Allgemeine Pathologie
Pathologie

Publikationen


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Top Ten Publikationen


2011

First and Senior Authorship 

 

Kloor M, Voigt AY, Schackert HK, Schirmacher P, von Knebel Doeberitz M,  Blaeker H. (2011) 

Analysis of EPCAM protein expression in diagnostics of Lynch syndrome

J Clin Oncol29(2):223-7. (IF:18.97)

 

Gutschner T, Baas M, Diederichs S. (2011) Noncoding RNA gene silencing through genomic integration of RNA destabilizing elements using zinc finger nucleases

Genome Res. 21(11):1944-54. (IF:13.59)

 

Straub BK, Rickelt S, Zimbelmann R, Grund C, Kuhn C, Iken M, Ott M, Schirmacher P,  Franke WW. (2011) E-N-cadherin heterodimers define novel adherens junctions connecting endoderm-derived cells

J Cell Biol195(5):873-87. (IF:9.92)

 

Brauckhoff A, Malz M, Tschaharganeh D, Malek N, Weber A, Riener MO, Soll C, Samarin J, Bissinger M, Schmidt J, Longerich T, Ehemann V, Schirmacher P,  Breuhahn K. (2011) Nuclear expression of the ubiquitin ligase seven in absentia homolog (SIAH)-1 induces proliferation and migration of liver cancer cells

J Hepatol.  55(5):1049-57. (IF:9.33

Breinig M, Mayer P, Harjung A, Goeppert B, Malz M, Penzel R, Neumann O, Hartmann A, Dienemann H, Giaccone G, Schirmacher P, Kern MA, Chiosis G, Rieker RJ. (2011) Heat shock protein 90-sheltered overexpression of insulin-like growth factor 1 receptor contributes to malignancy of thymic epithelial tumors

Clin Cancer Res.17(8):2237-49. (IF:7.34)

Cooperative Contribution 

 

Haiman CA...., Sinn HP..... Couch FJ. (2011) A common variant at the TERT-CLPTM1L locus is associated with estrogen receptor-negative breast cancer

Nat Genet. 43(12):1210-4. (IF: 36.38)

 

Kang TW, Yevsa T, Woller N, Hoenicke L, Wuestefeld T, Dauch D, Hohmeyer A, Gereke M, Rudalska R, Potapova A, Iken M, Vucur M, Weiss S, Heikenwalder M, Khan S, Gil J, Bruder D, Manns M, Schirmacher P, Tacke F, Ott M, Luedde T, Longerich T, Kubicka S, Zender L. (2011) Senescence surveillance of pre-malignant hepatocytes limits liver cancer development.

Nature. 479(7374):547-51. (IF:36.10)

 

Dieter SM, Ball CR, Hoffmann CM, Nowrouzi A, Herbst F, Zavidij O, Abel U, Arens A, Weichert W, Brand K, Koch M, Weitz J, Schmidt M, von Kalle C,  Glimm H. (2011) Distinct types of tumor-initiating cells form human colon cancer tumors and metastases

Cell Stem Cell.  9(4):357-65. (IF:25.94)

 

Ozretic L, Rhiem K, Huss S, Wappenschmidt B, Markiefka B, Sinn P, Schmutzler RK, Buettner R. (2011) High Nuclear Poly (Adenosine Diphosphate-Ribose) Polymerase Expression Is Predictive for BRCA1- and BRCA2-Deficient Breast Cancer.

J Clin Oncol. 29(34):4586-8. (IF:18.97) 

 

Danckwardt S, Gantzert AS, Macher-Goeppinger S, Probst HC, Gentzel M, Wilm M, Grone HJ, Schirmacher P, Hentze MW, Kulozik AE. (2011) p38 MAPK controls prothrombin expression by regulated RNA 3' end processing

Mol Cell. 41(3):298-310. (IF:14.19)

 

 

 


 

2010 


First and Senior Authorship 

 

Goeppert B, Schmezer P, Dutruel C, Oakes C, Renner MBreinig MWarth A, Vogel MN, Mittelbronn M, Mehrabi A, Gdynia GPenzel RLongerich TBreuhahn K, Popanda O, Plass C, Schirmacher PKern MA. (2010)
Down-regulation of tumor suppressor a kinase anchor protein 12 in human hepatocarcinogenesis by epigenetic mechanisms. 

