ResSurge Aktuelles Publikationen

Li X, Hoogland AI, Small BJ, Crowder SL, Gonzalez BD, Oswald LB, Sleight AG, Nguyen N, Lorona NC, Damerell V, Komrokji KR, Mooney K, Playdon MC, Ulrich CM, Li CI, Shibata D, Toriola AT, Ose J, Peoples AR, Siegel EM, Bower JE, Schneider M, Gigic B, Figueiredo JC, and Jim HSL (2023). Trajectories and risk factors of fatigue following colorectal cancer diagnosis. Colorectal Dis.

Himbert C, Ose J, Gigic B, Viskochil R, Santuci K, Lin T, Ashworth A, Cohan JN, Scaife CL, Jedrzkiewicz J, Damerell V, Atkins KM, Gong J, Mutch MG, Bernadt C, Felder S, Sanchez J, Cohen SA, Krane MK, Hinkle N, Wood E, Peoples AR, Figueiredo JC, Toriola AT, Siegel EM, Li CI, Shibata D, Boucher K, Round JL, Ulrich AB, Schneider M, Huang LC, Hardikar S, and Ulrich CM (2023). Associations of combined physical activity and body mass index groups with colorectal cancer survival outcomes. BMC Cancer 23, 300.

Yu M, Carter KT, Baker KK, Redman MW, Wang T, Vickers K, Li CI, Cohen SA, Krane M, Ose J, Gigic B, Figueiredo JC, Toriola AT, Siegel EM, Shibata D, Schneider M, Ulrich CM, Dzubinski LA, Schoen RE, and Grady WM (2023). Elevated EVL methylation level in the normal colon mucosa is a potential risk biomarker for developing recurrent adenomas. Cancer Epidemiol Biomarkers Prev.

Ose J, Gigic B, Brezina S, Lin T, Peoples AR, Schobert PP, Baierl A, van Roekel E, Robinot N, Gicquiau A, Achaintre D, Scalbert A, van Duijnhoven FJB, Holowatyj AN, Gumpenberger T, Schrotz-King P, Ulrich AB, Ulvik A, Ueland PM, Weijenberg MP, Habermann N, Keski-Rahkonen P, Gsur A, Kok DE, and Ulrich CM (2023). Higher Plasma Creatinine Is Associated with an Increased Risk of Death in Patients with Non-Metastatic Rectal but Not Colon Cancer: Results from an International Cohort Consortium. Cancers (Basel) 15.

Zhang C, Al-Shaheri FN, Alhamdani MSS, Bauer AS, Hoheisel JD, Schenk M, Hinz U, Goedecke P, Al-Halabi K, Buchler MW, Giese NA, Hackert T, and Roth S (2023). Blood-Based Diagnosis and Risk Stratification of Patients with Pancreatic Intraductal Papillary Mucinous Neoplasm (IPMN). Clin Cancer Res 29, 1535-1545.

Yousuf S, Qiu M, Voith von Voithenberg L, Hulkkonen J, Macinkovic I, Schulz AR, Hartmann D, Mueller F, Mijatovic M, Ibberson D, AlHalabi KT, Hetzer J, Anders S, Brune B, Mei HE, Imbusch CD, Brors B, Heikenwalder M, Gaida MM, Buchler MW, Weigert A, Hackert T, and Roth S (2023). Spatially Resolved Multi-Omics Single-Cell Analyses Inform Mechanisms of Immune Dysfunction in Pancreatic Cancer. Gastroenterology.

Studier-Fischer A, Seidlitz S, Sellner J, Bressan M, Ozdemir B, Ayala L, Odenthal J, Knoedler S, Kowalewski KF, Haney CM, Salg G, Dietrich M, Kenngott H, Gockel I, Hackert T, Muller-Stich BP, Maier-Hein L, and Nickel F (2023). HeiPorSPECTRAL - the Heidelberg Porcine HyperSPECTRAL Imaging Dataset of 20 Physiological Organs. Sci Data 10, 414.

