Recent Publications

Ni Y, Sonnabend J, Seitz S, Urban S.

The preS2-domain of the Hepatitis B Virus (HBV) is dispensable for infectivity but serves a spacer function for L-protein-connected virus assembly

J Virol. 2010 Feb 3. [Epub ahead of print]

Urban S, Schulze A, Dandri M, Petersen J.

The replication cycle of hepatitis B virus

J Hepatol. 2010 Feb;52(2):282-4. Epub 2009 Nov 24. No abstract available.

Andreas Schulze, Alexa Schieck, Yi Ni, Walter Mier, and Stephan Urban

Fine mapping of the preS-sequence requirements for Hepatitis B Virus (HBV) large envelope protein mediated receptor interaction

J Virol. 2010 Feb;84(4):1989-2000. Epub 2009 Dec 9.

Simister P, Schmitt M, Geitmann M, Wicht O, Danielson UH, Klein R, Bressanelli S, Lohmann V.

Structural and functional analysis of hepatitis C virus strain JFH1 polymerase

J Virol. 2009 Nov;83(22):11989-95. Epub 2009 Sep 9.

Friebe P, Bartenschlager R.

Role of RNA structures in genome terminal sequences of the hepatitis C virus for replication and assembly.

J Virol. 2009 Nov;83(22):11989-95. Epub 2009 Sep 9.

Kaul A, Stauffer S, Berger C, Pertel T, Schmitt J, Kallis S, Zayas M, Lohmann V, Luban J, Bartenschlager R.

Essential role of cyclophilin A for hepatitis C virus replication and virus production and possible link to polyprotein cleavage kinetics.

PLoS Pathog. 2009 Aug;5(8):e1000546. Epub 2009 Aug 14. Erratum in: PLoS Pathog. 2009 Sep;5(9). doi: 10.1371/annotation/29dffb2a-5d37-4196-b166-b0b15bc2f3fd. Lopez, Margarita Zayas [corrected to Zayas, Margarita].

Kaderali L, Dazert E, Zeuge U, Frese M, Bartenschlager R.

Reconstructing signaling pathways from RNAi data using probabilistic Boolean threshold networks.

Bioinformatics. 2009 Sep 1;25(17):2229-35. Epub 2009 Jun 19.

Pietschmann T, Zayas M, Meuleman P, Long G, Appel N, Koutsoudakis G, Kallis S, Leroux-Roels G, Lohmann V, Bartenschlager R.

Production of infectious genotype 1b virus particles in cell culture and impairment by replication enhancing mutations.

PLoS Pathog. 2009 Jun;5(6):e1000475. Epub 2009 Jun 12.

Kaul A, Wörz I, Bartenschlager R.

Adaptation of the hepatitis C virus to cell culture.

Methods Mol Biol. 2009;510:361-72.

Welsch S, Miller S, Romero-Brey I, Merz A, Bleck CK, Walther P, Fuller SD, Antony C, Krijnse-Locker J, Bartenschlager R.

Composition and three-dimensional architecture of the dengue virus replication and assembly sites.

Cell Host Microbe. 2009 Apr 23;5(4):365-75.

Dazert E, Neumann-Haefelin C, Bressanelli S, Fitzmaurice K, Kort J, Timm J, McKiernan S, Kelleher D, Gruener N, Tavis JE, Rosen HR, Shaw J, Bowness P, Blum HE, Klenerman P, Bartenschlager R, Thimme R.

Loss of viral fitness and cross-recognition by CD8+ T cells limit HCV escape from a protective HLA-B27-restricted human immune response.

J Clin Invest. 2009 Feb;119(2):376-86. doi:10.1172/JCI36587. Epub 2009 Jan 12.

Vassilaki N, Friebe P, Meuleman P, Kallis S, Kaul A, Paranhos-Baccalà G, Leroux-Roels G, Mavromara P, Bartenschlager R.

Role of Hepatitis C Virus Core+1 Open Reading Frame and Core Cis-Acting RNA Elements in Viral RNA Translation and Replication.

J Virol. 2008 Dec

Jirasko V, Montserret R, Appel N, Janvier A, Eustachi L, Brohm C, Steinmann E, Pietschmann T, Penin F, Bartenschlager R.

Structural and functional characterization of non-structural protein 2 for its role in hepatitis C virus assembly.

J Biol Chem. 2008 Oct 17;283(42):28546-28562. Epub 2008 Jul 21.

Steinmann E, Brohm C, Kallis S, Bartenschlager R, Pietschmann T.

Efficient Trans-Encapsidation of Hepatitis C Virus RNAs into Infectious Virus-like Particles.

J Virol. 2008 Jul;82(14):7034-46. Epub 2008 May 14.

Urban S.