Kliniken &… Kliniken Zentrum für Innere… Innere Medizin III:… Forschung Arbeitsgruppen Grundlagenforschung … Cardiac Remodeling and… Publications

Publications

miR-222 inhibits pathological cardiac hypertrophyand heart failure. Liu X, Li H, Hastings MH, Xiao C, Damilano F, Platt C, Lerchenmüller C, Zhu H, Wei XP, Yeri A, Most P, Rosenzweig A. Cardiovasc Res. 2023 Dec 12:cvad184. doi: 10.1093/cvr/cvad184. Online ahead of print. PMID: 38084908

Intrinsic and Extrinsic Contributors to the Cardiac Benefits of Exercise Hastings MH, Castro C, Freeman R, Kadir AA, Lerchenmüller C, Li H, Rhee J, Roh JD, Roh K, Singh A, Chao Wu, Peng Xia, Qiulian Zhou, Junjie Xiao, Anthony Rosenzweig. JACC: Basic to Translational Science 2023. doi: 10.1016/j.jacbts.2023.07.011.

Gender disparities in altmetric attention scores for cardiovascular research - PubMed (nih.gov) Lerchenmueller MJ, Schmallenbach L, Bley M, Lerchenmüller C. Commun Biol. 2023 Jul 17;6(1):741. doi: 10.1038/s42003-023-05058-9. PMID: 37460580; PMCID: PMC10352379.  

Moving toward gender equity in the cardiology and cardiovascular research workforce in Germany: a report from the German Cardiac Society - PubMed (nih.gov) Lerchenmüller C, Zelarayan L, Streckfuss-Bömeke K, Gimenez MR, Schnabel R, Hashemi D, Baldus S, Rudolph TK, Morbach C. Eur Heart J Open. 2023 Mar 29;3(2):oead034. doi: 10.1093/ehjopen/oead034. PMID: 37090057; PMCID: PMC10114529.

Restoration of Cardiomyogenesis in Aged Mouse Hearts by Voluntary Exercise - PubMed (nih.gov) Lerchenmüller C, Vujic A, Mittag S, Wang A, Rabolli CP, Heß C, Betge F, Rangrez AY, Chaklader M, Guillermier C, Gyngard F, Roh JD, Li H, Steinhauser ML, Frey N, Rothermel B, Dieterich C, Rosenzweig A, Lee RT. Restoration of Cardiomyogenesis in Aged Mouse Hearts by Voluntary Exercise. Circulation. 2022 Aug 2;146(5):412-426. doi: 10.1161/CIRCULATIONAHA.121.057276. Epub 2022 Jul 6. PMID: 35862076; PMCID: PMC9357140.
Press release: https://www.spiegel.de/wissenschaft/medizin/herz-studie-koerperliche-bewegung-laesst-neue-muskelzellen-und-blutgefaesse-spriessen-a-050a5ede-b4da-43f3-888f-471d0e3d7d99

Longitudinal analyses of gender differences in first authorship publications related to COVID-19. Lerchenmüller C, Schmallenbach L, Jena AB, Lerchenmueller MJ.BMJ Open. 2021 Apr 5;11(4):e045176. doi: 10.1136/bmjopen-2020-045176.PMID: 33820790 Free PMC article.

Exercise training reverses cardiac aging phenotypes associated with heart failure with preserved ejection fraction in male mice. Roh JD, Houstis N, Yu A, Chang B, Yeri A, Li H, Hobson R, Lerchenmüller C, Vujic A, Chaudhari V, Damilano F, Platt C, Zlotoff D, Lee RT, Shah R, Jerosch-Herold M, Rosenzweig A.Aging Cell. 2020 Jun;19(6):e13159. doi: 10.1111/acel.13159. Epub 2020 May 22.PMID: 32441410 Free PMC article.