Lindley CL, Gigic B, Peoples AR, Han CJ, Lin T, Himbert C, Warby CA, Boehm J, Hardikar S, Ashworth A, Schneider M, Ulrich A, Schrotz-King P, Figueiredo JC, Li CI, Shibata D, Siegel EM, Toriola AT, Ulrich CM, Syrjala KL, and Ose J (2023). Pre-surgery inflammatory and angiogenesis biomarkers as predictors of 12-month cancer-related distress: Results from the ColoCare Study. Cancer Epidemiol Biomarkers Prev.

Campa D, Gentiluomo M, Stein A, Aoki MN, Oliverius M, Vodickova L, Jamroziak K, Theodoropoulos G, Pasquali C, Greenhalf W, Arcidiacono PG, Uzunoglu F, Pezzilli R, Luchini C, Puzzono M, Loos M, Giaccherini M, Katzke V, Mambrini A, Kiudeliene E, Federico KE, Johansen J, Hussein T, Mohelnikova-Duchonova B, van Eijck CHJ, Brenner H, Farinella R, Perez JS, Lovecek M, Buchler MW, Hlavac V, Izbicki JR, Hackert T, Chammas R, Zerbi A, Lawlor R, Felici A, Gotz M, Capurso G, Ginocchi L, Gazouli M, Kupcinskas J, Cavestro GM, Vodicka P, Moz S, Neoptolemos JP, Kunovsky L, Bojesen SE, Carrara S, Gioffreda D, Morkunas E, Abian O, Bunduc S, Basso D, Boggi U, Wlodarczyk B, Szentesi A, Vanella G, Chen I, Bijlsma MF, Kiudelis V, Landi S, Schottker B, Corradi C, Giese N, Kaaks R, Peduzzi G, Hegyi P, Morelli L, Furbetta N, Soucek P, Latiano A, Talar-Wojnarowska R, Lindgaard SC, Dijk F, Milanetto AC, Tavano F, Cervena K, Eross B, Testoni SG, Verhagen-Oldenampsen JHE, Malecka-Wojciesko E, Costello E, Salvia R, Maiello E, Ermini S, Sperti C, Holleczek B, Perri F, Skieceviciene J, Archibugi L, Lucchesi M, Rizzato C, and Canzian F (2023). The PANcreatic Disease ReseArch (PANDoRA) consortium: Ten years' experience of association studies to understand the genetic architecture of pancreatic cancer. Crit Rev Oncol Hematol 186, 104020.

Berghuijs K, Kaddas HK, Trujillo G, Rouhani G, Chevrier A, Ose J, Shibata D, Toriola AT, Figueiredo JC, Peoples AR, Li CI, Hardikar S, Siegel EM, Gigic B, Schneider M, Ulrich CM, and Kirchhoff AC (2023). Age-related differences in employment, insurance, and financial hardship among colorectal cancer patients: a report from the ColoCare Study. J Cancer Surviv.

Ahmed A, Kohler S, Klotz R, Giese N, Hackert T, Springfeld C, Jager D, and Halama N (2023). Sex Differences in the Systemic and Local Immune Response of Pancreatic Cancer Patients. Cancers (Basel) 15.

Zhang C, Al-Shaheri FN, Alhamdani MSS, Bauer AS, Hoheisel JD, Schenk M, Hinz U, Goedecke P, Al-Halabi K, Buchler MW, Giese NA, Hackert T, and Roth S (2022). Blood-based diagnosis and risk stratification of patients with pancreatic intraductal papillary mucinous neoplasm (IPMN). Clin Cancer Res.

Walle T, Kraske JA, Liao B, Lenoir B, Timke C, von Bohlen Und Halbach E, Tran F, Griebel P, Albrecht D, Ahmed A, Suarez-Carmona M, Jimenez-Sanchez A, Beikert T, Tietz-Dahlfuss A, Menevse AN, Schmidt G, Brom M, Pahl JHW, Antonopoulos W, Miller M, Perez RL, Bestvater F, Giese NA, Beckhove P, Rosenstiel P, Jager D, Strobel O, Pe'er D, Halama N, Debus J, Cerwenka A, and Huber PE (2022). Radiotherapy orchestrates natural killer cell dependent antitumor immune responses through CXCL8. Sci Adv 8, eabh4050.

