Kliniken & Institute ... SFBs SFB 938 Publikationen

Projekt Z2 – Lasitschka/Enk

Erbel C, Wolf A, Lasitschka F, Linden F, Domschke G, Akhavanpoor M, Doesch AO, Katus HA, Gleissner CA.
Prevalence of M4 macrophages within human coronary atherosclerotic plaques is associated with features of plaque instability. Int J Cardiol. 2015 May 1.
186:219-25. doi: 10.1016/j.ijcard.2015.03.151. Epub 2015 Mar 17. PubMed PMID: 25828120.

Klupp F, Diers J, Kahlert C, Neumann L, Halama N, Franz C, Schmidt T, Lasitschka F, Warth A, Weitz J, Koch M, Schneider M, Ulrich A.
Expressional STAT3/STAT5 Ratio is an Independent Prognostic Marker in Colon Carcinoma. Ann Surg Oncol. 2015 Mar 13.
[Epub ahead of print] PubMed PMID: 25773877.

Schmidt S, Schenkova K, Adam T, Erikson E, Lehmann-Koch J, Sertel S, Verhasselt B, Fackler OT, Lasitschka F, Keppler OT. 
SAMHD1's protein expression profile in humans. J Leukoc Biol. 2015 Feb 2.
pii: jlb.4HI0714-338RR. [Epub ahead of print] PubMed PMID: 25646359.

Szikszai T, Lasitschka F, Giese T, Greulich M, Lee YS, Ilse J, Schiessling S, Leowardi C, Al-Saeedi M, Winter J, Meuer S, Schröder-Braunstein J.
Standardization of a human organ culture model of intestinal inflammation and its application for drug testing. J Immunol Methods. 2014 Dec 31.
pii: S0022-1759(14)00367-6. doi: 10.1016/j.jim.2014.12.014. [Epub ahead of print] PubMed PMID: 25556347.

Behr DS, Peitsch WK, Hametner C, Lasitschka F, Houben R, Schönhaar K, Michel J, Dollt C, Goebeler M, Marx A, Goerdt S, Schmieder A.
Prognostic value of immune cell infiltration, tertiary lymphoid structures and PD-L1 expression in Merkel cell carcinomas. Int J Clin Exp Pathol. 2014 Oct 15.
7(11):7610-21. eCollection 2014. PubMed PMID: 25550797; PubMed Central PMCID: PMC4270630.

Kahlert C, Fiala M, Musso G, Halama N, Keim S, Mazzone M, Lasitschka F, Pecqueux M, Klupp F, Schmidt T, Rahbari N, Schölch S, Pilarsky C, Ulrich A, Schneider M, Weitz J, Koch M.
Prognostic impact of a compartment-specific angiogenic marker profile in patients with pancreatic cancer. Oncotarget. 2014 Dec 30.
5(24):12978-89. PubMed PMID: 25483099; PubMed Central PMCID: PMC4350362.

Akhavanpoor M, Gleissner CA, Gorbatsch S, Doesch AO, Akhavanpoor H, Wangler S, Jahn F, Lasitschka F, Katus HA, Erbel C.
CCL19 and CCL21 modulate the inflammatory milieu in atherosclerotic lesions. Drug Des Devel Ther. 2014 Nov 27.
8:2359-71. doi: 10.2147/DDDT.S72394. eCollection 2014. PubMed PMID: 25473269;

Erbel C, Akhavanpoor M, Okuyucu D, Wangler S, Dietz A, Zhao L, Stellos K, Little KM, Lasitschka F, Doesch A, Hakimi M, Dengler TJ, Giese T, Blessing E, Katus HA, Gleissner CA.
IL-17A Influences Essential Functions of the Monocyte/Macrophage Lineage and Is Involved in Advanced Murine and Human Atherosclerosis. J Immunol. 2014 Nov 1.
193(9):4344-55. doi: 10.4049/jimmunol.1400181. Epub 2014 Sep 26. PubMed PMID: 25261478.

Müller-Stich BP, Senft JD, Lasitschka F, Shevchenko M, Billeter AT, Bruckner T, Kenngott HG, Fischer L, Gehrig T.
Polypropylene, polyester or polytetrafluoroethylene-is there an ideal material for mesh augmentation at the esophageal hiatus? Results from an experimental study in a porcine model. Hernia. 2014 Aug 27.
[Epub ahead of print] PubMed PMID: 25159558.

Erhart P, Grond-Ginsbach C, Hakimi M, Lasitschka F, Dihlmann S, Böckler D, Hyhlik-Dürr A.
Finite element analysis of abdominal aortic aneurysms: predicted rupture risk correlates with aortic wall histology in individual patients. J Endovasc Ther. 2014 Aug.
21(4):556-64. doi: 10.1583/14-4695.1. PubMed PMID: 25101586.

Weitnauer M, Schmidt L, Ng Kuet Leong N, Muenchau S, Lasitschka F, Eckstein V, Hübner S, Tuckermann J, Dalpke AH. 
Bronchial Epithelial Cells Induce Alternatively Activated Dendritic Cells Dependent on Glucocorticoid Receptor Signaling. J Immunol. 2014 Jun 25. 
pii: 1400446 [Epub ahead of print] PubMed PMID: 24965772.

