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Publikationen 2019

Braun MS, Wang E, Zimmermann S, Boutin S, Wagner H, Wink M. 2019
Kocuria tytonis sp. nov., isolated from the uropygial gland of an American barn owl (Tyto furcata).
Int J Syst Evol Microbiol. 2019 Feb;69(2):447-451. doi: 10.1099/ijsem.0.003170.

Braun MS, Wang E, Zimmermann S, Boutin S, Wagner H, Wink M. 2019
Kocuria tytonicola, new bacteria from the preen glands of American barn owls (Tyto furcata)
Systematic and Applied Microbiology 2019;42,2:198-204. doi: 10.1016/j.syapm.2018.11.004

Buchholz U, Dullin J, Lück C, Petzold A, Petzold M, Berges M, Exner M, Jahn HJ, Lachmann R, Brodhun B, Lelgemann M. 2019
Ausbruch ambulant erworbener Legionellosen in Bremen 2015 und 2016 – Erfahrungen, Ergebnisse, Entscheidungen.
Epid Bull 2019;28:251-257. doi: 10.25646/6199

Burckhardt I. 2019
Laborautomation in der Mikrobiologie - Zu einer schnelleren und besseren individualisierten Diagnostik
Biospektrum (2019) 25: 620. doi: 10.1007/s12268-019-0204-1

Burckhardt I, Last K, Zimmermann S. 2019.
Shorter Incubation Times for Detecting Multi-drug Resistant Bacteria in Patient Samples: Defining Early Imaging Time Points Using Growth Kinetics and Total Laboratory Automation
Ann Lab Med 2019;39:43-49. doi: 10.3343/alm.2019.39.1.43

Chakraborty S, Kubatzky KF, Mitra DK. 2019
An Update on Interleukin-9: From Its Cellular Source and Signal Transduction to Its Role in Immunopathogenesis
Int. J. Mol. Sci. 2019, 20, 2113. doi: 10.3390/ijms20092113

Hildebrand D, Decker SO, Koch C, Schmitt FCF, Ruhrmann S, Schneck E, Sander M, Weigand MA, Brenner T, Heeg K, Uhle F. 2019
Host-Derived Delta-Like Canonical Notch Ligand 1 as a Novel Diagnostic Biomarker for Bacterial Sepsis—Results From a Combinational Secondary Analysis
Front. Cell. Infect. Microbiol. 9:267 doi: 10.3389/fcimb.2019.00267

Freund I, Buhl DK, Boutin S, Kotter A, Pichot F, Marchand V, Vierbuchen T, Heine H, Motorin Y, Helm M, Dalpke AH, Eigenbrod T. 2019
2′-O-methylation within prokaryotic and eukaryotic tRNA inhibits innate immune activation by endosomal Toll-like receptors but does not affect recognition of whole organisms
RNA 2019. 25: 869-880 doi: 10.1261/rna.070243.118

Freund I, Eigenbrod T, Helm M, Dalpke AH. 2019
RNA Modifications Modulate Activation of Innate Toll-Like Receptors
Genes 2019, 10, 92. doi: 10.3390/genes10020092

Hafner A, Kolbe U, Freund I, Castiglia V, Kovarik P, Poth T, Herster F, Weigand MA, Weber ANR, Dalpke AH, Eigenbrod T. 2019
Crucial Role of Nucleic Acid Sensing via Endosomal Toll-Like Receptors for the Defense of Streptococcus pyogenes in vitro and in vivo
Front. Immunol. 10:198. doi: 10.3389/fimmu.2019.00198

Hildebrand D, Metz-Zumaran C, Jaschkowitz G, Heeg K. 2019
Silencing SOCS1 via Liposome-Packed siRNA Sustains TLR4-Ligand Adjuvant
Front. Immunol. 10:1279. doi: 10.3389/fimmu.2019.01279

Klein S, Menz MD, Zanger P, Heeg K, Nurjadi D. 2019
Increase in the prevalence of Panton–Valentine leukocidin and clonal shift in community-onset methicillin-resistant Staphylococcus aureus causing skin and soft-tissue infections in the Rhine-Neckar Region, Germany, 2012–2016
International Journal of Antimicrobial Agents 53 (2019) 261–267. doi: 10.1016/j.ijantimicag.2018.10.026

Nair A, Chauhan P, Saha B, Kubatzky KF. 2019
Conceptual Evolution of Cell Signaling
Int. J. Mol. Sci. 2019, 20(13), 3292. doi: 10.3390/ijms20133292

Nurjadi D, Fleck R, Lindner A, Schäfer J, Gertler M, Mueller A, Lagler H, Van Genderen PJJ, Caumes E, Kuenzli E, Gascon J, Kantele A, Grobusch MP, Heeg K, Zanger P. 2019
Import of community-associated, methicillin-resistant Staphylococcus aureus to Europe through skin and soft-tissue infection in intercontinental travellers, 2011–2016
Clinical Microbiology and Infection, Volume 25, Issue 6, 2019. doi: 10.1016/j.cmi.2018.09.023

Schmitt FCF, Brenner T, Uhle F, Loesch F, Hackert T, Ulrich A, Hofer S, Dalpke AH, Weigand MA, Boutin S. 2019
Gut microbiome patterns correlate with higher postoperative complication rates after pancreatic surgery
BMC Microbiology 201919:42 doi: 10.1186/s12866-019-1399-5

Schoilew K, Ueffing H, Dalpke A, Wolff B, Frese C, Wolff D, Boutin S. 2019
Bacterial biofilm composition in healthy subjects with and without caries experience
Journal of Oral Microbiology, 11:1, 1633194. doi: 10.1080/20002297.2019.1633194

Schirmer B, Giehl K, Kubatzky KF. 2019
Report of the Signal Transduction Society Meeting 2018—Signaling: From Past to Future
Int. J. Mol. Sci. 2019, 20(1), 227. doi: 10.3390/ijms20010227

Seebach E, Kubatzky KF. 2019
Chronic Implant-Related Bone Infections—Can Immune Modulation be a Therapeutic Strategy?
Front. Immunol. 10:1724. doi: 10.3389/fimmu.2019.01724

Wunderlich M, Block I, Landesberger Tv, Petzold M, Marschollek M, Scheithauer S. 2019
Visual Analysis of Probabilistic Infection Contagion in Hospitals
Vision, Modeling and Visualization. doi: 10.2312/vmv.20191328

 

Publikationen 2018

AL-Ani I, Zimmermann S, Reichling J and Wink M. 2018
Antimicrobial Activities of European Propolis Collected from Various Geographic Origins Alone and in Combination with Antibiotics.
Medicines 2018, 5, 2 doi: 10.3390/medicines5010002

 

Boutin S, Weitnauer M, Hassel S, Graeber SY, Stahl M, Dittrich SA, Mall MA and Dalpke AH. 2018
One time quantitative PCR detection of Pseudomonas aeruginosa to discriminate intermittent from chronic infection in Cystic Fibrosis.
J Cyst Fibros. 17(3): 348-355. doi: 10.1016/j.jcf.2017.12.007. [Epub ahead of print]

 

