zurück zur Startseite
Zentrale Tel.: 06221-560
Ärztliche Direktion

Publikationsliste

Professorin Dr. Annette Grüters-Kieslich

(peer reviewed original articles)

1/2015 – 4/2017

Dinter J, Mühlhaus J, Jacobi SF, Wienchol CL, Cöster M, Meister J, Hoefig CS, Müller A, Köhrle J, Grüters A, Krude H, Mittag J, Schöneberg T, Kleinau G, Biebermann (2015) H.3-iodothyronamine differentially modulates α-2A-adrenergic receptor-mediated signaling.
J Mol Endocrinol. 54(3):205-16

Bennecke E, Werner-Rosen K, Thyen U, Kleinemeier E, Lux A, Jürgensen M, Grüters A, Köhler B.
Eur J Pediatr. 2015 Oct;174(10):1287-97.

Dinter J, Mühlhaus J, Wienchol CL, Yi CX, Nürnberg D, Morin S, Grüters A, Köhrle J, Schöneberg T, Tschöp M, Krude H, Kleinau G, Biebermann H.(2015) Inverse agonistic action of 3-iodothyronamine at the human trace amine-associated receptor
PLoS One. 10(2):e0117774 eCollection

Ruiz-Arana IL, Hübner A, Cetingdag C, Krude H, Grüters A, Fukami M, Biebermann H, Köhler B(2015).A novel hemizygous mutation of MAMLD1 in a patient with 46,XY complete gonadal dysgenesis.
Sex Dev. 9(2):80-5.

Fischer J, Kleinau G, Müller A, Kühnen P, Zwanziger D, Kinne A, Rehders M, Moeller LC, Führer D, Grüters A, Krude H, Brix K, Biebermann H.(2015) Modulation of monocarboxylate transporter 8 oligomerization by specific pathogenic mutations.
J Mol Endocrinol. 54(1):39-50

Ludwig S, Oertelt-Prigione S, Kurmeyer C, Gross M, Grüters-Kieslich A, Regitz-Zagrosek V, Peters H.(2015) A Successful Strategy to Integrate Sex and Gender Medicine into a Newly Developed Medical Curriculum.
J Womens Health (Larchmt). 4(12):996-1005.

Kühnen P, Clément K, Wiegand S, Blankenstein O, Gottesdiener K, Martini LL, Mai K, Blume-Peytavi U, Grüters A, Krude H.(2016) Proopiomelanocortin Deficiency Treated with a Melanocortin-4 Receptor Agonist.
N Engl J Med. 375(3):240-6.

Müller A, Niederstadt L, Jonas W, Yi CX, Meyer F, Wiedmer P, Fischer J, Grötzinger C, Schürmann A, Tschöp M, Kleinau G, Grüters A, Krude H, Biebermann H.(2016) Ring Finger Protein 11 Inhibits Melanocortin 3 and 4 Receptor Signaling.
Front Endocrinol (Lausanne). 7:109 eCollection 2016.

Kleinau G, Kalveram L, Köhrle J, Szkudlinski M, Schomburg L, Biebermann H, Grüters-Kieslich A. (2016)  Insights Into the Structural and Molecular Consequences of the TSH-β Mutation C105Vfs114X.
Mol Endocrinol.;30(9):954-64.

Kühnen P, Handke D, Waterland RA, Hennig BJ, Silver M, Fulford AJ, Dominguez-Salas P, Moore SE, Prentice AM, Spranger J, Hinney A, Hebebrand J, Heppner FL, Walzer L, Grötzinger C, Gromoll J, Wiegand S, Grüters A, Krude H.(2016) Interindividual Variation in DNA Methylation at a Putative POMC Metastable Epiallele Is Associated with Obesity.
Cell Metab. 24(3):502-9

Buonocore F, Kühnen P, Suntharalingham JP, Del Valle I, Digweed M, Stachelscheid H, Khajavi N, Didi M, Brady AF, Blankenstein O, Procter AM, Dimitri P, Wales JKH, Ghirri P, Knöbl D, Strahm B, Erlacher M, Wlodarski MW, Chen W, Kokai GK, Anderson G, Morrogh D, Moulding DA, McKee SA, Niemeyer CM, Grüters A*, Achermann JC* (* geteilte Letztautorenschaft) (2017) Somatic mutations and progressive monosomy modify SAMD9-related phenotypes i n humans.
J Clin Invest. 127(5):1700-1713

Bennecke E, Thyen U, Grüters A, Lux A, Köhler B.(2017)
Health-related quality of life and psychological well-being in adults with     differences/disorders of sex development.
Clin Endocrinol (Oxf).86(4):634-643.

Weber S, Grüters-Kieslich A.(2017) Rare Diseases
Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz. 60(5):477-478

Grüters-Kieslich A, Reyes M, Sharma A, Demirci C, DeClue TJ, Lankes E, Tiosano D, Schnabel D, Jüppner H.(2017) Early-onset obesity: unrecognized first evidence for Gnas mutations and methylation changes.
J Clin Endocrinol Metab. 2017. doi: 10.1210/jc.2017-00395


2004 - 2014

Wiegand S, Maikowski U, Blankenstein O, Biebermann H, Tarnow P, Grüters A (2004): Type 2 diabetes and impaired glucose tolerance in European children and adolescents with obesity – a problem that is no longer restricted to minority groups.
Eur J Endocrinol,151(2):199-206, 2004.

Schmutzler C, Hamann I, Hofmann PJ, Kovacs G, Stemmler L, Mentrup B, Schomburg L, Ambrugger P, Grüters A, Seidlova-Wuttke D, Jarry H, Wuttke W, Köhrle J (2004): Endocrine active compounds affect thyrotropin and the hormone levels in serum as well as endpoints of thyroid hormone action in liver, heart and kidney.
Toxicology  1;205(1-2):95-102

Von Heppe JH, Krude H, L’Allemand D, Schnabel D, Grüters A (2004): The use of L-T4 as liquid solution improves the practicability and individualized dosage in newborns and infants with congenital hypothyroidism.
J Pediatr Endocrinol Metab;17(7):967-74

Grüters A (2004): Characteristic features of autoimmune thyroid diseases in children.
Z Ärztl Fortbild Qualitätssich ;98 Suppl 5:67-71

Loui A, Raab A, Wagner M, Weigel H, Grüters-Kieslich A, Bratter P, Obladen M (2004): Nutrition of Very Low Birth Weight Infants Fed Human Human Milk with or without Supplemental Trace Elements: A Randomized Controlled Trial.
J Pediatr Gastroenterol Nutr, ;39(4):346-353

