Personen
Portrait von Prof. Dr. med. Gregor Warnecke

Prof. Dr. med. Gregor Warnecke

Leitender Oberarzt (Klinik für Herzchirurgie)
Sektionsleiter (Sektion Chirurgische Therapie des terminalen Herzversagens)

Schwerpunkt

Erwachsenenherzchirurgie, Klappenchirurgie, Bypasschirurgie, Minimal-invasive Chirurgie, Herzunterstützungssysteme/Kunstherzen, Herztransplantation


Ärztlicher / Beruflicher Werdegang

seit Januar 2020

Stellvertretender Klinikdirektor und leitender Oberarzt der Klinik für Herzchirurgie am Universitätsklinikum Heidelberg, Leiter der Sektion „Chirurgische Therapie des terminalen Herzversagens“ ebenda

September 2017 – Dezember 2019

Leitender Oberarzt und „Profilbereichsleiter Transplantation“ mit den Bereichen „Lungentransplantation“, „Herztransplantation“, „Transplantationsambulanz“ und „ECMO-Therapie“

September 2017 – September 2019

Ernennung zum außerplanmäßigen Professor an der MHH

Januar 2016 – Dezember 2019

Leitender Oberarzt der Abteilung

August 2010

Habilitation: „T-Zell Regulation von Alloantigenen – Experimentelle Induktion und Einfluss auf das Langzeitüberleben von Lungentransplantaten“, Klinik für Herz-, Thorax-, Transplantations- und Gefäßchirurgie der MHH
und Venia legendi für das Fach Herzchirurgie

August 2010 – Januar 2016

Oberarzt der Abteilung

seit April 2010

Leitende Tätigkeit für den Bereich „Lungen- und Herzlungentransplantation“ der Abteilung für HTTG-Chirurgie der MHH, Entwicklung und Umsetzung eines innovativen Team-orientierten Leitungskonzeptes des Transplantationsbereiches der Abteilung

Mai 2009

Facharzt für Herzchirurgie

Juli 2001 – Mai 2009

Arzt im Praktikum und Assistenzarzt in der Klinik für Thorax-, Herz- und Gefäßchirurgie der MHH,
Leiter: Prof. Dr. A. Haverich
(beurlaubt als DFG-Stipendiat 04/2004 – 03/2006)

Oktober 1997 – Juni 2003

Dissertation: „Therapie des pulmonalen Ischämie-Reperfusionsschadens mit inhaliertem Stickstoffmonoxid und exogenem Surfactant bei Minipigs”, Klinik für Thorax-, Herz- und Gefäßchirurgie der MHH, Leiter: Prof. Dr. A. Haverich

Oktober 1994 – Mai 2001

Studium der Humanmedizin, Medizinische Hochschule Hannover

Wissenschaftlicher Werdegang

August 2010

Habilitation:
„T-Zell Regulation von Alloantigenen – Experimentelle Induktion und Einfluss auf das Langzeitüberleben von Lungentransplantaten“, Klinik für Herz-, Thorax-, Transplantations- und Gefäßchirurgie der MHH
Venia legendi für das Fach Herzchirurgie

April 2004 – März 2006

Emmy-Noether-Stipendium der DFG:
Nuffield Department of Surgery, Transplantation Immunology Laborato-ry, Leiterin: Prof. K.J. Wood, D.Phil., John Radcliffe Hospital, University of Oxford, Oxford, U.K.

seit Januar 2003

Approbation

Oktober 1997 – Juni 2003

Dissertation:
„Therapie des pulmonalen Ischämie-Reperfusionsschadens mit inhaliertem Stickstoffmonoxid und exogenem Surfactant bei Minipigs”, Klinik für Thorax-, Herz- und Gefäßchirurgie der MHH, Leiter: Prof. Dr. A. Haverich

April 1999 – November 1999

Auslandsaufenthalt zu Forschungszwecken:
Untersuchungen an hCD46-transgenen Schweinen zur kardialen Xe-notransplantation in nicht-humane Primaten im Dept. of Cardiothoracic Surgery and Transplantation, Leiter: Prof. C.G.A. McGregor, Mayo Cli-nic, Rochester, MN, USA

Oktober 1994 – Mai 2001

Studium der Humanmedizin, Medizinische Hochschule Hannover

Auszeichnungen

2020

Franz J. Koehler Preis der Deutschen Gesellschaft für Thorax-, Herz- und Ge-fäßchirurgie für herausragende Leistungen in Forschung oder klinischer Praxis auf dem Gebiet der Organprotektion, 7.500 €  

2015

Tätigkeitsbericht 2014/15 der Überwachungskommission gem. § 11 Abs. 3 S. 4 TPG und Prüfungskommission gem. § 12 Abs. 5 S. 4 TPG der Bundesärztekammer, Prüf-zeitraum 2010-2012: Keine Auffälligkeiten im Herztransplantationsprogramm (26 von 51 Patienten wurden überprüft) und im Lungentransplantationsprogramm der MHH (56 von 378 Patienten wurden überprüft)

2013

Rudolf-Schoen-Preis der Gesellschaft der Freunde der Medizinischen Hochschule Hannover für die Arbeit: „Normothermic perfusion of donor lungs for pre-servation and assessment with the Organ Care System Lung before - bilateral trans-plantation: a pilot study of 12 patients”, 10.000 €

2010

TTS 2010 ICTS New Key Opinion Leader Award für die Arbeit: „Extracorporeal membrane oxygenation in fully awake patients with right heart failure as bridge to transplantation”, 3.000 $

2006

AST World Transplant Congress Young Investigator Award für die Arbeit: „Alloantigen-Reactive CD25+CD4+ Regulatory T Cells Generated in vivo Inhibit Transplant Arteriosclerosis”, 1.000 $

Philip K. Caves Award der International Society for Heart and Lung Transplan-tation für die Arbeit: „Pulmonary allograft tolerance in pigs is associated with increased frequency and regulatory function of CD4+CD25+ T cells”, 1.000 $

2004

Nachwuchsförderpreis der Deutschen Gesellschaft für Thorax-, Herz- und Ge-fäßchirurgie für die Dissertationsschrift „Therapie des pulmonalen Ischämie-Reperfusionsschadens mit inhaliertem Stickstoffmonoxid und exogenem Surfactant bei Minipigs”, 1.000 €

2002

Posterpreis der Deutschen Gesellschaft für Radioonkologie, Jahrestagung, 29.6.-2.7. 2002, Berlin, für die Arbeit: „Induktion spenderspezifischer Toleranz durch selektive Thymusbestrahlung und niedrigdosierte Ganzkörperbestrahlung in einem al-logenen porcinen Lungentransplantationsmodell“, 1.000 €

Drittmitteleinwerbungen

2020

Beantragt: DFG Forschergruppe EVOC (Ex Vivo Organ Conditioning), überarbeite-ter Vorantrag 12/2019 gemeinsam von Forschern aus Essen, Heidelberg und Hanno-ver eingereicht, designierter Sprecher: Prof. G. Warnecke, designierter Co-Sprecher: Prof. T. Minor, Universität Duisburg-Essen

seit 2018

DFG Clinician Scientist Program ME 3696/3-1 Young Academy PRACTIS (Program of Hanover Medical School for Clinician Scientists) als Mitan-tragsteller, Hauptantragstellerin: Frau Prof. A. Melk, MHH

2018 – 2021

DFG Einzelantragsförderung WA 1700/7-1, gemeinsam mit Frau Privat-dozentin C. Figueiredo: „Generierung immunologisch unsichtbarer Organe durch ex vivo MHC Silencing zur Verhinderung der Abstoßung in einem Miniaturschwein-Lungentransplantationsmodell“

2017 – 2020

DFG Einzelantragsförderung WA 1700/5-1, gemeinsam mit Frau Prof. C. Falk, Herrn Prof. D.D. Jonigk und Herrn Prof. J. Schultze: „Populationsstruktur myeloider Zellen in gesunden und erkrankten humanen Lungengewebe“

2016 – 2019

Klinische Forschergruppe 311, DFG, Teilprojekt 08, gemeinsam mit Frau Prof. Dr. A. Prasse: „Rolle und Reversibilität des durch mechanischen Stress in-duzierten aberranten Remodellings der idiopathischen Lungenfibrose (IPF)“

2013 – 2014

Integriertes Forschungs- und Behandlungszentrum Transplantation, BMBF: Projekt CBT 2: „Induction of T cell regulation in lung transplantation by donor-specific splenocyte infusion“, MHH

2015 – 2020

Deutsches Zentrum für Lungenforschung, Folgeförderung 2015-2020: Projekt ELD 1.2.2

2011 – 2015

Deutsches Zentrum für Lungenforschung, BMBF 2011-2015: Projekt ELD 1.2.2:  „Mechanisms of bronchiolitis obliterans syndrome“, Standort BREATH, MHH; ge-meinsam mit Prof. U. Maus, MHH

2015 – 2020

Deutsches Zentrum für Lungenforschung, Folgeförderung 2015-2020: Projekt ELD 1.1.2 gleichen Titels

2011 – 2015

Deutsches Zentrum für Lungenforschung, BMBF 2011-2015: Projekt ELD 1.1.2: „Immunologic transplant tolerance“, Standort BREATH, MHH

2015 – 2020

Deutsches Zentrum für Lungenforschung, Folgeförderung 2015-2020: Projekt ELD 1.1.1 gleichen Titels

2011 – 2015

Deutsches Zentrum für Lungenforschung, BMBF 2011-2015: Projekt ELD 1.1.1: „Immuno-phenotyping of clinical lung transplant recipients before and after transplantation“, Standort BREATH, MHH; gemeinsam mit Prof. R. Hatz, München

2015 – 2019

Sonderforschungsbereich 738, Folgeförderung 2015-2019: Projekt B3 gleichen Titels, gemeinsam mit Prof. Dr. C. Falk

2011 – 2015

Sonderforschungsbereich 738, Folgeförderung 2011-2015: Projekt B3 gleichen Titels

2007 – 2011

Sonderforschungsbereich 738, DFG 2007-2011: Projekt B3 „T cell mediated anti-donor immune responses of human transplant recipients in vivo – impact on the development of transplant arteriosclerosis”, MHH

2004 – 2006

Emmy-Noether-Programm, DFG, 2004 – 2006: „Einfluss der Induktion spenderspezifischer Transplantationstoleranz auf die chronische Abstoßungsreaktion”
Stipendium an der University of Oxford, Großbritannien, für 2 Jahre