Braun SM, Sporer F, Zimmermann S, Wink M. 2018.
Birds, feather-degrading bacteria and preen glands: the antimicrobial activity of preen gland secretions from turkeys (Meleagris gallopavo) is amplified by keratinase.
FEMS Microbiology Ecology. fiy117. doi: 10.1093/femsec/fiy117

 

Braun MS, Wang E, Zimmermann S, Wink M. 2018.
Corynebacterium heidelbergense sp. nov., isolated from the preen glands of Egyptian geese (Alopochen aegyptiacus)
Systematic and Applied Microbiology. pii: S0723-2020(18)30052-3. doi: 10.1016/j.syapm.2018.06.002 epub 8. Juni 2018

 

Burckhardt I, Horner S, Burckhardt F, Zimmermann S. 2018.
Detection of MRSA in nasal swabs-marked reduction of time to report for negative reports by substituting classical manual workflow with total lab automation.
Eur J Clin Microbiol Infect Dis. 2018 Jun 25. doi: 10.1007/s10096-018-3308-5. [Epub ahead of print]

 

Chakraborty S, Kloos B, Roetz N, Schmidt S, Eigenbrod T, Kamitani S, Kubatzky KF. 2018.
Influence of Pasteurella multocida Toxin on the differentiation of dendritic cells into osteoclasts
Immunobiology. 223(2018) 142-150. doi: 10.1016/j.imbio.2017.09.001

 

Domhan C, Uhl P, Meinhardt A, Zimmermann S, Kleist C, Lindner T, Leotta K, Mier W, Wink M. 2018.
A novel tool against multiresistant bacterial pathogens - lipopeptide modification of the natural antimicrobial peptide ranalexin for enhanced antimicrobial activity and improved pharmacokinetics.
Int J Antimicrob Agents. 2018 Apr 9. pii: S0924-8579(18)30101-8. doi: S0924-8579(18)30101-8.

 

Domhan C, Wink M, Zimmermann, S. 2018.
Dangerously resistant [Gefährlich resistent]
DAZ Vol. 158 (22): 32-39.

 

Domhan C, Wink M, Zimmermann, S. 2018.
Overcome antimicrobial resistance [Resistenzen überwinden]
DAZ Vol. 158 (22): 40-43.

 

Grünvogel O, Colasanti O, Lee JY, Klöss V, Belouzard S, Reustle A, Esser-Nobis K, Hesebeck-Brinckmann J, Mutz P, Hoffmann K, Mehrabi A, Koschny R, Vondran FWR, Gotthardt D, Schnitzler P, Neumann-Haefelin C, Thimme R, Binder M, Bartenschlager R, Dubuisson J, Dalpke AH, Lohmann V. 2018
Secretion of Hepatitis C Virus Replication Intermediates Reduces Activation of Toll Like Receptor 3 in Hepatocytes.
Gastroenterologydoi: 10.1053/j.gastro.2018.03.020. [Epub ahead of print] IF 18,392

 

Héry-Arnaud G, Boutin S, Cuthbertson L, Elborn SJ, Tunney MM. 2018
The lung and gut microbiome: what has to be taken into consideration for cystic fibrosis?
Journal of Cystic Fibrosis Article in press. doi: 10.1016/j.jcf.2018.11.003

 

Hildebrand D, Eberle ME, Wölfle SM, Egler F, Sahin D, Sähr A, Bode K, Heeg K. 2018.
Hsa-miR-99b/let-7e/miR-125a Cluster Regulates Pathogen Recognition Receptor-Stimulated Suppressive Antigen-Presenting Cells
Front. Immunol. 9:1224. doi: 10.3389/fimmu.2018.01224

 

Hildebrand D, Uhle F, Sahin D, Krauser U, Weigand MA, Heeg K. 2018.
The Interplay of Notch Signaling and STAT3 in TLR-Activated Human Primary Monocytes.
Front. Cell. Infect. Microbiol. 8:241. doi: 10.3389/fcimb.2018.00241

 

Jakobs M, Klein S, Eigenbrod T, Unterberg AW, Sakowitz OW. 2018.
The SiLuDrain Trial: a prospective randomized controlled trial comparing standard versus silver-impregnated lumbar drains.
J Neurosurg. 2018 Jun 15:1-8 doi: 10.3171/2018.1.JNS181522 [Epub ahead of print]

 

Keller P, Freund I, Marchand V, Bec G, Huan R, Motorin Y, Eigenbrod T, Dalpke A, Heim M. 2018.
Double methylation of tRNA-U54 to 2'-O-methylthymidine (Tm) synergistically decreases immune response by Toll-like receptor 7
Nucleic Acids Res, 2018 Aug 8. doi: 10.1093/nar/gky644

 

Klein S, Klotz M, Eigenbrod T. 2018.
First isolation of Mycoplasma canis from human tissue samples following a dog bite.
New Microbes and New Infections 2018. 25:14-15 doi: 10.1016/j.nmni.2018.05.003.

 

Klein S, Nurjadi D, Horner S, Heeg K, Zimmermann S, Burckhardt I. 2018
Significant increase in cultivation of Gardnerella vaginalis, Alloscardovia omnicolens, Actinotignum schaalii, and Actinomyces spp. in urine samples with total laboratory automation.
Eur J Clin Microbiol Infect Dis. 2018 Apr 13. doi: 10.1007/s10096-018-3250-6

 

Kubatzky KF, Uhle F, Eigenbrod T. 2018.
From macrophage to osteoclast – How metabolism determines function and activity
Cytokine (2018). doi: 10.1016/j.cyto.2018.06.013

 

Nurjadi D, Heeg K, Weber ANR, Zanger P. 2018.
Toll-like receptor 9 (TLR-9) promotor polymorphisms and gene expression are associated with persistent Staphylococcus aureus nasal carriage
Clin Microbiol Infect. 2018. doi: 10.1016/j.cmi.2018.02.014

 

Nurjadi D, Boutin S, Dalpke A, Heeg K, Zanger P. 2018.
Draft Genome Sequence of Staphylococcus aureus Strain HD1410, Isolated from a Persistent Nasal Carrier
Genome Announc. 10;6(19). pii: e00411-18. doi: 10.1128/genomeA.00411-18.

 

Richter DC, Heininger A, Brenner T, Hochreiter M, Bernhard M, Briegel J, Dubler S, Grabein B, Hecker A, Kruger WA, Mayer K, Pletz MW, Storzinger D, Pinder N, Hoppe-Tichy T, Weiterer S, Zimmermann S, Brinkmann A, Weigand MA, Lichtenstern C. 2018
Bacterial sepsis : Diagnostics and calculated antibiotic therapy.
Anaesthesist. 2018 Jan 30. doi: 10.1007/s00101-017-0396-z [Epub ahead of print]

 

Rollenske T, Szijarto V, Lukasiewicz J, Guachalla LM, Stojkovic K, Hartl K, Stulik L, Kocher S, Lasitschka F, Al-Saeedi M, Schröder-Braunstein J, von Frankenberg M, Gaebelein G, Hoffmann P, Klein S, Heeg K, Nagy E, Nagy G, Wardemann H. 2017.
Cross-specificity of protective human antibodies against Klebsiella pneumoniae LPS O-antigen.
Nature Immunology 2018. doi: 10.1038/s41590-018-0106-2

 

Schirmer B, Giehl K, Kubatzky KF. 2018
Report of the Signal Transduction Society Meeting 2017-Metabolism in Health and Disease.
Int J Mol Sci. 2018 Feb 12;19(2). pii: E549. doi: 10.3390/ijms19020549.