Hepatology. 52(6):2023-33.(IF:10.84)
 
Pellegrino R, Calvisi DF, Ladu S, Ehemann V, Staniscia T, Evert M, Dombrowski F, Schirmacher PLongerich T. (2010)
Oncogenic and tumor suppressive roles of polo-like kinases in human hepatocellular carcinoma. 

Hepatology. 51(3):857-68. (IF:10.84)
 
Gdynia GKeith MKopitz J, Bergmann MFassl A, Weber AN, George J, Kees T, Zentgraf HW, Wiestler OD, Schirmacher PRoth W. (2010)
danger signaling protein HMGB1 induces a distinct form of cell death accompanied by formation of giant mitochondria.

Cancer Res. 70(21):8558-68. (IF:7.54)
 
Andrulis MCapper DMeyer JPenzel RHartmann C, Zentgraf H, von Deimling A. (2010)
IDH1 R132H mutation is a rare event in MPN as determined by a mutation specific antibody.

Haematologica. 95(10):1797-8. (IF:6.42)
 
Böck BCTagscherer KEFassl AKrämer AOehme I, Zentgraf HW, Keith MRoth W. (2010)
The PEA-15 protein regulates autophagy via activation of JNK.

J Biol Chem. 285(28):21644-54. (IF:5.33)
 
Cooperative Contribution 


Surolia I, Pirnie SP, Chellappa V, Taylor KN, Cariappa A, Moya J, Liu H, Bell DW, Driscoll DR, Diederichs S, Haider K, Netravali I, Le S, Elia R, Dow E, Lee A, Freudenberg J, De Jager PL, Chretien Y, Varki A, Macdonald ME, Gillis T, Behrens TW, Bloch D, Collier D, Korzenik J, Podolsky DK, Hafler D, Murali M, Sands B, Stone JH, Gregersen PK, Pillai S. (2010)
Functionally defective germline variants of sialic acid acetylesterase in autoimmunity.

Nature. 466(7303):243-7. (IF:34.48)
 
Stolz A, Ertych N, Kienitz A, Vogel C, Schneider V, Fritz B, Jacob R, Dittmar G, Weichert W, Petersen I, Bastians H. (2010)
The CHK2-BRCA1 tumour suppressor pathway ensures chromosomal stability in human somatic cells. 

Nat Cell Biol. 12(5):492-9. (IF:19.53)
 
 
 

Feurle GE, Moos V, Schinnerling K, Geelhaar A, Allers K, Biagi F, Bläker H, Moter A, Loddenkemper C, Jansen A, Schneider T. (2010)
The immune reconstitution inflammatory syndrome in whipple disease: a cohort study. 

Ann Intern Med. 153(11):710-7. (IF:16.23)
 
Kossatz U, Breuhahn K, Wolf B, Hardtke-Wolenski M, Wilkens L, Steinemann D, Singer S, Brass F, Kubicka S, Schlegelberger B, Schirmacher P, Manns MP, Singer JD, Malek NP. 
(2010)
The cyclin E regulator cullin 3 prevents mouse hepatic progenitor cells from becoming tumor-initiating cells. 

J Clin Invest. 120(11):3820-33. (IF:15.39)
 
Chalaris A, Adam N, Sina C, Rosenstiel P, Lehmann-Koch JSchirmacher P, Hartmann D, Cichy J, Gavrilova O, Schreiber S, Jostock T, Matthews V, Häsler R, Becker C, Neurath MF, Reiß K, Saftig P, Scheller J, Rose-John S. (2010)
Critical role of the disintegrin metalloprotease ADAM17 for intestinal inflammation and regeneration in mice.

 

 


 

2009

 

First and Senior Authorship

 

Breinig M, Caldas-Lopes E, Goeppert B, Malz M, Rieker R, Bergmann F, Schirmacher P, Mayer M, Chiosis G, Kern MA. (2009)

Targeting heat shock protein 90 with non-quinone inhibitors: A novel chemotherapeutic approach in human hepatocellular carcinoma.

Hepatology. 50(1):102-112. (IF:11.36)

 

Malz M, Weber A, Singer S, Riehmer V, Bissinger M, Riener MO, Longerich T, Soll C, Vogel A, Angel P, Schirmacher P, Breuhahn K. (2009)

Overexpression of far upstream element binding proteins: A mechanism regulating proliferation and migration in liver cancer cells.

