Publikationen

Dou Y, Tetik-Elsherbiny N, Gao R, Ren Y, Chen YW, Merbecks M, Setya A, Lityagina O, Wang Y, Chichelnitskiy E, Abouissa A, Wu CC, Barreto G, Potente M, Wieland T, Ola R, Grieshaber P, Loukanov T, Gorenflo M, Heineke J, Cordero J, Dobreva G. Endothelial RNF20 suppresses endothelial-to-mesenchymal transition and safeguards physiological angiocrine signaling to prevent congenital heart disease. Nat Commun. 2025 Oct 27;16(1):9480.

Grieshaber P, Schneller A, Fonseca-Escalante E, Farag M, Krey R, Czundel A, Jaschinski C, Karck M, Gorenflo M, Loukanov T. A Low-Cost Workflow to Generate Virtual and Physical Three-Dimensional Models of Cardiac Structures. World J Pediatr Congenit Heart Surg. 2025 Jan;16(1):107-113.

Farag M, Isern Hacker M, Grieshaber P, Fonseca Escalante E, Karck M, Arnold R, Gorenflo M, Loukanov T. A 27-Year Experience with Atrioventricular Septal Defect Correction. Thorac Cardiovasc Surg. 2025 Jan;73(S 03):e11-e20.

Killinger K, Riedel F, Fiedler MO, Müller T, Wallwiener M, Wallwiener S, Elsässer M, Weigand MA, Böckler D, Erhart P, Grieshaber P, Hackert T, Germann G, Scholz AS. Dilemma Diagnosis Between Pulmonary Embolism and Amniotic Fluid Embolism During First Stage of Labor-A Case Report. Clin Case Rep. 2024 Nov 15;12(11):e9579.

Krey R, Jakob M, Karck M, Arif R, Farag M. Male-female differences following concomitant coronary artery bypass grafting and aortic valve replacement surgery. ESC Heart Fail. 2024 Oct;11(5):2913-2923.

Grieshaber P, Jaschinski C, Farag M, Fonseca-Escalante E, Gorenflo M, Karck M, Loukanov T. Surgical Treatment of Atrial Septal Defects. Rev Cardiovasc Med. 2024 Sep 29;25(10):350.

Haney AC, Ochs A, Pribe-Wolferts R, Mereles D, Loukanov T, Gorenflo M, Frey N, André F. 2 Rare Syndromes in 1 Patient: Determining the Cause of Sudden Cardiac Arrest. JACC Case Rep. 2024 Sep 1;29(18):102549.

Farag M, Escalante EF, Czundel A, Steeg C, Shelton B, Krey R, Grieshaber P, Loukanov T. Aortic uncrossing of the left circumflex aorta. Multimed Man Cardiothorac Surg. 2024 Jul 9;2024.

Perfusion During Aortic Arch Surgery-Keep it Physiologic, Grieshaber P, Farag M, Fonseca-Escalante E, Loukanov T. World J Pediatr Congenit Heart Surg. 2024; 15(2): 251.

Möbius A, Grieshaber P, Turra J, Riesterer D, Zaradzki M, Soso P, Hatiboglu G, Hohenfellner M, Warnecke G, Tochtermann U. Cavoatrial hypernephroma resection on cardiopulmonary bypass: Mild/normo-versus moderate hypothermia. Perfusion. 2023 Nov;38(8):1644-1651.

Kremer J, Jahn J, Klein S, Farag M, Borst T, Karck M. Early versus Delayed Surgery in Patients with Left-Sided Infective Endocarditis and Stroke. J Cardiovasc Dev Dis. 2023 Aug 21;10(8):356.

Model-driven survival prediction after congenital heart surgery, Zürn C, Hübner D, Ziesenitz V, Höhn R, Schuler L, Schlange T, Gorenflo M, Kari F, Kroll J, Loukanov T, Klemm R, Stiller B. Interdiscip Cardiovasc Thorac Surg. 2023; 37(3): ivad089.

