Working groups
Translational Surgical Oncology
Working group leader
Team
cand. med. Elena Dahm
Dr. Clemens Franz
cand. med. Justus Gaukel
Melanie Höfler
Dr. Anna-Katharina König
Dr. Lukas Liesenfeld
cand. med. Ella Leugner
Michaela Magenreuter
Dr. Julian Musa
Dr. Nikolai Schleußner
Prof. Dr. Martin Schneider
Maria Thomalla-Starzl
Dr. Franziska Willis
cand. med. Uraz Yasar
Shuai Yuan
Funding
Selected publications
P. Radhakrishnan, N. Ruh, J.M. Harnoss, J. Kiss, M. Mollenhauer, A.L. Scherr, L. Platzer, T. Schmidt, K. Podar, J.T. Opferman, J. Weitz, H. Schulze-Bergkamen, B. Koehler, A. Ulrich and M. Schneider. Prolyl hydroxylase 3 attenuates MCL-1-mediated ATP production to suppress the metastatic potential of colorectal cancer cells. Cancer Res 76, 2219-2230 (2016).
J.M. Harnoss, L. Platzer, J. Burhenne, P. Radhakrishnan, J. Cai, M. Strowitzki, J. Weiss, A.S. Ritter, M. Mollenhauer, T. Schmidt, A. Ulrich, W.E. Haefeli and M. Schneider. Prolyl hydroxylase inhibition enhances liver regeneration without induction of tumor growth. Ann Surg 265(4), 782-791 (2017).
M.J. Strowitzki, P. Radhakrishnan, S. Pavicevic, J. Scheer, G. Kimmer, A.S. Ritter, C. Tuffs, C. Volz, F. Vondran, J.M. Harnoss, J. Klose, T. Schmidt and M. Schneider. High hepatic expression of PDK4 improves survival upon multimodal treatment of colorectal liver metastases. Br J Cancer 120(7), 675-688 (2019).
A.N. Holowatyj, B. Gigic; E. Herpel, A. Scalbert, M. Schneider and C.M. Ulrich. Distinct molecular phenotype of sporadic colorectal cancers among young patients based on multi-omics analysis. Gastroenterology 158(4), 1155-1158 (2020).
M.J. Strowitzki, G. Kimmer, J. Wehrmann, A.S. Ritter, P. Radhakrishnan, V.M. Opitz, C. Tuffs, M. Biller, J. Kugler, U. Keppler, J.M. Harnoss, J. Klose, T. Schmidt, A. Blanco, C.T. Taylor and M. Schneider. Inhibition of HIF-prolyl hydroxylases improves healing of intestinal anastomoses. JCI Insight 6 (8), 139191 (2021).
L.F. Liesenfeld, B. Wagner, H.C. Hillebrecht, M. Brune, C. Eckert, J. Klose, T. Schmidt, M.W. Büchler and M. Schneider. HIPEC-induced acute kidney injury: a retrospective clinical study and preclinical model. Ann Surg Oncol 2021 Jul 14 [Epub ahead of print].