2007 – 2010

Klinische Forschergruppe 123 „Lungentransplantation”, Folgeförderung 2007-2010: „Induction of T cell regulation in a model of living-related donor lung transplantation in miniature swine”; Klinische Forschergruppe 123 “Lungentransplantation”, MHH, Projekt 4; gemeinsam mit PD Dr. M. Strüber

2004 – 2007

Klinische Forschergruppe 123 „Lungentransplantation”, DFG 2004 – 2007: „Lung Preservation for Transplantation from Heart Beating and Non Heart Beating Donors in a Porcine Model”; der Medizinischen Hochschule Hannover, Projekt 1; gemeinsam mit Dr. S. Fischer

 

Gutachtertätigkeiten

seit 2018

Reviewer: New England Journal of Medicine

seit 2017

Reviewer: The Lancet Respiratory Medicine

seit 2015

Reviewer: Thoracic and Cardiovascular Surgeon

Reviewer: Journal of Heart and Lung Transplantation

Gutachter: Deutsche Herzstiftung

seit 2014

Reviewer: American Journal of Transplantation

Reviewer: The Lancet

Associate Editor: Transplantation

seit 2007

Gutachter: DFG

seit 2006

Reviewer: European Journal of Cardiothoracic Surgery

Member of the Editorial Board: Transplantation

seit 2005

Reviewer: Annals of Thoracic Surgery

Weitere akademische Tätigkeiten

1.    Principal Investigator im Deutschen Zentrum für Lungenforschung (DZL)


2.    Gewähltes Mitglied des Scientific Advisory Board (SAB) des Integrierten Forschungs- und Behandlungszentrums Transplantation (IFB-Tx) an der MHH, 2013 - 2015


3.    Principal Investigator des internationalen, multizentrischen, prospektiven, kontrollierten INSPIRE trials zur Untersuchung der Konservierung von Spenderlungen zur Transplantation


4.    Principal Investigator des internationalen, multizentrischen, prospektiven, EXPAND trials zur Untersuchung der Konservierung und Verbesserung von Lungen mit erweiterten Spenderkriterien zur Transplantation


5.    Leiter der Arbeitsgruppe “Lung Allocation Score” der Thorakalen Organkommission der DTG/DGTHG, 2014 – 2016


6.    Stellvertretender Vorsitzender der Thorakalen Organkommission der DTG/DGTHG, ab 2016


7.    Mitglied des Eurotransplant Thoracic Advisory Committee (EThAC), ab 2016


8.    Mitglied des Beirates des Zentralen Tierlaboratoriums der MHH


9.    Mitglied der Prüfungskommission 201 des Landesprüfungsamtes für den Dritten Teil der Ärztlichen Prüfung


10.    Mitglied des Promotionsausschusses 2.3.2 “Chirurgie” der Sektion II der MHH


11.    Mitglied der Programmkommission des Else-Kröner-Promotionskollegs (Klinisches StrucMed-Programm) der MHH, 2014 – 2016


12.    Gewähltes Mitglied der Eurotransplant Scientific Registry Working Group, ab 06/2017


13.    Mitglied des wissenschaftlichen Beirates der Deutschen Transplantationsgesellschaft (DTG), ab 10/2017


14.    Tagungspräsident der Jahrestagung 2019 der DTG in Hannover (gemeinsam mit Prof. A. Haverich)

 

Publikationen

2020

Rivinius R, Kaya Z, Schramm R, Boeken U, Provaznik Z, Heim C, Knosalla C, Schoenrath F, Rieth A, Berchtold-Herz M, Barten MJ, Rauschning D, Mücke VT, Heyl S, Pistulli R, Grinninger C, Hagl C, Gummert JF, Warnecke G, Schulze PC, Katus HA, Kreusser MM, Raake PW (2020)

COVID-19 among heart transplant recipients in Germany: a multicenter survey.

Clin Res Cardiol. 2020 Aug 11:1-9. doi: 10.1007/s00392-020-01722-w. Online ahead of print. PMID: 32783099

 

Becher PM, Schrage B, Weimann J, Smits J, Magnussen C, Reichenspurner H, Goßling A, Rodrigus I, Dumfarth J, de Pauw M, François K, van Caenegem O, Ancion A, Van Cleemput J, Milicic D, Moza A, Schenker P, Röhrich L, Schönrath F, Thul J, Steinmetz M, Schmack B, Ruhparwar A, Warnecke G, Rojas SV, Sandhaus T, Haneya A, Eifert S, Welp H, Ablonczy L, Wagner F, Westermann D, Bernhardt AM, Knappe D, Blankenberg S, Kirchhof P, Zengin E, Sinning C (2020)

Clinical characteristics and outcomes of patients with adult congenital heart disease listed for heart and heart‒lung transplantation in the Eurotransplant region.

J Heart Lung Transplant. 2020 Jul 25:S1053-2498(20)31663-6. doi: 10.1016/j.healun.2020.07.012. Online ahead of print. PMID: 32778365

 

Moyé S, Bormann T, Maus R, Sparwasser T, Sandrock I, Prinz I, Warnecke G, Welte T, Gauldie J, Kolb M, Maus UA (2020)

Regulatory T Cells Limit Pneumococcus-Induced Exacerbation of Lung Fibrosis in Mice.

J Immunol. 2020 Mar 25. pii: ji1900980. doi: 10.4049/jimmunol.1900980. [Epub ahead of print]

 

Ius F, Müller C, Sommer W, Verboom M, Hallensleben M, Salman J, Siemeni T, Kühn C, Avsar M, Bobylev D, Poyanmehr R, Erdfelder C, Böthig D, Carlens J, Bayir L, Hansen G, Blasczyk R, Falk C, Tecklenburg A, Haverich A, Tudorache I, Schwerk N, Warnecke G (2020)

Six-year experience with treatment of early donor-specific anti-HLA antibodies in pediatric lung transplantation using a human immunoglobulin-based protocol.

Pediatr Pulmonol. 2020 Mar;55(3):754-764. doi: 10.1002/ppul.24639. Epub 2020 Jan 7.

 

Werlein C, Seidel A, Warnecke G, Gottlieb J, Laenger F, Jonigk D (2020)

Lung Transplant Pathology: An Overview on Current Entities and Procedures.

Surg Pathol Clin. 2020 Mar;13(1):119-140. doi: 10.1016/j.path.2019.11.003. Review.

 

Obed D, Fleissner F, Martens A, Cebotari S, Haverich A, Warnecke G, Ismail I (2020)

Total Arterial Revascularization with Radial Artery and Internal Thoracic Artery T-Grafts Is Associated with Superior Long-Term Survival in Patients Undergoing Coronary Artery Bypass Grafting.

Ann Thorac Cardiovasc Surg. 2020 Feb 20;26(1):30-39. doi: 10.5761/atcs.oa.19-00226. Epub 2020 Jan 18.

 

Delgado SJ, Dehmel S, Twisterling E, Wichmann J, Jonigk D, Warnecke G, Braubach P, Fieguth HG, Wilkens L, Dahlmann F, Kaup FJ, Eggel A, Knauf S, Sewald K, Braun A (2020)

Disruptive anti-IgE inhibitors prevent mast cell-dependent early airway response in viable atopic lung tissue.

J Allergy Clin Immunol. 2020 Feb;145(2):719-722.e1. doi: 10.1016/j.jaci.2019.11.002. Epub 2019 Dec 16. No abstract available.

 

Ius F, Salman J, Knoefel AK, Sommer W, Nakagiri T, Verboom M, Siemeni T, Poyanmehr R, Bobylev D, Kuehn C, Avsar M, Erdfelder C, Hallensleben M, Boethig D, Hecker H, Schwerk N, Mueller C, Welte T, Falk C, Preissler G, Haverich A, Tudorache I, Warnecke G (2020)

Increased frequency of CD4+ CD25high CD127low T cells early after lung transplant is associated with improved graft survival - a retrospective study.

Transpl Int. 2020 Jan 6. doi: 10.1111/tri.13568. [Epub ahead of print]

 

2019

Fleißner F, Salman J, Naqizadah J, Avsar M, Meier J, Warnecke G, Kühn C, Cebotari S, Ziesing S, Haverich A, Tudorache I (2019)

Minimally Invasive Surgery in Mitral Valve Endocarditis.

Thorac Cardiovasc Surg. 2019 Dec;67(8):637-643. doi: 10.1055/s-0038-1675342. Epub 2018 Oct 31.

 

Rojas SV, Trinh-Adams ML, Uribarri A, Fleissner F, Iablonskii P, Rojas-Hernandez S, Ricklefs M, Martens A, Rümke S, Warnecke G, Cebotari S, Haverich A, Ismail I (2019)

Early surgical myocardial revascularization in non-ST-segment elevation acute coronary syndrome.

J Thorac Dis. 2019 Nov;11(11):4444-4452. doi: 10.21037/jtd.2019.11.08.

 

Loor G, Warnecke G, Villavicencio MA, Smith MA, Kukreja J, Ardehali A, Hartwig M, Daneshmand MA, Hertz MI, Huddleston S, Haverich A, Madsen JC, Van Raemdonck D (2019)

Portable normothermic ex-vivo lung perfusion, ventilation, and functional assessment with the Organ Care System on donor lung use for transplantation from extended-criteria donors (EXPAND): a single-arm, pivotal trial.

Lancet Respir Med. 2019 Nov;7(11):975-984. doi: 10.1016/S2213-2600(19)30200-0. Epub 2019 Aug 1.

 

Ius F, Moscalenco D, Boethig D, Tudorache I, Haverich A, Warnecke G, Cebotari S (2019)

Cardiac valve operations after solid organ transplantation: A single-center experience.

J Thorac Cardiovasc Surg. 2019 Oct 21. pii: S0022-5223(19)32243-3. doi: 10.1016/j.jtcvs.2019.10.032. [Epub ahead of print]

 

Jonigk D, Stark H, Braubach P, Neubert L, Shin HO, Izykowski N, Welte T, Janciauskiene S, Warnecke G, Haverich A, Kuehnel M, Laenger F (2019)

Morphological and molecular motifs of fibrosing pulmonary injury patterns.

J Pathol Clin Res. 2019 Oct;5(4):256-271. doi: 10.1002/cjp2.141. Epub 2019 Sep 25.

 

Warnecke G, Haverich A, Sommer W (2019)

Abstracts of the 28th Annual Meeting of the German Transplantation Society, Hannover, Germany, 17-19 October 2019.

Transpl Int. 2019 Oct;32 Suppl 3:5-52. doi: 10.1111/tri.13503. No abstract available.

