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Pharmacoepidemiology

 

The division Pharmacoepidemiology investigates the use of drugs and (adverse) effects of drug therapy in populations to improve drug regimens with respect to effectiveness and safety. The Pharmacoepidemiology research group is committed to establish this relatively new scientific discipline at the University of Heidelberg as an integral part of the Department of Clinical Pharmacology and Pharmacoepidemiology. Conceptually, the identification of patient characteristics related to drug administration is used to enhance drug effectiveness and patient safety for the individual (i.e. towards an individualized drug therapy and personalized medicine) and populations.

 

 

Staff

Head:

Dr. sc. hum. Andreas Meid

Scientific Staff:Carmen Ruff
ERASMUS-student:Ludmila Koukalova

 

Services

  • Design, conduct, and analysis of drug administration and safety studies in patient record databases
  • Preparation of study protocols
  • Conduct and analysis of field studies
  • Population-based cohort studies and interventional studies in primary care, analyses of secondary data potentially followed by interventions in cooperation with the health insurance statutory
  • Statistical and epidemiological consulting

Research Activities

Using medication data obtained from large population-based epidemiological studies or prescription claims databases, the research group investigates risk constellations in drug treatment and derives strategies for their prevention or management. The resulting findings can be used to  avoid or manage situations with increased risks. Current research activities focus on drug prescribing and drug administration in ambulatory patients. In this respect, particular attention is given to special populations (e.g., older people, frail patients, patients with poly-pharmacy, among others). A major aim is to identify risk factors threatening the safety and effectiveness of drug treatments. In addition, the section develops interventional strategies to detect problems in the drug administration of older outpatients and to improve their pharmacological treatments substantially.

 

Cooperations

    • Abteilung Klinische Epidemiologie und Alternsforschung, Deutsches Krebsforschungszentrum (DKFZ), Heidelberg
    • Elsevier Health Analytics, Berlin
    • Wissenschaftliches Institut der AOK (WIdO), Berlin
    • Universitätsklinikum Hamburg-Eppendorf, Institut für Medizinische Soziologie, Sozialmedizin und Gesundheitsökonomie (IMSG)
    • Mathematisches Institut der Universität München (LMU), Arbeitsgruppe Stochastik und Finanzmathematik
    • Abteilung Allgemeinmedizin und Versorgungsforschung, Universitätsklinikum Heidelberg
    • AQUA-Institut, Göttingen 
    • Institut für Allgemeinmedizin, Johann Wolfgang Goethe-Universität, Frankfurt a.M.
    • Stiftung Institut für Herzinfarktforschung, Ludwigshafen a.Rh.
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