The causes for COPD include environmental, as well as genetic factors and in developed countries by far the biggest risk factor for developing COPD is past or present smoking.

COPD is a condition in which the airways in the lungs become damaged, making it increasingly difficult for air to move in and out. Current treatment options can help slow the progression of the condition and reduce the symptoms, but to date, there are no effective treatments to hold or reverse the disease.

The long-term goal of the COPD research at the DZL is the translation of novel mechanism-based therapeutic concepts into effective therapies for COPD patients. Research at the TLRC focuses on

  • cellular and molecular mechanisms of inflammation in COPD,
  • identification of new targets for therapy,
  • novel surgical approaches to improve disease outcome and
  • advancement of imaging technologies for improved diagnosis, monitoring of disease progression and response to targeted therapies.



Faculty & Research Program

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