 

Hansmann G, Koestenberger M, Alastalo TP, Apitz C, Austin ED, Bonnet D, Budts W, D'Alto M, Gatzoulis MA, Hasan BS, Kozlik-Feldmann R, Kumar RK, Lammers AE, Latus H, Michel-Behnke I, Miera O, Morrell NW, Pieles G, Quandt D, Sallmon H, Schranz D, Tran-Lundmark K, Tulloh RMR, Warnecke G, Wåhlander H, Weber SC, Zartner P (2019)

2019 updated consensus statement on the diagnosis and treatment of pediatric pulmonary hypertension: The European Pediatric Pulmonary Vascular Disease Network (EPPVDN), endorsed by AEPC, ESPR and ISHLT.

J Heart Lung Transplant. 2019 Sep;38(9):879-901. doi: 10.1016/j.healun.2019.06.022. Epub 2019 Jun 21.

 

Uribarri A, Rojas SV, Hanke JS, Dogan G, Siemeni T, Kaufeld T, Ius F, Goecke T, Rojas-Hernandez S, Warnecke G, Bara C, Avsar M, Haverich A (2019)

Prognostic Value of the Nutritional Risk Index in Candidates for Continuous Flow Left Ventricular Assist Device Therapy.

Rev Esp Cardiol (Engl Ed). 2019 Aug;72(8):608-615. doi: 10.1016/j.rec.2018.05.029. Epub 2018 Aug 2. English, Spanish.

 

Kordes A, Preusse M, Willger SD, Braubach P, Jonigk D, Haverich A, Warnecke G, Häussler S (2019)

Genetically diverse Pseudomonas aeruginosa populations display similar transcriptomic profiles in a cystic fibrosis explanted lung.

Nat Commun. 2019 Jul 30;10(1):3397. doi: 10.1038/s41467-019-11414-3.

 

Ius F, Haverich A, Warnecke G (2019)

Cardiac Transplantation Across Preformed HLA-antibody Barriers.

Transplantation. 2019 Jul;103(7):1304-1305. doi: 10.1097/TP.0000000000002504. No abstract available.

 

Siemeni T, Knöfel AK, Ius F, Sommer W, Salman J, Böthig D, Falk CS, Tudorache I, Haverich A, Warnecke G (2019)

Transplant arteriosclerosis in humanized mice reflects chronic lung allograft dysfunction and is controlled by regulatory T cells.

J Thorac Cardiovasc Surg. 2019 Jun;157(6):2528-2537. doi: 10.1016/j.jtcvs.2019.01.134. Epub 2019 Feb 28.

 

Salman J, Ius F, Sommer W, Siemeni T, Fleissner F, Alhadidi H, Kugler C, Avsar M, Haverich A, Warnecke G, Tudorache I, Kuhn C (2019)

Long-Term Results of Bilateral Lung Transplantation in Patients With End-Stage Pulmonary Lymphangioleiomyomatosis.

Prog Transplant. 2019 Jun;29(2):115-121. doi: 10.1177/1526924819835815.

 

Sommer W, Kirschner H, Ius F, Salman J, Siemeni T, Bobylev D, Avsar M, Kuehn C, Greer M, Gottlieb J, Rahmel A, Welte T, Haverich A, Tudorache I, Warnecke G (2019)

Transplantation of donor lungs with pulmonary embolism - a retrospective study.

Transpl Int. 2019 Jun;32(6):658-667. doi: 10.1111/tri.13407. Epub 2019 Feb 21.

 

Sommer W, Ius F, Müller C, Bobylev D, Kuehn C, Avsar M, Salman J, Siemeni T, Miha O J, Horke A, Haverich A, Tudorache I, Schwerk N, Warnecke G (2019)

Extended criteria donor lungs do not impact recipient outcomes in pediatric transplantation.

J Heart Lung Transplant. 2019 May;38(5):560-569. doi: 10.1016/j.healun.2019.02.012. Epub 2019 Feb 27.

 

Ius F, Hoeper MM, Fegbeutel C, Kühn C, Olsson K, Koigeldiyev N, Tudorache I, Warnecke G, Optenhöfel J, Puntigam JO, Schäfer A, Meyer BC, Hinrichs JB, Bauersachs J, Haverich A, Cebotari S (2019)

Extracorporeal membrane oxygenation and surgical embolectomy for high-risk pulmonary embolism.

Eur Respir J. 2019 Apr 25;53(4). pii: 1801773. doi: 10.1183/13993003.01773-2018. Print 2019 Apr. No abstract available.

 

Figueiredo C, Carvalho Oliveira M, Chen-Wacker C, Jansson K, Höffler K, Yuzefovych Y, Pogozhykh O, Jin Z, Kühnel M, Jonigk D, Wiegmann B, Sommer W, Haverich A, Warnecke G, Blasczyk R (2019)

Immunoengineering of the Vascular Endothelium to Silence MHC Expression During Normothermic Ex Vivo Lung Perfusion.

Hum Gene Ther. 2019 Apr;30(4):485-496. doi: 10.1089/hum.2018.117. Epub 2018 Nov 20.

 

Neubert L, Borchert P, Shin HO, Linz F, Wagner WL, Warnecke G, Laenger F, Haverich A, Stark H, Hoeper MM, Kuehnel M, Ackermann M, Jonigk D (2019)

Comprehensive three-dimensional morphology of neoangiogenesis in pulmonary veno-occlusive disease and pulmonary capillary hemangiomatosis.

J Pathol Clin Res. 2019 Apr;5(2):108-114. doi: 10.1002/cjp2.125. Epub 2019 Feb 27.

 

Gräger N, Leffler M, Gottlieb J, Fuge J, Warnecke G, Gutzmer R, Satzger I (2019)

Risk Factors for Developing Nonmelanoma Skin Cancer after Lung Transplantation.

J Skin Cancer. 2019 Mar 10;2019:7089482. doi: 10.1155/2019/7089482. eCollection 2019.

 

Renne J, Gutberlet M, Voskrebenzev A, Kern A, Kaireit T, Hinrichs JB, Braubach P, Falk CS, Höffler K, Warnecke G, Zardo P, Haverich A, Wacker F, Vogel-Claussen J, Zinne N (2019)

Functional Pulmonary Magnetic Resonance Imaging for Detection of Ischemic Injury in a Porcine Ex-Vivo Lung Perfusion System Prior to Transplantation.

Acad Radiol. 2019 Feb;26(2):170-178. doi: 10.1016/j.acra.2018.05.006. Epub 2018 Jun 19.

 

Sommer W, Salman J, Avsar M, Hoeffler K, Jansson K, Siemeni TN, Knoefel AK, Ahrens L, Poyanmehr R, Tudorache I, Braubach P, Jonigk D, Haverich A, Warnecke G (2019)

Prediction of transplant outcome after 24-hour ex vivo lung perfusion using the Organ Care System in a porcine lung transplantation model.

Am J Transplant. 2019 Feb;19(2):345-355. doi: 10.1111/ajt.15075. Epub 2018 Sep 12.

 

2018

Renne J, Gutberlet M, Voskrebenzev A, Kern A, Kaireit T, Hinrichs J, Zardo P, Warnecke G, Krüger M, Braubach P, Jonigk D, Haverich A, Wacker F, Vogel-Claussen J, Zinne N (2018)

Multiparametric MRI for organ quality assessment in a porcine Ex-Vivo lung perfusion system.

PLoS One. 2018 Dec 27;13(12):e0209103. doi: 10.1371/journal.pone.0209103. eCollection 2018.

 

Steinmeyer J, Becker S, Avsar M, Salman J, Höffler K, Haverich A, Warnecke G, Mühlfeld C, Ochs M, Schnapper-Isl A (2018)

Cellular and acellular ex vivo lung perfusion preserve functional lung ultrastructure in a large animal model: a stereological study.

Respir Res. 2018 Dec 4;19(1):238. doi: 10.1186/s12931-018-0942-5.

 

Salman J, Grannas G, Ius F, Sommer W, Siemeni T, Avsar M, Kuehn C, Boethig D, Fleissner F, Bobylev D, Gottlieb J, Klempnauer J, Welte T, Haverich A, Tudorache I, Warnecke G, Lehner F (2018)

The liver-first approach for combined lung and liver transplantation.

Eur J Cardiothorac Surg. 2018 Dec 1;54(6):1122-1127. doi: 10.1093/ejcts/ezy217.

 

Danov O, Jiménez Delgado SM, Obernolte H, Seehase S, Dehmel S, Braubach P, Fieguth HG, Matschiner G, Fitzgerald M, Jonigk D, Knauf S, Pfennig O, Warnecke G, Wichmann J, Braun A, Sewald K (2018)

Human lung tissue provides highly relevant data about efficacy of new anti-asthmatic drugs.

PLoS One. 2018 Nov 30;13(11):e0207767. doi: 10.1371/journal.pone.0207767. eCollection 2018.

 

Salman J, Fleißner F, Naqizadah J, Avsar M, Shrestha M, Warnecke G, Ismail I, Rümke S, Cebotari S, Haverich A, Tudorache I (2018)

Minimally Invasive Mitral Valve Surgery in Re-Do Cases-The New Standard Procedure?

Thorac Cardiovasc Surg. 2018 Oct;66(7):545-551. doi: 10.1055/s-0038-1627478. Epub 2018 Feb 28.

 

Ius F, Verboom M, Sommer W, Poyanmehr R, Knoefel AK, Salman J, Kuehn C, Avsar M, Siemeni T, Erdfelder C, Hallensleben M, Boethig D, Schwerk N, Mueller C, Welte T, Falk C, Haverich A, Tudorache I, Warnecke G (2018)

Preemptive treatment of early donor-specific antibodies with IgA- and IgM-enriched intravenous human immunoglobulins in lung transplantation.

Am J Transplant. 2018 Sep;18(9):2295-2304. doi: 10.1111/ajt.14912. Epub 2018 Jun 3.

 

Ius F, Natanov R, Salman J, Kuehn C, Sommer W, Avsar M, Siemeni T, Bobylev D, Poyanmehr R, Boethig D, Optenhoefel J, Schwerk N, Haverich A, Warnecke G, Tudorache I (2018)

Extracorporeal membrane oxygenation as a bridge to lung transplantation may not impact overall mortality risk after transplantation: results from a 7-year single-centre experience.

Eur J Cardiothorac Surg. 2018 Aug 1;54(2):334-340. doi: 10.1093/ejcts/ezy036.