 

Strebovsky J, Zimmer J and Dalpke AH. 2018
SOCS
Encyclopedia of Signaling Molecules. Choi, Sangdun (Ed.), Springer, New York, 2nd Edition, 5061-5068 (2018), ISBN 978-3-319-67198-7, ISBN 978-3-319-67199-4 (eBook), doi: 10.1007/978-3-319-67199-4

Publikationen 2017

Boutin S, Dalpke A. 2017
Acquisition and adaptation of the airway microbiota in the early life of cystic fibrosis patients
Molecular and Cellular Pediatrics (2017) 4:1. DOI 10.1186/s40348-016-0067-1

 

Boutin S, Depner M, Stahl M, Graeber SY, Dittrich SA, Legatzki A, von Mutius E, Mall M, Dalpke AH. 2017
Comparison of Oropharyngeal Microbiota from Children with Asthma and Cystic Fibrosis.
Mediat Inflamm. 2017;2017:5047403. doi: 10.1155/2017/5047403. Epub 2017 Dec 27.

 

Boutin S, Graeber SY, Stahl M, Dittrich SA, Mall MA, Dalpke AH.2017
Chronic but not intermittent infection with Pseudomonas aeruginosa is associated with global changes of the lung microbiome in cystic fibrosis.
Eur Respir J 50 (4): 1701086. doi: 10.1183/13993003.01086-2017 in press.

 

Boutin S, Hagenfeld D, Zimmermann H, El Sayed N, Höpker T, Greiser HK, Becher H, Kim TS, Dalpke AH. 2017
Clustering of subgingival microbiota reveals microbial disease ecotypes associated with clinical stages of periodontitis in a cross-sectional study.
Front Microbiol. 8:340. doi: 10.3389/fmicb.2017.00340

 

Braun MS, Wang E, Zimmermann S, Boutin S, Wink M. 2017
Kocuria uropygioeca sp. nov. and Kocuria uropygialis sp. nov., isolated from the preen glands of Great Spotted Woodpeckers (Dendrocopos major).
Syst Appl Microbiol. 2017 Nov 15. pii: S0723-2020(17)30136-4. doi: 10.1016/j.syapm.2017.09.005. [Epub ahead of print]

 

Burckhardt I, Panitz J, Burckhardt F, Zimmermann S. 2017
Identification of Streptococcus pneumoniae: Development of a Standardized Protocol for Optochin Susceptibility Testing Using Total Lab Automation
BioMed Research International; Volume 2017 (2017), Article ID 4174168, 7 pages. doi: 10.1155/2017/4174168

 

Chakraborty S, Kloos B, Harre U, Schett G, Kubatzky KF. 2017
Pasteurella multocida Toxin Triggers RANKL-Independent osteoclastogenesis
Front. Immunol. doi: 10.3389/fimmu.2017.00185

 

Chakraborty S, Kloos B, Roetz N, Schmidt S, Eigenbrod T, Kamitani S, Kubatzky KF. 2017
Influence of Pasteurella multocida Toxin on the differentiation of dendritic cells into osteoclasts.
Immunobiology. 2018 Jan;223(1):142-150. doi: 10.1016/j.imbio.2017.09.001. Epub 2017 Sep 12.

 

Decker SO, Sigl A, Grumaz C, Stevens P, Vainshtein Y, Zimmermann S, Weigand MA, Hofer S, Sohn K, Brenner T. 2018
Immune-Response Patterns and Next Generation Sequencing Diagnostics for the Detection of Mycoses in Patients with Septic Shock—Results of a Combined Clinical and Experimental Investigation
Int. J. Mol. Sci. 2017, 18, 1796. doi: 10.3390/ijms18081796.

 

Giesbrecht K, Eberle ME, Wölfle SJ, Sahin D, Sähr A, Oberhardt V, Menne Z, Bode KA, Heeg K, Hildebrand D. 2017
IL-1β As Mediator of Resolution That Reprograms Human Peripheral Monocytes toward a Suppressive Phenotype.
Front Immunol. Aug 3;8:899. doi: 10.3389/fimmu.2017.00899. eCollection 2017.Front Immunol.

 

Günther F, Blessing B, Tacconelli E, Mutters NT. 2017
MRSA decolonization failure-are biofilms the missing link?
Antimicrob Resist Infect Control. 2017 Mar 28; 6:32. doi: 10.1186/s13756-017-0192-1

 

Hagenfeld D, Mutters NT, Harks I, Koch R, Kim TS, Prehm P. 2017
Hyaluronan-mediated mononuclear leukocyte binding to gingival fibroblasts.
Clin Oral Investig. 2017 Aug 12. doi: 10.1007/s00784-017-2188-x.

 

Hellmuth I, Freund I, Schlöder J, Seidu-Larry S, Thüring K, Slama K, Langhanki J, Kaloyanova S, Eigenbrod T, Krumb M, Röhm S, Peneva K, Opatz T, Jonuleit H, Dalpke AH, Helm M. 2017
Bioconjugation of small molecules to RNA impedes its recognition by Toll-like receptor 7 (TLR7).
Front. Immunol. 8:312. doi: 10.3389/fimmu.2017.00312

 

Ibert, F., Eckstein, M., Günther, F., Mutters, N.T.
The relationship between subjective perception and the psychological effects of patients in spatial Isolation. 2017
GMS Hyg Infect Control. 2017;12:Doc11

 

Kamradt T, Klein S, Zimmermann S, Schröder-Braunstein J, Fürstenberg CH, Hensel C, Weidner N, Hug A. 2017
Bacterial Load of Conditioned Pressure Ulcers is not a Predictor for Early Flap Failure in Spinal Cord Injury.
Spinal Cord advance online publication. January 10, 2017; doi:10.1038/sc.2016.186 (epub January 10, 2017)

 

Kaiser S J, Mutters N T, Blessing B, Günther F. 2017.
Natural isothiocyanates express antimicrobial activity against developing and mature biofilms of Pseudomonas aeruginosa.
Fitoterapia. 2017 Apr 5; doi: 10.1016/j.fitote.2017.04.006

 

Klöss V, Grünvogel O, Wabnitz G, Eigenbrod T, Ehrhardt S, Lasitschka F, Lohmann V and Dalpke AH. 2017
Interaction and Mutual Activation of Different Innate Immune Cells Is Necessary to Kill and Clear Hepatitis C Virus-Infected Cells.
Front. Immunol. 8:1238 doi: 10.3389/fimmu.2017.01238

 

Kuon RJ, Togawa R, Vomstein K, Weber M, Goeggl T, Strowitzki T, Markert UR, Zimmermann S, Daniel V, Dalpke AH, Toth B. 2017
Higher prevalence of colonization with Gardnerella vaginalis and gram-negative anaerobes in patients with recurrent miscarriage and elevated peripheral natural killer cells.
J Reprod Immunol. 120:15-19. doi: 10.1016/j.jri.2017.03.001.

