AG Ruggieri
Selected Original Research Articles
Ruggieri A, Helm M, Chatel-Chaix L.
An epigenetic “extreme makeover”: the methylation of flaviviral RNA (and beyond).
2020. RNA Biol 18:1-13.
Eiermann N, Haneke K, Sun Z, Stoecklin G, Ruggieri A.
Dance with the devil: Stress granules and signaling in antiviral responses.
2020. Viruses 12(9), 984.
Haneke K, Schott J, Lindner D, Hollensen AK, Damgaard CK, Mongis C, Knop M, Palm W, Ruggieri A, Stoecklin G..
CDK1 couples proliferation with protein synthesis.
2020. J Cell Biol. 219(3): e201906147.
Brocard M, Iadevaia V, Klein P, Hall B, Lewis G, Lu J, Burke J, Willcocks M, Parker R, Goodfellow IG, Ruggieri A, Locker N.
Norovirus infection results in eIF2α-independent host translation shut-off and remodels the G3BP1 interactome evading stress granule formation.
2020. PLoS Pathog. 16(1):e1008250.
Ruggieri A, and Stoecklin G.
A Signal to Condense.
2019. Nat Chem Biol. 15(1):5-6.
Schult, P., Roth H., Adams, R.L., Mas, C., Imbert, L., Orlik, C., Ruggieri, A., Pyle, A.M., Lohmann, V. (2018). MicroRNA-122 amplifies hepatitis C virus translation by shaping the structure of the internal ribosomal entry site. Nat Commun. 9(1):2613.
Roth H, Magg V, Uch F, Mutz P, Klein P, Haneke K, Lohmann V, Bartenschlager R, Fackler OT, Locker N, Stoecklin G, Ruggieri A,
Flavivirus infection uncouples translation suppression from cellular stress responses.
2017. mBio 8(1):e02150-16.
Brocard, M., Ruggieri, A., Locker, N. (2017). m6A RNA methylation, a new hallmark in virus-host interactions. J Gen Virol. 98(9):2207-2214.
Cortese, M., Goellner, S., Acosta, E.G., Neufeldt, C.J., Oleksiuk, O., Lampe, M., Haselmann, U., Funaya, C., Schieber, N., Ronchi, P., Schorb, M., Pruunsild, P., Schwab, Y., Chatel-Chaix, L., Ruggieri, A., Bartenschlager, R. (2017). Ultrastructural characterization of Zika virus replication factories. Cell Reports 18(9): 2113–2123.
Trautz, B., Wiedemann, H., Lüchtenborg, C., Pierini, V., Kranich, J., Glass, B., Kräusslich, H.-G., Brocker, T., Pizzato, M., Ruggieri, A., Brügger, B., Fackler, O.T. (2017). The host-cell restriction factor SERINC5 restricts HIV-1 infectivity without altering the lipid composition and organization of viral particles. J Biol Chem 292(33):13702-13713.
Trotart, M., Tsopoulidis, N., Tibroni, N., Willemsen, J., Binder, M., Ruggieri, A., Fackler, O.T. (2015). Sensing of HIV-1 infection in Tzm-bl cells with reconstituted expression of STING. J Virol. 90(4):2064-76.
Schmid, B., Rinas, M., Ruggieri, A., Reuter, A., Fischl, W., Harder, N., Bergeest, J.-P., Flossdorf, M., Rohr, K., Höfer, T., Bartenschlager, R. (2015). Live-cell analysis and modeling identify determinants of attenuation of Dengue virus 2-O-methyl mutant. PLoS Pathog. 11(12):e1005345.
Hiet, M.-S., Bauhofer, O., Zayas, M., Roth, H., Tanaka, Y., Schirmacher, P., Willemsen, J., Grünvogel, O., Bender, S., Binder, M., Lohmann, V., Lotteau, V., Ruggieri, A.†, Bartenschlager, R†. (2015). Control of temporal activation of hepatitis C virus-induced interferon response by domain 2 of nonstructural protein 5A. J Hepatol. 63(4):829-37.
Ruggieri A, Dazert E, Metz P, Hofmann S, Bergeest JP, Mazur J, Bankhead P, Hiet MS, Kallis S, Alvisi G, Samuel CE, Lohmann V, Kaderali L, Rohr K, Frese M, Stoecklin G, Bartenschlager R.
Dynamic oscillation of translation and stress granule formation mark the cellular response to virus infection.
Cell Host Microbe. 2012 Jul 19;12(1):71-85.