 

Ius F, Tudorache I, Warnecke G (2018)

Extracorporeal support, during and after lung transplantation: the history of an idea.

J Thorac Dis. 2018 Aug;10(8):5131-5148. doi: 10.21037/jtd.2018.07.43. Review.

 

Salman J, Jansson K, Siemeni T, Sommer W, Knoefel AK, Ahrens L, Nakagiri T, Ius F, Tudorache I, Kruse B, Thissen S, Jonigk D, Strüber M, Haverich A, Warnecke G, Avsar M (2018)

Role for primary immunosuppression with everolimus after pulmonary transplantation.

Transpl Immunol. 2018 Aug;49:12-19. doi: 10.1016/j.trim.2018.03.005. Epub 2018 Mar 26. No abstract available.

 

Neuhaus V, Danov O, Konzok S, Obernolte H, Dehmel S, Braubach P, Jonigk D, Fieguth HG, Zardo P, Warnecke G, Martin C, Braun A, Sewald K (2018)

Assessment of the Cytotoxic and Immunomodulatory Effects of Substances in Human Precision-cut Lung Slices.

J Vis Exp. 2018 May 9;(135). doi: 10.3791/57042.

 

Bobylev D, Salman J, Sommer W, Ius F, Siemeni T, Avsar M, Kühn C, Niehaus A, Gottlieb J, Haverich A, Tudorache I, Warnecke G (2018)

Single lung transplantation from a donor 8 months after double lung transplantation.

Am J Transplant. 2018 May;18(5):1275-1277. doi: 10.1111/ajt.14644. Epub 2018 Feb 2.

 

Warnecke G, Van Raemdonck D, Smith MA, Massard G, Kukreja J, Rea F, Loor G, De Robertis F, Nagendran J, Dhital KK, Moradiellos Díez FJ, Knosalla C, Bermudez CA, Tsui S, McCurry K, Wang IW, Deuse T, Lesèche G, Thomas P, Tudorache I, Kühn C, Avsar M, Wiegmann B, Sommer W, Neyrinck A, Schiavon M, Calabrese F, Santelmo N, Olland A, Falcoz PE, Simon AR, Varela A, Madsen JC, Hertz M, Haverich A, Ardehali A (2018)

Normothermic ex-vivo preservation with the portable Organ Care System Lung device for bilateral lung transplantation (INSPIRE): a randomised, open-label, non-inferiority, phase 3 study.

Lancet Respir Med. 2018 May;6(5):357-367. doi: 10.1016/S2213-2600(18)30136-X. Epub 2018 Apr 9. Erratum in: Lancet Respir Med. 2018 Jun;6(6):e27.

 

Fleissner F, Haverich A, Warnecke G (2018)

PCI Strategies in Acute Myocardial Infarction with Cardiogenic Shock.

N Engl J Med. 2018 Apr 5;378(14):1358-9. doi: 10.1056/NEJMc1802622. No abstract available.

 

Sommer W, Ius F, Kühn C, Avsar M, Salman J, Siemeni T, Müller C, Schwerk N, Greer M, Gottlieb J, Welte T, Haverich A, Tudorache I, Warnecke G (2018)

Technique and Outcomes of Less Invasive Lung Retransplantation.

Transplantation. 2018 Mar;102(3):530-537. doi: 10.1097/TP.0000000000001905.

 

Ceulemans LJ, Vos R, Neyrinck A, Pirenne J, Warnecke G, Van Raemdonck D (2018)

Liver-first versus lung-first: a new dilemma in combined organ transplantation.

Transpl Int. 2018 Feb;31(2):230-231. doi: 10.1111/tri.13099. Epub 2017 Dec 13. No abstract available.

 

Nyilas S, Carlens J, Price T, Singer F, Müller C, Hansen G, Warnecke G, Latzin P, Schwerk N (2018)

Multiple breath washout in pediatric patients after lung transplantation.

Am J Transplant. 2018 Jan;18(1):145-153. doi: 10.1111/ajt.14432. Epub 2017 Aug 21.

 

Madrahimov N, Boyle EC, Gueler F, Goecke T, Knöfel AK, Irkha V, Maegel L, Höffler K, Natanov R, Ismail I, Maus U, Kühn C, Warnecke G, Shrestha ML, Cebotari S, Haverich A (2018)

Novel mouse model of cardiopulmonary bypass.

Eur J Cardiothorac Surg. 2018 Jan 1;53(1):186-193. doi: 10.1093/ejcts/ezx237.

 

Peperhove M, Vo Chieu VD, Jang MS, Gutberlet M, Hartung D, Tewes S, Warnecke G, Fegbeutel C, Haverich A, Gwinner W, Lehner F, Bräsen JH, Haller H, Wacker F, Gueler F, Hueper K (2018)

Assessment of acute kidney injury with T1 mapping MRI following solid organ transplantation.

Eur Radiol. 2018 Jan;28(1):44-50. doi: 10.1007/s00330-017-4943-4. Epub 2017 Jul 14.

 

2017

Ackermann M, Gaumann A, Mentzer SJ, Hinrichs JB, Warnecke G, Hoeper MM, Braubach P, Kuehnel M, Maegel L, Jonigk D (2017)

Plexiform Vasculopathy in Chronic Thromboembolic Pulmonary Hypertension.

Am J Respir Crit Care Med. 2017 Oct 15;196(8):e48-e51. doi: 10.1164/rccm.201703-0591IM. No abstract available.

 

Hanke JS, Rojas SV, Cvitkovic T, Wiegmann B, Horke A, Warnecke G, Haverich A, Schmitto JD (2017)

First results of HeartWare left ventricular assist device implantation with tunnelling of the outflow graft through the transverse sinus.

Interact Cardiovasc Thorac Surg. 2017 Oct 1;25(4):503-508. doi: 10.1093/icvts/ivx124.

 

Madrahimov N, Natanov R, Boyle EC, Goecke T, Knöfel AK, Irkha V, Solovieva A, Höffler K, Maus U, Kühn C, Ismail I, Warnecke G, Shrestha ML, Cebotari S, Haverich A (2017)

Cardiopulmonary Bypass in a Mouse Model: A Novel Approach.

J Vis Exp. 2017 Sep 22;(127). doi: 10.3791/56017.

 

Dettmer S, Shin HO, Vogel-Claussen J, Westphal M, Haverich A, Warnecke G, Welte T, Wacker F, Gottlieb J, Suhling H (2017)

CT at onset of chronic lung allograft dysfunction in lung transplant patients predicts development of the restrictive phenotype and survival.

Eur J Radiol. 2017 Sep;94:78-84. doi: 10.1016/j.ejrad.2017.06.008. Epub 2017 Jun 15.

 

Ius F, Schulz J, Roumieh M, Fleissner F, Ismail I, Tudorache I, Warnecke G, Martens A, Shrestha M, Boethig D, Haverich A, Cebotari S (2017)

Long-term results of the Mitroflow aortic pericardial bioprosthesis in over 800 patients: limited durability and mechanisms of dysfunction.

Eur J Cardiothorac Surg. 2017 Aug 1;52(2):264-271. doi: 10.1093/ejcts/ezx161.

 

Salman J, Ius F, Sommer W, Siemeni T, Kuehn C, Avsar M, Boethig D, Molitoris U, Bara C, Gottlieb J, Welte T, Haverich A, Hoeper MM, Warnecke G, Tudorache I(2017)

Mid-term results of bilateral lung transplant with postoperatively extended intraoperative extracorporeal membrane oxygenation for severe pulmonary hypertension.

Eur J Cardiothorac Surg. 2017 Jul 1;52(1):163-170. doi: 10.1093/ejcts/ezx047.

 

Hanke JS, Dogan G, Rojas SV, Zoch A, Feldmann C, Deniz E, Avsar M, Warnecke G, Haverich A, Schmitto JD (2017)

First experiences with HeartMate 3 follow-up and adverse events.

J Thorac Cardiovasc Surg. 2017 Jul;154(1):173-178. doi: 10.1016/j.jtcvs.2017.01.045. Epub 2017 Feb 9.

 

Jansson K, Dreckmann K, Sommer W, Avsar M, Salman J, Siemeni T, Knöfel AK, Pauksch L, Gottlieb J, Frühauf J, Werner M, Jonigk D, Strüber M, Haverich A, Warnecke G (2017)

Splenocyte Infusion and Whole-Body Irradiation for Induction of Peripheral Tolerance in Porcine Lung Transplantation: Modifications of the Preconditioning Regime for Improved Clinical Feasibility.

Transplant Direct. 2017 Jun 6;3(7):e170. doi: 10.1097/TXD.0000000000000689. eCollection 2017 Jul.

 

Salman J, Ius F, Knoefel AK, Sommer W, Siemeni T, Kuehn C, Tudorache I, Avsar M, Nakagiri T, Preissler G, Hatz R, Greer M, Welte T, Haverich A, Warnecke G (2017)

Association of Higher CD4+ CD25high CD127low , FoxP3+ , and IL-2+ T Cell Frequencies Early After Lung Transplantation With Less Chronic Lung Allograft Dysfunction at Two Years.

Am J Transplant. 2017 Jun;17(6):1637-1648. doi: 10.1111/ajt.14148. Epub 2017 Jan 24.

 

Neuhaus V, Schaudien D, Golovina T, Temann UA, Thompson C, Lippmann T, Bersch C, Pfennig O, Jonigk D, Braubach P, Fieguth HG, Warnecke G, Yusibov V, Sewald K, Braun A (2017)

Assessment of long-term cultivated human precision-cut lung slices as an ex vivo system for evaluation of chronic cytotoxicity and functionality.

J Occup Med Toxicol. 2017 May 26;12:13. doi: 10.1186/s12995-017-0158-5. eCollection 2017.

 

Sommer W, Buechler G, Jansson K, Avsar M, Knöfel AK, Salman J, Hoeffler K, Siemeni T, Gottlieb J, Karstens JH, Jonigk D, Reising A, Haverich A, Strüber M, Warnecke G (2017)

Irradiation before and donor splenocyte infusion immediately after transplantation induce tolerance to lung, but not heart allografts in miniature swine.

Transpl Int. 2017 Apr;30(4):420-431. doi: 10.1111/tri.12916. Epub 2017 Mar 5.

 

Sommer W, Hallensleben M, Ius F, Kühn C, Tudorache I, Avsar M, Salman J, Siemeni T, Greer M, Gottlieb J, Boethig D, Blasczyk R, Haverich A, Warnecke G (2017)

Repeated human leukocyte antigen mismatches in lung re-transplantation.

