Scientists

The link between genetics and fertility disorders was found in 1959, when it was discovered that men having the so-called Klinefelter’s Syndrome had one X chromosome more (47,XXY) and women with Turner’s Syndrome had one X chromosome less (45,XO) in their karyptype. The molecular reasons of the fertility disruption related to these syndromes are still unknown. The only certain base is that the sex chromosomes X and Y must include genetic factors crucial to male and female fertility. Consequently, research today focuses mainly on studying the male and female fertility genes on the sex chromosomes X and Y.