Research Group Grimm

We specialize in advancing human gene therapy through innovative gene delivery methods using parvoviruses like AAV and bocavirus.

We work on gene therapy with AAV i.e., non-pathogenic Adeno-associated viruses, which are the most promising and most versatile viral vector for therapeutic gene transfer and which we engineer using a large portfolio of technologies such as DNA shuffling, peptide display, DNA/RNA barcoding, high-throughput in vivo screening in small or large animals, single-cell (sc)RNA sequencing and targeting a variety of diseases including infection with SARS-CoV-2 (Covid-19), human immunodeficiency virus (HIV; AIDS), hepatitis viruses (HB/D/EV), or disorders of the muscle, liver, CNS, eye at our various locations in Heidelberg.

For more information about the Grimm Lab, please check out Website Grimm Lab