Leuschner F, Courties G, Dutta P, Mortensen LJ, Gorbatov R, Sena B, Novobrantseva TI, Borodovsky A, Fitzgerald K, Koteliansky V, Iwamoto Y, Bohlender M, Meyer S, Lasitschka F, Meder B, Katus HA, Lin C, Libby P, Swirski FK, Anderson DG, Weissleder R, Nahrendorf M. 
Silencing of CCR2 in myocarditis. Eur Heart J. 2014 Jun 20. 
pii: ehu225. [Epub ahead of print] PubMed PMID: 24950695.

Alam MS, Gaida MM, Ogawa Y, Kolios AG, Lasitschka F, Ashwell JD.
Counter-regulation of T cell effector function by differentially activated p38. J Exp Med. 2014 Jun 2;
211(6):1257-70. doi: 10.1084/jem.20131917. Epub 2014 May 26. PubMed PMID: 24863062; PubMed Central PMCID: PMC4042639.

Schröder-Braunstein J, Gras J, Brors B, Schwarz S, Szikszai T, Lasitschka F, Wabnitz G, Heidtmann A, Lee YS, Schiessling S, Leowardi C, Al-Saeedi M, Ulrich A, Engelke A, Winter J, Samstag Y, Giese T, Meuer S.
Initiation of an inflammatory response in resident intestinal lamina propria cells -use of a human organ culture model. PLoS One. 2014 May 19;
9(5):e97780. doi: 10.1371/journal.pone.0097780. eCollection 2014. PubMed PMID: 24841635; PubMed Central PMCID: PMC4026413.

Martins VC, Busch K, Juraeva D, Blum C, Ludwig C, Rasche V, Lasitschka F, Mastitsky SE, Brors B, Hielscher T, Fehling HJ, Rodewald HR.
Cell competition is a tumour suppressor mechanism in the thymus. Nature. 2014 May 22;
509(7501):465-70. doi: 10.1038/nature13317. Epub 2014 May 14. PubMed PMID:24828041.

Senft J, Gehrig T, Lasitschka F, Linke GR, Shevchenko M, Bruckner T, Kenngott HG, Fischer L, Müller-Stich BP.
Influence of weight and structure on biological behavior of polypropylene mesh prostheses placed at the esophageal hiatus. J Laparoendosc Adv Surg Tech A. 2014 Jun;24
(6):383-90. doi: 10.1089/lap.2013.0588. Epub 2014 May 2. PubMed PMID: 24784925.

Natural compounds boldine and menthol are antagonists of human 5-HT(3) receptors: implications for treating gastrointestinal disorders. Neurogastroenterol Motil. 2014 Apr 8
Walstab J, Wohlfarth C, Hovius R, Schmitteckert S, Röth R, Lasitschka F, Wink M, Bönisch H, Niesler B. 
doi: 10.1111/nmo.12334. [Epub ahead of print] PubMed PMID: 24708203.

CXCL4-induced plaque macrophages can be specifically identified by co-expression of MMP7+S100A8+ in vitro and in vivo. Innate Immun. 2014 Mar 24.
Erbel C, Tyka M, Helmes CM, Akhavanpoor M, Rupp G, Domschke G, Linden F, Wolf A, Doesch A, Lasitschka F, Katus HA, Gleissner CA.
[Epub ahead of print] PubMed PMID: 24663337.

On the inflammatory response in metal-on-metal implants. J Transl Med. 2014 Mar 21;12:74.
Dapunt U, Giese T, Lasitschka F, Reinders J, Lehner B, Kretzer JP, Ewerbeck V, Hänsch GM. 
doi: 10.1186/1479-5876-12-74. PubMed PMID: 24650243; PubMed Central PMCID: PMC3994416.

M. Increased expression and activation of Absent in Melanoma 2 inflammasome components in lymphocytic infiltrates of Abdominal Aortic Aneurysms. 
Dihlmann S, Erhart P, Mehrabi A, Nickkholgh A, Lasitschka F, Böckler D, Hakimi
Mol Med. 2014 Mar 5. doi: 10.2119/molmed.2013.00162. [Epub ahead of print] PubMed PMID: 24618883.

Metastasis of prostate cancer and melanoma cells in a preclinical in vivo mouse model is enhanced by L-plastin expression and phosphorylation. Mol Cancer. 2014
Riplinger SM, Wabnitz GH, Kirchgessner H, Jahraus B, Lasitschka F, Schulte B, van der Pluijm G, van der Horst G, Hämmerling GJ, Nakchbandi I, Samstag Y.
Jan 18;13:10. doi: 10.1186/1476-4598-13-10. PubMed PMID: 24438191; PubMed Central PMCID: PMC3899628.