 

Marchand V, Pichot F, Thüring K, Ayadi L, Freund I, Dalpke A, Helm M, Motorin Y. 2017
Next-Generation Sequencing-Based RiboMethSeq Protocol for Analysis of tRNA 2'-O-Methylation.
Biomolecules. 2017 Feb 9;7(1). pii: E13. doi: 10.3390/biom7010013.

 

Mijosek T, Jelic M, Mijosek V, Maguire I. 2017
Molecular and morphometric characterisation of the invasive signalcrayfish populations in Croatia
Limnologica 63 (2017) 107–118. doi: 10.1016/j.limno.2017.02.003

 

Mracsko E, Stegemann-Koniszewski S, Na SY, Dalpke A, Bruder D, Lasitschka F, Veltkamp R. 2017
A Mouse Model of Post-Stroke Pneumonia Induced by Intra-Tracheal Inoculation with Streptococcus pneumoniae.
Cerebrovasc Dis. 2017 Jan 4;43(3-4):99-109. doi: 10.1159/000452136.

 

Mutters NT, De Angelis G, Restuccia G, Di Muzio F, Schouten J, Hulscher M, Antonelli M, Tacconelli E. 2017
Use of evidence-based recommendations in an antibiotic care bundle for the intensive care unit.
Int J Antimicrob Agents. 2017 Jul 10. doi: 10.1016/j.ijantimicag.2017.06.020

 

Mutters NT, Friedrich AW. 2017
Infectiepreventieopleiding: metacompetentie en Europese competentie.
Ned Tijdschr Med Microbiol 2017;25:nr3

 

Mutters NT, Heeg K, Späth I, Henny N, Günther F. 2017
Improvement of infection control management by routine molecular evaluation of pathogen clusters.
Diagn Microbiol Infect Dis. 2017 Jan 25 doi: 10.1016/j.diagmicrobio.2017.01.013

 

Mutters NT, Malek V, Agnandji ST, Günther F, Tacconelli E. 2017
Evaluation of the scientific impact of the Ebola epidemic: a systematic review.
Clin Microbiol Infect. 2017 Sep 4.

 

Ng Kuet Leong N, Brombacher F, Dalpke AH and Weitnauer M. 2017
Crosstalk between glucocorticoids and IL-4 modulates Ym1 expression in alternatively activated myeloid cells.
Immunobiology, in press doi:  10.1016/j.imbio.2017.02.003

 

Nurjadi D, Heeg K, Zanger P. 2017.
A Trial of Antibiotics for Smaller Skin Abscesses.
N Engl J Med. 28;377(26):e36. doi: 10.1056/NEJMc1711124.

 

Nurjadi D, Klein S, Zimmermann S, Heeg K, Zanger P. 2017
Transmission of ST8-USA300 Latin American Variant Methicillin-Resistant Staphylococcus aureus on a Neonatal Intensive Care Unit: Recurrent Skin and Soft- Tissue Infections as a Marker for Epidemic Community-Associated-MRSA Colonization.
Infect Control Hosp Epidemiol. 2017 May 18:1-3. doi: 10.1017/ice.2017.88. [Epub ahead of print]

 

Pulcini C, Tebano G, Mutters NT, Tacconelli E, Cambau E, Kahlmeter G, Jarlier V; EUCIC-ESGAP-EUCAST Selective Reporting Working Group.2017
Selective reporting of antibiotic susceptibility test results in European countries: an ESCMID cross-sectional Survey.
Int J Antimicrob Agents. 2017

 

Richter DC, Heininger A, Brenner T, Hochreiter M, Bernhard M, Briegel J, Dubler S, Grabein B, Hecker A, Krüger WA, Mayer K, Pletz MW, Störzinger D, Pinder N, Hoppe-Tichy T, Weiterer S, Zimmermann S, Brinkmann A, Weigand MA, Lichtenstern C. 2017
Bacterial sepsis : Diagnostics and calculated antibiotic therapy.
Anaesthesist. 2017 Oct;66(10):737-761. doi: 10.1007/s00101-017-0363-8.

 

Schmitt FCF, Freund I, Weigand MA; Helm M, Dalpke AH, Eigenbrod E. 2017
Identification of an optimized 2′-O-methylated trinucleotide RNA motif inhibiting Toll-like receptors 7 and 8
RNA.23(9):1344-1355. doi:10.1261/rna.061952.117

 

Tschudin-Sutter S, Lucet JC, Mutters NT, Tacconelli E, Zahar JR, Harbarth S. 2017
Contact precautions for preventing nosocomial transmission of ESBL-producing Escherichia coli - a point/counterpoint review.
Clin Infect Dis. 2017 Apr 3. doi: 10.1093/cid/cix258.

 

Zimmermann S, Burckhardt I. 2017
Development and Application of MALDI-TOF for Detection of Resistance Mechanisms
Eds. Shah H, Ghabria S.
MALDI-TOF and TANDEM MS for Clinical Microbiology, John Wiley & Sons Ltd., 2017, 1st Edition.

Publikationen 2016

Braun MS, Zimmermann S, Danner M, Rashid H, Wink M. 2016
Corynebacterium uropygiale sp. nov., isolated from the preen gland of Turkeys (Meleagris gallopavo).
Syst Appl Microbiol http://dx.doi.org/10.1016/syapm.2015.12.001

 

Bender JK, Fleige C, Klare I, Fiedler S, Mischnik A, Mutters NT, Dingle KE, Werner G. 2016
Detection of a cfr(B) Variant in German Enterococcus faecium Clinical Isolates and the Impact on Linezolid Resistance in Enterococcus spp.
PLoS One November 28, 2016

 

Borde JP, Sitaru G, Kopp WH, Ruhparwar A, Ehlermann P, Lasitschka L, Dalpke A, Heininger A. 2016
Heart transplantation as salvage therapy for progressive prosthetic valve endocarditis due to methicillin-resistant Staphylococcus epidermidis (MRSE).
Journal of Cardiothoracic Surgery (2016) 11:100; doi: 10.1186/s13019-016-0505-0

 

Burckhardt I, Panitz J, van der Linden M, Zimmermann S. 2016
Streptococcus pneumoniae as an agent of urinary tract infections – a laboratory experience from 2010 to 2014 and further characterization of strains
Diagn Microbil Infect Dis; 86(2016)97-101. doi: 10.1016/j.diagmicrobio.2016.06.009

 

Dalpke A, Hofko M, Zimmermann S. 2016
Development of a real-time PCR protocol requiring minimal handling for detection of
vancomycin-resistant enterococci (VRE) with the fully automated BD MAX System
J. Clin. Microbiol.; doi: 10.1128/JCM.00768-16

 

Dalpke A, Zimmermann S, Schnitzler P. 2016
Underdiagnosing of Mycoplasma pneumoniae infections as revealed by use of a respiratory multiplex PCR panel. 
Diagn Micr Infec Dis; doi: 10.1016/j.diagmicrobio.2016.06.013 [in press]

http://audioslides.elsevier.com//ViewerLarge.aspx?source=1&doi=10.1016/j.diagmicrobio.2016.06.013

