Kliniken & Institute … Kliniken Zentrum für Orthopädie,… Klinik für Orthopädie… Forschung Heidelberg Trauma… Heidelberg Trauma… Publikationen

Publikationen

HTRG

Publikationen 2017

Tracking Spinal Cord Injury: Differences in Cytokine Expression of IGF-1, TGF- B1, and sCD95l Can Be Measured in Blood Samples and Correspond to Neurological Remission in a 12-Week Follow-Up.
Ferbert T, Child C, Graeser V, Swing T, Akbar M, Heller R, Biglari B, Moghaddam A. J Neurotrauma

Reconstruction of Extended Bone Defects Using Massive Allografts Combined with Surgical Angiogenesis: A Case Report.
Struckmann V, Schmidmaier G, Ferbert T, Kneser U, Kremer T. JBJS Case Connect

Micro-Computed-Tomography-Guided Analysis of In Vitro Structural Modifications in Two Types of 45S5 Bioactive Glass Based Scaffolds.
Westhauser F, Ciraldo F, Balasubramanian P, Senger AS, Schmidmaier G, Moghaddam A, Boccaccini AR. Materials (Basel)

Continuous stimulation with differentiation factors is necessary to enhance osteogenic differentiation of human mesenchymal stem cells in-vitro.
Reible B, Schmidmaier G, Prokscha M, Moghaddam A, Westhauser F. Growth Factors

In Vivo Models for the Evaluation of the Osteogenic Potency of Bone Substitutes Seeded with Mesenchymal Stem Cells of Human Origin: A Concise Review.
Westhauser F, Senger AS, Reible B, Moghaddam A. Tissue Eng Part C Methods

Clinical experiences in the use of a gentamicin-coated titanium nail in tibia fractures.
Schmidmaier G, Kerstan M, Schwabe P, Südkamp N, Raschke M. Injury

CCL-2 as a possible early marker for remission after traumatic spinal cord injury.
Heller RA, Raven TF, Swing T, Kunzmann K, Daniel V, Haubruck P, Akbar M, Grützner PA, Schmidmaier G, Biglari B, Moghaddam A. Spinal Cord.

Use of the Suprapatellar Approach in Intramedullary Nailing of a Multi-Fragmentary Dislocated Tibia Fracture with a Hypermobile Intermediate Fragment in a Young Patient.
Haubruck P, Brunnemer U, Moghaddam A, Schmidmaier G. Orthop Rev (Pavia).

Osteointegration and Resorption of Intravertebral and Extravertebral Calcium Phosphate Cement.
Klein R, Tetzlaff R, Weiss C, Schäfer MK, Tanner M, Wiedenhöfer B, Grafe I, Meeder PJ, Noeldge G, Nawroth PP, Kasperk C. Clin Spine Surg

A Pronounced Inflammatory Activity Characterizes the Early Fracture Healing Phase in Immunologically Restricted Patients.
Hoff P, Gaber T, Strehl C, Jakstadt M, Hoff H, Schmidt-Bleek K, Lang A, Röhner E, Huscher D, Matziolis G, Burmester GR, Schmidmaier G, Perka C, Duda GN, Buttgereit F. Int J Mol Sci.

App-based serious gaming for training of chest tube insertion: study protocol for a randomized controlled trial.
Friedrich M, Bergdolt C, Haubruck P, Bruckner T, Kowalewski KF, Müller-Stich BP, Tanner MC, Nickel F. Trials

Dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) for the prediction of non-union consolidation.
Fischer C, Nissen M, Schmidmaier G, Bruckner T, Kauczor HU, Weber MA.  Injury.

[Susceptibility to infections and behavior of stainless steel : Comparison with titanium implants in traumatology].
Haubruck P, Schmidmaier G. Unfallchirurg

Mesenchymal stem cells from reaming material possess high osteogenic potential and react sensitively to bone morphogenetic protein 7.
Hoellig M, Westhauser F, Kornienko K, Xiao K, Schmidmaier G, Moghaddam A. J Appl Biomater Funct Mater.

[Tibial defects and infected non-unions : Treatment results after Masquelet technique].
Moghaddam A, Ermisch C, Fischer C, Zietzschmann S, Schmidmaier G. Der Orthopäde.