Walle T, Kraske JA, Liao B, Lenoir B, Timke C, von Bohlen Und Halbach E, Tran F, Griebel P, Albrecht D, Ahmed A, Suarez-Carmona M, Jimenez-Sanchez A, Beikert T, Tietz-Dahlfuss A, Menevse AN, Schmidt G, Brom M, Pahl JHW, Antonopoulos W, Miller M, Perez RL, Bestvater F, Giese NA, Beckhove P, Rosenstiel P, Jager D, Strobel O, Pe'er D, Halama N, Debus J, Cerwenka A, and Huber PE (2022). Radiotherapy orchestrates natural killer cell dependent antitumor immune responses through CXCL8. Sci Adv 8, eabh4050.

Strowitzki MJ, Nelson R, Garcia MP, Tuffs C, Bleul MB, Fitzsimons S, Navas J, Uzieliene I, Ritter AS, Phelan D, Kierans SJ, Blanco A, Bernotiene E, Belton O, Schneider M, Cummins EP, and Taylor CT (2022). Carbon Dioxide Sensing by Immune Cells Occurs through Carbonic Anhydrase 2-Dependent Changes in Intracellular pH. J Immunol 208, 2363-2375.

Stewart KL, Gigic B, Himbert C, Warby CA, Ose J, Lin T, Schrotz-King P, Boehm J, Jordan KC, Metos J, Schneider M, Figueiredo JC, Li CI, Shibata D, Siegel E, Toriola AT, Hardikar S, and Ulrich CM (2022). Association of Sugar Intake with Inflammation- and Angiogenesis-Related Biomarkers in Newly Diagnosed Colorectal Cancer Patients. Nutr Cancer 74, 1636-1643.

Schuth S, Le Blanc S, Krieger TG, Jabs J, Schenk M, Giese NA, Buchler MW, Eils R, Conrad C, and Strobel O (2022). Patient-specific modeling of stroma-mediated chemoresistance of pancreatic cancer using a three-dimensional organoid-fibroblast co-culture system. J Exp Clin Cancer Res 41, 312.

Salg GA, Poisel E, Neulinger-Munoz M, Gerhardus J, Cebulla D, Bludszuweit-Philipp C, Vieira V, Nickel F, Herr I, Blaeser A, Giese NA, Hackert T, and Kenngott HG (2022). Toward 3D-bioprinting of an endocrine pancreas: A building-block concept for bioartificial insulin-secreting tissue. J Tissue Eng 13, 20417314221091033.

Ose J, Gigic B, Hardikar S, Lin T, Himbert C, Warby CA, Peoples AR, Lindley CL, Boehm J, Schrotz-King P, Figueiredo JC, Toriola AT, Siegel EM, Li CI, Ulrich A, Schneider M, Shibata D, and Ulrich CM (2022). Presurgery Adhesion Molecules and Angiogenesis Biomarkers Are Differently Associated with Outcomes in Colon and Rectal Cancer: Results from the ColoCare Study. Cancer Epidemiol Biomarkers Prev 31, 1650-1660.

Leinenkugel G, Kong B, Raulefs S, Miller K, Roth S, Jiang H, Istvanffy R, Heikenwalder H, Maeritz N, Regel I, Abiatari I, Kleeff J, Michalski CW, and Rieder S (2022). Sca-1 is a marker for cell plasticity in murine pancreatic epithelial cells and induced by IFN-beta in vitro. Pancreatology 22, 294-303.

Himbert C, Warby CA, Gigic B, Ose J, Lin T, Viskochil R, Peoples AR, Ashworth A, Schrotz-King P, Scaife CL, Cohan JN, Jedrzkiewicz J, Schirmacher P, Grady WM, Cohen SA, Krane M, Figueiredo JC, Toriola AT, Siegel EM, Shibata D, Round JL, Huang LC, Li CI, Schneider M, Ulrich A, Hardikar S, and Ulrich CM (2022). Associations of individual and combined physical activity and body mass index groups with pro-inflammatory biomarkers among colorectal cancer patients. Cancer Epidemiol Biomarkers Prev.

Himbert C, Stephens WZ, Gigic B, Hardikar S, Holowatyj AN, Lin T, Ose J, Swanson E, Ashworth A, Warby CA, Peoples AR, Nix D, Jedrzkiewicz J, Bronner M, Pickron B, Scaife C, Cohan JN, Schrotz-King P, Habermann N, Boehm J, Hullar M, Figueiredo JC, Toriola AT, Siegel EM, Li CI, Ulrich AB, Shibata D, Boucher K, Huang LC, Schneider M, Round JL, and Ulrich CM (2022). Differences in the gut microbiome by physical activity and BMI among colorectal cancer patients. Am J Cancer Res 12, 4789-4801.