Hepatology. 50(4):1130-9. (IF:11.36)

 

Funke B, Autschbach F, Kim S, Lasitschka F, Strauch U, Rogler G, Gdynia G, Li L, Gretz N, Macher-Goeppinger S, Sido B, Schirmacher P, Meuer SC, Roth W. (2009)

Functional characterisation of decoy receptor 3 in Crohn's disease.

Gut. 58(4):483-91. (IF:9.77)

 

Singer S, Malz M, Herpel E, Warth A, Bissinger M, Keith M, Muley T, Meister M, Hoffmann H, Penzel R, Gdynia G, Ehemann V, Schnabel PA, Kuner R, Huber P, Schirmacher P, Breuhahn K. (2009)

Coordinated Expression of Stathmin Family Members by Far Upstream Sequence Element-Binding Protein-1 Increases Motility in Non-Small Cell Lung Cancer.

Cancer Res. 69(6):2234-43. (IF:7.51)

 

Macher-Goeppinger S, Aulmann S, Tagscherer KE, Wagener N, Haferkamp A, Penzel R, Brauckhoff A, Hohenfellner M, Sykora J, Walczak H, Teh BT, Autschbach F, Herpel E, Schirmacher P, Roth W. (2009)

Prognostic value of tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) and TRAIL receptors in renal cell cancer.

Clin Cancer Res. 15(2):650-9. (IF:6.49)

 

Cooperative Contribution

 

Begus-Nahrmann Y, Lechel A, Obenauf AC, Nalapareddy K, Peit E, Hoffmann E, Schlaudraff F, Liss B, Schirmacher P, Kestler H, Danenberg E, Barker N, Clevers H, Speicher MR, Rudolph KL. (2009)

p53 deletion impairs clearance of chromosomal-instable stem cells in aging telomere-dysfunctional mice.

Nat Genet. 41(10):1138-43. (IF:30.26)

 

Schmitz R, Hansmann ML, Bohle V, Martin-Subero JI, Hartmann S, Mechtersheimer G, Klapper W, Vater I, Giefing M, Gesk S, Stanelle J, Siebert R, Küppers R. (2009)

TNFAIP3 (A20) is a tumor suppressor gene in Hodgkin lymphoma and primary mediastinal B cell lymphoma.

J Exp Med. 206(5):981-9. (IF:15.46)

 

Ceyhan GO, Bergmann F, Kadihasanoglu M, Altintas B, Demir IE, Hinz U, Müller MW, Giese T, Büchler MW, Giese NA, Friess H. (2009)

Pancreatic neuropathy and neuropathic pain-a comprehensive pathomorphological study of 546 cases.

Gastroenterology. 136(1):177-186. (IF:12.59)

 

Fortunato F, Bürgers H, Bergmann FRieger P, Büchler MW, Kroemer G, Werner J. (2009)

Impaired autolysosome formation correlates with Lamp-2 depletion: role of apoptosis, autophagy, and necrosis in pancreatitis.

Gastroenterology. 137(1):350-60. (IF:12.59) 

 

Németh J, Stein I, Haag D, Riehl A, Longerich T, Horwitz E, Breuhahn K, Gebhardt C, Schirmacher P, Hahn M, Ben-Neriah Y, Pikarsky E, Angel P, Hess J. (2009)

S100A8 and S100A9 are novel nuclear factor kappa B target genes during malignant progression of murine and human liver carcinogenesis.

Hepatology. 50(4):1130-9. (IF:11.36)

 


 

2008

 

First and Senior Authorship

 

Sido B, Lasitschka F, Giese T, Gassler N, Funke B, Schröder-Braunstein J, Brunnemer U, Meuer SC, Autschbach F. (2008)

A prominent role for mucosal cystine/cysteine metabolism in intestinal immunoregulation.

Gastroenterology.134(1):179-91. (IF: 11.67)

 

Nussbaum T, Samarin J, Ehemann V, Bissinger M, Ryschich E, Khamidjanov A, Yu X, Gretz N, Schirmacher P, Breuhahn K. (2008) 

Autocrine insulin-like growth factor-II stimulation of tumor cell migration is a progression step in human hepatocarcinogenesis.

Hepatology. 48(1):146-56. (IF: 10.73)

Straub BK, Stoeffel P, Heid H, Zimbelmann R, Schirmacher P. (2008) 

Differential pattern of lipid droplet-associated proteins and de novo perilipin expression in hepatocyte steatogenesis.