Dubler S, Zimmermann S, Fischer M, Schnitzler P, Bruckner T, Weigand MA, Frank U, Hofer S, Heininger A. 2016
Bacterial and viral contamination of breathing circuits after extended use – an aspect of patient safety?
Acta Anaesthesiologica Scandinavica; http://www.ncbi.nlm.nih.gov/pubmed/27470996

Günther F, Merle U, Frank U, Gaida MM, Mutters NT. 2016
Pseudobacteremia outbreak of biofilmforming Achromobacter xylosoxidans – environmental Transmission
BMC Infectious Diseases (2016) 16:584; doi: 10.1186/s12879-016-1909-0

Günther F, Rudolph K, Frank U, Mutters NT. 2016
Improvement of Hand Hygiene Quality andCompliance Using Bioburden Measurementand Online Feedback in Germany
Infect Control Hosp Epidemiol 2016;1–4

Günther F, Scherrer M, Kaiser SJ, DeRosa A, Mutters NT. 2016
Comparative testing of disinfectant efficacy on planktonic bacteria and bacterial biofilms using a new assay based upon kinetic analysis of metabolic activity.
J Appl Microbiol. 2016 Nov 21. doi: 10.1111/jam.13358. [Epub ahead of print]PMID: 27868317 [PubMed - as supplied by publisher]

 

Hildebrand D, Kubatzky KF. 2016
Phospho-Flow Analysis of Primary Mouse Cells After HDAC Inhibitor Treatment.
Methods Mol Biol. 2017;1510:233-243.

 

 

Kaase M, Schimanski S, Schiller R, Beyreiß B, Thürmer A, Steinmann J, Kempf VA, Hess C, Sobottka I, Fenner I, Ziesing S, Burckhardt B, von Müller L, Hamprecht A, Tammer I, Wantia N, Becker K, Holzmann T, Furitsch M, Volmer G, Gatermann SG. 2016
Multicentre investigation of carbapenemase-producing Escherichia coli and Klebsiella pneumoniae in German hospitals. 
Int J Med Microbiol.; doi: 10.1016/j.ijmm.2016.05.009 [in press]

Kaiser SJ, Mutters NT, Backhaus J, Frank U, Günther F. 2016
Sterility testing of injectable products: evaluation of the growth based BacT/ALERT® 3D™ Dual T culture system. 
PDA J Pharm Sci Technol; June 20, 2016; doi:10.5731/pdajpst.2016.006460

 

Kaiser SJ, Mutters NT, DeRosa A, Ewers C, Frank U, Günther F. 2016
Determinants for persistence of Pseudomonas aeruginosa in hospitals: interplay between resistance, virulence and biofilm formation

Eur J Clin Microbiol Infect Dis; doi: 10.1007/s10096-016-2792-8

 

Klein S, Nurjadi D, Eigenbrod T, Bode KA. 2016
Evaluation of antibiotic resistance to orally administrable antibiotics in staphylococcal bone and joint infections in one of the largest university hospitals in Germany: is there a role for fusidic acid?
Int J Antimicrob Agents http://dx.doi.org/10.1016/ijantimicag.2015.12.002

 

Mijošek V, Lasitschka F, Warth A, Zabeck H, Dalpke AH, Weitnauer M. 2016
Endoplasmic Reticulum Stress Is a Danger Signal Promoting Innate Inflammatory Responses in Bronchial Epithelial Cells.
J Innate Immun. 2016;8(5):464-78. doi: 10.1159/000447668.

 

Mutters NT, Bieber CP, Hauck C, Reiner G, Malek V, Frank U. 2016
Comparison of livestock-associated and health care–associated MRSA—genes, virulence, and resistance
Diagnostic Microbiology and Infectious Disease; xxx (2016) xxx–xxx [in press]

 

Mutters NT, Guenther F, Frank U, Mischnik A.2016
Costs and possible benefits of a two-tier infection control management strategy consisting of
active screening for multidrug-resistant organisms and tailored control measures.
Journal of Hospital Infection; xxx (2016) 1-6; http://dx.doi.org/10.1016/j.jhin.2016.02.013

 

Mutters R, Mutters NT.
Hygiene and infection control measures in intensive care units.
Med Klin Intensivmed Notfmed; 2016 May 4.

 

Noack K, Mahendrarajah N, Hennig D, Schmidt L, Grebien F, Hildebrand D, Christmann M, Kaina B, Sellmer A, Mahboobi S, Kubatzky K, Heinzel T, Krämer OH. 2016
Analysis of the interplay between all-trans retinoic acid and histone deacetylase inhibitors in leukemic cells.
Arch Toxicol.2016 Nov 2. [Epub ahead of print]

 

Nurjadi D, Kain M, Marcinek P, Gaile M, Heeg K, Zanger P. 2016
Ratio of T-Helper Type 1 (Th1) to Th17 Cytokines in Whole Blood Is Associated With Human β-Defensin 3 Expression in Skin and Persistent Staphylococcus aureus Nasal Carriage
J INFECT DIS. 2016;214:1744–51 DOI: 10.1093/infdis/jiw440

 

Rappold LC, Vogelgsang L, Klein S, Bode K, Enk AH, Haenssle HA.
Primary cutaneous diphtheria: management, diagnostic workup, and treatment as exemplified by a rare case report.
J Dtsch Dermatol Ges. 2016 Jul;14(7):734-6.

 

Sastalla I, Monack DM, Kubatzky KF. 2017
Editorial: Bacterial Exotoxins: How Bacteria Fight the Immune System.
Front Immunol. 2016 Aug 2;7:300. doi: 10.3389/fimmu.2016.00300. No abstract available.

 

Tacconelli E, Cataldo MA, Paul M, Leibovici L, Kluytmans J, Schröder W, Foschi F, De Angelis G,
De Waure C, Cadeddu C, Mutters NT, Gastmeier P, Cookson B. 2016
STROBE-AMS: recommendations to optimise reporting of epidemiological studies on antimicrobial resistance and informing improvement in antimicrobial stewardship.
BMJ Open; 6:e010134.doi:10.1136/bmjopen-2015-010134

 

Tacconelli E, Müller NF, Lemmen S, Mutters NT, Hagel S, Meyer E. 2016
Infektionsrisiko bei aseptischen operativen Eingriffen.
Dtsch Arztebl Int 2016; 113: 271–278.doi: 10.3238/arztebl.2016.0271

 

Weitnauer M, Mijosek V, Dalpke AH. 2016
Control of local immunity by airway epithelial cells.
Mucosal Immunol. 2016 Mar; 9(2):287-98. doi: 10.1038/mi.2015.126. Epub 2015 Dec 2. Review

 

Zimmer J, Weitnauer M, Boutin S, Küblbeck G, Thiele S, Walker P, Lasitschka F, Lunding L, Orinska Z, Vock C, Arnold B, Wegmann M, Dalpke A. 2016
Nuclear localization of suppressor of cytokine signaling-1 regulates local immunity in the lung fronstiers in Immunology http://dx.doi.org/10.3389/fimmu.2016.00514