Transpl Immunol. 2017 Feb;40:1-7. doi: 10.1016/j.trim.2016.12.001. Epub 2016 Dec 5.

 

Ruttens D, Verleden SE, Bijnens EM, Winckelmans E, Gottlieb J, Warnecke G, Meloni F, Morosini M, Van Der Bij W, Verschuuren EA, Sommerwerck U, Weinreich G, Kamler M, Roman A, Gomez-Olles S, Berastegui C, Benden C, Holm AM, Iversen M, Schultz HH, Luijk B, Oudijk EJ, Kwakkel-van Erp JM, Jaksch P, Klepetko W, Kneidinger N, Neurohr C, Corris P, Fisher AJ, Lordan J, Meachery G, Piloni D, Vandermeulen E, Bellon H, Hoffmann B, Vienneau D, Hoek G, de Hoogh K, Nemery B, Verleden GM, Vos R, Nawrot TS, Vanaudenaerde BM (2017)

An association of particulate air pollution and traffic exposure with mortality after lung transplantation in Europe.

Eur Respir J. 2017 Jan 18;49(1). pii: 1600484. doi: 10.1183/13993003.00484-2016. Print 2017 Jan.

 

2016

Jonigk D, Rath B, Borchert P, Braubach P, Maegel L, Izykowski N, Warnecke G, Sommer W, Kreipe H, Blach R, Anklamm A, Haverich A, Eder M, Stadler M, Welte T, Gottlieb J, Kuehnel M, Laenger F (2016)

Comparative analysis of morphological and molecular motifs in bronchiolitis obliterans and alveolar fibroelastosis after lung and stem cell transplantation.

J Pathol Clin Res. 2016 Dec 10;3(1):17-28. doi: 10.1002/cjp2.60. eCollection 2017 Jan.

 

Bobylev D, Warnecke G, Dennhardt N, Horke A (2016)

Giant pleuropulmonary blastoma.

Eur J Cardiothorac Surg. 2016 Dec;50(6):1215-1216. doi: 10.1093/ejcts/ezw217. Epub 2016 Jun 23. No abstract available.

 

Siemeni T, Knöfel AK, Madrahimov N, Sommer W, Avsar M, Salman J, Ius F, Frank N, Büchler G, Jonigk D, Jansson K, Maus U, Tudorache I, Falk CS, Haverich A, Warnecke G (2016)

In Vivo Development of Transplant Arteriosclerosis in Humanized Mice Reflects Alloantigen Recognition and Peripheral Treg Phenotype of Lung Transplant Recipients.

Am J Transplant. 2016 Nov;16(11):3150-3162. doi: 10.1111/ajt.13905. Epub 2016 Jul 29.

 

Strueber M, Warnecke G, Fuge J, Simon AR, Zhang R, Welte T, Haverich A, Gottlieb J (2016)

Everolimus Versus Mycophenolate Mofetil De Novo After Lung Transplantation: A Prospective, Randomized, Open-Label Trial.

Am J Transplant. 2016 Nov;16(11):3171-3180. doi: 10.1111/ajt.13835. Epub 2016 Jun 15.

 

Vogl M, Warnecke G, Haverich A, Gottlieb J, Welte T, Hatz R, Hunger M, Leidl R, Lingner H, Behr J, Winter H, Schramm R, Zwissler B, Hagl C, Strobl N, Jaeger C, Preissler G (2016)

Lung transplantation in the spotlight: Reasons for high-cost procedures.

J Heart Lung Transplant. 2016 Oct;35(10):1227-1236. doi: 10.1016/j.healun.2016.05.024. Epub 2016 Jun 7.

 

Warnecke G (2016)

Ex Vivo Treatment.

Transplantation. 2016 Jul;100(7):1400-1. doi: 10.1097/TP.0000000000001182. No abstract available.

 

Izykowski N, Kuehnel M, Hussein K, Mitschke K, Gunn M, Janciauskiene S, Haverich A, Warnecke G, Laenger F, Maus U, Jonigk D (2016)

Organizing pneumonia in mice and men.

J Transl Med. 2016 Jun 10;14(1):169. doi: 10.1186/s12967-016-0933-6.

 

Rademacher J, Ringshausen FC, Suhling H, Fuge J, Marsch G, Warnecke G, Haverich A, Welte T, Gottlieb J (2016)

Lung transplantation for non-cystic fibrosis bronchiectasis.

Respir Med. 2016 Jun;115:60-5. doi: 10.1016/j.rmed.2016.04.007. Epub 2016 Apr 20.

 

Hadem J, Gottlieb J, Seifert D, Fegbeutel C, Sommer W, Greer M, Wiesner O, Kielstein JT, Schneider AS, Ius F, Fuge J, Kühn C, Tudorache I, Haverich A, Welte T, Warnecke G, Hoeper MM (2016)

Prolonged Mechanical Ventilation After Lung Transplantation-A Single-Center Study.

Am J Transplant. 2016 May;16(5):1579-87. doi: 10.1111/ajt.13632. Epub 2016 Feb 26.

 

Avsar M, Jansson K, Sommer W, Kruse B, Thissen S, Dreckmann K, Knoefel AK, Salman J, Hafer C, Hecker J, Buechler G, Karstens JH, Jonigk D, Länger F, Kaever V, Falk CS, Hewicker-Trautwein M, Ungefroren H, Haverich A, Strüber M, Warnecke G (2016)

Augmentation of Transient Donor Cell Chimerism and Alloantigen-Specific Regulation of Lung Transplants in Miniature Swine.

Am J Transplant. 2016 May;16(5):1371-82. doi: 10.1111/ajt.13629. Epub 2016 Feb 22.

 

Hansmann G, Apitz C, Abdul-Khaliq H, Alastalo TP, Beerbaum P, Bonnet D, Dubowy KO, Gorenflo M, Hager A, Hilgendorff A, Kaestner M, Koestenberger M, Koskenvuo JW, Kozlik-Feldmann R, Kuehne T, Lammers AE, Latus H, Michel-Behnke I, Miera O, Moledina S, Muthurangu V, Pattathu J, Schranz D, Warnecke G, Zartner P (2016)

Executive summary. Expert consensus statement on the diagnosis and treatment of paediatric pulmonary hypertension. The European Paediatric Pulmonary Vascular Disease Network, endorsed by ISHLT and DGPK.

Heart. 2016 May;102 Suppl 2:ii86-100. doi: 10.1136/heartjnl-2015-309132.

 

Kaestner M, Schranz D, Warnecke G, Apitz C, Hansmann G, Miera O (2016)

Pulmonary hypertension in the intensive care unit. Expert consensus statement on the diagnosis and treatment of paediatric pulmonary hypertension. The European Paediatric Pulmonary Vascular Disease Network, endorsed by ISHLT and DGPK.

Heart. 2016 May;102 Suppl 2:ii57-66. doi: 10.1136/heartjnl-2015-307774.

 

Pils MC, Dreckmann K, Jansson K, Glage S, Held N, Sommer W, Länger F, Avsar M, Warnecke G, Bleich A (2016)

Mortality Due to Porcine Reproductive and Respiratory Syndrome Virus in Immunocompromised Göttingen Minipigs (Sus scrofa domestica).

Comp Med. 2016;66(5):392-398.

 

Gohrbandt B, Warnecke G, Fischer S, Simon AR, Gottlieb J, Niehaus A, Böthig D, Haverich A, Strueber M (2016)

Retrograde in situ versus antegrade pulmonary preservation in clinical lung transplantation: a single-centre experience.

Eur J Cardiothorac Surg. 2016 Jan;49(1):55-62. doi: 10.1093/ejcts/ezv108. Epub 2015 Apr 16.

 

Ius F, Sommer W, Tudorache I, Avsar M, Siemeni T, Salman J, Molitoris U, Gras C, Juettner B, Puntigam J, Optenhoefel J, Greer M, Schwerk N, Gottlieb J, Welte T, Hoeper MM, Haverich A, Kuehn C, Warnecke G (2016)

Five-year experience with intraoperative extracorporeal membrane oxygenation in lung transplantation: Indications and midterm results.

J Heart Lung Transplant. 2016 Jan;35(1):49-58. doi: 10.1016/j.healun.2015.08.016. Epub 2015 Sep 5.

 

Becker S, Steinmeyer J, Avsar M, Höffler K, Salman J, Haverich A, Warnecke G, Ochs M, Schnapper A (2016)

Evaluating acellular versus cellular perfusate composition during prolonged ex vivo lung perfusion after initial cold ischaemia for 24 hours.

Transpl Int. 2016 Jan;29(1):88-97. doi: 10.1111/tri.12649. Epub 2015 Aug 27.

 

2015

Jonigk D, Izykowski N, Rische J, Braubach P, Kühnel M, Warnecke G, Lippmann T, Kreipe H, Haverich A, Welte T, Gottlieb J, Laenger F (2015)

Molecular Profiling in Lung Biopsies of Human Pulmonary Allografts to Predict Chronic Lung Allograft Dysfunction.

Am J Pathol. 2015 Dec;185(12):3178-88. doi: 10.1016/j.ajpath.2015.08.016. Epub 2015 Oct 23.

 

Kellner M, Wehling J, Warnecke G, Heidrich M, Izykowski N, Vogel-Claussen J, Lorbeer RA, Antonopoulos G, Janciauskiene S, Grothausmann R, Knudsen L, Ripken T, Meyer H, Kreipe H, Ochs M, Jonigk D, Kühnel MP (2015)

Correlating 3D morphology with molecular pathology: fibrotic remodelling in human lung biopsies.

Thorax. 2015 Dec;70(12):1197-8. doi: 10.1136/thoraxjnl-2015-207131. Epub 2015 Jun 24.

 

Harms A, Fuehner T, Warnecke G, Haverich A, Gottlieb J, Trummer A (2015)

Epithelial and Erythrocyte Microvesicles From Bronchoalveolar Lavage Fluid Are Elevated and Associated With Outcome in Chronic Lung Allograft Dysfunction.

Transplantation. 2015 Nov;99(11):2394-400. doi: 10.1097/TP.0000000000000881.

 

Sommer W, Ius F, Salman J, Avsar M, Tudorache I, Kühn C, Wiegmann B, Marsch G, Kaufeld T, Zinne N, Fuehner T, Greer M, Gottlieb J, Boethig D, Haverich A, Welte T, Warnecke G (2015)

Survival and spirometry outcomes after lung transplantation from donors aged 70 years and older.

J Heart Lung Transplant. 2015 Oct;34(10):1325-33. doi: 10.1016/j.healun.2015.06.002. Epub 2015 Jun 10.