Hepatology. 47(6):1936-46. (IF: 10.73)

Schlaeger C, *Longerich T*, Schiller C, Bewerunge P, Mehrabi A, Toedt G, Kleeff J, Ehemann V, Eils R, Lichter P, Schirmacher P, Radlwimmer B. (2008)

Etiology-dependent molecular mechanisms in human hepatocarcinogenesis.

Hepatology. 47(2):511-520.  (IF: 10.73)  

* Equal Contribution*

 

Rabkin R, Awwad I, Chen Y, Ashley EA, Sun D, Sood S, Clusin W, Heidenreich P, Piecha G, Gross ML. (2008) 

Low-dose growth hormone is cardioprotective in uremia.

J Am Soc Nephrol. 19(9):1774-83. (IF: 7.1)

Cooperative Contribution

 
Zender L, Xue W, Zuber J, Semighini CP, Krasnitz A, Ma B, Zender P, Kubicka S, Luk JM, Schirmacher P, McCombie WR, Wigler M, Hicks J, Hannon GJ, Powers S,  (2008) 

Lowe SW. An oncogenomics-based in vivo RNAi screen identifies tumor suppressors in liver cancer.

Cell. 135(5):852-64. (IF: 29.9)


Xue W, Krasnitz A, Lucito R, Sordella R, Vanaelst L, Cordon-Cardo C, Singer S, Kuehnel F, Wigler M, Powers S, Zender L, Lowe SW. (2008) 

Genes Dev. 22(11):1439-44. (IF: 14.8)


Andrassy M, Volz HC, Igwe JC, Funke B, Eichberger SN, Kaya Z, Buss S, Autschbach F, Pleger ST, Lukic IK, Bea F, Hardt SE, Humpert PM, Bianchi ME, Mairbäurl H, Nawroth PP, Remppis A, Katus HA, Bierhaus A. (2008) 

Circulation. 117(25):3216-26. (IF: 12.8)

 

Zöllinger A, Stühmer T, Chatterjee M, Gattenlöhner S, Haralambieva E, Müller-Hermelink HK, Andrulis MGreiner A, Wesemeier C, Rath JC, Einsele H, Bargou RC. (2008) 

Blood. 112(8):3403-11. (IF: 10.9)

 

Gotthardt D, Runz H, Keitel V, Fischer C, Flechtenmacher C, Wirtenberger M, Weiss KH, Imparato S, Braun A, Hemminki K, Stremmel W, Rüschendorf F, Stiehl A, Kubitz R, Burwinkel B, Schirmacher P, Knisely AS, Zschocke J, Sauer P. (2008) 

Hepatology. 48(4):1157-66. (IF: 10.73)
 
 

 


 

2007

First and Senior Authorship
 
Gassler N, Roth W, Funke B, Schneider A, Herzog F, Tischendorf JJ, Grund K, Penzel R, Bravo IG, Mariadason J, Ehemann V, Sykora J, Haas TL, Walczak H, Ganten T, Zentgraf H, Erb P, Alonso A, Autschbach F, Schirmacher P, Knüchel R, Kopitz J. (2007)
Regulation of enterocyte apoptosis by acyl-CoA synthetase 5 splicing. 
Gastroenterology. 133(2):587-98. (IF:12.46)
Singer S, Ehemann V, Brauckhoff A, Keith M, Vreden S, Schirmacher P, Breuhahn K. (2007)
Protumorigenic overexpression of stathmin/Op18 by gain-of-function mutation in p53 in human hepatocarcinogenesis. 
Hepatology. 46(3):759-68. (IF:10.45)
 
Breinig M, Schirmacher P, Kern MA. (2007)

Cyclooxygenase-2 (COX-2) - a therapeutic target in liver cancer?

Curr Pharm Des. 13(32):3305-15. (IF:5.27)

 

Esposito I, Kayed H, Keleg S, Giese T, Sage EH, Schirmacher P, Friess H, Kleeff J. (2007)

Tumor-suppressor function of SPARC-like protein 1/Hevin in pancreatic cancer.
Neoplasia. 9(1):8-17. (IF:4.91)  

 

Gdynia G, Grund K, Eckert A, Böck BC, Funke B, Macher-Goeppinger S, Sieber S, Herold-Mende C, Wiestler B, Wiestler OD, Roth W. (2007)

Basal caspase activity promotes migration and invasiveness in glioblastoma cells.