Tumour-site-dependent expression profile of angiogenic factors in tumour-associated stroma of primary colorectal cancer and metastases.
Kahlert C, Pecqueux M, Halama N, Dienemann H, Muley T, Pfannschmidt J, Lasitschka F, Klupp F, Schmidt T, Rahbari N, Reissfelder C, Kunz C, Benner A, Falk C, Weitz J, Koch M.
Br J Cancer. 2013 Nov 28. doi: 10.1038/bjc.2013.745. [Epub ahead of print] PMID:24292449 [PubMed - as supplied by publisher]

Endolumenal colon occlusion device for transanal and transrectal surgery-a porcine feasibility study.
Linke GR, Carstensen B, Kähler G, Zerz A, Shevchenko M, Warschkow R, Lasitschka F, Kenngott HG, Senft J, Müller-Stich BP.
Langenbecks Arch Surg. 2013 Apr;398(4):595-601. doi: 10.1007/s00423-013-1074-5. Epub 2013 Mar 13. PubMed PMID: 23483227.

Mutant BRAF V600E protein in ganglioglioma is predominantly expressed by neuronal tumor cells.
Koelsche C, Wöhrer A, Jeibmann A, Schittenhelm J, Schindler G, Preusser M, Lasitschka F, von Deimling A, Capper D.
Acta Neuropathol. 2013 Feb 24. [Epub ahead of print] PubMed PMID: 23435618.

Identification of the novel differentiation marker MS4A8B and its murine homolog MS4A8A in colonic epithelial cells lost during neoplastic transformation in human colon. (PubMed)
Michel J, Schönhaar K, Schledzewski K, Gkaniatsou C, Sticht C, Kellert B, Lasitschka F, Géraud C, Goerdt S, Schmieder A.
Cell Death Dis. 2013 Jan 24;4:e469. doi: 10.1038/cddis.2012.215. PubMed PMID: 23348583; PubMed Central PMCID: PMC3564002

Methylglyoxal modification of Na(v)1.8 facilitates nociceptive neuron firing and causes hyperalgesia in diabetic neuropathy. (PubMed)
Bierhaus A, Fleming T, Stoyanov S, Leffler A, Babes A, Neacsu C, Sauer SK, Eberhardt M, Schnölzer M, Lasischka F, Neuhuber WL, Kichko TI, Konrade I, Elvert R, Mier W, Pirags V, Lukic IK, Morcos M, Dehmer T, Rabbani N, Thornalley PJ, Edelstein D, Nau C, Forbes J, Humpert PM, Schwaninger M, Ziegler D, Stern DM, Cooper ME, Haberkorn U, Brownlee M, Reeh PW, Nawroth PP.
Nat Med. 2012 May 13. doi: 10.1038/nm.2750.

Myocardial infarction accelerates atherosclerosis. (PubMed)
Dutta P, Courties G, Wei Y, Leuschner F, Gorbatov R, Robbins CS, Iwamoto Y, Thompson B, Carlson AL, Heidt T, Majmudar MD, Lasitschka F, Etzrodt M, Waterman P, Waring MT, Chicoine AT, van der Laan AM, Niessen HW, Piek JJ, Rubin BB, Butany J, Stone JR, Katus HA, Murphy SA, Morrow DA, Sabatine MS, Vinegoni C, Moskowitz MA, Pittet MJ, Libby P, Lin CP, Swirski FK, Weissleder R, Nahrendorf M.
Nature. 2012 Jul 19;487(7407):325-9.

SAMHD1 restricts HIV-1 infection in resting CD4(+) T cells. (PubMed)
Baldauf HM, Pan X, Erikson E, Schmidt S, Daddacha W, Burggraf M, Schenkova K, Ambiel I, Wabnitz G, Gramberg T, Panitz S, Flory E, Landau NR, Sertel S, Rutsch F, Lasitschka F, Kim B, König R, Fackler OT, Keppler OT.
Nat Med. 2012 Sep 12. doi: 10.1038/nm.2964.

BRAFV600E mutant protein is expressed in cells  of variable maturation in Langerhans cell histiocytosis. (PubMed)
Sahm F, Capper D, Preusser M, Meyer J, Stenzinger A, Lasitschka F, Berghoff AS, Habel A, Schneider M, Kulozik A, Anagnostopoulos I, Müllauer L, Mechtersheimer G, von Deimling A.
Blood. 2012 Sep 20;120(12):e28-34. Epub 2012 Aug 2.

BRAF V600E expression and distribution in desmoplastic infantile astrocytoma / ganglioglioma
Koelsche C, Sahm F, Paulus W, Mittelbronn M, Giangaspero F, Antonelli M, Meyer J, Lasitschka F, von Deimling A, Reuss D. 
Neuropathol Appl Neurobiol. 2013 Jul 4. doi: 10.1111/nan.12072. [Epub ahead of print] PubMed PMID: 23822828.

complex secretory program orchestrated by the inflammasome controls paracrine senescence
Acosta JC, Banito A, Wuestefeld T, Georgilis A, Janich P, Morton JP, Athineos
D, Kang TW, Lasitschka F, Andrulis M, Pascual G, Morris KJ, Khan S, Jin H,
Dharmalingam G, Snijders AP, Carroll T, Capper D, Pritchard C, Inman GJ,
Longerich T, Sansom OJ, Benitah SA, Zender L, Gil J. A 

Nat Cell Biol. 2013 Jun 16. doi: 10.1038/ncb2784. [Epub ahead of print] PubMed PMID: 23770676.