Friesema EC, Grueters A, Biebermann H, Krude H, von Moers A, Reeser M, Barrett TG, Mancilla EE, Svensson J, Kester MH, Kuiper GG, Balkassmi S, Uitterlinden AG, Koehrle J, Rodien P, Halestrap AP, Visser TJ (2004): Association between mutations in a thyroid hormone transporter(MCT8) and severe X-linked psychomotor retardation.
Lancet. 16; 364:1435-7

Speiser PW, Rudolf MC, Anhalt H, Camacho-Hubner C, Chiarelli F, Eliakim A, Freemark M, Gruters A, Hershkovitz E, Iughetti L, Krude H, Latzer Y, Lustig RH, Pescovitz OH, Pinhas-Hamiel O, Rogol AD, Shalitin S, Sultan C, Stein D, Vardi P, Werther GA, Zadik Z, Zuckerman-Levin N, Hochberg Z (2004): Consensus development: childhood obesity.
J Clin Endocrinol Metab. 14

Gruters A, Krude H, Biebermann H (2004): Molecular genetic defects in congenital hypothyroidism.
Eur J Endocrinol. 151:39-44

Trimborn M, Grueters A, Neitzel H, Tonnies H: First small supernumerary ring chromosome carrying 10q euchromatin in a patient with mild phenotype characterized by molecular cytogenetic techniques and review of the literature.
Cytogenet Genome Res.108(4):278-82.


Wiegand S, Dannemann A, Vahabzadeh Z, Ernst M, Krude H, Grüters A (2005): Wer braucht was? Neue Ansätze der multidisziplinären Diagnostik und Therapie adipöser Kinder und Jugendlicher in einer multiethnischen Großstadt. Bundesgesundheitsbl-Gesundheitsforsch-Gesundheitsschutz  48:307-314

Kordonouri O, Hartmann R, Deiss D, Wilms M, Grüters-Kieslich A (2005): Natural course of autoimmune throiditis in type 1 diabetes: association with gender, age, diabetes duration, and puberty.
Arch Dis Child 90:411-14

Grüters A (2005): Entwicklung und Entwicklungsstörungen der Hoden.
Monatsschr Kinderheilk  153:424-29, 2005.

Eiholzer U, L’allemand D, Rousson V, Schlumpf M, Gasser T, Girard J, Grüters A, Simoni M (2006): Hypothalamic and Gonadal Components of Hypogonadism in Boys with Prader-Labhart-Willi-Syndrome.
J Clin Endocrinol Metab 91, 892-8

Elsner A, Tarnow P, Schaefer M, Ambrugger P, Krude H, Grüters A, Biebermann H (2006): MC4R oligomerizes independently of extracellular cysteine residues.
Peptides 27, 372-9.

Biebermann H, Ambrugger P, Tarnow P, von Moers A, Schweizer U, Grüters A (2005): Extended clinical phenotype, endocrine investigations and functional studies of a loss-of-function mutation A150V in the thyroid hormone specific transporter MCT8.
Eur J Endocrinol 153(3):359-366

Czernichow P, Clayton P, Grüters A, Soder O (2005): New section: novel insights from clinical experience.
Horm Res 63(4):193, 2005.

Grüters A (2005): The pediatric-to-adult transit clinic as a quality-securing measure in endocrinological diseases.
MMW Fortschr Med 10;147(10);29, 31-2, 2005.

Wiegand S, Dannemann A, Krude H, Grüters A (2005): Impaired glucose tolerance and type 2 diabetes mellitus: a new field for pediatrics in Europe.
Int J Obes (Lond.), 29 (2):136-42

H. Biebermann, T. Castañeda, F. van Landeghem, A. von Deimling, F. Escher, G. Brabant, J. Hebebrand, A. Hinney, M. Tschöp, A. Grüters, H. Krude (2006): A role for beta-melanocyte-stimulating hormone in human body-weight regulation.
Cell Metabolism, 3: 141-146

M.O. Savage, F.g. Cassorla, P. D. Gluckman, A. Grueters-Kieslich, P. Raghupathy, M.Silink, P.Czernichow, F. Chiarelli, A.D. Rogol, P. Crock, C. T. Cowell, K. Fujieda, I. Arnhold (2006): Global Inequalities in Paediatric Endocrine Practice: Statement of Minimal Acceptable Care.
Hormone Research 65:111-113

Alt B, Elsalini OA, Schrumpf P, Haufs N, Lawson ND, Schwabe GC, Mundlos S, Gruters A, Krude H, Rohr KB (2006): Arteries define the position of the thyroid gland during its developmental relocalisation.
Development. 133(19):3797-804

Najmabadi H, Motazacker MM, Garshasbi M, Kahrizi K, Tzschach A, Chen W, Behjati F, Hadavi V, Nieh SE, Abedini SS, Vazifehmand R, Firouzabadi SG, Jamali P, Falah M, Seifati SM, Gruters A, et.al. (2007): Homozygosity mapping in consanguineous families reveals extreme heterogeneity of non-syndromic autosomal recessive mental retardation and identifies 8 novel gene loci.
Hum Genet.121, 43-8

Jansen J, Friesema EC, Kester MH, Milici C, Reeser M, Gruters A, Visser T  (2007).: Functional analysis of MCT8 mutations identified in patients with X-linked psychomotor retardation and elevated serum triiodothyronine.
J Clin Endocrinol Metab. 92, 2378-81

Metzler M, Luedecke DK, Saeger W, Grueters A, Haberl H, Kiess W, Repp R, Rascher W, Doetsch J (2006). Low prevalence of Gs alpha mutations in śomatotroph adenomas of children and adolescents.
Cancer Genet Cytogenet. 15;166(2):146-51

Grüters A, Krude H (2007). Update on the management of congenital hypothyroidism.
HHorm Res. 2007;68 Suppl 5:107-11.

Al Taji E, Biebermann H, Limanova Z, Hnikova O, Zikmund J, Dame C, Gruters A, Lebl J, Krude H. (2007): Screening for mutations in transcription factors in a Czech cohort of 170 patients with congenital and early-onset hypothyroidism: identification of a novel PAX8 mutation in dominantly inherited early-onset non-autoimmune hypothyroidism.
Eur J Endocrinol. 2007 May;156(5):521-9.

Wiefel A., Titze K., Kuntze L., Winter M., Seither C., Witte B., Lenz K., Grüters A. & Lehmkuhl U.(2007): Diagnostic classification of mental disorders in infants and toddlers age 0 to 5.
Prax Kinderpsychol K: 56(1) 59-81

Schmutzler C, Bacinski A, Gotthardt I, Huhne K, Ambrugger P, Klammer H, Schlecht C, Hoang-Vu C, Gruters A, Wuttke W, Jarry H, Kohrle J. (2007): The ultraviolet filter benzophenone 2 interferes with the thyroid hormone axis in rats and is a potent in vitro inhibitor of human recombinant thyroid peroxidase.
Endocrinology. Jun;148(6):2835-44.