Impact of hybrid procedure on pulmonary arterial dimensions and right ventricular load after biventricular repair, Uhl S, Grieshaber P, Arnold R, Loukanov T, Gorenflo M. J Cardiothorac Surg. 2023; 18(1): 65.

Kremer J, Meinert ÉFRC, Farag M, Mueller F, Soethoff JP, Karck M, Schmack B, Meyer AL, Warnecke G. New Wound Management of Driveline Infections with Cold Atmospheric Plasma. J Cardiovasc Dev Dis. 2022 Nov 21;9(11):405.

Arif R, Warninck A, Farag M, Sommer W, Leuschner F, Frey N, Karck M, Warnecke G, Geis NA. Long-Term Patency of Venous Conduits Targeting the Right Coronary Artery System-Single Is Superior to Sequential bypass Grafting. J Cardiovasc Dev Dis. 2022 Aug 26;9(9):285.

Heer T, von Scheidt M, Boening A, Heyken C, Gusmini F, de Waha A, Kuna C, Fach A, Grothusen C, Oberhoffer M, Knosalla C, Walther T, Danner BC, Misfeld M, Wimmer-Greinecker G, Siepe M, Grubitzsch H, Joost A, Schaefer A, Conradi L, Cremer J, Hamm C, Lange R, Radke PW, Schulz R, Laufer G, Grieshaber P, Attmann T, Schmoeckel M, Meyer A, Ziegelhöffer T, Hambrecht R, Sandner SE, Kastrati A, Schunkert H, Zeymer U. Prognostic impact of secondary prevention after coronary artery bypass grafting-insights from the TiCAB trial. Eur J Cardiothorac Surg. 2022 Aug 3;62(3):ezac048.

Gökler J, Aliabadi-Zuckermann AZ, Kaider A, Ambardekar AV, Antretter H, Artemiou P, Bertolotti AM, Boeken U, Brossa V, Copeland H, Generosa Crespo-Leiro M, Eixerés-Esteve A, Epailly E, Farag M, Hulman M, Khush KK, Masetti M, Patel J, Ross HJ, Rudež I, Silvestry S, Suarez SM, Vest A, Zuckermann AO. Indications, Complications, and Outcomes of Cardiac Surgery After Heart Transplantation: Results From the Cash Study. Front Cardiovasc Med. 2022 Jun 9;10:879612.

Latus H, Stammermann J, Voges I, Waschulzik B, Gutberlet M, Diller GP, Schranz D, Ewert P, Beerbaum P, Kühne T, Sarikouch S; German Competence Network for Congenital Heart Defects Investigators *. Impact of Right Ventricular Pressure Load After Repair of Tetralogy of Fallot. J Am Heart Assoc. 2022 Apr 5;11(7):e022694.

Surgical Treatment Following Stent Angioplasty for High-Risk Neonates With Critical Coarctation of the Aorta, Grieshaber P, Merbecks M, Jaschinski C, Fonseca E, Arnold R, Karck M, Gorenflo M, Loukanov T. World J Pediatr Congenit Heart Surg. 2022; 13(4): 426-435.

Psychosocial Impact of Congenital Heart Diseases on Patients and Their Families: A Parent's Perspective, Jaschinski C, Knetsch V, Parzer P, Meyr J, Schroeder B, Fonseca E, Karck M, Kaess M, Loukanov T. World J Pediatr Congenit Heart Surg. 2022; 13(1): 9-15.

Beckmann A, Dittrich S, Arenz C, Krogmann ON, Horke A, Tengler A, Meyer R, Bauer UMM, Hofbeck M; German Quality Assurance / Competence Network for Congenital Heart Defects Investigators. German Registry for Cardiac Operations and Interventions in Patients with Congenital Heart Disease: Report 2020-Comprehensive Data from 6 Years of Experience. Thorac Cardiovasc Surg. 2021 Dec;69(S 03):e21-e31.