Mol Cancer Res. 5(12):1232-40. (IF:4.76)
 
 Cooperative Contribution
 
Schaetzlein S, Kodandaramireddy NR, Ju Z, Lechel A, Stepczynska A, Lilli DR, Clark AB, Rudolph C, Kuhnel F, Wei K, Schlegelberger B, Schirmacher P, Kunkel TA, Greenberg RA, Edelmann W, Rudolph KL. (2007)
Exonuclease-1 deletion impairs DNA damage signaling and prolongs lifespan of telomere-dysfunctional mice. 
Cell. 130(5):863-77. (IF:29.19)
 
Choudhury AR, Ju Z, Djojosubroto MW, Schienke A, Lechel A, Schaetzlein S, Jiang H, Stepczynska A, Wang C, Buer J, Lee HW, von Zglinicki T, Ganser A, Schirmacher P, Nakauchi H, Rudolph KL. (2007)
Cdkn1a deletion improves stem cell function and lifespan of mice with dysfunctional telomeres without accelerating cancer formation. 
Nat Genet. 39(1):99-105. (IF:24.18)
 
Renner M, Bergmann G, Krebs I, End C, Lyer S, Hilberg F, Helmke B, Gassler N, Autschbach F, Bikker F, Strobel-Freidekind O, Gronert-Sum S, Benner A, Blaich S, Wittig R, Hudler M, Ligtenberg AJ, Madsen J, Holmskov U, Annese V, Latiano A, Schirmacher P, Amerongen AV, D'Amato M, Kioschis P, Hafner M, Poustka A, Mollenhauer J. (2007)
DMBT1 confers mucosal protection in vivo and a deletion variant is associated with Crohn's disease. Gastroenterology. 133(5):1499-509. (IF:12.46) 
 
Protzer U, Seyfried S, Quasdorff M, Sass G, Svorcova M, Webb D, Bohne F, Hösel M, Schirmacher P, Tiegs G. (2007)
Antiviral activity and hepatoprotection by heme oxygenase-1 in hepatitis B virus infection. Gastroenterology. 133(4):1156-65. (IF:12.46)



Lechel A, Holstege H, Begus Y, Schienke A, Kamino K, Lehmann U, Kubicka S, Schirmacher P, Jonkers J, Rudolph KL. (2007)
Telomerase deletion limits progression of p53-mutant hepatocellular carcinoma with short telomeres in chronic liver disease. 
Gastroenterology. 132(4):1465-75.  (IF:12.46)

 


 

2006

First and Senior Authorship
 
Müller-Decker K, Fürstenberger G, Annan N, Kucher D, Pohl-Arnold A, Steinbauer B, Esposito I, Chiblak S, Friess H, Schirmacher P, Berger I. (2006)
Preinvasive duct-derived neoplasms in pancreas of keratin 5-promoter cyclooxygenase-2 transgenic mice. 
Gastroenterology. 130(7):2165-78. (IF:12.39 )
 
Gassler N, Newrzella D, Böhm C, Lyer S, Li L, Sorgenfrei O, van Laer L, Sido B, Mollenhauer J, Poustka A, Schirmacher P, Gretz N. (2006)
Molecular characterisation of non-absorptive and absorptive enterocytes in human small intestine. 
Gut. 55(8):1084-9. (IF:7.69)
 
Kern MA, Haugg AM
, Koch AF, Schilling T, Breuhahn K, Walczak H, Fleischer B, Trautwein C, Michalski C, Schulze-Bergkamen H, Friess H, Stremmel W, Krammer PH, Schirmacher P, Müller M. (2006)
Cyclooxygenase-2 inhibition induces apoptosis signaling via death receptors and mitochondria in hepatocellular carcinoma. 
Cancer Res. 66(14):7059-66. (IF:7.61)
 
Finis K, Sültmann H, Ruschhaupt M, Buness A, Helmchen B, Kuner R, Gross ML, Fink B, Schirmacher P, Poustka A, Berger I. (2006)
Analysis of pigmented villonodular synovitis with genome-wide complementary DNA microarray and tissue array technology reveals insight into potential novel therapeutic approaches. 
Arthritis Rheum. 54(3):1009-19. (IF:7.42)
 
Breuhahn K, Longerich T, Schirmacher P.
 (2006)
Dysregulation of growth factor signaling in human hepatocellular carcinoma. 
Oncogene. 25(27):3787-800. (IF:6.87)
 
