Kliniken & Institute … Kliniken Zentrum für Innere… Innere Medizin V:… Behandlungsspektrum … Hämatologie MDS Publikationen

Ausgewählte Publikationen


1. Conzelmann M, Wagner AH, Hildebrandt A, Rodionova E, Hess M, Zota A, Giese T, Falk CS, Ho AD, Dreger P, Hecker M, Luft T:  IFN-gamma activated JAK1 shifts CD40-induced cytokine profiles in human antigen-presenting cells toward high IL-12p70 and low IL-10 production.
Biochem Pharmacol. 2010 Aug 13. Epub ahead of print

2. Andrulis M, Capper D, Luft T, Hartmann C, Zentgraf H, von Deimling A: Detection of isocitrate dehydrogenase 1 mutation R132H in myelodysplastic syndrome by mutation-specific antibody and direct sequencing.
Leuk Res. 2010 Aug;34(8):1091-3.

3. Thomas Luft, Michael Conzelmann, Elena Rodionova, Michael Hess, Ulrich Strohhaecker, Axel Benner, Martin Görner, Ute Hegenbart, Anthony D. Ho and Peter Dreger: Serum cytokeratin-18 fragments as quantitative marker of epithelial apoptosis in intestinal and hepatic graft-versus-host disease.
Blood. 2007 Dec 15;110(13):4535-42.

4. Elena Rodionova, Michael Conzelmann, Eugene Maraskovsky, Michael Hess, Michael Kirsch, Thomas Giese, Anthony D. Ho, Margot Zöller, Peter Dreger, and Thomas Luft: GSK-3 mediates differentiation and activation of pro-inflammatory dendritic cells.  Blood, 2007, 109(4):1584-92

5. Luft T, Rodionova E, Maraskovsky E, Kirsch M, Hess M, Buchholtz C, Goerner M, Schnurr M, Skoda R, and Ho AD. Adaptive functional differentiation of dendritic cells: integrating the network of extra- and intracellular signals.
Blood 2006; 107(12):4763-9.

Luft, T., Eugene Maraskovsky, Katja Knebel, Michael Kirsch, Martin Görner, Radek Skoda, Anthony D. Ho, Peter Nawroth and Angelika Bierhaus. Tuning the volume of the immune response: Strength and persistence of activation determine functional DC
Blood. 2004 Aug 15;104(4):1066-74

Luft,T.,  Marion Moos, Hartmut Goldschmidt, Anthony D. Ho and Martin Görner. Dissociation of putative graft-versus-hematopoiesis and graft-versus-myeloma effects in patients with rapidly progressive multiple myeloma
Br J Haematol. 2003 Nov;123(4):646-53

6. Luft, T., Jefford, M., Luetjens, P., Toy, T., Hochrein, H., Masterman, KA., Maliszewski, C., Shortman, K., Cebon, J., and Maraskovsky, E. Functionally distinct DC populations induced by physiologic stimuli: Prostaglandin E2 (PGE2) regulates the migratory capacity of specific DC subsets.
Blood 2002, 100(4): 1362-72

7. Luft, T., M. Jefford, P. Luetjens, H. Hochrein, K. Masterman, C. Maliszewski, J. Cebon, and E. Maraskovsky. IL-1b enhances CD40L-mediated cytokine secretion by human Dendritic Cells (DC) - a mechanism for T cell independent DC activation.
J Immunol. 2002 Jan15;  168(2):2529-37.

8. Luft T, Pang KC, Thomas E, Hertzog P, Hart DN, Trapani J, Cebon J
Type I IFNs enhance the terminal differentiation of dendritic cells.
J Immunol 1998 Aug 15;161(4):1947-53