Staubert C, Tarnow P, Brumm H, Pitra C, Gudermann T, Gruters A, Schoneberg T, Biebermann H, Rompler H (2007).: Evolutionary aspects in evaluating mutations in the melanocortin 4 receptor.
Endocrinology.148, 4642-8

Gruters A (2007).: Thyroid hormone transporter defects.
Endocr Dev. 10:118-26

Kohler B, Lin L, Ferraz-de-Souza B, Wieacker P, Heidemann P, Schroder V, Biebermann H, Schnabel D, Gruters A, Achermann JC. (2008): Five novel mutations in steroidogenic factor 1 (SF1, NR5A1) in 46,XY patients with severe underandrogenization but without adrenal insufficiency.
Hum Mutat. 29, 59-64

Wiegand S, Richardt A, Remer T, Wudy SA, Tomlinson JW, Hughes B, Gruters A, Stewart PM, Strasburger CJ, Quinkler M (2007): Reduced 11{beta}-hydroxysteroid dehydrogenase type 1 activity in obese boys.
Eur J Endocrinol. 157(3):319-324.

Raile K, Klopocki E, Wessel T, Deiss D, Horn D, Müller D, Ullmann R, Grüters A.(2008): HNF1B abnormality (mature-onset diabetes of the young 5) in children and adolescents: high prevalence in autoantibody-negative type 1 diabetes with kidney defects.
Diabetes Care. 31(11) e83

Moreno JC, Klootwijk W, van Toor H, Pinto G, D'Alessandro M, Lèger A, Goudie D, Polak M, Grüters A, Visser TJ. Mutations in the iodotyrosine deiodinase gene and hypothyroidism.
N Engl J Med. 2008 Apr 24;358(17):1811-8

Korte A, Lehmkuhl U, Goecker D, Beier KM, Krude H, Grüters-Kieslich A. (2008): Gender identity disorders in childhood and adolescence: currently debated concepts and treatment strategies.
Dtsch Arztebl Int. 2008 Nov;105(48):834-41.

Tarnow P., Rediger A., Brumm H., Ambrugger P., Rettenbacher E., Widhalm K., Hinney A., Kleinau G., Schaefer M., Hebebrand J., Krause G., Grüters A. & Biebermann H.(2008): A heterozygous mutation in the third transmembrane domain causes a dominant-negative effect on signalling capability of the MC4R.
Obes Facts: 1(3) 155-62

Wirth EK, Roth S, Blechschmidt C, Hölter SM, Becker L, Racz I, Zimmer A, Klopstock T, Gailus-Durner V, Fuchs H, Wurst W, Naumann T, Bräuer A, de Angelis MH, Köhrle J, Grüters A, Schweizer U. (2009): Neuronal 3',3,5-triiodothyronine (T3) uptake and behavioral phenotype of mice deficient in Mct8, the neuronal T3 transporter mutated in Allan-Herndon-Dudley syndrome.
J Neurosci., 29(30) 9439-49

Raile K, Klopocki E, Holder M, Wessel T, Galler A, Deiss D, Müller D, Riebel T, Horn D, Maringa M, Weber J, Ullmann R, Grüters A. (2009): Expanded clinical spectrum in hepatocyte nuclear factor 1b-maturity-onset diabetes of the young.
J Clin Endocr Metab.  94(7) 2658-64

Rajab A, Kelberman D, de Castro SC, Biebermann H, Shaikh H, Pearce K, Hall CM, Shaikh G, Gerrelli D, Grueters A, Krude H, Dattani MT (2008). Novel mutations in LHX3 are associated with hypopituitarism and sensorineural hearing loss.
Hum Mol Genet. 17(14):2150-9.

Bau AM, Ernert A, Schenk L, Wiegand S, Martus P, Grüters A, Krude H (2008). Is there a further acceleration in the age at onset of menarche? A cross-sectional study in 1840 school children focusing on age and bodyweight at the onset of menarche.
Eur J Endocrinol.160(1):107-13

Kuehnen P, Grueters A, Krude H (2009). Two puzzling cases of thyroid dysgenesis.
Horm Res.71 Suppl 1:93-7.

Köhler B, Lin L, Mazen I, Cetindag C, Biebermann H, Akkurt I, Rossi R, Hiort O, Grüters A, Achermann JC. (2009) The spectrum of phenotypes associated with mutations in steroidogenic factor 1 (SF-1, NR5A1, Ad4BP) includes severe penoscrotal hypospadias in 46,XY males without adrenal insufficiency.
Eur J Endocrinol. 161(2):237-42.

Rediger A, Tarnow P, Bickenbach A, Schaefer M, Krude H, Gruters A, Biebermann H. (2009). Heterodimerization of hypothalamic G-protein-coupled receptors involved in weight regulation.
Obes Facts; 2(2):80-6.

Hennermann JB, Roloff S, Gellermann J, Grüters A, Klein J.( 2009). False-positive newborn screening mimicking glutaric aciduria type I in infants with renal insufficiency.
J Inherit Metab Dis. 1, 1-10

Kinne A, Roth S, Biebermann H, Köhrle J, Grüters A, Schweizer U.(2009). Surface translocation and tri-iodothyronine uptake of mutant MCT8 proteins are cell type-dependent.
J Mol Endocrinol. 43(6):263-71.

Wiegand S, l'Allemand D, Hübel H, Krude H, Bürmann M, Martus P, Grüters A, Holl RW. (2010): Metformin and placebo therapy both improve weight management and fasting insulin in obese insulin-resistant adolescents: a prospective, placebo-controlled, randomized study.
Eur J Endocrinol. 163(4):585-92.

Sauber J, Grothe J, Behm M, Scherag A, Grallert H, Illig T, Hinney A, Hebebrand J, Wiegand S, Grüters A, Krude H, Biebermann H. (2010). Association of variants in gastric inhibitory polypeptide receptor gene with impaired glucose homeostasis in obese children and adolescents from Berlin.
Eur J Endocrinol. 2010 Aug;163(2):259-64.

Winkler F, Kleinau G, Tarnow P, Rediger A, Grohmann L, Gaetjens I, Krause G, L'Allemand D, Grüters A, Krude H, Biebermann H. (2010) A new phenotype of nongoitrous and nonautoimmune hyperthyroidism caused by a heterozygous thyrotropin receptor mutation in transmembrane helix 6.
J Clin Endocrinol Metab.;95(8):3605-10

Kinne A, Kleinau G, Hoefig CS, Grüters A, Köhrle J, Krause G, Schweizer U. (2010): Essential molecular determinants for thyroid hormone transport and first structural implications for monocarboxylate transporter 8.
J Biol Chem. ;285(36):28054-63.