 Cooperative Contribution

 
Thuerigen O, Schneeweiss A, Toedt G, Warnat P, Hahn M, Kramer H, Brors B, Rudlowski C, Benner A, Schuetz F, Tews B, Eils R, Sinn HP, Sohn C, Lichter P. (2006)
Gene expression signature predicting pathologic complete response with gemcitabine, epirubicin, and docetaxel in primary breast cancer. 
J Clin Oncol. 24(12):1839-45. (IF:11.81)
 
 

Lenze D, Berg E, Volkmer-Engert R, Weiser AA, Greiner A, Knörr-Wittmann C, Anagnostopoulos I, Stein H, Hummel M. (2006)
Influence of antigen on the development of MALT lymphoma. 
Blood.107(3):1141-8. (IF:10.13)
 
 

Wursthorn K, Lutgehetmann M, Dandri M, Volz T, Buggisch P, Zollner B, Longerich T, Schirmacher P, Metzler F, Zankel M, Fischer C, Currie G, Brosgart C, Petersen J. (2006)
Peginterferon alpha-2b plus adefovir induce strong cccDNA decline and HBsAg reduction in patients with chronic hepatitis B. 
Hepatology.44(3):675-84. (IF:9.79)
 
Wenger T, Mattern J, Penzel R, Gassler N, Haas TL, Sprick MR, Walczak H, Krammer PH, Debatin KM, Herr I. (2006)
Specific resistance upon lentiviral TRAIL transfer by intracellular retention of TRAIL receptors. 
Cell Death Differ.13(10):1740-51. (IF:7.79)
 
di Mola FF, Friess H, Köninger J, Selvaggi F, Esposito I, Büchler MW, di Sebastiano P. (2006)
Haemorrhoids and transient receptor potential vanilloid 1.
Gut. 55(11):1665-6.(IF:7.69)

 


 

2005

First and Senior Authorship
 
Gross ML, Amann K, Ritz E.(2005)
Nephron number and renal risk in hypertension and diabetes. 
J Am Soc Nephrol.16 Suppl 1:S27-9. (IF:6.64)
 
 

Autschbach F, Eisold S, Hinz U, Zinser S, Linnebacher M, Giese T, Löffler T, Büchler MW, Schmidt J.(2005)
High prevalence of Mycobacterium avium subspecies paratuberculosis IS900 DNA in gut tissues from individuals with Crohn's disease. 
Gut. 54(7):944-9. (IF:6.60)
 
Gassler N, Herr I, Schneider A, Penzel R, Langbein L, Schirmacher P, Kopitz J.(2005) Impaired expression of acyl-CoA synthetase 5 in sporadic colorectal adenocarcinomas. 
J Pathol. 207(3):295-300. (IF:5.33)
 
Gross ML, Ritz E, Korsch M, Adamczak M, Weckbach M, Mall G, Berger I, Hansen A, Amann K.(2005)
Effects of estrogens on cardiovascular structure in uninephrectomized SHRsp rats. 
Kidney Int.67(3):849-57. (IF:4.79)
 
Moinzadeh P, Breuhahn K, Stützer H, Schirmacher P.(2005)
Chromosome alterations in human hepatocellular carcinomas correlate with aetiology and histological grade-results of an explorative CGH meta-analysis. 
Br J Cancer. 92(5):935-41. (IF:3.74)
 
 Cooperative Contribution

 
Schneider A, Krüger C, Steigleder T, Weber D, Pitzer C, Laage R, Aronowski J, Maurer MH, Gassler N, Mier W, Hasselblatt M, Kollmar R, Schwab S, Sommer C, Bach A, Kuhn HG, Schäbitz WR.(2005)
The hematopoietic factor G-CSF is a neuronal ligand that counteracts programmed cell death and drives neurogenesis. 
J Clin Invest.115(8):2083-98. (IF:14.20)
 
Nessling M, Richter K, Schwaenen C, Roerig P, Wrobel G, Wessendorf S, Fritz B, Bentz M, Sinn HP, Radlwimmer B, Lichter P.(2005)
Candidate genes in breast cancer revealed by microarray-based comparative genomic hybridization of archived tissue. 
Cancer Res.65(2):439-47. (IF:7.69)
 
Veltkamp C, Sartor RB, Giese T, Autschbach F, Kaden I, Veltkamp R, Rost D, Kallinowski B, Stremmel W.(2005) 
Regulatory CD4+CD25+ cells reverse imbalances in the T cell pool of bone marrow transplanted TGepsilon26 mice leading to the prevention of colitis. 
Gut.54(2):207-14. (IF:6.60)
 
