Kliniken & Institute … Kliniken Zentrum für Innere… Innere Medizin VIII:… Jobs

Postdoc position in the Backs lab

We are currently looking for a highly motivated postdoc to join our international research team. Project title: Metabolo-epigenetic control of myocardial calcium handling.

Please send your application to: Sekretariat.Backs(at)med.uni-heidelberg.de

 

PhD position in the Backs lab

Metabo-epigenetic regulatory circuits of heart disease caused by inherited and acquired lipid accumulation

Inherited neutral lipid storage disease with cardiomyopathy (NLSD-CM) is caused by mutations in PNPLA2, encoding a lipid droplet (LD)-associated protein, and is characterized by massive lipid accumulation. Using mouse models of genetic and acquired NLSD-CM, we have demonstrated the involvement of histone deacetylases (HDACs) in the development of diastolic dysfunction. The aim of the project is to elucidate the molecular mechanisms by which HDACs regulate lipid metabolism and cardiac function, to unravel the metabo-epigenetic circuits connecting chromatin state with metabolic and lysosomal-autophagic control in NLSD-CM.

If you have a background (master or equivalent) in molecular biology, biochemistry, medicine or related and you are keen to investigate fundamental molecular circuits causing cardiomyopathy, this may be the right position for you. 

Please send your application to Sekretariat.Backs(at)med.uni-heidelberg.de

PhD position in the van den Hoogenhof lab

We currently have a PhD-position available to work on splicing mechanisms in the heart. Are you interested in molecular biology and have a knack for bio-informatics? Please apply with your CV and motivation at maarten.vandenhoogenhof(at)med.uni-heidelberg.de!

Postdoc and PhD positions in the Gilsbach lab

The lab of Ralf Gilsbach is currently looking for PhD students (https://tinyurl.com/A02-CRC1550-RG) and a postdoc to join our research team embedded into the CRC1550 „Molecular Circuits of Heart Disease“ and the CRC1425 „ScarCare“.

Please send your application to: ralf.gilsbach(at)uni-heidelberg.de

Open positions in the CRC1550

A01: Metabo-epigenetic regulatory circuits of heart disease caused by inherited and acquired lipid accumulation: 1 PhD student at the lab of Johannes Backs (Heidelberg University), https://www.klinikum.uni-heidelberg.de/zentrum-fuer-innere-medizin-medizin-klinik/innere-medizin-viii-institut-fuer-experimentelle-kardiologie/)

www.klinikum.uni-heidelberg.de/zentrum-fuer-innere-medizin-medizin-klinik/innere-medizin-viii-institut-fuer-experimentelle-kardiologie/jobs

A01: Metabo-epigenetic regulatory circuits of heart disease caused by inherited and acquired lipid accumulation: 1 Postdoc position at the lab of Almut Schulze (DKFZ,

www.dkfz.de/de/tumor-metabolismus-microenvironment/index.php)

A02: Function and modulation of genomic cardiomyopathy enhancers: 2 PhD students at the lab of Ralf Gilsbach (Heidelberg University

https://tinyurl.com/Gilsbach-cardioscience)

tinyurl.com/A02-CRC1550-RG

A03: Interplay between epigenetics and metabolism in cardiac laminopathies 2 PhD students at the lab of Gergana Dobreva (Heidelberg University)

https://www.umm.uni-heidelberg.de/experimentelle-kardiologie/

A05: Role of the splice target CAMK2D in RBM20 cardiomyopathy: 1 PhD student at the lab of Maarten van den Hoogenhof (Heidelberg University)

https://www.klinikum.uni-heidelberg.de/zentrum-fuer-innere-medizin-medizin-klinik/innere-medizin-viii-institut-fuer-experimentelle-kardiologie/jobs

A06: Decoding the regulatory network of RBM20: 1 Postdoc at the lab of Lars Steinmetz (EMBL, www.embl.org/groups/steinmetz/)

A07: STAR family function and interaction with RBM20 for intervening alternative splicing: 1 Postdoc at the lab of Benjamin Meder (Heidelberg University)

https://heibox.uni-heidelberg.de/f/78bf821c0cea4eb687c8/?dl=1

A08: Dysregulation of mRNA decay in MYBPC3 hypertrophic cardiomyopathy: 1 PhD student at the lab of Timon Seeger (Heidelberg University)

heibox.uni-heidelberg.de/f/519f3ff349e24d7b98a5/

B02: The role of unconventional RNA-Binding proteins in the failing heart: 1 PhD student at the lab of Matthias Hentze (EMBL)

B02: The role of unconventional RNA-Binding proteins in the failing heart: 1 PhD student at the lab of Mirko Völkers (Heidelberg University)

https://www.klinikum.uni-heidelberg.de/zentrum-fuer-innere-medizin-medizin-klinik/innere-medizin-iii-kardiologie-angiologie-und-pneumologie/forschung/forschung/grundlagenforschung/molecular-biology-of-cell-growth/summary#c145575