Thorwarth A, Mueller I, Biebermann H, Ropers HH, Grueters A, Krude H, Ullmann R. (2010). Screening chromosomal aberrations by array comparative genomic hybridization in 80 patients with congenital hypothyroidism and thyroid dysgenesis.
J Clin Endocrinol Metab.;95(7):3446-52.

Maimoun L, Philibert P, Cammas B, Audran F, Bouchard P, Fenichel P, Cartigny M, Pienkowski C, Polak M, Skordis N, Mazen I, Ocal G, Berberoglu M, Reynaud R, Baumann C, Cabrol S, Simon D, Kayemba-Kay's K, De Kerdanet M, Kurtz F, Leheup B, Heinrichs C, Tenoutasse S, Van Vliet G, Grüters A, Eunice M, Ammini AC, Hafez M, Hochberg Z, Einaudi S, Al Mawlawi H, Del Valle Nuñez CJ, Servant N, Lumbroso S, Paris F, Sultan C. (2011): Phenotypical, Biological, and Molecular Heterogeneity of 5{alpha}-Reductase Deficiency: An Extensive International Experience of 55 Patients.
J Clin Endocrinol Metab. 96, 296-307

Alatzoglou K.S., Kelberman D., Cowell C.T., Palmer R., Arnhold I.J.P., Melo M.E., Schnabel D., Grueters A. & Dattani M.T. (2011): Increased transactivation associated with SOX3 polyalanine tract deletion in a patient with hypopituitarism.
J Clin Endocr Metab: 96 E685-90

Biebermann H., Winkler F., Handke D., Grüters A., Krude H. & Kleinau G. (2011): Molecular description of non-autoimmune hyperthyroidism at a neonate caused by a new thyrotropin receptor germline mutation.
Thyroid Res: 4 Suppl 1 S8

Braun D., Wirth E.K., Wohlgemuth F., Reix N., Klein M.O., Grüters A., Köhrle J. & Schweizer U. (2011): Aminoaciduria, but normal thyroid hormone levels and signalling, in mice lacking the amino acid and thyroid hormone transporter
Slc7a8. Biochem J: 439 249-55

Brumm H., Mühlhaus J., Bolze F., Scherag S., Hinney A., Hebebrand J., Wiegand S., Klingenspor M., Grüters A., Krude H. & Biebermann H. (2012): Rescue of Melanocortin 4 Receptor (MC4R) Nonsense Mutations by Aminoglycoside-Mediated Read-Through. Obesity 20(5):1074-8

Kleinau G., Schweizer U., Kinne A., Köhrle J., Grüters A., Krude H. & Biebermann H. (2011): Insights into molecular properties of the human monocarboxylate transporter 8 by combining functional with structural information.  Thyroid Res: 4 Suppl 1 S4

Köhler B., Biebermann H., Friedsam V., Gellermann J., Maier R.F., Pohl M., Wieacker P., Hiort O., Grüters A. & Krude H. (2011): Analysis of the Wilms' tumor suppressor gene (WT1) in patients 46,XY disorders of sex development. 
J Clin Endocr Metab: 96 E1131-6,


Schuchmann S., Hauck S., Henning S., Grüters-Kieslich A., Vanhatalo S., Schmitz D. & Kaila K. (2011): Respiratory alkalosis in children with febrile seizures.
Epilepsia: 52 1949-1955,

Wirth E.K., Sheu S.Y., Chiu-Ugalde J., Sapin R., Klein M., Mossbrugger I., Quintanilla-Martinez L., Hrabé de Angelis M., Krude H., Riebel T., Rothe K., Köhrle J., Schmid K.W., Schweizer U. & Grüters A. (2011): Monocarboxylate transporter 8 deficiency: altered thyroid morphology and persistent high triiodothyronine/thyroxine ratio after thyroidectomy.
Eur J Endocrinol: 165 555-61

Kleinau G., Pratzka J., Nürnberg D., Grüters A., Führer-Sakel D., Krude H., Köhrle J., Schöneberg T. & Biebermann H. (2011): Differential modulation of Beta-adrenergic receptor signaling by trace amine-associated receptor 1 agonists.
PLoS ONE;6:e27073

Rediger A., Piechowski C.L., Yi C.X., Tarnow P., Strotmann R., Grüters A., Krude H., Schöneberg T., Tschöp M.H., Kleinau G. & Biebermann H. (2011): Mutually opposite signal modulation by hypothalamic heterodimerization of ghrelin and melanocortin-3 receptors.
J Biol Chem 2011; 286:39623-31

Biebermann H., Winkler F., Handke D., Teichmann A., Gerling B., Cameron F., Eichhorst J., Grüters A., Wiesner B., Kühnen P., Krude H. & Kleinau G. (2012): New pathogenic thyrotropin receptor mutations decipher differentiated activity switching at a conserved helix 6 motif of family A GPCR.
J Clin Endocr Metab;97:E228-32

Brumm H., Mühlhaus J., Bolze F., Scherag S., Hinney A., Hebebrand J., Wiegand S., Klingenspor M., Grüters A., Krude H. & Biebermann H. (2012): Rescue of melanocortin 4 receptor (MC4R) nonsense mutations by aminoglycoside-mediated read-through.
Obesity (Silver Spring);20:1074-81

Grüters A. & Krude H. (2012): Detection and treatment of congenital hypothyroidism.
Nat Rev Endocrinol, 8:104-13


Köhler B., Kleinemeier E., Lux A., Hiort O., Grüters A., Thyen U. & the DSD Network Working Group (2012): Satisfaction with genital surgery and sexual life of adults with XY disorders of sex development: results from the German clinical evaluation study.
J Clin Endocr Metab, 97:577-88


Kuehnen P., Mischke M., Wiegand S., Sers C., Horsthemke B., Lau S., Keil T., Lee Y.A., Grueters A. & Krude H. (2012): An Alu element-associated hypermethylation variant of the POMC gene is associated with childhood obesity.
Plos Genet 2012;8(3)


Mühlhaus J., Pütter C., Brumm H., Grallert H., Illig T., Scherag S., Reinehr T., Pott W., Albayrak O., Wang H.J., Bau A.M., Wiegand S., Grüters A., Krude H., Hebebrand J., Hinney A., Biebermann H. & Scherag A. (2012): Do common variants separate between obese melanocortin-4 receptor gene mutation carriers and non-carriers? The impact of cryptic relatedness.
Horm Res Paediatr; 77:358-68

Rediger A., Piechowski C.L., Habegger K., Grüters A., Krude H., Tschöp M.H., Kleinau G. & Biebermann H. (2012): MC4R dimerization in the paraventricular nucleus and GHSR/MC3R heterodimerization in the arcuate nucleus: is there relevance for body weight regulation?
Neuroendocrinology, 95:277-88

Tarnow P., Rediger A., Schulz A., Grüters A. & Biebermann H. (2012): Identification of the translation start site of the human melanocortin 3 receptor.
Obes Facts 2012;5:45-51