CITED4 Protects Against Adverse Remodeling in Response to Physiological and Pathological Stress. Lerchenmüller C, Rabolli CP, Yeri A, Kitchen R, Salvador AM, Liu LX, Ziegler O, Danielson K, Platt C, Shah R, Damilano F, Kundu P, Riechert E, Katus HA, Saffitz JE, Keshishian H, Carr SA, Bezzerides VJ, Das S, Rosenzweig A.Circ Res. 2020 Aug 14;127(5):631-646. doi: 10.1161/CIRCRESAHA.119.315881. Epub 2020 May 18.PMID: 32418505 Free PMC article.

Lerchenmüller C, Hilfiker-Kleiner D „Cardiology and cardiovascular research in Germany: 5 years of gender demographics” (Clinical Research Cardiology. Feb;108(2):218-220. doi: 10.1007/s00392-018-1335-y)

Vujic A*, Lerchenmüller C*, Wu TD, Guillermier C, Rabolli CP, Gonzalez E, Senyo SE, Liu X, Guerquin-Kern JL, Steinhauser ML, Lee RT, Rosenzweig A "Exercise induces new cardiomyocyte generation in the adult mammalian heart” (Nature Communications. 1659 (2018), doi:10.1038/s41467-018-04083-1) *Authors contributed equally
Press release: Harvard Gazette

Lerchenmüller C, Lerchenmueller MJ#, Sorenson O. "Long-term Analysis of Sex Differences in Prestigious Authorships in Cardiovascular Research Supported by the NIH” (Circulation. 2018;137:880–882) # Co-corresponding authors

Lerchenmüller C, Heissenberg J, Damilano F, Bezzeridis J, Krämer I, Bochaton-Piallat ML, Hirschberg K, Busch M, Katus HA, Peppel K, Rosenzweig A, Busch H, Boerries, M#, Most P “S100A6 regulates endothelial cell cycle progression by attenuating antiproliferative STAT1 signaling” (Arterioscler Thromb Vasc Biol. 2016 Sep;36(9):1854-67) #Co-corresponding authors 

Bezzeridis V, Platt C, Lerchenmüller C, Paruchuri K, Oh NL, Xiao C, Cao Y, Mann N, Spiegelman B, Rosenzweig A “CITED4 induces physiologic hypertrophy and promotes functional recovery after ischemic injury” (JCI Insight. 2016 Jun 16;1(9). pii: e85904)

Lerchenmüller C, Rosenzweig A “Mechanisms of Exercise-Induced Cardiac Growth“
(Drug Discovery Today 2014 Jul;19(7):1003-9)

Sen A, Ren S, Lerchenmüller C, Sun J, Weiss N, Most P, Peppel K “MicroRNA-138 Regulates Hypoxia-Induced Endothelial Cell Dysfunction by Targeting S100A1” (PLOS one 2013; 8(11): e78684)

Most P*, Lerchenmüller C, Rengo G, Mahlmann A, Ritterhoff J, Rohde D, Goodman C, Busch CJ, Laube F, Heissenberg J, Pleger ST, Weiss N, Koch WJ, Katus HA, Peppel K “S100A1 Deficiency Impairs Postischemic Angiogenesis Via Compromised Proangiogenic Endothelial Cell Function and Nitric Oxide Synthase Regulation” (Circulation Research 2013 Jan 4;112(1):66-78) * Authors contributed equally

Brinks H, Rohde D, Voelkers M, Qiu G, Pleger ST, Herzog N, Rabinowitz J, Ruhparwar A, Silvestry S, Lerchenmüller C, Mather P, Eckhart A, Katus HA, Carrel T, Koch WJ, Most P “S100A1 genetically-targeted therapy reverses dysfunction of human failing cardiomyocytes” (Journal of the American College of Cardiology 2011; 58:966-973)

Kraus C, Rohde D, Weidenhammer C, Qiu G, Pleger ST, Völkers M, Börries M, Most P “S100A1 in cardiovascular health and disease: Closing the gap between basic science and clinical therapy” (Journal of Molecular and Cellular Cardiology 2009 Oct;47(4):445-55)

Contact

University Hospital Heidelberg

Innere Medizin III

Im Neuenheimer Feld 669
69120 Heidelberg

Tel.: 06221-5638276  

Dr. Carolin Lerchenmüller

Anfahrtsplan
Analysezentrum III