B04: The role of the AP-1 transcriptional complex during cardiac remodeling: 1 PhD student at the lab of Arica Beisaw (Heidelberg University)

https://heibox.uni-heidelberg.de/f/5804e99c6a564c3fb883/?dl=1

B06: Cardiocrine signaling as a regulator of cardiac homeostasis and fibrosis: 1 PhD student at the lab of Florian Leuschner (Heidelberg University)

B07: Control of cardiac homeostasis and cardiocrine signaling by protein arginine methyltransferases: 1 PhD student at the lab of Christoph Dieterich (Heidelberg University)

B09: Unraveling molecular circuits leading to catecholamine-driven ventricular arrhythmias: 1 Postdoc at the lab of Marc Freichel (Heidelberg University)

karriere.klinikum.uni-heidelberg.de/index.php

B09: Unraveling molecular circuits leading to catecholamine-driven ventricular arrhythmias: 1 PhD student at the lab of Marc Freichel (Heidelberg University)

https://karriere.klinikum.uni-heidelberg.de/index.php?ac=jobad&id=15286

B09: Unraveling molecular circuits leading to catecholamine-driven ventricular arrhythmias: 1 PhD student at the lab of Rebecca Levinson (Heidelberg University, www.klinikum.uni-heidelberg.de/personen/phd-rebecca-levinson-7089)

B10: Deciphering molecular circuits of cardiac remodeling and dysfunction via an integrative reverse approach: 1 PhD student at the lab of Norbert Frey (Heidelberg University)

B10: Deciphering molecular circuits of cardiac remodeling and dysfunction via an integrative reverse approach: 1 Postdoc at the group of Julio Saez Rodriguez (Heidelberg University)

https://jobrxiv.org/job/heidelberg-university-27778-postdoctoral-position-to-integrate-single-cel-multi-omics-in-heart-disease-saezlab-heidelberg/

S02: Disease modeling: 1 Postdoc position for stem cell-based and in vivo cardiac disease modeling (project leaders Timon Seeger and Matthias Dewenter; Heidelberg University)

https://heibox.uni-heidelberg.de/f/9417b3d5fd6a405da652/

INF: Infrastructure for Biobanking, Data Management and Bioinformatics: 1 Postdoc position at the group of Julio Saez-Rodriguez (Heidelberg University)

https://jobrxiv.org/job/heidelberg-university-27778-staff-bioinformatician-position-omics-in-heart-disease-saezlab-heidelberg/

INF: Infrastructure for Biobanking, Data Management and Bioinformatics: 1 Postdoc position at the lab of Christoph Dieterich (Heidelberg University)

INF: Infrastructure for Biobanking, Data Management and Bioinformatics: 1 Postdoc position at the CardioBiobank (Tanja Weis, Heidelberg University)

https://karriere.klinikum.uni-heidelberg.de/index.php?ac=jobad&id=15496

Job description:

The job description depends on the position you are interested in. Please refer to the respective job ad above or contact the respective group leader.

Requirements:

We are seeking for highly motivated, skilled and career-minded PhD students and postdocs who are keen to investigate the molecular origins of acquired and genetic heart diseases. Successful candidates as PhD students must hold a university degree (master) or equivalent and should have a pronounced interest in cardio science. We seek candidates with a highly collaborative spirit and enthusiasm to unmask yet hidden disease mechanisms. Further details are provided in the individual job ads above or can be asked from the respective group leader.

We offer:

  • International, attractive and highly collaborative working environment
  • Interdisciplinary research approach across experimental, clinical and computational cardiology
  • Unique biomedical research ecosystem
  • Dedicated qualification program by Integrated Research Training Group for CardioScience
  • For PhD students: Enrollment in roof graduate schools: Heidelberg Biosciences international Graduate School (HBIGS) for positions at University Hospital Heidelberg; EMBL International PhD program (EIPP) for positions at EMBL and DKFZ International PhD program for positions at DKFZ

Important notice:

The University Hospital and the DKFZ are subject to the regulations of the Infection Protection Act (IfSG). As a consequence, only persons who present proof of immunity against measles as well as against COVID-19 may work at the University Hospitals and at DKFZ.

Earliest Possible Start Date:

01.07.2022

Duration:

The position is limited to 3 years with the possibility of prolongation.

Application Deadline:

 

Contact:

Please refer to the respective job ad above or contact the respective group leader.

 

The CRC 1550 is committed to increase the proportion of women in all areas and positions in which women are underrepresented. Qualified female applicants are therefore particularly encouraged to apply.

Among candidates of equal aptitude and qualifications, a person with disabilities will be given preference.

To apply for a position, please refer to the job ads mentioned above