Exploratory study to suggest the possibility of MMP-8 and MMP-9 serum levels as early markers for remission after traumatic spinal cord injury.
Moghaddam A, Heller R, Daniel V, Swing T, Akbar M, Gerner HJ, Biglari B. Spinal Cord

Dynamic contrast-enhanced ultrasound and elastography assess deltoid muscle integrity after reverse shoulder arthroplasty.
Fischer C, Krammer D, Hug A, Weber MA, Kauczor HU, Krix M, Bruckner T, Kunz P, Schmidmaier G, Zeifang F. J Shoulder Elbow Surg

Antibiotikabeschichtete Implantate in der Unfallchirurgie
Patrick Haubruck, Gerhard Schmidmaier. OP-Journal

PUBLIKATIONEN 2016

Mesenchymal stem cells from reaming material possess high osteogenic potential and react sensitively to bone morphogenetic protein 7.
Hoellig M, Westhauser F, Kornienko K, Xiao K, Schmidmaier G, Moghaddam A. J Appl Biomater Funct Master. 2016 Dec 19:D. doi 10.5301/jabfm.5000333.

Treatment of atrophic femoral non-unions according to the diamond concept: Results of one- and two-step surgical procedure.
Moghaddam A, Thaler B, Bruckner T, Tanner M, Schmidmaier G. J Orthop. 2016 Nov 2;14(1):123-133. eCollection 2017.

sCD95L in serum after spinal cord injury.
Moghaddam A, Sperl A, Heller R, Gerner HJ, Biglari B. Spinal Cord. 2016 Nov;54(11):957-960. Doi: 10.1038/sc.2016.44. Epub 2016 Apr 19.

The treatment of nonunions with application of BMP-7 increases the expression pattern for angiogenic an inflammable cytokines: a matched pair analysis.
Haubruck P, Kammerer A, Korff S, Apitz P, Xiao K, Büchler A, Biglari B, Zimmermann G, Daniel V, Schmidmaier G, Moghaddam A. J Inflamm Res. 2016 Sep 22;9:155-165. eCollection 2016.

Patients’ safety: is there a systemic release of gentamicin by gentamicin-coated tibia nails in clinical use?
Moghaddam A, Graeser V, Westhauser F, Dapunt U, Kamradt T, Woerner SM, Schmidmaier G. Ther Clin Risk Manag. 2016 Sep 7;12:1387-93. Doi: 10.2147/TCRM.S107398. eCollection  2016.

Does surgical treatment wihin 4 hours after trauma have an influence on neurological remission in patients with acute spinal cord injury?
Biglari B, Child C, Yildrim TM, Swing T, Reitzel T, Moghaddam A. Ther Clin Risk Manag. 2016 Aug 31;12:1339-46. Doi: 10.2147/TCRM.S108856. eCollection 2016.

Bone formation of human mesenchymal stem cells harvested from reaming debris is stimulated by low-dose bone morphogenetic protein-7 apliccation in vivo.
Westhauser F, Höllig M, Reible B, Xiao K, Schmidmaier G, Moghaddam A. J Orthop. 2016 Aug 29;13(4):404-8. Doi: 10.1016/j.jor.2016.08.002. eCollection 2016.

Treatment with recombinant human bone morphogenetic protein 7 leads to a transient induction of neutralizing autoantibodies in a subset of patients.
Schuette A, Moghaddam A, Seemann P, Duda GN, Schmidmaier G, Schomburg L. BBA Clin. 2016 Aug 3;6:100-7. Doi: 10.1016/j.bbacli.2016.08.001. eCollection 2016.

Tracking Spinal Cord Injury: Differences in Cytokine Expression of IGF-1, TGF-B1, and sCD95I Can Be Measured in Blood Samples and Correspond to Neurological Remission in a 12-Week Follow-Up.
Ferbert T, Child C, Graeser V, Swing T, Akbar M, Heller R, Biglari B, Moghaddam A. J Neurotrauma. 2016 Oct 12. Doi: 10.1089/neu.2015.4294.

[Tibial defects and infected non-unions: Treatment results after Masquelet technique].
Moghaddam A, Ermisch C, Fischer C, Zietzschmann S, Schmidmaier G. Orthopade. 2016 Aug 4. Doi: 10.1007/s00132-016-3305-2.

Elevated Serum Insulin-Like Growth Factor 1 Levels in Patients with Neurological Remission after Traumatic Spinal Cord Injury.
Moghaddam A, Sperl A, Heller R, Kunzmann K, Graesen V, Akbar M, Gerner HJ, Biglari B. PLoS One. 2016 Jul 22;11(7):e0159764. Doi: 10.1371/journal.pone.0159764. eCollection 2016.

Low intensity pulsed ultrasound in the treatment of long bone nonunions: Evaluation of cytokine expression as a tool for objectifying nonunion therapy.
Moghaddam A, Yildrim TM, Westhauser F, Danner W, Swing T, Bruckner T, Biglari B. J Orthop. 2016 Jul 2;13(4):306-12. Doi: 10.1016/j.jor.2016.06.028. eCollection 2016.