Heger U, Martens A, Schillings L, Walter B, Hartmann D, Hinz U, Pausch T, Giese N, Michalski CW, and Hackert T (2022). Myofibroblastic CAF Density, Not Activated Stroma Index, Indicates Prognosis after Neoadjuvant Therapy of Pancreatic Carcinoma. Cancers (Basel) 14.

He L, Boulant S, Stanifer M, Guo C, Niessen A, Chen M, Felix K, Bergmann F, Strobel O, and Schimmack S (2022). The link between menin and pleiotrophin in the tumor biology of pancreatic neuroendocrine neoplasms. Cancer Sci 113, 1575-1586.

Harnoss JM, Cai J, Hinterkopf S, Radhakrishnan P, Schmitt A, Dupovac M, Nees LK, Strowitzki MJ, Taylor CT, and Schneider M (2022). Prolyl Hydroxylase Inhibition Mitigates Allograft Injury During Liver Transplantation. Transplantation 106, e430-e440.

Harnoss JM, Cai J, Hinterkopf S, Radhakrishnan P, Schmitt A, Dupovac M, Nees LK, Strowitzki MJ, Taylor CT, and Schneider M (2022). Prolyl Hydroxylase Inhibition Mitigates Allograft Injury During Liver Transplantation. Transplantation.

Gigic B, van Roekel E, Holowatyj AN, Brezina S, Geijsen A, Ulvik A, Ose J, Koole JL, Damerell V, Kiblawi R, Gumpenberger T, Lin T, Kvalheim G, Koelsch T, Kok DE, van Duijnhoven FJ, Bours MJ, Baierl A, Li CI, Grady W, Vickers K, Habermann N, Schneider M, Kampman E, Ueland PM, Ulrich A, Weijenberg M, Gsur A, Ulrich C, and Consortium F (2022). Cohort profile: Biomarkers related to folate-dependent one-carbon metabolism in colorectal cancer recurrence and survival - the FOCUS Consortium. BMJ Open 12, e062930.

Gentiluomo M, Capurso G, Morelli L, Ermini S, Pasquali C, Latiano A, Tavano F, Greenhalf W, Milanetto AC, Landi S, Roth S, Malecka-Wojciesko E, Costello E, Jamroziak K, Perri F, Boggi U, Basso D, Farinati F, Kaaks R, Vanella G, Gais Zurcher AJ, Archibugi L, Lawlor RT, Canzian F, and Campa D (2022). Genetically Determined Telomere Length Is Associated with Pancreatic Neuroendocrine Neoplasms Onset. Neuroendocrinology 112, 1168-1176.

Felix K, Honda K, Nagashima K, Kashiro A, Takeuchi K, Kobayashi T, Hinterkopf S, Gaida MM, Dang H, Brindl N, Kaiser J, Buchler MW, and Strobel O (2022). Noninvasive risk stratification of intraductal papillary mucinous neoplasia with malignant potential by serum apolipoprotein-A2-isoforms. Int J Cancer 150, 881-894.

Felix K, Honda K, Nagashima K, Kashiro A, Takeuchi K, Kobayashi T, Hinterkopf S, Gaida MM, Dang H, Brindl N, Kaiser J, Buchler MW, and Strobel O (2022). Noninvasive risk stratification of intraductal papillary mucinous neoplasia with malignant potential by serum apolipoprotein-A2-isoforms. Int J Cancer 150, 881-894.

Brindl N, Boekhoff H, Bauer AS, Gaida MM, Dang HT, Kaiser J, Hoheisel JD, and Felix K (2022). Use of Autoreactive Antibodies in Blood of Patients with Pancreatic Intraductal Papillary Mucinous Neoplasms (IPMN) for Grade Distinction and Detection of Malignancy. Cancers (Basel) 14.

