Department of Neurology… Research Neuroimmunology Molecular… Baló's concentric…


Baló`s concentric sclerosis: Diagnosis, prognosis and immunopathology


Principal investigators: Sven Jarius, Brigitte Wildemann 



Baló's concentric sclerosis (BCS) is an inflammatory disease of the central nervous system characterized by concentric rings of demyelination. Our work focuses on investigating potential differences in immunopathogenesis, treatment and outcome between BCS and conventional multiple sclerosis (MS).





Selected publications

  • Jarius S, Würthwein C, Behrens JR, Wanner J, Haas J, Paul F, Wildemann B. Baló’s concentric sclerosis is immunologically distinct from multiple sclerosis: results from retrospective analysis of almost 150 lumbar punctures. J Neuroinflammation 2018 Jan 18;15(1):22 [FREE PDF].
  • Behrens JR, Wanner J, Kuchling J, Ostendorf L, Harms L, Ruprecht K, Niendorf T, Jarius S, Wildemann B, Gieß RM, Scheel M, Bellmann-Strobl J, Wuerfel J, Paul F, Sinnecker T. Baló’s concentric sclerosis versus multiple sclerosis lesions - a 7 Tesla MRI study. Annals of Clinical and Translational Neurology; in press.