Failed treatment of long bone nonunions with low intensity pulsed ultrasound.
Biglari B, Yildrim TM, Swing T, Bruckner T Danner W, Moghaddam A. Arch Orthop Träume Surg. 2016 Aug;136(8):1121-34. Doi: 10.1007/s00402-016-2501-1. Epub 2016 Jul 6.

Exploratory study to suggest the possibility of MMP-8 and MMP-9 serum levels as early markers for remission after traumatic spinal cord injury.
Moghaddam A, Heller R, Daniel V, Swing T, Akbar M, Gerner HJ, Biglari B. Spinal Cord. 2017 Jan;55(1):8-15. Doi: 10.1038/sc.2016.104. Epub 2016 Jul 5.

Three-dimensional polymer coated 45S5-type bioactive glass scaffolds seeded with human mesenchymal stem cells show bone formation in vivo.
Westhauser F, Weis C, Prokscha M, Bittrich LA, Li W, Xiao K, Kneser U, Kauczor HU, Schmidmaier G, Boccaccini Ar, Moghaddam A. J Mater Sci Mater Med. 2016 Jul;27(7):119. Doi: 10.1007/s10856-016-5732-3. Epub 2016 Jun 7.

The osteoblast as an inflammatory cell: production of cytokines in response to bacteria and components of bacterial biofilms.
Dapunt U, Giese T, Stegmaier S Moghaddam A, Hänsch GM. BMC Musculoskelet Disord. 2016 Jun 2;17:243. Doi: 10.1186/s12891-016-1091-y.

Dynamic contrast-enhanced ultrasound (CEUS) after open and minimally invasive locked platingg of proximal humerus fractures.
Fischer C, Frank M, Kunz P, Tanner M, Weber MA, Moghaddam A, Schmidmaier G, Hug A. Injury. 2016 Aug;47(8):1725-31. Doi: 10.1016.05.005. Epub 2016 May 14.

Outcome of Radial Head Arthroplasty in Comminuted Radial Head Fractures: Short and Midterm Results.
Moghaddam A, Raven TF, Dremel E, Studier-Fischer S, Grutzner PA, Biglari B. Trauma Mon. 2016 Feb 6;21(1):e20201. Doi: 10.5812/traumamon.20201. eCollection 2016.

Non-unions treated with bone morphogenetic protein 7: introducing the quantitative measurement of human serum cytokine levels as promising tool in evaluation of adjunct non-union therapy.
Moghaddam A, Breier L, Haubruck P, Bender D, Biglari B, Wentzensen A, Zimmermann G. J Inflamm (Lond). 2016 Jan 22;13:3. Doi: 10.1186/s12950-016-0111-x. eCollection 2016.

Quantification of TGF-ß1, PDGF an IGF-1 cytokine expression after fracture treatment vs. non-union therapy via masquelet.
Fischer C, Doll J, Tanner M, Bruckner T, Zimmermann G, Helbig L, Biglari B, Schmidmaier G, Moghaddam A. Injury. 2016 Feb;47(2):342-9. Doi: 10.1016/j.injury.2015.11.007. Epub 2015 Dec 17.

Treatment of nonunions in fractures oft he humeral shaft according tot he Diamond Concept.
Miska M, Findeisen S, Tanner M, Biglari B, Studier-Fischer S, Grützner PA, Schmidmaier G, Moghaddam A. Bone Joint J. 2016 Jan;98-B(1):81-7. Doi: 10.1302/0301-620X.98B1.35682.

Publikationen 2015

Non-unions treated with bone morphogenic protein 7: introducing the quantitative measurement of human serum cytokine levels as promising tool in evaluation of adjunct non-union therapy.
Moghaddam A, Breier L, Haubruck P, Bender D, Biglari B, Wentzensen A, Zimmermann G.
J Inflamm (Lond). 2016 Jan 22;13:3. doi: 10.1186/s12950-016-0111-x. eCollection 2016.

Quantification of TGF-ß1, PDGF and IGF-1 cytokine expression after fracture treatment vs. non-union therapy via masquelet.
Fischer C, Doll J, Tanner M, Bruckner T, Zimmermann G, Helbig L, Biglari B, Schmidmaier G, Moghaddam A.
Injury. 2015 Dec 17. pii: S0020-1383(15)00705-6. doi: 10.1016/j.injury.2015.11.007.

RIA fractions contain mesenchymal stroma cells with high osteogenic potency.
Kuehlfluck P, Moghaddam A, Helbig L, Child C, Wildemann B, Schmidmaier G; HTRG-Heidelberg Trauma Research Group.
Injury. 2015 Dec;46 Suppl 8:S23-32. doi: 10.1016/S0020-1383(15)30051-6.

Treatment of nonunions in fractures of the humeral shaft according to the Diamond Concept.
Miska M, Findeisen S, Tanner M, Biglari B, Studier-Fischer S, Grützner PA, Schmidmaier G, Moghaddam A.
Bone Joint J. 2016 Jan;98-B(1):81-7. doi: 10.1302/0301-620X.98B1.35682.

