Kliniken & Institute … Institute Pathologisches Institut… Angewandte… Forschung HPV-assoziierte Tumoren… ETiCCS

Emering Technologies in Cervical Cancer Screening (ETiCCS)


Cervical cancer is a major health problem in Sub-Sahara-Africa.

What we do

Currently we are running a diagnostic implementation program (emerging technologies in cervical cancer screening, ETiCCS) in Africa to test whether biomarker-based cervical cancer screening technologies may help to establish and / or improve cervical cancer screening in resource poor areas.

Innovative and integrated  IT solutions to facilitate data exchange from patients to their doctors, nurses and lab technicians are provided by cloud-based data management systems developed by SAP.


Key publications

  • Ngugi CW, Schmidt D, Wanyoro K, Boga H, Wanzala P, Muigai A, Mbithi J, von Knebel Doeberitz M, Reuschenbach M.  p16(INK4a)/Ki-67 dual stain cytology for cervical cancer screening in Thika district, Kenya. Infectious Infect Agent Cancer. 2015 Aug 11;10:25.
  • Bergeron C, Ronco G, Reuschenbach M, Wentzensen N, Arbyn M, Stoler M, von Knebel Doeberitz M. The clinical impact of using p16(INK4a) immunochemistry in cervical histopathology and cytology: an update of recent developments. Int J Cancer. 2015 Jun 15;136(12):2741-51.
  • von Knebel Doeberitz M, Reuschenbach M, Schmidt D, Bergeron C. Biomarkers for  cervical cancer screening: the role of p16(INK4a) to highlight transforming HPV infections. Expert Rev Proteomics. 2012 Apr;9(2):149-63.