Kleinau G., Neumann S., Grüters A., Krude H. & Biebermann H. (2013): Novel insights on thyroid-stimulating hormone receptor signal transduction.
Endocr Rev 2013;34:691-724

Müller A., Kleinau G., Piechowski C.L., Müller T.D., Finan B., Pratzka J., Grüters A., Krude H., Tschöp M. & Biebermann H. (2013): G-protein coupled receptor 83 (GPR83) signaling determined by constitutive and zinc(II)-induced activity.
PLoS ONE;8:e53347

Piechowski C.L., Rediger A., Lagemann C., Mühlhaus J., Müller A., Pratzka J., Tarnow P., Grüters A., Krude H., Kleinau G. & Biebermann H. (2013): Inhibition of melanocortin-4 receptor dimerization by substitutions in intracellular loop 2.
J Mol Endocrinol;51:109-18

Kühnen P., Turan S., Fröhler S., Güran T., Abali S., Biebermann H., Bereket A., Grüters A., Chen W. & Krude H. (2014): Identification of PENDRIN (SLC26A4) mutations in patients with congenital hypothyroidism and "apparent" thyroid dysgenesis. J Clin Endocr Metab;99:E169-76

Tantawy S., Mazen I., Soliman H., Anwar G., Atef A., El-Gammal M., El-Kotoury A., Mekkawy M., Torky A., Rudolf A., Schrumpf P., Grüters A., Krude H., Dumargne M.C., Astudillo R., Bashamboo A., Biebermann H. & Köhler B. (2014): Analysis of the gene coding for steroidogenic factor 1 (SF1, NR5A1) in a cohort of 50 Egyptian patients with 46,XY disorders of sex development.
Eur J Endocrinol;170:759-67

Thorwarth A., Schnittert-Hübener S., Schrumpf P., Müller I., Jyrch S., Dame C., Biebermann H., Kleinau G., Katchanov J., Schülke M., Ebert G., Steininger A., Bönnemann C., Brockmann K., Christen H.J., Crock P., Dezegher F., Griese M., Hewitt J., Ivarsson S., Hübner C., Kapelari K., Plecko B., Rating D., Stoeva I., Ropers H.H., Grüters A., Ullmann R. & Krude H. (2014): Comprehensive genotyping and clinical characterisation reveal 27 novel NKX2-1 mutations and expand the phenotypic spectrum.
J Med Genet. 2014 Jun;51(6):375-87.

Auler JO, Canny B, Fukuhara S, Ganten D, Grüters-Kieslich A, Klag MJ, Wong JE. (2014)What is the World Health Summit for?
Lancet. 384:26.

Müller A, Leinweber B, Fischer J, Müller TD, Grüters A, Tschöp MH, Knäuper V, Biebermann H, Kleinau G.(2014)The extracellular N-terminal domain of G-protein coupled receptor 83 regulates signaling properties and is an intramolecular inverse agonist.
BMC Res Notes. 7:913.


1993 - 2003

Grüters A, Delange F, Giovanelli G, Klett M, Torresani T, Grant D, Hnikova H, Mäenpäa J, Toublanc J (1993): Guidelines for neonatal screening for congenital hypothyroidism.
Eur J Pediatr 152: 974-975

Torresani T, Grüters A, Scherz R, Burckhardt J, Harras A, Zachmann M (1994): Improving the efficacy of a newborn screening for congenital hypothyroidism by adjusting the cut-off level of 17-hydroxyprogesterone to gestational age.
Screening 3:77-84

Monch E. & Gruters A (1993).: Screening of newborns,
Dtsch Krankenpflegez: 46(2) 77-9

Gruters A., Delange F., Giovannelli G., Klett M., Rochiccioli P., Torresani T., Grant D., Hnikova O., Maenpaa J., Rondanini G.F. & et A. (1994) Guidelines for neonatal screening programs for congenital hypothyroidism.European Society for Pediatric Endocrinology Working Group on CongenitalHypothyroidism.
Horm Res: 41(1) 1-2

Grüters A, Finke R, Krude H, Meinhold H (1994): Etiological grouping of permanent congenital hypothyroidism with a thyroid gland in situ.
Horm Res 41:3-9

Perrild H, Grüters A, Feldt-Rasmussen U, Grant D, Martino E, Kayser I, Delange F (1994): Diagnosis and treatment of thyrotoxicosis in childhood.
Eur J Endocrinol 131: 467-473

Sperling K, Pelz J, Wegener R, Dörries A, Grüters A, Mikkelsen M (1994): Significant increase in trisomy 21 nine months after the Chernobyl reactor accident: temporal correlation or causal relation.
Brit Med J 309: 158-162

Moers A, Großklaus R, Hesse V, Grüters A (1994): Jodversorgung Neugeborener in Berlin.
Kinderarzt 8: 932-935

König S, Mlageni F, Grüters A, Haas N, Schulze C, Weber B, Scheffner D (1994): Einfluß von Hypoglykämien auf die nächtliche Hormonsekretion bei jugendlichen Diabetikern.
Sozialpädiatrie 16:231-234

Grüters A, Liesenkötter K, Willgerodt H (1995): Difference in iodine nutrition in newborns after the reunification.
New Engl J Med 333(21):1429-1430

Göpel W, Schnabel D, Völger P, Grüters A (1996): Severe hypokalemia due to hyperreninemia and secondary hyperaldosteronism in a boy with pheochromocytoma.
Eur J Pediatr 155: 147-148

Krude H, Biebermann H, Göpel W, Grüters A (1996): The TSH receptor gene as a candidate gene for congenital hypothyroidism with thyroid dysgenesis.
Exp Clin Endocrinol Diabetes 104: 117-120

Grüters A, Köhler B, Wolf A, Söling A, de Vijlder L, Krude H, Biebermann H (1996): Screening for mutations of the human thyroid peroxidase gene in patients with congenital hypothyroisim.
Exp Clin Endocrinol Diabetes 104: 121-123

Grüters A (1996): Screening for congenital hypothyroidism: effectiveness and clinical outcome.
Baillieres Clinical Pediatrics 4: 259-277

K. Schwab, Sohlemann P, Gerlich M, Bröcker M, Petrykowski W, Holzapfel H, Paschke R, Grüters A, Derwahl M (1996):Mutations of the TSH receptor as a cause of congenital hypothyroidism.
Exp Clin Endocrinol Diabetes 104: 124-128

Liesenkötter K, Göpel W, Bogner U, Stach B, Grüters A (1996): Earliest prevention of endemic goiter by iodine supplementation during pregnancy.
Eur J Endocrinol 134: 443-448