Brindl N, Boekhoff H, Bauer AS, Gaida MM, Dang HT, Kaiser J, Hoheisel JD, and Felix K (2022). Use of Autoreactive Antibodies in Blood of Patients with Pancreatic Intraductal Papillary Mucinous Neoplasms (IPMN) for Grade Distinction and Detection of Malignancy. Cancers (Basel) 14.

Biller ML, Tuffs C, Bleul M, Tran DT, Dupovac M, Keppler U, Harnoss JM, Probst P, Schneider M, and Strowitzki MJ (2022). Effect of Metformin on HIF-1alpha Signaling and Postoperative Adhesion Formation. J Am Coll Surg 234, 1167-1180.

Ahmed A, Kohler S, Klotz R, Giese N, Hackert T, Springfeld C, Zornig I, Jager D, and Halama N (2022). Tertiary lymphoid structures and their association to immune phenotypes and circulatory IL2 levels in pancreatic ductal adenocarcinoma. Oncoimmunology 11, 2027148.31.          Ahmed A, Kohler S, Klotz R, Giese N, Hackert T, Springfeld C, Zornig I, Jager D, and Halama N (2022). Tertiary lymphoid structures and their association to immune phenotypes and circulatory IL2 levels in pancreatic ductal adenocarcinoma. Oncoimmunology 11, 2027148.

Ahmed A, Klotz R, Kohler S, Giese N, Hackert T, Springfeld C, Jager D, and Halama N (2022). Immune features of the peritumoral stroma in pancreatic ductal adenocarcinoma. Front Immunol 13, 947407.

Xu Z, Hu K, Bailey P, Springfeld C, Roth S, Kurilov R, Brors B, Gress T, Buchholz M, An J, Wei K, Peccerella T, Buchler MW, Hackert T, and Neoptolemos JP (2021). Clinical Impact of Molecular Subtyping of Pancreatic Cancer. Front Cell Dev Biol 9, 743908.

Wu Y, Kroller L, Miao B, Boekhoff H, Bauer AS, Buchler MW, Hackert T, Giese NA, Taipale J, and Hoheisel JD (2021). Promoter Hypermethylation Promotes the Binding of Transcription Factor NFATc1, Triggering Oncogenic Gene Activation in Pancreatic Cancer. Cancers (Basel) 13.

Strowitzki MJ, Kimmer G, Wehrmann J, Ritter AS, Radhakrishnan P, Opitz VM, Tuffs C, Biller M, Kugler J, Keppler U, Harnoss JM, Klose J, Schmidt T, Blanco A, Taylor CT, and Schneider M (2021). Inhibition of HIF-prolyl hydroxylases improves healing of intestinal anastomoses. JCI Insight 6.

Strowitzki MJ, Kimmer G, Wehrmann J, Ritter AS, Radhakrishnan P, Opitz VM, Tuffs C, Biller M, Kugler J, Keppler U, Harnoss JM, Klose J, Schmidt T, Blanco A, Taylor CT, and Schneider M (2021). Inhibition of HIF-prolyl hydroxylases improves healing of intestinal anastomoses. JCI Insight 6.

Roth S, and Hackert T (2021). [Influence of molecular pathology on oncological surgery of pancreatic cancer]. Chirurg 92, 975-980.

Roth S, Bose P, Alhamdani MSS, Mustafa SA, Tjaden C, Zamzow K, Hinz U, Michalski CW, Neoptolemos JP, Hoheisel JD, Buchler MW, and Hackert T (2021). Noninvasive Discrimination of Low and High-risk Pancreatic Intraductal Papillary Mucinous Neoplasms. Ann Surg 273, e273-e275.