 

Kayacelebi AA, Knöfel AK, Beckmann B, Hanff E, Warnecke G, Tsikas D (2015)

Measurement of unlabeled and stable isotope-labeled homoarginine, arginine and their metabolites in biological samples by GC-MS and GC-MS/MS.

Amino Acids. 2015 Sep;47(9):2023-34. doi: 10.1007/s00726-015-1984-3. Epub 2015 May 10.

 

Janssen H, Wagner CS, Demmer P, Callies S, Sölter G, Loghmani-khouzani H, Hu N, Schuett H, Tietge UJ, Warnecke G, Larmann J, Theilmeier G (2015)

Acute perioperative-stress-induced increase of atherosclerotic plaque volume and vulnerability to rupture in apolipoprotein-E-deficient mice is amenable to statin treatment and IL-6 inhibition.

Dis Model Mech. 2015 Sep;8(9):1071-80. doi: 10.1242/dmm.018713. Epub 2015 Jun 18.

 

Gohrbandt B, Simon AR, Warnecke G, Fischer S, Hagl C, Niehaus A, Gottlieb J, Welte T, Haverich A, Strueber M (2015)

Lung Preservation With Perfadex or Celsior in Clinical Transplantation: A Retrospective Single-Center Analysis of Outcomes.

Transplantation. 2015 Sep;99(9):1933-9. doi: 10.1097/TP.0000000000000578.

 

Verleden SE, Todd JL, Sato M, Palmer SM, Martinu T, Pavlisko EN, Vos R, Neyrinck A, Van Raemdonck D, Saito T, Oishi H, Keshavjee S, Greer M, Warnecke G, Gottlieb J, Haverich A (2015)

Impact of CLAD Phenotype on Survival After Lung Retransplantation: A Multicenter Study.

Am J Transplant. 2015 Aug;15(8):2223-30. doi: 10.1111/ajt.13281. Epub 2015 Apr 30.

 

Lam E, Ramke M, Warnecke G, Schrepfer S, Kopfnagel V, Dobner T, Heim A (2015)

Effective Apical Infection of Differentiated Human Bronchial Epithelial Cells and Induction of Proinflammatory Chemokines by the Highly Pneumotropic Human Adenovirus Type 14p1.

PLoS One. 2015 Jul 13;10(7):e0131201. doi: 10.1371/journal.pone.0131201. eCollection 2015.

 

Renne J, Lauermann P, Hinrichs JB, Schönfeld C, Sorrentino S, Gutberlet M, Jakob P, Haverich A, Warnecke G, Welte T, Wacker FK, Gottlieb J, Vogel-Claussen J (2015)

Chronic Lung Allograft Dysfunction: Oxygen-enhanced T1-Mapping MR Imaging of the Lung.

Radiology. 2015 Jul;276(1):266-73. doi: 10.1148/radiol.15141486. Epub 2015 Mar 27.

 

Ius F, Sommer W, Tudorache I, Avsar M, Siemeni T, Salman J, Puntigam J, Optenhoefel J, Greer M, Welte T, Wiesner O, Haverich A, Hoeper M, Kuehn C, Warnecke G (2015)

Veno-veno-arterial extracorporeal membrane oxygenation for respiratory failure with severe haemodynamic impairment: technique and early outcomes.

Interact Cardiovasc Thorac Surg. 2015 Jun;20(6):761-7. doi: 10.1093/icvts/ivv035. Epub 2015 Mar 3.

 

Sommer W, Marsch G, Kaufeld T, Röntgen P, Beutel G, Tongers J, Warnecke G, Tudorache I, Schieffer B, Haverich A, Kühn C (2015)

Cardiac awake extracorporeal life support-bridge to decision?

Artif Organs. 2015 May;39(5):400-8. doi: 10.1111/aor.12396. Epub 2015 Jan 16.

 

Fleissner F, Warnecke G, Cebotari S, Rustum S, Haverich A, Ismail I (2015)

Coronary artery bypass grafting in young patients--insights into a distinct entity.

J Cardiothorac Surg. 2015 May 1;10:65. doi: 10.1186/s13019-015-0266-1.

 

Kugler C, Einhorn I, Gottlieb J, Warnecke G, Schwarz A, Barg-Hock H, Bara C, Haller H, Haverich A (2015)

Postoperative weight gain during the first year after kidney, liver, heart, and lung transplant: a prospective study.

Prog Transplant. 2015 Mar;25(1):49-55. doi: 10.7182/pit2015668.

 

Sommer W, Knöfel AK, Madrahimov N, Avsar M, Jonigk D, Salman J, Dreckmann K, Jansson K, Salguero G, Maus UA, Welte T, Haverich A, Warnecke G (2015)

Allogeneic CD4+CD25high T cells regulate obliterative bronchiolitis of heterotopic bronchus allografts in both porcinized and humanized mouse models.

Transplantation. 2015 Mar;99(3):482-91. doi: 10.1097/TP.0000000000000632.

 

Tudorache I, Sommer W, Kühn C, Wiesner O, Hadem J, Fühner T, Ius F, Avsar M, Schwerk N, Böthig D, Gottlieb J, Welte T, Bara C, Haverich A, Hoeper MM, Warnecke G (2015)

Lung transplantation for severe pulmonary hypertension--awake extracorporeal membrane oxygenation for postoperative left ventricular remodelling.

Transplantation. 2015 Feb;99(2):451-8. doi: 10.1097/TP.0000000000000348.

 

Ius F, Sommer W, Tudorache I, Kühn C, Avsar M, Siemeni T, Salman J, Hallensleben M, Kieneke D, Greer M, Gottlieb J, Kielstein JT, Boethig D, Welte T, Haverich A, Warnecke G (2015)

Preemptive treatment with therapeutic plasma exchange and rituximab for early donor-specific antibodies after lung transplantation.

J Heart Lung Transplant. 2015 Jan;34(1):50-58. doi: 10.1016/j.healun.2014.09.019. Epub 2014 Sep 28.

 

Sommer W, Knöfel AK, Izykowski N, Oldhafer F, Avsar M, Jonigk D, Warnecke G, Haverich A (2015)

Physical exercise reduces transplant arteriosclerosis in a mouse aorta transplantation model.

J Thorac Cardiovasc Surg. 2015 Jan;149(1):330-7. doi: 10.1016/j.jtcvs.2014.10.029. Epub 2014 Oct 15.

 

2014

Hinrichs JB, Renne J, Schoenfeld C, Gutberlet M, Haverich A, Warnecke G, Welte T, Wacker F, Gottlieb J, Vogel-Claussen J (2014)

Cardiac mass and function decrease in bronchiolitis obliterans syndrome after lung transplantation: relationship to physical activity?

PLoS One. 2014 Dec 5;9(12):e114001. doi: 10.1371/journal.pone.0114001. eCollection 2014. Erratum in: PLoS One. 2015;10(3):e0119999.

 

Ius F, Sommer W, Tudorache I, Kühn C, Avsar M, Siemeni T, Salman J, Hallensleben M, Kieneke D, Greer M, Gottlieb J, Haverich A, Warnecke G (2014)

Early donor-specific antibodies in lung transplantation: risk factors and impact on survival.

J Heart Lung Transplant. 2014 Dec;33(12):1255-63. doi: 10.1016/j.healun.2014.06.015. Epub 2014 Jun 26.

 

Bobylev D, Sommer W, Avsar M, Horke A, Haverich A, Warnecke G (2014)

Aortopulmonary window: a rare untreated adult case.

Heart Lung Circ. 2014 Oct;23(10):e235-6. doi: 10.1016/j.hlc.2014.06.006. Epub 2014 Jun 26. No abstract available.

 

Noyan F, Lee YS, Zimmermann K, Hardtke-Wolenski M, Taubert R, Warnecke G, Knoefel AK, Schulde E, Olek S, Manns MP, Jaeckel E (2014)

Isolation of human antigen-specific regulatory T cells with high suppressive function.

Eur J Immunol. 2014 Sep;44(9):2592-602. doi: 10.1002/eji.201344381. Epub 2014 Aug 8.

 

Timrott K, Vondran FW, Kleine M, Warnecke G, Haverich A, Lehner F, Klempnauer J (2014)

The impact of abdominal complications on the outcome after thoracic transplantation--a single center experience.

Langenbecks Arch Surg. 2014 Aug;399(6):789-93. doi: 10.1007/s00423-014-1193-7. Epub 2014 Apr 11.

 

Sommer W, Tudorache I, Kühn C, Avsar M, Salman J, Ius F, Gras C, Weber P, Welte T, Gottlieb J, Haverich A, Warnecke G (2014)

C1-esterase-inhibitor for primary graft dysfunction in lung transplantation.

Transplantation. 2014 Jun 15;97(11):1185-91. doi: 10.1097/TP.0000000000000034.

 

Rademacher J, Suhling H, Greer M, Haverich A, Welte T, Warnecke G, Gottlieb J (2014)

Safety and efficacy of outpatient bronchoscopy in lung transplant recipients - a single centre analysis of 3,197 procedures.

Transplant Res. 2014 May 27;3:11. doi: 10.1186/2047-1440-3-11. eCollection 2014.

 

Dettmer S, Peters L, de Wall C, Schaefer-Prokop C, Schmidt M, Warnecke G, Gottlieb J, Wacker F, Shin HO (2014)

Bronchial wall measurements in patients after lung transplantation: evaluation of the diagnostic value for the diagnosis of bronchiolitis obliterans syndrome.

PLoS One. 2014 Apr 8;9(4):e93783. doi: 10.1371/journal.pone.0093783. eCollection 2014.

 

Suhling H, Rademacher J, Zinowsky I, Fuge J, Greer M, Warnecke G, Smits JM, Bertram A, Haverich A, Welte T, Gottlieb J (2014)

Conventional vs. tablet computer-based patient education following lung transplantation--a randomized controlled trial.

PLoS One. 2014 Mar 7;9(6):e90828. doi: 10.1371/journal.pone.0090828. eCollection 2014.

 

2013

Hoeper MM, Wiesner O, Hadem J, Wahl O, Suhling H, Duesberg C, Sommer W, Warnecke G, Greer M, Boenisch O, Busch M, Kielstein JT, Schneider A, Haverich A, Welte T, Kühn C (2013)

Extracorporeal membrane oxygenation instead of invasive mechanical ventilation in patients with acute respiratory distress syndrome.

Intensive Care Med. 2013 Nov;39(11):2056-7. doi: 10.1007/s00134-013-3052-3. Epub 2013 Aug 7. No abstract available.