Al-Maisary S, Farag M, Te Gussinklo WH, Kremer J, Pleger ST, Leuschner F, Karck M, Szabo G, Arif R. Are Sutureless and Rapid-Deployment Aortic Valves a Serious Alternative to TA-TAVI? A Matched-Pairs Analysis. J Clin Med. 2021 Jul 12;10(14):3072.

Kreibich M, Kremer J, Vötsch A, Berger T, Farag M, Winkler A, Siepe M, Karck M, Beyersdorf F, Rylski B, Czerny M, Gottardi R. Multicentre experience with the frozen elephant trunk technique to treat penetrating aortic ulcers involving the aortic arch. Eur J Cardiothorac Surg. 2021 Jun 14;59(6):1238-1244.

German Registry for Cardiac Operations and Interventions in Patients with Congenital Heart Disease: Report 2020-Comprehensive Data from 6 Years of Experience, Beckmann A, Dittrich S, Arenz C, Krogmann O, Horke A, Tengler A, Meyer R, Bauer U, Hofbeck M; German Quality Assurance / Competence Network for Congenital Heart Defects Investigators. Thorac Cardiovasc Surg. 2021;69(S 03):e21-e31.

Kremer J, Farag M, Brcic A, Zubarevich A, Schamroth J, Kreusser MM, Karck M, Ruhparwar A, Schmack B. Temporary right ventricular circulatory support following right ventricular infarction: results of a groin-free approach. ESC Heart Fail. 2020 Oct;7(5):2853-2861.

Merbecks MB, Ziesenitz VC, Rubner T, Meier N, Klein B, Rauch H, Saur P, Ritz N, Loukanov T, Schmitt S, Gorenflo M. Intermediate monocytes exhibit higher levels of TLR2, TLR4 and CD64 early after congenital heart surgery. Cytokine. 2020 Sep;133:155153.

Erarslan-Uysal B, Kunz JB, Rausch T, Richter-Pechańska P, van Belzen IA, Frismantas V, Bornhauser B, Ordoñez-Rueada D, Paulsen M, Benes V, Stanulla M, Schrappe M, Cario G, Escherich G, Bakharevich K, Kirschner-Schwabe R, Eckert C, Loukanov T, Gorenflo M, Waszak SM, Bourquin JP, Muckenthaler MU, Korbel JO, Kulozik AE. Chromatin accessibility landscape of pediatric T-lymphoblastic leukemia and human T-cell precursors. EMBO Mol Med. 2020 Sep 7;12(9):e12104.

Depth of anesthesia by Narcotrend® and postoperative characteristics in children undergoing cardiac surgery under extracorporeal circulation: a retrospective comparison of two anesthetic regimens, Plaschke K, Weiskircher A, Benner L, Klein B, Loukanov T, Gorenflo M, Weigand M, Rauch H. Perfusion. 2020 Jul; 35(5): 427-435.

Diller GP, Orwat S, Vahle J, Bauer UMM, Urban A, Sarikouch S, Berger F, Beerbaum P, Baumgartner H; German Competence Network for Congenital Heart Defects Investigators. Prediction of prognosis in patients with tetralogy of Fallot based on deep learning imaging analysis. Heart. 2020 Jul;106(13):1007-1014.

Weidenmann V, Robinson NB, Rong LQ, Hameed I, Naik A, Morsi M, Grieshaber P, Böning A, Girardi LN, Gaudino M. Diagnostic dilemma of perioperative myocardial infarction after coronary artery bypass grafting: A review. Int J Surg. 2020 Jul;79:76-83.

Leidenberger T, Gordon Y, Farag M, Delles M, Fava Sanches A, Fink MA, Kallenbach K, Kauczor HU, Rengier F. Imaging-Based 4D Aortic Pressure Mapping in Marfan Syndrome Patients: A Matched Case-Control Study. Ann Thorac Surg. 2020 May;109(5):1434-1440.