Pfister D, Nunez NG, Pinyol R, Govaere O, Pinter M, Szydlowska M, Gupta R, Qiu M, Deczkowska A, Weiner A, Muller F, Sinha A, Friebel E, Engleitner T, Lenggenhager D, Moncsek A, Heide D, Stirm K, Kosla J, Kotsiliti E, Leone V, Dudek M, Yousuf S, Inverso D, Singh I, Teijeiro A, Castet F, Montironi C, Haber PK, Tiniakos D, Bedossa P, Cockell S, Younes R, Vacca M, Marra F, Schattenberg JM, Allison M, Bugianesi E, Ratziu V, Pressiani T, D'Alessio A, Personeni N, Rimassa L, Daly AK, Scheiner B, Pomej K, Kirstein MM, Vogel A, Peck-Radosavljevic M, Hucke F, Finkelmeier F, Waidmann O, Trojan J, Schulze K, Wege H, Koch S, Weinmann A, Bueter M, Rossler F, Siebenhuner A, De Dosso S, Mallm JP, Umansky V, Jugold M, Luedde T, Schietinger A, Schirmacher P, Emu B, Augustin HG, Billeter A, Muller-Stich B, Kikuchi H, Duda DG, Kutting F, Waldschmidt DT, Ebert MP, Rahbari N, Mei HE, Schulz AR, Ringelhan M, Malek N, Spahn S, Bitzer M, Ruiz de Galarreta M, Lujambio A, Dufour JF, Marron TU, Kaseb A, Kudo M, Huang YH, Djouder N, Wolter K, Zender L, Marche PN, Decaens T, Pinato DJ, Rad R, Mertens JC, Weber A, Unger K, Meissner F, Roth S, Jilkova ZM, Claassen M, Anstee QM, Amit I, Knolle P, Becher B, Llovet JM, and Heikenwalder M (2021). NASH limits anti-tumour surveillance in immunotherapy-treated HCC. Nature 592, 450-456.

Ose J, Gigic B, Brezina S, Lin T, Baierl A, Geijsen A, van Roekel E, Robinot N, Gicquiau A, Achaintre D, Keski-Rahkonen P, Duijnhoven F, Gumpenberger T, Holowatyj AN, Kok DE, Koole A, Schrotz-King P, Ulrich AB, Schneider M, Ulvik A, Ueland PM, Weijenberg MP, Habermann N, Scalbert A, Gsur A, and C MU (2021). Targeted Plasma Metabolic Profiles and Risk of Recurrence in Stage II and III Colorectal Cancer Patients: Results from an International Cohort Consortium. Metabolites 11.

Niessen A, Schimmack S, Sandini M, Fliegner D, Hinz U, Lewosinska M, Hackert T, Buchler MW, and Strobel O (2021). C-reactive protein independently predicts survival in pancreatic neuroendocrine neoplasms. Sci Rep 11, 23768.

Nienhuser H, Kim W, Malagola E, Ruan T, Valenti G, Middelhoff M, Bass A, Der CJ, Hayakawa Y, and Wang TC (2021). Mist1+ gastric isthmus stem cells are regulated by Wnt5a and expand in response to injury and inflammation in mice. Gut 70, 654-665.

Neulinger-Munoz M, Schaack D, Grekova SP, Bauer AS, Giese T, Salg GA, Espinet E, Leuchs B, Heller A, Nuesch JPF, Schenk M, Volkmar M, and Giese NA (2021). Human Retrotransposons and the Global Shutdown of Homeostatic Innate Immunity by Oncolytic Parvovirus H-1PV in Pancreatic Cancer. Viruses 13.

Lu Y, Corradi C, Gentiluomo M, Lopez de Maturana E, Theodoropoulos GE, Roth S, Maiello E, Morelli L, Archibugi L, Izbicki JR, Sarlos P, Kiudelis V, Oliverius M, Aoki MN, Vashist Y, van Eijck CHJ, Gazouli M, Talar-Wojnarowska R, Mambrini A, Pezzilli R, Bueno-de-Mesquita B, Hegyi P, Soucek P, Neoptolemos JP, Di Franco G, Sperti C, Kauffmann EF, Hlavac V, Uzunoglu FG, Ermini S, Malecka-Panas E, Lucchesi M, Vanella G, Dijk F, Mohelnikova-Duchonova B, Bambi F, Petrone MC, Jamroziak K, Guo F, Kolarova K, Capretti G, Milanetto AC, Ginocchi L, Lovecek M, Puzzono M, van Laarhoven HWM, Carrara S, Ivanauskas A, Papiris K, Basso D, Arcidiacono PG, Izbeki F, Chammas R, Vodicka P, Hackert T, Pasquali C, Piredda ML, Costello-Goldring E, Cavestro GM, Szentesi A, Tavano F, Wlodarczyk B, Brenner H, Kreivenaite E, Gao X, Bunduc S, Vermeulen RCH, Schneider MA, Latiano A, Gioffreda D, Testoni SGG, Kupcinskas J, Lawlor RT, Capurso G, Malats N, Campa D, and Canzian F (2021). Association of Genetic Variants Affecting microRNAs and Pancreatic Cancer Risk. Front Genet 12, 693933.