Herrmann M.E., Dannemann A., Gruters A., Radisch B., Dudenhausen J.W., Bergmann R., Coumbos A., Weitzel H.K. & Wahn U. (1996): Prospective study of the atopy preventive effect of maternal avoidance of milk and eggs during pregnancy and lactation.
Eur J Pediatr: 155(9) 770-4

l’Allemand D, Keller E, Hoeppner W, Serban A, Morel Y, Grüters A (1996): Nonclassical adrenal hyperplasia due to 21-hydroxylase deficiency: Does the genotype predict the clinical manifestation.
Endocrine Res 22: 735-739

Köhler B, Schnabel D, Biebermann H, Grüters A (1996): Transient congenital hypothyroidism and hyperthyrotropinemia: normal thyroid function and physical devlopment at the age of 6-14 years.
J Clin Endocrinol Metab 81:1563-1566

Roth C, Siggelkow H, Grüters A, Hüfner M, Lakomek M (1997): Neonataler Morbus Basedow bei Zwillingen einer Mutter mit schwerer T3-Hyperthyreose.
Dtsch Med Wschr 122: 572-577

Willichowski E, Grüters A, Kruse K, Rating D, Beetz R, Korenke C, Ernst B, Christen HJ, Hanefeld F (1997): Hypoparathyroidism and deafness associated with pleioplasmic large scale rearrangements of the mitochondrial DNA: A clinical and molecular genetic study of children with Kearns Sayre syndrome.
Pediatr Res 42: 193-200

Stoeva I, Peneva L, Grigorova R, Vassileva B, Brumm H, Grüters A (1997): Neonatal TSH-screening- an instrument of iodine supplementation monitoring in Bulgaria -a preliminary report.
J Exp Clin Endocrinol Diabetes 105: 51-55

Danne T, Grüters A, Wladimirova A, Weber B, Horn R, Mayr B, Brabant G (1997): Gender specific differences of serum leptin in obese and normal weight adolescents: studies in type 1 diabetes mellitus and Turner syndrome.
Horm Res 48: 193-107

Grüters A, Liesenkötter K, Zapico M, Jenner A, Dütting C, Pfeiffer E, Lehmkuhl U (1997) :Results of the screening program for congenital hypothyroidism in Berlin (1978-1995). Ext Clin Endocrinol Diabetes 105: 28-32
25.    Biebermann H, Schöneberg T, Gudermann T, Grüters A (1997): Congenital hypothyroidism caused by mutations of the thyrotropin receptor gene.
New Engl J Med 336: 1390-1391

Liesenkötter K, Kiebler A, Stach B, Willgerodt H, Grüters A (1997): Small thyroid volumes and normal iodine excretion in Berlin schoolchildren indicates normalization of iodine supply.
Exp Clin Endocrinol Diab 105: 46-51

Biebermann H, Schöneberg T, Krude H, Schultz G, Gudermann T, Grüters A (1997): Mutations of the Thyrotropin receptor gene causing thyroid hypoplasia and persistent hypothyroidism.
J Clin Endocrinol Metab 82: 3471-3481

Krude H, Biebermann, H, Krohn HP, Dralle H, Grüters A (1997): Congenital hyperthyroidism.
Exp Clin Endocrinol Diabetes 105:6-12

Waldschmidt J, L’Allemand D, Grüters-Kieslich A, Lawin-Mosecker C, Lempe M (1997): Anwendung von PVP-Jod bei operierten Neugeborenen.
Pädiat Prax 50: 631-638

Biebermann H, Schöneberg T, Schulz A, Krause G, Grüters A, Schultz G, Gudermann T (1998): A conserved tyrosine residue (Y601) in transmembrane domain 5 of the human thyrotropin receptor serves as a molecular switch to determine G-proteincoupling.
FASEB J. 12(14):1461-71

Schöneberg T, Schulz A, Biebermann H, Grüters A, Grimm T, Hubschmann K, Filler G, Gudermann T, Schultz G (1998): V2 vasopressin receptor dysfunction in nephrogenic diabetes insipidus caused by different molecular mechanisms.
Hum Mutat. 12 (3):196-205

Grüters A (1998): Screening and early detection of congenital hypothyroidism in Germany - still insufficient.
Internist (Berl). 39 (6):574-6

Grüters A (1998): Treatment of Graves' disease in children and adolescents.
Horm Res 49 (6):255-7

Krude H, Biebermann H, Luck W, Horn R, Brabant G, Grüters A (1998): Severe early-onset obesity, adrenal insufficiency and red hair pigmentation caused by POMC mutations in humans.
Nat Genet 19 (2):155-7

Macchia PE, Lapi P, Krude H, Pirro MT, Missero C, Chiovato L, Souabni A,Baserga M, Tassi V, Pinchera A, Fenzi G, Grüters A, Busslinger M, Di Lauro R (1998): PAX8 mutations associated with congenital hypothyroidism caused by thyroid dysgenesis.
Nat Genet 19 (1):83-6

Grüters A, Schöneberg T, Biebermann H, Krude H, Krohn HP, Dralle H, Gudermann T (1998): Severe congenital hyperthyroidism caused by a germ-line neo mutation in the extracellular portion of the thyrotropin receptor. J Clin Endocrinol Metab 83 (5):1431-6

Coyle B, Reardon W, Herbrick JA, Tsui LC, Gausden E, Lee J, Coffey R, Grueters A, Grossman A, Phelps PD, Luxon L, Kendall-Taylor P, Scherer SW,Trembath RC (1998): Molecular analysis of the PDS gene in Pendred syndrome.
Hum Mol Genet 7 (7):1105-12

Grüters A, Schumm-Draeger PM (1998): Diagnostik und Therapie von Störungen der Schilddrüsenfunktion bei Jugendlichen.
Der Kinderarzt 29:44-50, 1998.

Grüters A (1999): Ocular manifestations in children and adolescents with thyrotoxicosis.
Exp Clin Endocrinol Diabetes 107:172-4, 1999.

Biebermann H, Liesenkötter KP, Emeis M, Obladen M, Grüters A (1999): Severe congenital hypothyroidism due to a homozygous mutation of the betaTSH gene.
Pediatr Res 46 (2):170-3, 1999.

Toublanc JE, Grüters-Kieslich A, Donaldson M, Ferrandez-Longas A, Giovannelli G, Honour JW, Hnikova O, Klett M, Larsson A, de Muinck Keizer-Schrama SMPF, Torresani T (1999): Revised Guidelines for Neonatal Screening Programmes for Primary Congenital Hypothyroidism.
Horm Res 52:49-52

Krude H, Schnabel D, Luck W, Grüters A (1999): Implications of the phenotype of POMC deficiency for the role of POMC peptides in skin physiology.
Ann N Y Acad Sci 20;885:419-421

Grüters A, Krude H, Biebermann H, Liesenkötter KP, Schöneberg T, Gudermann T (1999): Alterations of neonatal thyroid function.
Acta Paediatr Suppl. 1999 Feb;88 (428):17-22.