A Wide Comparison of Techniques for Repair of PAPVCs: One Institution's 20-Year Experience, Jaschinski C , Cussigh C , Fonseca E, Bruckner T, Karck M, Loukanov T. Thorac Cardiovasc Surg. 2020; 68(01): 015-023.

Cor triatriatum sinister with left anomalous pulmonary venous return to innominate vein, Jaschinski C, Uzdenov M, Loukanov T. Cardiol Young. 2019; 29(3): 428-430.

Ventrikelseptumdefekt, Jaschinski C, Loukanov T. Z Herz- Thorax- Gefäßchir. 2018; 32(1): 2-6.

Atriumseptumdefekt, Jaschinski C, Loukanov T. Z Herz-Thorax-Gefäßchir. 2017; 31(1): 3-6.

Repair of an aorto-right ventricular tunnel in a newborn, Ziesenitz V, Gorenflo M, Loukanov T. Cardiol Young. 2016; 26(1): 147-8.

Hypoplastic left heart syndrome - unresolved issues, Arnold R, Loukanov T, Gorenflo M. Front Pediatr 2014; 10(2): 125.

Patent ductus arteriosus in preterm infants: benefits of early surgical closure. Fonseca E, Georgiev S, Gorenflo M, Loukanov T. Asian Cardiovascular and Thoracic Annals 2014; 22(4): 391-6.

Extracorporeal life support with an integrated left ventricular vent in children with a low cardiac output. Sandrio S, Springer W, Karck M, Gorenflo M, Weymann A, Ruhparwar A, Loukanov T. Cardiol Young. 2014; 24(4): 654-660.

Cyclooxygenase-2 expression in lung in patients with congenital heart malformations and pulmonary arterial hypertension. Loukanov T, Jaschinski C, Kirilov M, Klimpel H, Karck M, Gorenflo M. Thorac Cardiovasc Surg. 2013; 61(4): 307-11.

Temporary tricuspid valve detachment for ventricular septal defect closure: is it worth doing it? Weymann A, Georgiev S, Vogelsang C, Ivad A, Karck M, Gorenflo M, Loukanov T. Heart Surg Forum. 2013; 16(2): E99-102.

Results of using cardiopulmonary bypass for spinal cord protection during surgical repair of complex aortic coarctation. Sandrio S, Karck M, Gorenflo M, Loukanov T. Cardiol Young. 2014; 24(1): 113-9.

A Rare, Combined Cardiac and Hepatic Crossbow Injury. Weymann A, Sebening C. Ann Thorac Cardiovasc Surg. 2014; 20 Suppl: 813-5.

Plasma cyclic 3',5'-adenosine monophosphate in patients with elevated pulmonary pressure due to left-to-right shunt. Loukanov T, Takahashi H, Tonchev P, Gross J, Bettendorf M, Gorenflo M. Can J Cardiol. 2011; 27(4): 523.e25-9. 

Comparison of inhaled nitric oxide with aerosolized iloprost for treatment of pulmonary hypertension in children after cardiopulmonary bypass surgery. Loukanov T, Bucsenez D, Springer W, Sebening C, Rauch H, Roesch E, Karck M, Gorenflo M. Clin Res Cardiol. 2011; 100(7): 595-602.

Endothelial nitric oxide synthase gene polymorphism (Glu298Asp) and acute pulmonary hypertension post cardiopulmonary bypass in children with congenital cardiac diseases. Loukanov T, Hoss K, Tonchev P, Klimpel H, Arnold R, Sebening C, Karck M, Gorenflo M. Cardiol Young. 2011; 21(2): 161-9.

Animal models related to congenital heart disease and clinical research in pulmonary hypertension. Loukanov T, Geiger R, Agrawal R. Cardiology. 2010; 116(1): 18-25.

Management of adult patients with perioperative pulmonary hypertension: technical aspects and therapeutic options. Winterhalter M, Antoniou T, Loukanov T. Cardiology. 2010; 116(1): 3-9.