Krieger TG, Le Blanc S, Jabs J, Ten FW, Ishaque N, Jechow K, Debnath O, Leonhardt CS, Giri A, Eils R, Strobel O, and Conrad C (2021). Single-cell analysis of patient-derived PDAC organoids reveals cell state heterogeneity and a conserved developmental hierarchy. Nat Commun 12, 5826.

Klaiber U, Schnaidt ES, Hinz U, Gaida MM, Heger U, Hank T, Strobel O, Neoptolemos JP, Mihaljevic AL, Buchler MW, and Hackert T (2021). Prognostic Factors of Survival After Neoadjuvant Treatment and Resection for Initially Unresectable Pancreatic Cancer. Ann Surg 273, 154-162.

Holowatyj AN, Gigic B, Warby CA, Ose J, Lin T, Schrotz-King P, Ulrich CM, and Bernard JJ (2021). The Use of Human Serum Samples to Study Malignant Transformation: A Pilot Study. Cells 10.

Espinet E, Gu Z, Imbusch CD, Giese NA, Buscher M, Safavi M, Weisenburger S, Klein C, Vogel V, Falcone M, Insua-Rodriguez J, Reitberger M, Thiel V, Kossi SO, Muckenhuber A, Sarai K, Lee AYL, Backx E, Zarei S, Gaida MM, Rodriguez-Paredes M, Donato E, Yen HY, Eils R, Schlesner M, Pfarr N, Hackert T, Plass C, Brors B, Steiger K, Weichenhan D, Arda HE, Rooman I, Kopp JL, Strobel O, Weichert W, Sprick MR, and Trumpp A (2021). Aggressive PDACs Show Hypomethylation of Repetitive Elements and the Execution of an Intrinsic IFN Program Linked to a Ductal Cell of Origin. Cancer Discov 11, 638-659.

Dudek M, Pfister D, Donakonda S, Filpe P, Schneider A, Laschinger M, Hartmann D, Huser N, Meiser P, Bayerl F, Inverso D, Wigger J, Sebode M, Ollinger R, Rad R, Hegenbarth S, Anton M, Guillot A, Bowman A, Heide D, Muller F, Ramadori P, Leone V, Garcia-Caceres C, Gruber T, Seifert G, Kabat AM, Mallm JP, Reider S, Effenberger M, Roth S, Billeter AT, Muller-Stich B, Pearce EJ, Koch-Nolte F, Kaser R, Tilg H, Thimme R, Boettler T, Tacke F, Dufour JF, Haller D, Murray PJ, Heeren R, Zehn D, Bottcher JP, Heikenwalder M, and Knolle PA (2021). Auto-aggressive CXCR6(+) CD8 T cells cause liver immune pathology in NASH. Nature 592, 444-449.

Deczkowska A, David E, Ramadori P, Pfister D, Safran M, Li B, Giladi A, Jaitin DA, Barboy O, Cohen M, Yofe I, Gur C, Shlomi-Loubaton S, Henri S, Suhail Y, Qiu M, Kam S, Hermon H, Lahat E, Ben Yakov G, Cohen-Ezra O, Davidov Y, Likhter M, Goitein D, Roth S, Weber A, Malissen B, Weiner A, Ben-Ari Z, Heikenwalder M, Elinav E, and Amit I (2021). XCR1(+) type 1 conventional dendritic cells drive liver pathology in non-alcoholic steatohepatitis. Nat Med 27, 1043-1054.

Al-Shaheri FN, Alhamdani MSS, Bauer AS, Giese N, Buchler MW, Hackert T, and Hoheisel JD (2021). Blood biomarkers for differential diagnosis and early detection of pancreatic cancer. Cancer Treat Rev 96, 102193.

Al-Shaheri FN, Alhamdani MSS, Bauer AS, Giese N, Buchler MW, Hackert T, and Hoheisel JD (2021). Blood biomarkers for differential diagnosis and early detection of pancreatic cancer. Cancer Treat Rev 96, 102193.

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