Sträter J, Hinz U, Hasel C, Bhanot U, Mechtersheimer G, Lehnert T, Möller P.(2005)
Impaired CD95 expression predisposes for recurrence in curatively resected colon carcinoma: clinical evidence for immunoselection and CD95L mediated control of minimal residual disease. 
Gut.54(5):661-5. (IF:6.60)
 
Stremmel W, Merle U, Zahn A, Autschbach F, Hinz U, Ehehalt R. (2005)
Retarded release phosphatidylcholine benefits patients with chronic active ulcerative colitis. Gut. 54(7):966-71. (IF:6.60)

 


 

2004

First and Senior Authorship
 
Helmke BM, Mollenhauer J, Herold-Mende C, Benner A, Thome M, Gassler N, Wahl W, Lyer S, Poustka A, Otto HF, Deichmann M.(2004) 
BRAF mutations distinguish anorectal from cutaneous melanoma at the molecular level. Gastroenterology. 127(6):1815-20. (IF:13.09) 
 
Breuhahn K, Vreden S
, Haddad R, Beckebaum S, Stippel D, Flemming P, Nussbaum T, Caselmann WH, Haab BB, Schirmacher P.(2004)
Molecular profiling of human hepatocellular carcinoma defines mutually exclusive interferon regulation and insulin-like growth factor II overexpression.
Cancer Res. 64(17):6058-64. (IF:7.69) 
 
Gross ML, Adamczak M, Rabe T, Harbi NA, Krtil J, Koch A, Hamar P, Amann K, Ritz E. (2004)
Beneficial Effects of Estrogens on Indices of Renal Damage in Uninephrectomized SHRsp Rats. 
J Am Soc Nephrol. 15(2):348-58. (IF:6.64) 
 
Kern MA, Schöneweiss MM, Sahi D, Bahlo M, Haugg AM, Kasper HU, Dienes HP, Käferstein H, Breuhahn K, Schirmacher P. (2004) 
Cyclooxygenase-2 inhibitors suppress the growth of human hepatocellular carcinoma implants in nude mice. 
Carcinogenesis. 25(7):1193-9. (IF:5.38) 

Gassler N
, Kopitz J, Tehrani A, Ottenwälder B, Schnölzer M, Kartenbeck J, Lyer S, Autschbach F, Poustka A, Otto HF, Mollenhauer J.(2004) 
Expression of acyl-CoA synthetase 5 reflects the state of villus architecture in human small intestine. 
J Pathol. 202(2):188-96. (IF:5.33)

 


 Cooperative Contribution
 
Jüngst C, Cheng B, Gehrke R, Schmitz V, Nischalke HD, Ramakers J, Schramel P, Schirmacher P, Sauerbruch T, Caselmann WH. (2004) 
Oxidative damage is increased in human liver tissue adjacent to hepatocellular carcinoma. Hepatology. 39(6):1663-72. (IF:10.42) 
 
Schwarzbach MH, Koesters R, Germann A, Mechtersheimer G, Geisbill J, Winkler S, Niedergethmann M, Ridder R, Buechler MW, von Knebel Doeberitz M, Willeke F.(2004) Comparable transforming capacities and differential gene expression patterns of variant FUS/CHOP fusion transcripts derived from soft tissue liposarcomas. 
Oncogene. 23(40):6798-805. (IF:6.32) 
 
Barth TF, Müller S, Pawlita M, Siebert R, Rother JU, Mechtersheimer G, Kitinya J, Bentz M, Möller P. (2004) 
Homogeneous immunophenotype and paucity of secondary genomic aberrations are distinctive features of endemic but not of sporadic Burkitt's lymphoma and diffuse large B-cell lymphoma with MYC rearrangement.
J Pathol. 203(4):940-5. (IF:5.33) 
 
Bosch FX, Ritter D, Enders C, Flechtenmacher C, Abel U, Dietz A, Hergenhahn M, Weidauer H. (2004) 
Head and neck tumor sites differ in prevalence and spectrum of p53 alterations but these have limited prognostic value. 
Int J Cancer.111(4):530-8. (IF:4.41) 
 
Mollenhauer J, Helmke B, Medina D, Bergmann G, Gassler N, Müller H, Lyer S, Diedrichs L, Renner M, Wittig R, Blaich S, Hamann U, Madsen J, Holmskov U, Bikker F, Ligtenberg A, Carlén A, Olsson J, 

 



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