Kliniken & Institute … Institute Zentrum für… Parasitology Unit Research Lanzer Lab Publications

Selected publications of the Lanzer group

Most recent (last 5 years)

Frohlich B, Jager J, Lansche C, Sanchez CP, Cyrklaff M, Buchholz B, Soubeiga ST, Simpore J, Ito H, Schwarz US, Lanzer M, Tanaka M (2019) Hemoglobin S and C affect biomechanical membrane properties of P. falciparum-infected erythrocytes. Communications biology 2: 311

Sanchez CP, Moliner Cubel S, Nyboer B, Jankowska-Dollken M, Schaeffer-Reiss C, Ayoub D, Planelles G, Lanzer M (2019) Phosphomimetic substitution at Ser-33 of the chloroquine resistance transporter PfCRT reconstitutes drug responses in Plasmodium falciparum. J Biol Chem

Sanchez CP, Karathanasis C, Sanchez R, Cyrklaff M, Jager J, Buchholz B, Schwarz US, Heilemann M, Lanzer M (2019) Single-molecule imaging and quantification of the immune-variant adhesin VAR2CSA on knobs of Plasmodium falciparum-infected erythrocytes. Communications biology 2: 172

Lansche C, Dasanna AK, Quadt K, Fröhlich B, Missirlis D, Tétard M, Gamain B, Buchholz B, Sanchez CP, Tanaka M, Schwarz US, Lanzer M (2018) The sickle cell trait affects contact dynamics and endothelial cell activation in Plasmodium falciparum-infected erythrocytes. Communications Biology 1: 211 Full Text

Duffey M, Sanchez CP, Lanzer M (2018) Profiling of the anti-malarial drug candidate SC83288 against artemisinins in Plasmodium falciparum. Malar J 17: 121   

Frank V, Chushkin Y, Frohlich B, Abuillan W, Rieger H, Becker AS, Yamamoto A, Rossetti FF, Kaufmann S, Lanzer M, Zontone F, Tanaka M (2017) Lensless Tomographic Imaging of Near Surface Structures of Frozen Hydrated Malaria-Infected Human Erythrocytes by Coherent X-Ray Diffraction Microscopy. Scientific reports 7: 14081

Djuika CF, Staudacher V, Sanchez CP, Lanzer M, Deponte M (2017) Knockout of the peroxiredoxin 5 homologue PFAOP does not affect the artemisinin susceptibility of Plasmodium falciparum. Scientific reports 7: 4410

Dasanna AK, Lansche C, Lanzer M, Schwarz US (2017) Rolling Adhesion of Schizont Stage Malaria-Infected Red Blood Cells in Shear Flow. Biophysical journal 112: 1908-1919

Bakouh N, Bellanca S, Nyboer B, Moliner Cubel S, Karim Z, Sanchez CP, Stein WD, Planelles G, Lanzer M (2017) Iron is a substrate of the Plasmodium falciparum chloroquine resistance transporter PfCRT in Xenopus oocytes. J Biol Chem 292: 16109-16121

Jida M, Sanchez CP, Urgin K, Ehrhardt K, Mounien S, Geyer A, Elhabiri M, Lanzer M, Davioud-Charvet E (2017) A Redox-Active Fluorescent pH Indicator for Detecting Plasmodium falciparum Strains with Reduced Responsiveness to Quinoline Antimalarial Drugs. ACS infectious diseases 3: 119-131                  

Waldecker M, Dasanna AK, Lansche C, Linke M, Srismith S, Cyrklaff M, Sanchez CP, Schwarz US, Lanzer M (2017) Differential time-dependent volumetric and surface area changes and delayed induction of new permeation pathways in P. falciparum-infected hemoglobinopathic erythrocytes. Cell Microbiol 19

Urgin K, Jida M, Ehrhardt K, Muller T, Lanzer M, Maes L, Elhabiri M, Davioud-Charvet E (2017) Pharmacomodulation of the Antimalarial Plasmodione: Synthesis of Biaryl- and N-Arylalkylamine Analogues, Antimalarial Activities and Physicochemical Properties. Molecules 22

Pegoraro S, Duffey M, Otto TD, Wang Y, Rosemann R, Baumgartner R, Fehler SK, Lucantoni L, Avery VM, Moreno-Sabater A, Mazier D, Vial HJ, Strobl S, Sanchez CP, Lanzer M (2017) SC83288 is a clinical development candidate for the treatment of severe malaria. Nature communications 8: 14193

Rhiel M, Bittl V, Tribensky A, Charnaud SC, Strecker M, Muller S, Lanzer M, Sanchez C, Schaeffer-Reiss C, Westermann B, Crabb BS, Gilson PR, Kulzer S, Przyborski JM (2016) Trafficking of the exported P. falciparum chaperone PfHsp70x. Scientific reports 6: 36174

Przyborski JM, Nyboer B, Lanzer M (2016) Ticket to ride: export of proteins to the Plasmodium falciparum-infected erythrocyte. Mol Microbiol 101: 1-11 Helms G, Dasanna AK, Schwarz US, Lanzer M (2016) Modeling cytoadhesion of Plasmodium falciparum-infected erythrocytes and leukocytes-common principles and distinctive features. FEBS Lett 590: 1955-1971

Ehrhardt K, Deregnaucourt C, Goetz AA, Tzanova T, Gallo V, Arese P, Pradines B, Adjalley SH, Bagrel D, Blandin S, Lanzer M, Davioud-Charvet E (2016) The Redox Cycler Plasmodione Is a Fast-Acting Antimalarial Lead Compound with Pronounced Activity against Sexual and Early Asexual Blood-Stage Parasites. Antimicrob Agents Chemother 60: 5146-5158  

Staudacher V, Djuika CF, Koduka J, Schlossarek S, Kopp J, Buchler M, Lanzer M, Deponte M (2015) Plasmodium falciparum antioxidant protein reveals a novel mechanism for balancing turnover and inactivation of peroxiredoxins. Free radical biology & medicine 85: 228-236

Petersen I, Gabryszewski SJ, Johnston GL, Dhingra SK, Ecker A, Lewis RE, de Almeida MJ, Straimer J, Henrich PP, Palatulan E, Johnson DJ, Coburn-Flynn O, Sanchez C, Lehane AM, Lanzer M, Fidock DA (2015) Balancing drug resistance and growth rates via compensatory mutations in the Plasmodium falciparum chloroquine resistance transporter. Mol Microbiol 97: 381-395

Rieger H, Yoshikawa HY, Quadt K, Nielsen MA, Sanchez CP, Salanti A, Tanaka M, and Lanzer M (2015) Cytoadhesion of Plasmodium falciparum-infected erythrocytes to chondroitin-4-sulfate is cooperative and shear enhanced. Blood 125: 383-391

Kilian N, Srismith S, Dittmer M, Ouermi D, Bisseye C, Simpore J, Cyrklaff M, Sanchez CP, and Lanzer M (2015) Hemoglobin S and C affect protein export in Plasmodium falciparum-infected erythrocytes. Biology open 

 

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