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Translational Lung Research Center Heidelberg

Cystic Fibrosis

Cystic fibrosis (CF) is the most common genetically determined, early onset and still lethal form of chronic obstructive lung disease. CF affects approximately one in 2500 newborns in Germany. With improvements in symptomatic therapies and standardized CF medical care, the median survival age of CF patients in Germany has risen to approximately 40 years. However, despite recent breakthroughs in disease-modifying therapies for a small subgroup of patients with specific CF genotypes, there are currently no therapies available to the majority of patients that target CF lung disease at its root.

 

The overall aim of the DZL CF research program is to advance the current understanding of the pathogenesis of CF lung disease and to use this knowledge to improve CF diagnostics, develop more sensitive tools for monitoring of disease activity, and develop novel strategies for the effective prevention and therapy of CF lung disease.

 

Research Groups

this section is under development

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