Microbial, cognitive and psychophysiological changes in patients with irritable bowel syndrome

Summary

Irritable bowel syndrome (IBS) is a common functional gastrointestinal disease and affects about 11% of the adult population worldwide. Symptoms of irritable bowel syndrome can include abdominal pain, cramps, flatulence, diarrhea or constipation. Furthermore, IBS is often associated with psychopathological problems (such as an increased prevalence of anxiety or depressive diseases).  IBS is understood as a disorder of the microbiota-gut-brain axis, whereby the individual (active) factors are still unclear.

Our study aims to understand how these factors are related on an individual level. Therefore, we analyze microbiota, do psychophysiological tests and use questionnaire data.