 

Sommer W, Kühn C, Tudorache I, Avsar M, Gottlieb J, Boethig D, Haverich A, Warnecke G (2013)

Extended criteria donor lungs and clinical outcome: results of an alternative allocation algorithm.

J Heart Lung Transplant. 2013 Nov;32(11):1065-72. doi: 10.1016/j.healun.2013.06.021. Epub 2013 Aug 13.

 

Bertram A, Haenel SS, Hadem J, Hoeper MM, Gottlieb J, Warnecke G, Kaschinski S, Hafer C, Kühn-Velten WN, Günther D, Kielstein JT (2013)

Tissue concentration of paraquat on day 32 after intoxication and failed bridge to transplantation by extracorporeal membrane oxygenation therapy.

BMC Pharmacol Toxicol. 2013 Sep 6;14:45. doi: 10.1186/2050-6511-14-45.

 

Kugler C, Gottlieb J, Warnecke G, Schwarz A, Weissenborn K, Barg-Hock H, Bara C, Einhorn I, Haverich A, Haller H (2013)

Health-related quality of life after solid organ transplantation: a prospective, multiorgan cohort study.

Transplantation. 2013 Aug 15;96(3):316-23. doi: 10.1097/TP.0b013e31829853eb.

 

Neuhaus V, Schwarz K, Klee A, Seehase S, Förster C, Pfennig O, Jonigk D, Fieguth HG, Koch W, Warnecke G, Yusibov V, Sewald K, Braun A (2013)

Functional testing of an inhalable nanoparticle based influenza vaccine using a human precision cut lung slice technique.

PLoS One. 2013 Aug 13;8(8):e71728. doi: 10.1371/journal.pone.0071728. eCollection 2013.

 

Gohrbandt B, Avsar M, Warnecke G, Sommer SP, Haverich A, Strueber M (2013)

Initial topical cooling followed by backtable Celsior flush perfusion provides excellent early graft function in porcine single lung transplantation after 24 hours of cold ischemia.

J Heart Lung Transplant. 2013 Aug;32(8):832-8. doi: 10.1016/j.healun.2013.06.005.

 

Schmidt F, Sasse M, Boehne M, Mueller C, Bertram H, Kuehn C, Warnecke G, Ono M, Seidemann K, Jack T, Koeditz H (2013)

Concept of "awake venovenous extracorporeal membrane oxygenation" in pediatric patients awaiting lung transplantation.

Pediatr Transplant. 2013 May;17(3):224-30. doi: 10.1111/petr.12001. Epub 2012 Oct 11.

 

Suhling H, de Wall C, Rademacher J, Greer M, Boemke A, Dettmer S, Haverich A, Warnecke G, Welte T, Gottlieb J (2013)

Low exercise tolerance correlates with reduced inspiratory capacity and respiratory muscle function in recipients with advanced chronic lung allograft dysfunction.

Transplantation. 2013 Apr 27;95(8):1045-50. doi: 10.1097/TP.0b013e31828555d0.

 

Greer M, Dierich M, De Wall C, Suhling H, Rademacher J, Welte T, Haverich A, Warnecke G, Ivanyi P, Buchholz S, Gottlieb J, Fuehner T (2013)

Phenotyping established chronic lung allograft dysfunction predicts extracorporeal photopheresis response in lung transplant patients.

Am J Transplant. 2013 Apr;13(4):911-918. doi: 10.1111/ajt.12155. Epub 2013 Feb 13.

 

Dierich M, Tecklenburg A, Fuehner T, Tegtbur U, Welte T, Haverich A, Warnecke G, Gottlieb J (2013)

The influence of clinical course after lung transplantation on rehabilitation success.

Transpl Int. 2013 Mar;26(3):322-30. doi: 10.1111/tri.12048. Epub 2013 Jan 7.

 

Schlischewsky E, Fuehner T, Warnecke G, Welte T, Haverich A, Ganzenmueller T, Heim A, Gottlieb J (2013)

Clinical significance of quantitative cytomegalovirus detection in bronchoalveolar lavage fluid in lung transplant recipients.

Transpl Infect Dis. 2013 Feb;15(1):60-9. doi: 10.1111/tid.12015. Epub 2012 Oct 2.

 

2012

Ius F, Kuehn C, Tudorache I, Sommer W, Avsar M, Boethig D, Fuehner T, Gottlieb J, Hoeper M, Haverich A, Warnecke G (2012)

Lung transplantation on cardiopulmonary support: venoarterial extracorporeal membrane oxygenation outperformed cardiopulmonary bypass.

J Thorac Cardiovasc Surg. 2012 Dec;144(6):1510-6. doi: 10.1016/j.jtcvs.2012.07.095. Epub 2012 Aug 31.

 

Warnecke G, Moradiellos J, Tudorache I, Kühn C, Avsar M, Wiegmann B, Sommer W, Ius F, Kunze C, Gottlieb J, Varela A, Haverich A (2012)

Normothermic perfusion of donor lungs for preservation and assessment with the Organ Care System Lung before bilateral transplantation: a pilot study of 12 patients.

Lancet. 2012 Nov 24;380(9856):1851-8. doi: 10.1016/S0140-6736(12)61344-0. Epub 2012 Oct 10.

 

Warnecke G, Haverich A (2012)

Lung re-transplantation: review.

Curr Opin Organ Transplant. 2012 Oct;17(5):485-9. doi: 10.1097/MOT.0b013e328357d8ba. Review.

 

Gottlieb J, Warnecke G, Hadem J, Dierich M, Wiesner O, Fühner T, Strueber M, Haverich A, Welte T (2012)

Outcome of critically ill lung transplant candidates on invasive respiratory support.

Intensive Care Med. 2012 Jun;38(6):968-75. doi: 10.1007/s00134-012-2551-y. Epub 2012 Apr 14.

 

Fuehner T, Kuehn C, Hadem J, Wiesner O, Gottlieb J, Tudorache I, Olsson KM, Greer M, Sommer W, Welte T, Haverich A, Hoeper MM, Warnecke G (2012)

Extracorporeal membrane oxygenation in awake patients as bridge to lung transplantation.

Am J Respir Crit Care Med. 2012 Apr 1;185(7):763-8. doi: 10.1164/rccm.201109-1599OC. Epub 2012 Jan 20.

 

Nakagiri T, Warnecke G, Avsar M, Thissen S, Kruse B, Kühn C, Ziehme P, Knöfel AK, Madrahimov N, Okumura M, Sawa Y, Gottlieb J, Simon AR, Haverich A, Strüber M (2012)

Lung function early after lung transplantation is correlated with the frequency of regulatory T cells.

Surg Today. 2012 Feb;42(3):250-8. doi: 10.1007/s00595-011-0087-3. Epub 2011 Dec 17.

 

Suhling H, Dettmer S, Rademacher J, Greer M, Shin HO, Tudorache I, Kühn C, Haverich A, Welte T, Warnecke G, Gottlieb J (2012)

Spirometric obstructive lung function pattern early after lung transplantation.

Transplantation. 2012 Jan 27;93(2):230-5. doi: 10.1097/TP.0b013e31823dd670. Erratum in: Transplantation. 2012 Apr 27;93(8):e37. Mark, Greer [corrected to Greer, Mark].

 

2011

Lam E, Ramke M, Groos S, Warnecke G, Heim A (2011)

A differentiated porcine bronchial epithelial cell culture model for studying human adenovirus tropism and virulence.

J Virol Methods. 2011 Dec;178(1-2):117-23. doi: 10.1016/j.jviromet.2011.08.025. Epub 2011 Aug 31.

 

Salguero G, Sundarasetty BS, Borchers S, Wedekind D, Eiz-Vesper B, Velaga S, Jirmo AC, Behrens G, Warnecke G, Knöfel AK, Blasczyk R, Mischak-Weissinger E, Ganser A, Stripecke R (2011)

Preconditioning therapy with lentiviral vector-programmed dendritic cells accelerates the homeostatic expansion of antigen-reactive human T cells in NOD.Rag1-/-.IL-2rγc-/- mice.

Hum Gene Ther. 2011 Oct;22(10):1209-24. doi: 10.1089/hum.2010.215. Epub 2011 Jul 27.

 

Li Y, Gottlieb J, Ma D, Kuehn C, Strueber M, Welte T, Simon AR, Warnecke G, Haverich A (2011)

Graft-protective effects of the HMG-CoA reductase inhibitor pravastatin after lung transplantation--a propensity score analysis with 23 years of follow-up.

Transplantation. 2011 Aug 27;92(4):486-92. doi: 10.1097/TP.0b013e318225670d.

 

Bisdas T, Beutel G, Warnecke G, Hoeper MM, Kuehn C, Haverich A, Teebken OE (2011)

Vascular complications in patients undergoing femoral cannulation for extracorporeal membrane oxygenation support.

Ann Thorac Surg. 2011 Aug;92(2):626-31. doi: 10.1016/j.athoracsur.2011.02.018. Epub 2011 May 8.

 

Peterss S, Gratz KF, Khaladj N, Hagl C, Warnecke G, Fischer S, Haverich A (2011)

Lymphoscintigraphic localization of a high-output chylus leak after bilateral lung transplantation.

J Heart Lung Transplant. 2011 Apr;30(4):481-3. doi: 10.1016/j.healun.2010.10.017. Epub 2010 Dec 18.

 

Fuehner T, Dierich M, Duesberg C, DeWall C, Welte T, Haverich A, Warnecke G, Simon AR, Gottlieb J (2011)

Single-centre experience with oral ribavirin in lung transplant recipients with paramyxovirus infections.

Antivir Ther. 2011;16(5):733-40. doi: 10.3851/IMP1811.

 

2010

Fuehner T, Dierich M, Duesberg C, Wiesner O, Warnecke G, Welte T, Simon AR, Gottlieb J (2010)

Endoscopic indicators for obstructive airway complications after lung transplantation.

Transplantation. 2010 Dec 15;90(11):1210-4. doi: 10.1097/TP.0b013e3181fa945f.

 

Olsson KM, Simon A, Strueber M, Hadem J, Wiesner O, Gottlieb J, Fuehner T, Fischer S, Warnecke G, Kühn C, Haverich A, Welte T, Hoeper MM (2010)

Extracorporeal membrane oxygenation in nonintubated patients as bridge to lung transplantation.

Am J Transplant. 2010 Sep;10(9):2173-8. doi: 10.1111/j.1600-6143.2010.03192.x. Epub 2010 Jul 15.