Publikationen 2015

Al-Ani, I., S. Zimmermann, J. Reichling, M. Wink. 2015
Pharmacological synergism o bee venom and melittin with antibiotics and plant secondary metabolites against multi-drug resistant microbial pathogens.
Phymed 22: 245-255

 

Boutin, S., S.Y. Graeber, M. Weitnauer, J. Panitz, M.Stahl, D. Clausnitzer, L. Kaderali, G. Einarsson, M.M. Tunney, J.S. Elborn, M.A. Mall, A.H. Dalpke. 2015
Comparison of microbiomes from different niches of upper and lower airways in children and adolescents with cystic fibrosis.
PLOS One 10(1): e0116029; doi: 10.1371/journal.pone.0116029

 

Brooke, R.J., N.T. Mutters, O. Péter, M.E.E. Kretzschmar. 2015
Exposure to low doses of Coxiella burnetii caused high illness attack rates: Insights from combining human challenge and outbreak data.
Epidemics http://dx.doi.org/10.1016/j.epidem.2015.12.004

 

Dalpke, A.H., M. Hofko, F. Hamilton, L. Mackenzie, S. Zimmermann, K. Templeton. 2015
Evaluation of the BD MAXTM StaphSR assay for rapid identification of Staphylococcus aureus and methicillin-resistant S. aureus in positive blood culture broths.
J Clin Microbiol doi:10.1128/JCM.01922-15

 

Dapunt, U., O. Spranger, S. Gantz, I. Burckhardt, S. Zimmermann, G. Schmidmaier, A. Moghaddam. 2015
Are atrophic long-bone nonunions associated with low-grade infections?
Therapeutics and Clinical Risk Management 11: 1843-1852

  

Eigenbrod, T., A.H. Dalpke. 2015
Bacterial RNA: An Underestimated Stimulus for Innate Immune Responses.
J immunol doi:10.4049/jimmunol.1500530

 

Eigenbrod, T., P. Keller, S. Kaiser, K. Rimbach, A.H. Dalpke, M. Helm. 2015
Recognition of Specified RNA Modifications by the Innate Immune System.
Methods Enzymol 560: 73-89

 

Eigenbrod, T., K. Pelka, E. Latz, B. Kreikemeyer, A.H. Dalpke. 2015
TLR8 Senses Bacterial RNA in Human Monocytes and Plays a Nonredundant Role for Recognition of Streptococcus pyogenes.
J immunol doi:10.4049/jimmunol.1403173

 

F. Günther, S.J. Kaiser, T. Fries, U. Frank, N.T. Mutters. 2015
Susceptibility of multidrug resistant clinical pathogens to a chlorhexidine formulation
J PREV MED HYG 2015; 56:E1-E4

 

Gielen, V., A. Sykes, J. Zhu, B. Chan, J. Macintyre, N. Regamey, E. Kieninger, A. Gupta, A. Shoemark, C. Bossley, J. Davies, S. Saglani, P. Walker, S.E. Nicholson, A.H. Dalpke, Q.M. Kon, A. Bush, S.L. Johnston, M.R. Edwards. 2015
Increased nuclear SOCS1 in asthmatic bronchial epithelium suppresses rhinovirus induction of innate inerferons.
J Allergy Clin Immunol pii: S0091-6749(14)03667-7; doi: 10.1016/j.jaci.2014.11.039. [Epub ahead of print]

 

Dagmar Hildebrand, Klaus Heeg, Katharina F. Kubatzky. 2015
Pasteurella multocida Toxin manipulaties T Cell Differentiation
Frontiers in Micorbiology doi:10.3389/fmicb.2015.01273

 

Klare, I., C. Fleige, U. Geringer, A. Thürmer, J. Bender, N.T. Mutters, A. Mischnik, G. Werner. 2015
Increased frequency of linezolid resistance among clinical Enterococcus faecium isolates from German hospital patients.
J Glob Antimicrob Resist

 

Bianca Kloos, Sushmita Chakraborty, Sonja G. Lindner, Katrin Noack, Ulrike Harre, Georg Schett, Oliver H. Krämer, Katharina F. Kubatzky. 2015
Pasteurella multocida toxin- induced osteoclastogenesis requires mTOR activation
Cell Communication and Signaling DOI:10.1186/s12964-015-0117-7

 

Lichtenstern, C., C. Herold, M. Mieth, T. Brenner, S. Decker, C.J. Busch, S. Hofer, S. Zimmermann, M.A. Weigand, M. Bernhard. 2015
Relevance of Candida and other mycoses for morbidity and mortality in severe sepsis and septic shock due to peritonitis.
Mycosis doi:10.1111/myc.12331

 

Liesz, A., A. Dalpke, E. Mracsko, D.J. Antoine, S. Roth, W. Zhou, H. Yang, S.Y. Na, M. Akhisaroglu, T. Fleming, T. Eigenbrod, P.P. Nawroth, K.J. Tracey, R. Veltkamp. 2015
DAMP Signaling is a Key Pathway Inducing Immune Modulation after Brain Injury.
J Neurosci 35(2): 583-598

 

Mischnik,A., E. Tacconelli, N.T. Mutters. 2015
Fidaxomicin: Ein neues makrozyklisches Antibiotikum halbiert die Rückfallquote bei Darminfektionen durch Clostridium difficile. Expertenkommentar.
J Med Drug Rev 5: 49-59

 

Mischnik, A., M. Trampe, S. Zimmermann. 2015
Evaluation of the Impact of Automated Specimen Inoculation, Using Previ Isola, on the Quality of and Technical Time for Stool Cultures.
Ann Lab Med http://dx.doi.org/10.3343/alm.2015.35.1

 

Mutters, N.T., I. Burckhardt, K. Heeg. 2015
MALDI-TOF Mass Spectrometry as a Tool for Epidemiological Outbreak Analysis - Can it Work?
J Med Diagn Meth 4 (4), 184

 

Mutters, N.T., U. Frank. 2015
Prävention nosokomialer Infektionen in Risikobereichen.
J Env and Occu Health Sciences 20(2): 89-95

 

Mutters, N.T., U. Frank. 2015
Prävention nosokomialer Infektionen.
In: Handbuch der Intensivpflege, 42. Ausgabe

 

Mutters, N.T., F. Günther, S. Kaiser, T. Fries, U. Frank. 2015
Czy wasz Antyseptyk jest skuteczny przeciwko klinicznym scczepom wielolekoopornych drobnoustrojow? Preparat diglukonianu chlorheksydyny wykazuje skutecznosc nawet w nizszych stezeniach.
Zakazenia 15(6): 50-52

 

Mutters, N.T., F. Günther, A. Sander, A. Mischnik, U. Frank. 2015
Influx of multidrug-resistant organisms by country-to-country transfer of patients.
BMC Infect Dis 15(1): 466 doi:10.1186/s12879-015-1173-8

 

Mutters, N.T., A. Mischnik. 2015
Vancomycin-resistant enterococci: increased mortality with tigecycline?
Dtsch Med Wochenschr 140(11): 784

 

Mutters, N.T., T.R. Neubert, R. Nieth, R. Mutters. 2015
The role of Octenidol®, Glandomed® and chlorhexidine mouthwash in the prevention of mucositis and in the reduction of the oropharyngeal flora: a double-blind-randomized controlled trial.
GMS Hyg Infect Control 2015 Feb 13;10:Doc05. doi: 10.3205/dgkh000248. PMID: 25699228

