Clinical medical physics in radiooncology

Our goal is to develop methods for high-precision irradiation of tumors within their three dimensional boundaries and at the same time spare the adjacent normal tissue as good as possible. To achieve this, the patient needs to be fixed precisely in the same position for each treatment fraction (session). The accuracy of patient positioning directly translates into the precision of the irradiation beam applied and thus the often required high doses needed to eradicate the tumor completely can be applied safely resulting in higher chances to cure the patient.

Du to constant progress in the field of radiotherapy we have today also the possibility

Computer scientists have developed radiotherapy planning software that allows to predict and to calculate the dose that will be deposited in the tissue prior to the irradiation. This also allows correction for inevitable motions of organs (such as breathing and heart beat) during the treatment.

Besides our duties in the clinical routine we are active in development and teaching in the following areas:


Implementation and development


Current projects

DHBW – bachelor theses
APMR – master theses   
Technische Universität Kaiserslautern – master theses

Selected publications

Dosimetriy:  Energy dosimetry

Rhein B, Hartmann G,  Bestimmung der Energiedosis in einem Medium dichter als Wasser bei 6MV Photonen mit einer zur Anzeige der Wasserenergiedosis kalibrierten Ionisationskammer. In: Tagungs CD 3 Ländertagung der ÖGMP, DGMP, SGSMP Wien  (2011) ISBN:3-925218-89-0.

Method for independent dose calculation for helical TomoTherapy

Klüter S, Schubert K, Lissner S, Sterzing F, Oetzel D, Debus J, Schlegel W, Oelfke W, Nill S (2014). Independent calculation of dose distributions for helical tomotherapy using a conventional treatment planning system. Medical Physics 41(8), 081709.

Integrated detector array for quality assurance of helical tomotherapy and develoment of a method to measure leave aperature

Lissner S, Schubert K, Klüter S, Oetzel D, Debus J (2013). A method for testing the performance and the accuracy of the binary MLC used in helical tomotherapy. Zeitschrift für Medizinische Physik 23, 153–161.

Peripheral doses in intensity modulated radiotherapy  (IMRT)

Lissner S, Schubert K, Wiezorek T, Sterzing F, Herfarth K, Sroka-Perez G, Debus J (2013). Investigations of peripheral dose for helical tomotherapy. Zeitschrift für Medizinische Physik 23(4), 324-31.

Wiezorek T, Schwahofer A, Schubert K (2009). The influence of different IMRT techniques on the peripheral dose: a comparison between sMLM-IMRT and helical tomotherapy. Strahlentherapie und Onkologie 185(10), 696-702.

Optimization  and quality assurance of IMRT techniqes

Klüter S, Sroka-Perez G, Schubert K, Debus J (2011). Leakage of the Siemens 160 MLC multileaf collimator on a dual energy linear accelerator. Physics in Medicine and Biology 56(2), N29-37.

Schubert K, Rhein B, Seurig M, Klüter S, Oetzel D, Debus J (2014). QA for rotational treatment delivery using the Octavius 4D Phantom. In: S. Klöck. Medizinische Physik. 44th Joint Conference of the SSRMP, DGMP, ÖGMP, Dreiländertagung für Medizinische Physik, Zürich, 159-160.  

Megavolt-computer tomography (MVCT) data sets for treatment planning

Prokesch H, Ecker S, Splinter M, Lampe C, Klüter S, Schubert K, Ellerbrock M, Jäkel O (2014). Combined Photon and Particle Radiotherapy Based on Megavoltage CT Data. In: Proceedings to the 53 Annual Meeting for the Particle Therapy Cooperative Group (PTCOG) 8-14 June 2014. International Journal of Particle Therapy 1(2), 636.

Schubert K, Maric T, Nill S, Sroka-Perez G, Herfarth K, Oelfke U, Debus J (2011). Tomotherapy MVCT in 3D-Conformal Treatment Planning. Radiotherapy and Oncology 99, S583. ESTRO Meeting, London.

Klüter S, Schubert K, Lissner S, Debus J (2011). Evaluation Of The Impact Of CT Hounsfield Unit Calibration on Dose Calculation in Helical Tomotherapy. International Journal of Radiation Oncology Biology Physics 81(2), S848-S849, Proceedings of the ASTRO 53rd Annual Meeting.

Bringing helical TomoTherapy into clinical routine,  implementation and development of methods for quality assurance

Schubert K, Klueter S, Lissner S, Wester X, Sterzing F, Oetzel D, Debus J (2013). SU-E-T-151: Evaluation of the Ability of the Seven29 Array to Measure Jaw Speeds On a TomoTherapy-System. AAPM 55th Annual Meeting. Medical Physics 40, 238.

K. Schubert, K. Wagenknecht, S. Lissner, G. Sroka-Perez and J. Debus (2009). Imaging QA Program for Image Guided RadioTherapy (IGRT). In: World Congress on Medical Physics and Biomedical Engineering, Munich. Springer Verlag Berlin Heidelberg, 457-459.

Schubert K, Nicholas D, Francois P, Lisbona A, Schmidt R, Tomsej M, Wagenknecht K, Sroka-Perez G, Debus J (2008). International Comparison of time-resolved Measurements on Helical Tomotherapy. International Journal of Radiation Oncology Biology Physics 72(1), S663, Proceedings of the 50th Annual ASTRO Meeting.

Schubert K, Sroka-Perez G, Wagenknecht K, Caprile-Etchart P, Sterzing F, Debus J (2007). QA for dynamic aspects of helical tomotherapy treatment delivery. Radiotherapy and Oncology 84, S1. 9th Biennial ESTRO Meeting on physics and radiation technology for clinical radiotherapy, Barcelona.