Long-term outcome after external tracheal stabilization due to congenital tracheal instability. Ley S, Loukanov T, Ley-Zaporozhan J, Springer W, Sebening C, Sommerburg O, Hagl S, Gorenflo M. Ann Thorac Surg. 2010; 89(3): 918-25.

Localization of cyclo-oxygenase-2 in human recurrent colorectal cancer. Loukanov Ts, Kirilov M, Fürstenberger G, Müller-Decker K. Clin Invest Med. 2010; 33(1): E22-9.

Expression and mutational status of PDGFR in thymic tumours. Meister M, Kahl P, Muley T, Morresi-Hauf A, Sebening C, Kern MA, Breinig M, Schnabel P, Dienemann H, Schirmacher P, Rieker RJ. Anticancer Res. 2009; 29(10): 4057-61.

The evolution of the pulmonary arterial sling syndrome, with particular reference to the need for reoperations because of untreated tracheal stenosis. Loukanov TS, Sebening C, Springer W, Hagl S, Karck M, Gorenflo M. Cardiol Young. 2009; 19(5): 446-50.

Endothelin-1 and asymmetric dimethylarginine in children with left-to-right shunt after intracardiac repair. Loukanov T, Arnold R, Gross J, Sebening C, Klimpel H, Eichhorn J, Hoss K, Ulmer HE, Kark M, Gorenflo M. Clin Res Cardiol. 2008; 97(6): 383-8.

Modified sliding tracheal plasty using the bridging bronchus for repair of long-segment tracheal stenosis. Hagl S, Sebening C, Springer W, Loukanov T. Ann Thorac Surg. 2008; 85(3): 1118-20.

Outcome after mechanical aortic valve replacement in children and young adults. Arnold R, Ley-Zaporozhan J, Ley S, Loukanov T, Sebening C, Kleber JB, Goebel B, Hagl S, Karck M, Gorenflo M. Ann Thorac Surg. 2008; 85(2): 604-10.

Replacement of valved right ventricular to pulmonary artery conduits: an observational study with focus on right ventricular geometry. Loukanov T, Sebening C, Springer W, Khalil M, Ulmer HE, Hagl S, Karck M, Gorenflo M. Clin Res Cardiol. 2008; 97(3): 169-75.

Surgical treatment of long-segment tracheal anomalies in infants and children. Loukanov T, Gorenflo M, Sebening C, Springer W, Eichhorn J, Ulmer H, Hagl S. Thorac Cardiovasc Surg. 2007; 55(6): 375-9.

Management of congenital tracheal stenosis in infancy. Loukanov T, Sebening C, Gorenflo M, Hagl S. Eur J Cardiothorac Surg. 2007; 31(2): 331.

Magnetic resonance blood flow measurements in the follow-up of pediatric patients with aortic coarctation - a re-evaluation. Eichhorn JG, Fink C, Delorme S, Hagl S, Kauczor HU, Ulmer HE. Int J Cardiol. 2006; 113(3): 291-8.

Late results after extended pulmonary artery reconstruction in the arterial switch operation. Ullmann MV, Gorenflo M, Bolenz C, Sebening C, Goetze M, Arnold R, Ulmer HE, Hagl S. Ann Thorac Surg. 2006; 81(6): 2259-66.

Anomalous connection of the right superior caval vein to the morphologically left atrium. Gorenflo M, Sebening C, Ulmer HE. Cardiol Young. 2006; 16(2): 184-6.

Right ventricular expression of extracellular matrix proteins, matrix-metalloproteinases, and their inhibitors over a period of 3 years after heart transplantation. Schupp DJ, Huck BP, Sykora J, Flechtenmacher C, Gorenflo M, Koch A, Sack FU, Haass M, Katus HA, Ulmer HE, Hagl S, Otto HF, Schnabel PA. Virchows Arch. 2006; 448(2): 184-94.