Köhler B, Schumacher V, Schulte-Overberg U, Biewald W, Lennert T, l’Allemand D, Royer-Pokora B, Grüters A (1999): Bilateral Wilms tumor in a boy with severe hypospadias and cryptochidism due to a heterozygous mutation in the WT1 gene.
Pediatr Res 1999, Feb 45(2):187-90.

Netchine I, Sobrier ML, Krude H, Schnabel D, Magnie M, Cacheux V, von Moers A, Grüters A, Amselem S (2000): Mutations in LHX3 gene result in a new syndrome revealed by combined pituitary hormone deficiency.
Nat Genet; Jun;25(2):182-6.

Brabant G, Horn R, von zur Mühlen A, Mayr B, Wurster U, Heidenreich F, Schnabel D, Grüters-Kieslich A, Zimmermann-Belsing T, Feldt-Rasmussen U (2000): Free and protein bound leptin are distinct and independently controlled fat regulation.
Diabetologia Apr. 43(4): 438-42

Stichel H, l’Allemand D, Grüters A (2000): Thyroid Function and Obesity in Children and Adolescents.
Horm Res 54(1): 14-19

L’Allemand D, Tardy V, Grüters A, Schnabel D, Krude H, Morel Y (2000): How a Patient Homozygous for a 30-kb Deletion of the C4-CYP 21 Gene can have a Nonclassic Form of 21-Hydroxylase Deficiency.
J Clin Endocrinol Metab Dec;85(12): 4562-67

Pasel K, Schulz A, Timmermann K, Linnemann K, Hoeltzenbein M, Jaaskelainen J, Grüters A, Filler G, Schöneberg T (2000): Functional characterization of the molecular defects causing nephrogenic insipidus in eight families.
J. Clin Endocrinol Metab Apr;85(4): 1703-10, 2000.

Krude H, Biebermann H, Schnabel D, Ambrugger P, Grüters A (2000): Molecular pathogenesis of neonatal hypothyroidism.
Horm Res 53:12-18.

Kreissig R, Amthauer H, Krude H, Steinmüller P, Stroszczynski C, Hosten N, Grüters A, Felix R (2000): The use of FDG-PET and CT for the staging of adrenocortical carcinoma in children.
Pediatr Radiol May; 30(5):182-6.

Krude H, Grüters A: Implications of proopiomelanocortin (POMC) mutations in humans: the POMC deficiency syndrome.
Trends Endocrinol Metab Jan-Feb 11(1):15-22.

Schnabel D, l’Allemand D, Krude H, Keller E, Grüters A (2000): Ergebnisse des Neugeborenenscreenings zur Früherkennung des Adrenogenitalen Syndroms.
Monatsschr Kinderheilkd 148: 1006-1011

Grüters A, Holl R, Hindmarsh P, Kruse K (2000): Europäisches Weiterbildungsprogramm in pädiatrischer Endokrinologie und Diabetologie.
Monatsschr Kinderheilkd 148:909-914

Köhler B, Schumacher V, l’Allemand D, Royer-Pokora B, Grüters A (2001): Germline Wilms tumor suppressor gene (WT1) mutation leading to isolate malformation without Wilms tumor or nephropathy.
J Pediatr 138(3):421-424.

Ambrugger P, Stoeva I, Biebermann H, Torresani T, Leitner C, Grüters A (2001): Novel mutations of the thyroid peroxidase gene in patients with permanent congenital hypothyroidism.
Eur J of Endocrinol 145:19-24

Müsebeck J, Mohnike K, Beye P, Tönnies H, Neitzel H, Schnabel D, Grüters A, Wieacker PF, Stumm M (2001): Short stature homeobox-containing gene deletion screening by fluorescence in situ hybridisation in patients with short stature.
Eur J Pediatr 160: 561-565

Grüters A, Krude H, Biebermann H, Netchine S, Amselem I (2001): The molecular basis of new paediatric endocrine syndromes: POMC, LHX3 and NKX2.1 deficiency syndromes: POMC, LHX3 and NKX2.1 deficiency syndromes.
An Esp Pediatri May;54 (Suppl 1):28-30

Biebermann H, Schöneberg T, Hess C, Germak J, Gudermann T, Grüters A (2001): The first activating TSH receptor mutation in transmembrane domain 1 identified in a family with nonautoimmune hyperthyroidism.
J Clin Endocrinol Metab, Sept 86(9):4429-33

Krude H, Schütz B, Biebermann H, von Moers A, Schnabel D, Neitzel H, Tönnies H, Weise D, Lafferty A, Schwarz S, DeFelice M, von Deimling A, van Landeghem F, DiLauro R, Grüters A (2002): Choreathetosis, hypothyroidism, and pulmonary alterations due to human NKX2-1 haploinsufficiency.
J Clin Invest 109:475-480

Kordonouri O, Hartmann R, Grüters-Kieslich A, Knip M, Danne T (2002): Age-specific levels of diabetes-related GAD and IA-2 antibodies in healthy children and adults.
J Ped Endocrin & Metabolism 15:47-52

L’Allemand D, Schmidt S, Rousson V, Brabant G, Gasser T, Grüters A (2002): Associations between body mass, leptin, IGF-I and circulating adrenal androgens in children with obesity and premature adrenarche.
Eur J Endocrin 146:1-7

Grüters A, Wiegand S, Krude H (2002): Ursachen der kindlichen Adipositas.
MMW-Fortschr Med Nr.9, (144 Jg.): 34-36

Breedveld GJ, van Dongen JWF, Danesino C, Guala A, Percy AK, Dure LS, Harper P, Lazarou LP, van der Linde H, Joossee M, Grüters A, MacDonald ME, de Vries BBA, Arts WFM, Oostra BA, Krude H, Heutink P (2002): Mutations in TITF-1 are associated with benign hereditary chorea.
Hum Mol Gen, Vol.11, No 8:971-9


Grüters A, Jenner A, Krude H (2002): Long-term consequences of congenital hypothyroidism in the era of screening programmes.
Best. Practice & Research Clinical Endocrinolgy and Metabolism, Vol 16 No.2,: 369-382

Kordonouri O, Klinghammer A, Lang EB, Grüters-Kieslich A, Grabert M, Holl RW (2002): Thyroid Autoimmunity in Children and Adolescents with Type 1 Diabetes.
Diabetes Care, Vol 25: 1346-1350

Kordonouri O, Deiss D, Danne T, Dorow A, Bassier C, Grüters-Kieslich A (2002): Predictivity of thyroid autoantibodies for the development of thyroid disorders in children and adolescents with Type I diabetes.
Diabet Med, Jun;19(6):518-21

Brumm H, Pfeufer A, Biebermann H, Schnabel D, Deiss D, Grüters A (2002): Congenital Central Hypothyroidism due to Homozygous Thyrotropin beta 313DeltaT Mutation is caused by a Founder Effect.
J Clin Endocrinol Metab, Oct 87(10):4811-6

Schulz A, Sangkuhl K, Lennert T, Wigger M, Price DA, Nuuja A, Grüters A, Schultz G, Schöneberg GT (2002): Aminoglycoside pretreatment partially restores the function of truncated (2) vasopressin receptors found in patients wiht nephrogenic diabetes insipidus.
J Clin Endocrinol Metab, 87(11):5247-57

Grüters A, Biebermann H, Krude H (2003): Neonatal thyroid disorders.
Horm Res 59 Suppl 1:24-9

Kabelitz M, Liesenkötter KP, Berger B, Stäblein W, Singendonk W, Jäger-Roman E, Litzenbörger H, Ehnert B, Grüters-Kieslich A (2003): The prevalence of thyroid autoantibodies and autoimmune thyroidits in children and adolescents in an iodine replete area
Eur J Endocrin 148(3):301-7.

