Cardiovascular disease accounts for a large proportion of morbidity and mortality worldwide, and there remains a pressing need to promote cardiac repair following myocardial injury.  The Mechanisms of Cardiac Regeneration and Repair Lab uses a combination of in vivo, in vitro, and -OMICS approaches to understand molecular mechanisms of cardiomyocyte regeneration in zebrafish, a lower vertebrate species that is capable of regenerating lost cardiac cell types following injury.  We are specifically interested in transcriptional and epigenetic networks involved in the regeneration process, and how intercellular communication contributes to cardiomyocyte replenishment.  Ultimately, our goal is to use this knowledge to develop therapeutic strategies to promote cardiac repair in the adult mammalian heart.