Are atrophic long-bone nonunions associated with low-grade infections?
Dapunt U, Spranger O, Gantz S, Burckhardt I, Zimmermann S, Schmidmaier G, Moghaddam A.
Ther Clin Risk Manag. 2015 Dec 15;11:1843-52. doi: 10.2147/TCRM.S91532. eCollection 2015.

Heidelberg-mCT-Analyzer: a novel method for standardized microcomputed-tomography-guided evaluation of scaffold properties in bone and tissue research.
Westhauser F, Weis C, Hoellig M, Swing T, Schmidmaier G, Weber MA, Stiller W, Kauczor HU, Moghaddam A.
R Soc Open Sci. 2015 Nov 11;2(11):150496. doi: 10.1098/rsos.150496. eCollection 2015 Nov.

Long Bone Nonunion
Schmidmaier G, Moghaddam A.
Z Orthop Unfall. 2015 Dec;153(6):659-76. doi: 10.1055/s-0035-1558259. Epub 2015 Dec 15. German.

A new animal model for delayed osseous union secondary to osteitis.
Helbig L, Guehring T, Rosenberger S, Ivanova A, Kaeppler K, Fischer CA, Moghaddam A, Schmidmaier G.
BMC Musculoskelet Disord. 2015 Nov 19;16(1):362. doi: 10.1186/s12891-015-0816-7.

Treatment of atrophic tibia non-unions according to 'diamond concept': Results of one- and two-step treatment.
Moghaddam A, Zietzschmann S, Bruckner T, Schmidmaier G.
Injury. 2015 Oct;46 Suppl 4:S39-50. doi: 10.1016/S0020-1383(15)30017-6.

Validity of subjective smoking status in orthopedic patients.
Bender D, Haubruck P, Boxriker S, Korff S, Schmidmaier G, Moghaddam A.
Ther Clin Risk Manag. 2015 Aug 27;11:1297-303. doi: 10.2147/TCRM.S86212. eCollection 2015.

Reaming in treatment of non-unions in long bones: cytokine expression course as a tool for evaluation of non-union therapy.
Westhauser F, Zimmermann G, Moghaddam S, Bruckner T, Schmidmaier G, Biglari B, Moghaddam A.
Arch Orthop Trauma Surg. 2015 Aug;135(8):1107-16. doi: 10.1007/s00402-015-2253-3. Epub 2015 Jun 18.

Posttraumatic inflammation as a key to neuroregeneration after traumatic spinal cord injury.
Moghaddam A, Child C, Bruckner T, Gerner HJ, Daniel V, Biglari B.
Int J Mol Sci. 2015 Apr 9;16(4):7900-16. doi: 10.3390/ijms16047900.

A pilot study on temporal changes in IL-1β and TNF-α serum levels after spinal cord injury: the serum level of TNF-α in acute SCI patients as a possible marker for neurological remission.
Biglari B, Swing T, Child C, Büchler A, Westhauser F, Bruckner T, Ferbert T, Jürgen Gerner H, Moghaddam A.
Spinal Cord. 2015 Jul;53(7):510-4. doi: 10.1038/sc.2015.28. Epub 2015 Mar 10.

A pilot study on the effectiveness of platelet-rich plasma and debridement for the treatment of nonhealing fistulas in spinal cord-injured patients.
Biglari B, Reitzel T, Swing T, Büchler A, Gerner HJ, Schmidmaier G, Moghaddam A.
Adv Skin Wound Care. 2015 Mar;28(3):123-8. doi: 10.1097/01.ASW.0000459845.95441.1a.

Serum sCD95L concentration in patients with spinal cord injury.
Biglari B, Büchler A, Swing T, Child C, Biehl E, Reitzel T, Bruckner T, Ferbert T, Korff S, Rief H, Gerner HJ, Moghaddam A.
J Int Med Res. 2015 Apr;43(2):250-6. doi: 10.1177/0300060514559794. Epub 2015 Jan 19.

Ultrasound vs. MRI in the assessment of rotator cuff structure prior to shoulder arthroplasty.
Fischer CA1, Weber MA2, Neubecker C1, Bruckner T3, Tanner M1, Zeifang F1.
J Orthop. 2015 Jan 28;12(1):23-30. doi: 10.1016/j.jor.2015.01.003. eCollection 2015.

Tissue loss and bone repair: Time to develop an international strategy?
Giannoudis PV, Calori GM, Bégué T, Schmidmaier G.
Injury. 2015 Dec;46 Suppl 8:S1-2. doi: 10.1016/S0020-1383(15)30047-4. No abstract available.