Coronary fistula of right coronary artery to vena cava superior and ectasia of pulmonary artery. Koch A, Sebening C, DeSimone R, Jahn L, Sack FU, Hagl S. Z Kardiol. 2005; 94(12): 813-6.

Simultaneous management of congenital tracheal stenosis and cardiac anomalies in infants. Loukanov T, Sebening C, Springer W, Ulmer H, Hagl S. J Thorac Cardiovasc Surg. 2005; 130(6): 1537-41.

A case of pulmonary artery sling associated with long-segment funnel trachea and bronchus suis. Loukanov T, Sebening C, Springer W, Hagl S. Ann Thorac Surg. 2004; 78(5): 1839-42.

Ventricularization of the atrialized chamber: a concept of Ebstein's anomaly repair. Ullmann MV, Born S, Sebening C, Gorenflo M, Ulmer HE, Hagl S. Ann Thorac Surg. 2004; 78(3): 918-24; discussion 924-5.

Pathological changes of the myocardium in patients after atrial repair for transposition of the great arteries: a possible explanation for left ventricular dysfunction after secondary arterial switch. Gorenflo M, Serpi M, Schnabel PA, Hüging M, Schmidt KG, Hagl S, Ulmer HE. Z Kardiol. 2003; 92(9): 742-6.

Long-term results after repair of truncus arteriosus communis in neonates and infants. Ullmann MV, Gorenflo M, Sebening C, Ulmer HE, Hagl S. Thorac Cardiovasc Surg. 2003; 51(4): 175-9.

Long-term results after reconstruction of the left ventricular outflow tract by aortoventriculoplasty. Ullmann MV, Gorenflo M, Sebening C, Lange R, Jakob HG, Ulmer HE, Hagl S. Ann Thorac Surg. 2003; 75(1): 143-6.

The index of pulmonary vascular disease in children with congenital heart disease: relationship to clinical and haemodynamic findings. Gorenflo M, Ullmann M, Sebening C, Brockmeier K, Hagl S, Ulmer HE, Otto HF, Schnabel PA. Virchows Arch. 2002; 441(3): 264-70.

Myocardial bridging of the anterior interventricular coronary artery in the setting of hypertrophic cardiomyopathy in children and adolescents. Sebening C, Gorenflo M, Ulmer HE, Brockmeier K. Cardiol Young. 2002; 12(4): 414-6.

[Thrombolysis of prosthetic heart valve thrombosis using recombinant tissue plasminogen activator (rt-PA) in infancy and childhood]. Serpi M, Schmidt KG, Kreuz W, Bucsenez D, Springer W, Hagl S, Ulmer HE. Z Kardiol. 2001; 90(3): 191-6. German.

Vascular tracheobronchial compression syndromes-experience in surgical treatment and literature review. Sebening C, Jakob H, Tochtermann U, Lange R, Vahl CF, Bodegom P, Szabo G, Fleischer F, Schmidt K, Zilow E, Springer W, Ulmer HE, Hagl S. Thorac Cardiovasc Surg. 2000; 48(3): 164-74. Review.

CATCH 22 syndrome: report of 7 infants with follow-up data and review of the recent advancements in the genetic knowledge of the locus 22q11. Sergi C, Serpi M, Müller-Navia J, Schnabel PA, Hagl S, Otto HF, Ulmer HE. Pathologica. 1999; 91(3): 166-72. Review.

External stabilization of long-segment tracheobronchomalacia guided by intraoperative bronchoscopy. Hagl S, Jakob H, Sebening C, van Bodegom P, Schmidt K, Zilow E, Fleischer F, Ulmer H. Ann Thorac Surg. 1997; 64(5): 1412-20; discussion 1421.

Spinal cord protection using hypothermic cardiocirculatory arrest in extended repair of recoarctation and persistent hypoplastic aortic arch. Lange R, Thielmann M, Schmidt KG, Bauernschmitt R, Jakob H, Hasper B, Ulmer H, Hagl S. Eur J Cardiothorac Surg. 1997; 11(4): 697-702.