Kliniken & Institute ... Kliniken Zentrum für Innere... Innere Medizin III:... Forschung Grundlagenforschung ... Cardiac Proteostasis ... Publications

Publications

  1.  Doroudgar S, Völkers M, Thuerauf DJ, Khan M, Mohsin K, Wang W, Respress JL, Gude N, Müller OJ, Wehrens XHT, Sussman MA, Glembotski CC.  (2015)  Hrd1 is a Critical Element of the Sarcoplasmic/Endoplasmic Reticulum Quality Control in the Heart. Circ Res. 2015;117:536-546.
    A commentary on this article appears as follows:  
    Sun H, Gao C, Wang Y.  A H(a)rd Way to Adapt in Cardiac Hypertrophy. (2015) Circ Res. 2015;117:484-486.
  2. Völkers M, Doroudgar S, Konstandin MH, Quijada P, Din S, Ornelas L, Thuerauf DJ, Gude N, Glembotski CC, Sussman MA.  (2014) PRAS40 Prevents Development of Diabetic Cardiomyopathy and Improves Hepatic Insulin Sensitivity in Obesity. EMBO Mol Med. 2014 Jan 1;6(1):57-65.
  3. Völkers M, Konstandin MH, Doroudgar S, Toko H, Quijada P, Din S, Joyo A, Ornelas L, Thuerauf DJ, Gude N, Glembotski CC, Sussman MA. (2013) mTORC2 Protects the Heart from Ischemic Damage.  Circulation. 2013 Sep 5.
  4.  Völkers M, Toko H, Doroudgar S, Din S, Quijada P, Joyo A, Ornelas L, Joyo E, Sin J, Rubio M, Thuerauf DJ, Konstandin MH, Gude N, Glembotski CC, Sussman MA. (2013) Pathological Hypertrophy Amelioration by PRAS40-mediated Inhibition of mTORC1.   Proc Natl Acad Sci U S A. 2013 Jul 30;110(31):12661-6.
  5. Toko H, Konstandin MH, Doroudgar S, Ormachea L, Joyo E, Joyo A, Din S, Gude N, Collins B, Völkers M, Thuerauf DJ, Glembotski CC, Lu KP, Uchida T, Sussman MA.  (2013) Regulation of Cardiac Hypertrophic Signaling by Prolyl Isomerase Pin1.  Circ Res. 2013 Apr 26;112(9):1244-52.
  6. Doroudgar S, Glembotski CC.  (2013) ATF6 and Thrombospondin-4:  The Dynamic Duo of Physiological ER Stress in the Heart.  Circ Res. Jan 4;112(1):9-12.
  7. Doroudgar S, Glembotski CC. (2013) New Concepts of Endoplasmic Reticulum Function in the Heart: Programmed to Conserve.  J Mol Cell Cardiol. 2013 Feb;55:85-91.
  8. Eletto D, Maganty A, Eletto D, Dersh D, Makarewich C, Biswas C, Doroudgar S, Glembotski CC, Argon Y. (2012) Limitation of Individual Folding Resources in the ER Leads to Outcomes Distinct from the Unfolded Protein Response.  J Cell Sci. 2012 Oct 15;125(Pt 20):4865-75.
  9. Glembotski CC, Thuerauf DJ, Huang C, Vekich JA, Gottlieb RA, Doroudgar S.  (2012) Mesencephalic Astrocyte-derived Neurotrophic Factor (MANF) Protects the Heart from Ischemic Damage and is Selectively Secreted upon ER Calcium Depletion.  J Biol Chem. 287(31):25893-904.
  10. Doroudgar S, Glembotski CC. (2012)  Communication in the Heart: Cardiokines as Mediators of a Molecular Social Network.  Book chapter in Muscle:  Fundamental Biology and Mechanisms of Disease.  Elsevier, 2012.  Print.
  11. Doroudgar S, Glembotski CC. (2011) The Cardiokine Story Unfolds: Ischemic Stress-induced Protein Secretion in the Heart.  Trends Mol Med. 17(4):207-14.
  12. Doroudgar S, Thuerauf DJ, Marcinko MC, Belmont PJ, Glembotski CC. (2009) Ischemia Activates the ATF6 Branch of the Endoplasmic Reticulum (ER) Stress Response.  J. Biol. Chem. 284: 29735-29745.