  

Mutters, N.T., E. Tacconelli. 2015
Infection Prevention and Control in Europe - the picture in the Mosaic.
Clin Microbiol Infect 2015 Jun 19

 

Mutters, N.T., G. Werner, E. Tacconelli, A. Mischnik. 2015
Vancomycin-resistente Enterokokken: Welche Therapieoptionen gibt es?
Dtsch Med Wochenschr 140: 42-45

 

Mutters, N.T., S. Zimmermann, M. Kaase, A. Mischnik. 2015
Activity of temocillin, mecillinam, ceftazidime, and ceftazidime/avibactam against carbapenem-non-susceptible Enterobacteriaceae without carbapenemase production.
Eur J clin Microbiol Infect Dis doi:10.1007/s10096-015-2498-3

 

Nurjadi, D., B. Friedrich-Jänicke, J. Schäfer, P.J.J. Van Genderen, A. Goorhuis, A. Perignon, A. Neumayr, A. Mueller, A. Kantele, M. Schunk, J. Gascon, A. Stich, C. Hatz, E. Caumes, M.P. Grobusch, R. Fleck, F.P. Mockenhaupt, P. Zanger. 2015
Skin and soft tissue infections in intercontinental travellers and the import of multi-resistant Staphylococcus aureus to Europe.
Clin Microbial Infect 21: 567.e1-567.e10

 

Nurjadi, D., J. Schäfer, B. Friedrich-Jänicke, A. Mueller, A. Neumayr, A. Calvo-Cano, A. Goorhuis, N. Molhoek,  H. Lagler, A. Kantele, P.J.J. Van Genderen, J. Gascon, M.P. Grobusch, E. Caumes, C. Hatz, R. Fleck, F.P. Mockenhaupt, P. Zanger. 2015 Predominance of dfrG as determinant of trimethoprim resistance in imported Staphylococcus aureus Clin Microbial Infect 21: 1095.e5-1095.e9

 

Otter, J.A., N.T. Mutters, E. Tacconelli, A. Gikas, A.H. Holmes. 2015
Controversies in guidelines for the control of multidrug-resistant Gram-negative bacteria in EU countries.
Clin Microbiol Infect 2015 Jun 19

 

Oumouna, M., M. Weitnauer, V. Mijosek, L.M. Schmidt, T. Eigenbrod, A.H. Dalpke. 2015
Cell-contact dependent inhibition of monocytes by airway epithelial cells and reversion by infection with Respiratory Syncytial Virus.
Immunobiology 220: 1240-1245

  

Rimbach, K., S. Kaiser, M. Helm, A.H. Dalpke, T. Eigenbrod. 2015
2'-O-Methylation within Bacterial RNA Acts as Suppressor of TLR7/TLR8 Activation in Human Innate Immune Cells.
J Innate Immunity 7(5): 482-493

 

Rodriguez-Bano, J., M.D. Toro, J. Lopez-Delgado, N.T. Mutters, A. Pascual. 2015
Minimum requirements in infection control.
Clin Microbiol Infect 2015 Jun 19

 

Aline Sähr, Sandra Förmer, Dagmar Hildebrand, Klaus Heeg. 2015
T-cell activation or tolerization: the Yin and Yang of bacterial superantigens
Frontiers in Micorbiology doi:10.3389/fmicb.2015.01153

 

Senft, J.D., B. Carstensen, A. Mischnik, R. Warschkow, B.P Müller-Stich, G.R. Linke. 2015
Endolumenal colon occlusion reduces peritoneal contamination during a transrectal NOTES procedure: a controlled porcine survival study.
Surg Endosc DOI 10.1007/s00464-015-4582-2

 

Stammler, D., T. Eigenbrod, S. Menz, J.S. Frick, M.J. Sweet, M.R. Shakespear, J. Jantsch, I. Siegert, S. Wölfle, J.D. Langer, I. Oehme, L. Schaefer, A. Fischer, J. Knievel, K. Heeg, A.H. Dalpke, K.A. Bode. 2015 Inhibition of Histone Deacetylases Permits Lipopolysaccharide-Mediated Secretion of Bioactive IL-1ß via a Caspase-1-Independent Mechanism. J immunol doi:10.4049/jimmunol.1501195

 

Tanja Wiedenmann, Stefanie Ehrhardt, Daniela Cerny, Dagmar Hildebrand, Sabrina Klein, Klaus Heeg, Katharina F. Kubatzky. 2015
Erythropoietin acts as an anti-inflammatory signal on murine mast cells
Molecular Immunology 65:68-76

 

Zingg, W., N.T. Mutters, S. Harbarth, A.W. Friedrich. 2015
Education in Infection Control: a need for European certification.

Publikationen 2014

Bösel, J., S. Klein, B. Ellger. 2014

SOP Infektion

Intensivmedizin up2date 10: 278-281

 

Borg, M.A., M. Hulscher, E.A. Scicluna, J. Richards, J.M. Azanowsky, D. Xuereb, A. Huis, M.L. Moro, H.C. Maltezou, U. Frank. 2014

Prevention of methicillin-resistant Staphylococcus aureus bloodstream infections in European hospitals: moving beyond policies.

J Hosp Infect 87(4): 203-211

 

Brenner, T., T. Fleming, F. Uhle, S. Silaff, F. Schmitt, E. Salgado, A. Ulrich, S. Zimmermann, T. Bruckner, E. Martin, A. Bierhaus, P.P. Nawroth, M.A. Weigand, S. Hofer. 2014

Methylglyoxal as a new biomarker in patients with septic shock: an observational clinical study.

Crit Care 18(6): 683-693

 

Bretz, N.P., J. Ridinger, A.-K. Rupp, K. Rimbach, S. Keller, C. Rupp, F. Marmé, L. Umansky, V. Umansky, T. Eigenbrod, M. Sammar, P. Altevogt. 2014

Body fluid exosomes promote secretion of inflammatory cytokines in monocytic cells via TLR signaling.

J Biol Chem 288(51): 36691-36702

  

Burckhardt, I., J. Roemer, F. Burckhardt, S. Zimmermann. 2014

Serotyping of pneumococci: evaluation of the genetic approach and performance with clinical samples.

Diagn Micr Infec Dis 80(4): 274-277

 

Dalpke, A.H., M. Hofko, C. Stock, S. Zimmermann. 2014

Evaluation of the BD Max MRSA XT Assay for Use with Different Swab Types.

J Clin Microbiol  52(12): 4343-4346

 

Dapunt, U., B. Lehner, I. Burckhardt, S. Zimmermann, G.M. Hänsch, V. Ewerbeck. 2014

Evaluation of implant sonication as a diagnostic tool in implant-associated infections.

J Appl Biomater Func 12(3): 135-140

 

Dapunt, U., A. Mischnik, S. Goeppinger, B. Lehner. 2014

A persistent case of tuberculosis of the pubic symphysis and pubic bone.