 

Goerler H, Simon A, Warnecke G, Meyer AL, Kuehn C, Haverich A, Strueber M (2010)

Cardiac surgery late after heart transplantation: a safe and effective treatment option.

J Thorac Cardiovasc Surg. 2010 Aug;140(2):433-9. doi: 10.1016/j.jtcvs.2010.02.033. Epub 2010 Apr 9.

 

Warnecke G, Feng G, Goto R, Nadig SN, Francis R, Wood KJ, Bushell A (2010)

CD4+ regulatory T cells generated in vitro with IFN-{gamma} and allogeneic APC inhibit transplant arteriosclerosis.

Am J Pathol. 2010 Jul;177(1):464-72. doi: 10.2353/ajpath.2010.090292. Epub 2010 May 14.

 

2009

Kruse B, Thissen S, Warnecke G, Avsar M, Gottlieb J, Hohlfeld JM, Karstens JH, Kaever V, Länger F, Pabst B, Ungefroren H, Haverich A, Strüber M (2009)

Correlation of donor leukocyte chimerism with pulmonary allograft survival after immunosuppressive drug withdrawal in a porcine model.

Transplantation. 2009 May 27;87(10):1468-77. doi: 10.1097/TP.0b013e3181a3c4cb.

 

Strueber M, Hoeper MM, Fischer S, Cypel M, Warnecke G, Gottlieb J, Pierre A, Welte T, Haverich A, Simon AR, Keshavjee S (2009)

Bridge to thoracic organ transplantation in patients with pulmonary arterial hypertension using a pumpless lung assist device.

Am J Transplant. 2009 Apr;9(4):853-7. doi: 10.1111/j.1600-6143.2009.02549.x.

 

Görler H, Strüber M, Ballmann M, Müller C, Gottlieb J, Warnecke G, Gohrbandt B, Haverich A, Simon A (2009)

Lung and heart-lung transplantation in children and adolescents: a long-term single-center experience.

J Heart Lung Transplant. 2009 Mar;28(3):243-8. doi: 10.1016/j.healun.2008.12.012.

 

Warnecke G, Hutchinson JA, Riquelme P, Kruse B, Thissen S, Avsar M, Zehle G, Steinkamp T, Peters C, Baumann R, Gövert F, Ungefroren H, Länger F, Simon AR, Karstens JH, Kaever V, Haverich A, Fändrich F, Strüber M (2009)

Postoperative intravenous infusion of donor-derived transplant acceptance-inducing cells as an adjunct immunosuppressive therapy in a porcine pulmonary allograft model.

Transpl Int. 2009 Mar;22(3):332-41. doi: 10.1111/j.1432-2277.2008.00778.x. Epub 2008 Oct 21.

 

2008

Strüber M, Warnecke G, Hafer C, Goudeva L, Fegbeutel C, Fischer S, Gottlieb J, Avsar M, Simon AR, Haverich A (2008)

Intentional ABO-incompatible lung transplantation.

Am J Transplant. 2008 Nov;8(11):2476-8. doi: 10.1111/j.1600-6143.2008.02405.x. Epub 2008 Sep 19.

2007

Goerler H, Warnecke G, Winterhalter M, Müller C, Ballmann M, Wessel A, Haverich A, Strüber M, Simon A (2007)

Heart-lung transplantation in a 14-year-old boy with Alström syndrome.

J Heart Lung Transplant. 2007 Nov;26(11):1217-8.

 

Strüber M, Fischer S, Niedermeyer J, Warnecke G, Gohrbandt B, Görler A, Simon AR, Haverich A, Hohlfeld JM (2007)

Effects of exogenous surfactant instillation in clinical lung transplantation: a prospective, randomized trial.

J Thorac Cardiovasc Surg. 2007 Jun;133(6):1620-5.

 

2006

Warnecke G, Avsar M, Morancho M, Peters C, Thissen S, Kruse B, Baumann R, Ungefroren H, Simon AR, Hohlfeld JM, Karstens JH, Haverich A, Strüber M (2006)

Preoperative low-dose irradiation promotes long-term allograft acceptance and induces regulatory T cells in a porcine model of pulmonary transplantation.

Transplantation. 2006 Jul 15;82(1):93-101.

 

Bara C, Ghodsizad A, Niehaus M, Makoui M, Piechaczek C, Martin U, Warnecke G, Karck M, Gams E, Klein HM, Haverich A, Ruhparwar A (2006)

In vivo echocardiographic imaging of transplanted human adult stem cells in the myocardium labeled with clinically applicable CliniMACS nanoparticles.

J Am Soc Echocardiogr. 2006 May;19(5):563-8.

 

Gohrbandt B, Fischer S, Warnecke G, Avsar M, Sommer SP, Haverich A, Strueber M (2006)

Glycine intravenous donor preconditioning is superior to glycine supplementation to low-potassium dextran flush preservation and improves graft function in a large animal lung transplantation model after 24 hours of cold ischemia.

J Thorac Cardiovasc Surg. 2006 Mar;131(3):724-9.

 

Warnecke G, Schulze B, Steinkamp T, Haverich A, Klima U (2006)

Glycine application and right heart function in a porcine heart transplantation model.

Transpl Int. 2006 Mar;19(3):218-24.

 

2005

Warnecke G, Avsar M, Steinkamp T, Reinhard R, Niedermeyer J, Simon AR, Haverich A, Strüber M (2005)

Tacrolimus versus cyclosporine induction therapy in pulmonary transplantation in miniature swine.

Eur J Cardiothorac Surg. 2005 Sep;28(3):454-60.

 

Sommer SP, Gohrbandt B, Fischer S, Hohlfeld JM, Warnecke G, Avsar M, Strüber M (2005)

Glutathione improves the function of porcine pulmonary grafts stored for twenty-four hours in low-potassium dextran solution.

J Thorac Cardiovasc Surg. 2005 Sep;130(3):864-9.

 

Klima U, Ringes-Lichtenberg S, Warnecke G, Lichtenberg A, Strüber M, Haverich A (2005)

Severe right heart failure after heart transplantation. A single-center experience.

Transpl Int. 2005 Mar;18(3):326-32.

 

Gohrbandt B, Warnecke G, Fischer S, Haverich A, Strueber M (2005)

A novel technique for semiselective in situ bronchial artery perfusion in human lung retrieval.

J Thorac Cardiovasc Surg. 2005 Feb;129(2):456-7. No abstract available.

 

Gohrbandt B, Sommer SP, Fischer S, Hohlfeld JM, Warnecke G, Haverich A, Strueber M (2005)

Iloprost to improve surfactant function in porcine pulmonary grafts stored for twenty-four hours in low-potassium dextran solution.

J Thorac Cardiovasc Surg. 2005 Jan;129(1):80-6.

 

2004

Sommer SP, Warnecke G, Hohlfeld JM, Gohrbandt B, Niedermeyer J, Kofidis T, Haverich A, Strüber M (2004)

Pulmonary preservation with LPD and celsior solution in porcine lung transplantation after 24 h of cold ischemia.

Eur J Cardiothorac Surg. 2004 Jul;26(1):151-7.

 

Warnecke G, Sommer SP, Gohrbandt B, Fischer S, Hohlfeld JM, Niedermeyer J, Haverich A, Strüber M (2004)

Warm or cold ischemia in animal models of lung ischemia-reperfusion injury: is there a difference?

Thorac Cardiovasc Surg. 2004 Jun;52(3):174-9. No abstract available.

 

Tegtbur U, Sievers C, Busse MW, Pethig K, Warnecke G, Kugler C, Gützlaff E, Künsebeck HW, Strüber M, Haverich A, Niedermeyer J (2004)

[Quality of life and exercise capacity in lung transplant recipients].

Pneumologie. 2004 Feb;58(2):72-8. German.

2003

Kutschka I, Sommer SP, Hohlfeld JM, Warnecke G, Morancho M, Fischer S, Haverich A, Strüber M; Hannover Thoracic Transplant Program (2003)

In-situ topical cooling of lung grafts: early graft function and surfactant analysis in a porcine single lung transplant model.

Eur J Cardiothorac Surg. 2003 Sep;24(3):411-9.

 

2002

Warnecke G, Strüber M, Hohlfeld JM, Niedermeyer J, Sommer SP, Haverich A (2002)

Pulmonary preservation with Bretscheider's HTK and Celsior solution in minipigs.

Eur J Cardiothorac Surg. 2002 Jun;21(6):1073-9.

 

Warnecke G, Schulze B, Haverich A, Klima U (2002)

Celsior solution provides superior post-ischemic right ventricular function as compared with UW solution in a porcine heart transplantation model.

J Heart Lung Transplant. 2002 May;21(5):586-9.

 

Strüber M, Hohlfeld JM, Kofidis T, Warnecke G, Niedermeyer J, Sommer SP, Haverich A (2002)

Surfactant function in lung transplantation after 24 hours of ischemia: advantage of retrograde flush perfusion for preservation.

J Thorac Cardiovasc Surg. 2002 Jan;123(1):98-103.

 

Warnecke G, Schulze B, Hagl C, Haverich A, Klima U (2002)

Improved right heart function after myocardial preservation with 2,3-butanedione 2-monoxime in a porcine model of allogenic heart transplantation.

J Thorac Cardiovasc Surg. 2002 Jan;123(1):81-8.

 

2001

Warnecke G, Strüber M, Fraud S, Hohlfeld JM, Haverich A (2001)

Combined exogenous surfactant and inhaled nitric oxide therapy for lung ischemia-reperfusion injury in minipigs.

Transplantation. 2001 May 15;71(9):1238-44.

 

2000

Klima U, Kutschka I, Warnecke G, Kim P, Strüber M, Kirschfink M, Haverich A (2000)

Improved right ventricular function after intracoronary administration of a C1 esterase inhibitor in a right heart transplantation model.

Eur J Cardiothorac Surg. 2000 Sep;18(3):321-7.

 

Strüber M, Hohlfeld JM, Fraund S, Kim P, Warnecke G, Haverich A (2000)

Low-potassium dextran solution ameliorates reperfusion injury of the lung and protects surfactant function.

J Thorac Cardiovasc Surg. 2000 Sep;120(3):566-72.

 

1999

Hohlfeld JM, Strüber M, Ahlf K, Hoeper MM, Fraund S, Krug N, Warnecke G, Harringer W, Haverich A, Fabel H (1999)

Exogenous surfactant improves survival and surfactant function in ischaemia-reperfusion injury in minipigs.

Eur Respir J. 1999 May;13(5):1037-43.