Tarnow P, Schöneberg T, Krude H, Grüters A, Biebermann H (2003): Mutationally Induced Disulfide Bond Formation within the Third Extracellular Loop Causes Melanocortin 4 Receptor Inactivation in Patients with Obesity.
J Biol Chem, 278(49):48666-67

Krude H, Biebermann H, Grüters A (2003): Mutations in the human proopiomelanocortin gene.
Ann N Y Acad Sci, 994:233-9, 2003.

Grüters A, Biebermann H, Krude H (2003): Neonatal thyroid disorders.
Horm Res. 59 Suppl, 1;24.9. 2003.

Krude H, Biebermann H, Schnabel D, Tansek MZ, Theunissen P, Mullis PE, Grüters A (2003): Obesity due to proopiomelanocortin deficiency: three new cases and treatment trials with thyroid hormone and ACTH4-10.
J Clin Endocrinol Metab, 88(10):4633-40

Biebermann H, Krude H, Elsner A, Chubanov V, Gudermann T, Grüters A (2003): Autosomal-Dominant Mode of Inheritance of a Melanocortin-4 Receptor Mutation in a Patient with Severe Early-Onset Obesity Is Due to a Dominant-Negativ Effect Caused by Receptor Dimerization.
Diabetes, 52(12):2984-88, 2003

Muther S, Krude H, Jäger R, Rhode W, Grüters A, Rossi R (2003): Hypothyroidism in dizygotic premature twins due to excessive prepartal vaginal iodine application.
Zentralbl Gynakol,125(6):226-8, 2003.


1982 - 1992

Grüters A, Korth-Schütz S (1982): Longitudinal study of DHEAS in preterm and fullterm newborns.
J Clin Endocrinol Metab 55: 314-318

L’Allemand D, Grüters A, Heidemann P, Schürnbrandt P (1983): Iodine induced alterations of thyroid function in newborns after perinatal exposure to PVP-iodine.
J Pediatr 102: 935-940


Grüters A
, l’Allemand D, Heidemann P, Schürnbrandt P (1983): Incidence of iodine contamination in transient neonatal hyperthyreotropinemia.
Eur J Pediatr 140: 299-302


Grüters A, l’Allemand D, Beyer P, Eibs G, Korth-Schütz S, Helge H, Oberdisse U, Schwartz D, Weber B (1983): Neugeborenen-Hypothyreosescreening in Berlin 1978-1982.
Monatsschr Kinderheilk 131: 100-104


Lakshmanan J, Beri U, Peerhentupa J, Grüters A, Kim H, Macaso T, Fisher DA (1984): Aquisition of nerve growth factor responsiveness to thyroxine administration in neonatal mice.
J Neurosci Res 12: 71-76


Lakshmanan J, Peerhentupa J, Hoath S, Kim H, Grüters A, Fisher DA (1984): EGF in mouse ocular tissue: effects of thyroxine and exogenous EGF.
Pediatr Res 19:853-857


Grüters A
, Lakshmanan J, Alm J, Fisher DA (1985): EGF in mouse milk during early lactation: Lack of dependency on submandibular glands.
Pediatr Res 19: 853-857


Grüters A
, Lakshmanan J, Tarris R, Alm J, Fisher DA (1985): NGF in mouse milk during gestation.
Pediatr Res 19: 934-938

Lakshmanan J, Perheentupa J, Hoath SB, Kim H, Grüters A, Odell C, Fisher DA: Epidermal growth factor in mouse ocular tissue: effects of thyrotoxine and exogenous epidermal growth factor.
Pediatr Res 1985 Mar 19(3):315-9.


L’Allemand D, Grüters A, Beyer P, Weber B (1987): Iodine in contrast agents and skin disinfectants is the major cause of transient hypothyroidism in premature infants in intensive care.
Horm Res: 42-48


Danne T, Grüters A, Schnabel K, Burger W, l’Allemand D, Helge H, Weber B (1988): Longterm monitoring of treatment with human growth hormone by serial determinations of procollagen III peptide related antigens in serum. Pediatr Res 23: 167-172


Grüters A
, Heidemann P, Schlüter H, Stubbe P, Weber B, Helge H (1989): Effect of different estrogen doses on final height reduction in girls with constitutional tall stature.
Eur J Pediatr 149:11-15


Bogner U, Grüters A, Sigle B, Schleusener H (1989): Cytotoxic antibodies in congenital hypothyroidism.
J Clin Endocrinol Metab 68: 671 –676


Danne T, Grüters A, Schuppan D, Quandas N, Weber B (1989): Relationship of procollagen III peptide related antigens in serum to somatic growth in healthy children and children with growth disorders.
J Pediatr 114: 257-261


Rother K, Zachmann M, Kempken B, Grüters A, Schnabel D, L’Allemand D, Häusler, Frisch H (1989): Effect of human growth hormone on urinary 15N nitrogen balance in girls with Turner Syndrome as compared to children with growth hormone deficiency.
Horm Res 32: 66-70


Grüters A
, Schlüter H, Heidemann P, Weber B (1990): Hochwuchstherapie bei Mädchen.
Pädiatr Grenzgebiete 29:153-158


Schleusener H, Bogner U, Peters H, Kotulla P, Schmieg D, Grüters A (1991): The relevance of genetic susceptibility in Graves’ disease and autoimmune thyroiditis.
Exp Clin Endocrinol Diabetes 97:127-132


Toublanc JE, Grüters A, Bogner U, Fulla Y, Dugue MA (1991): Etude de l’ADCC et des anticorps bloquant la croissance thyroidienne dans l’hypothyroidie congenitale.
Arch Fr Pediatr 48:89-95


Grüters A
(1992): Congenital Hypothyroidism. Pediatr Annals 21: 15-21

Print Diese Seite per E-Mail weiterempfehlen