BMJ Case Rep doi:10.1136/bcr-2013-203456

 

Franchi, L., T. Eigenbrod, R. Muñoz-Planillo, U. Ozkurede, Y.-G. Kim, A. Chakrabarti, M. Gale Jr., R.H. Silvermann, M. Colonna, S. Akira, G. Núñez. 2014

Cytosolic Double-Stranded RNA Activates the NLRP3 Inflammasome via MAVS-Induced Membrane Permeabilization an K+ Efflux.

J Immunol 193(8): 4214-4222

 

Gartiser, S., F. Flach, C. Nickel, M. Stintz, S. Damme, A. Schaeffer, L. Erdinger, T.A.J. Kuhlbusch. 2014

Behavior of nanoscale titanium dioxide in laboratory wastewater treatment plants according to OECD 303 A.

Chemosphere 104: 197-204

 

Gehrig, S., J. Duer, M. Weitnauer, C.J. Wagner, S.Y. Graeber, J. Schatterny, S. Hirtz, A. Belaaouaj, A.H. Dalpke, C. Schultz, M.A. Mall. 2014

Lack of neutrophil elastase reduces inflammation, mucus hypersecretion and amphysema, but not mucus obstruction, in mice with CF-like lung disease.

AJRCCM 189(9): 1082-1092

 

Giampaoli, S., N. Garrec, G. Donzé, F. Valeriani, L. Erdinger, V.R. Spica. 2014

Regulations concerning natural swimmingponds in Europe: considerations on public health issues.

J Water hHealth 12: 564-572

 

Hamoud, R., S. Zimmermann, J. Reichling, M. Wink. 2014

Synergistic interactions in two-drug and three-drug combinations (thymol, EDTA and vancomycin) against multi drug resistant bacteria uncluding E. coli.

Phytomedicine 21: 443-447

 

Heininger, A., U. Frank, P. Schnitzler. 2014

Maßnahmen zum Schutz vor kontaktübertragenen Virusinfektionen.

Krankenhaushyg.up2date 09(04): 233-253

 

Hildebrand, D., K.A. Bode, D. Rieß, D. Cerny, A. Waldhuber, F. Römmler, J. Strack, S. Korten, J.H. Orth, T. Miethke, K. Heeg, K.F. Kubatzky. 2014

Granzyme A Produces Bioactive IL-1β through a Nonapoptotic Inflammasome-Independent Pathway.

Cell Rep 9(3): 910-917

 

Hilmi, D., M. Parcina, D. Stollewerk, J. Ostrop, M. Josten, A. Meilaender, U. Zaehringer, T.A. Wichelhaus, G. Bierbaum, K. Heeg, C. Wolz, I. Bekeredjian-Ding. 2014

Heterogeneity of HOst TLR2 Stimulation by Staphylococcus aureus Isolates.

PLOS one 9(5): e96416

 

Hofko, M., A. Mischnik, M. Kaase, S. Zimmermann, A.H. Dalpke. 2014

Detection of Carbapenemases by Real-Time PCR and Melt Curve Analysis on the BD MAX System.

J Clin Microbiol 52(5): 1701-1704

 

Jakob, E., R. Max, S. Zimmermann, A.H. Dalpke, W. Alle, M. Becker, F. Mackensen. 2014

Three Years of Experience with QuantiFERON-TB Gold Testing in Patients with Uveitis.

Ocul Immunol & Inflamm 22(6): 478-484

 

Kaier K., M.L. Lambert, U.K. Frank, W. Vach, M. Wolkewitz, E. Tacconelli, J. Rello, U. Theuretzbacher, M. Martin. 2014

Impact of availability of guidelines and active surveillance in reducing the incidence of ventilator-associated pneumonia in Europe and worldwide.

BMC Infect Dis 14: 199-207

 

Kaiser, S., K. Rimbach, T. Eigenbrod, A.H. Dalpke, M. Helm. 2014

A modified dinucleotide motif specifies tRNA recognition by TLR7.

RNA 20: 1351-1355

 

Krause, L., F. Mackensen, U. Pleyer, C.-D. Quentin, F. Seibel, S. Zimmermann. 2014

Infektiös.

In: Entzündliche Augenerkrankungen, Ed.: U. Pleyer, ISBN: 978-3-642-38419-6, Springer-Verlag Berlin Heidelberg, 287-306

  

Krueger, W.A., A. Heininger, B. Grabein, K. Unertl, M. Sánchez-García. 2014

Selective Digestive Tract Decontamination and Spread of Colistin Resistance: Antibiotic Prophylaxis Is Not a Substitute for Hygiene.

Antimicrob Agents Ch 58(6): 3574-3575

 

Mischnik, A., J. Stockklausner, N. Hohneder, H.E. Jensen, S. Zimmermann, D.E. Reuss, V. Rickerts, K. Tintelnot, C. Stockklausner. 2014

First case of disseminated cryptococcosis in a Gorilla gorilla.

Mycoses 57(11): 664-671

 

Mutters, N.T. 2014

Laboratory Automation in Clinical Microbiology: A Quiet Revolution.

Austin J Infect Dis 1(1): 2

 

Mutters, N.T., F. Günther, A. Heininger, U. Frank. 2014

Device-related infections in long-term healthcare facilities: the challenge of prevention.

Future Microbiol 9(4): 487-495

 

Mutters, N.T., U. Hägele, D. Hagenfeld, E. Hellwig, U. Frank. 2014

Compliance with infection control practices in an university hospital dental clinic.

GMS Hyg Infect Control 9(3): Doc18

 

Mutters, N.T., C.J. Hodiamont, M.D. de Jong, H.P.J. Overmeijer, M. van den Boogaard, C.E. Visser. 2014

Performance of Kiestra Total Laboratory Automation Combined with MS in Clinical Microbiology Practice.

Ann Lab Med 34: 111-117

 

Mutters, N.T., E. Meyle. 2014

Amoxicillin: Pharmaceutical Properties and Clinical Applications.

In: Amoxicillin - Medical Uses, Mechanism of Action and Potential Adverse Effects, Eds.: W.A. Leary, L.M. Kruse, ISBN: 978-1-62948-489-1, Nova Biomedical, New York, 83-100

 

Rohde, D., C. Schön, M. Boerries, I. Didrihsone, J. Ritterhoff, K.F. Kubatzky, M. Völkers, N. Herzog, M. Mähler, J.N. Tsoporis, T.C. Parker, B. Linke, E. Giannitsis, E. Gao, K. Peppel, H.A. Katus, P. Most. 2014

S100A1 is released from ischemic cardiomyocytes and signals myocardial damage via Toll-like receptor 4.

EMBO Mol Med 6: 778-794

 

Rupp, C., K.A. Bode, F. Chahoud, A. Wannhoff, K. Friedrich, K.-H. Weiss, P. Sauer, W. Stremmel, D.N. Gotthardt. 2014

Risk factors and outcome in patients with primary sclerosing cholangitis with persistent biliary candidiasis.

BMC Infectious Diseases 14: 562-570

 

Schneeberg, A., R. Ehricht, P. Slickers, V. Baier, H. Neubauer, S. Zimmermann, D. Rabold, A. Lübke-Becker, C. Seyboldt. 2014

DNA microarray based PCR ribotyping Clostridium difficile.

J Clin Microbiol 53(2): 433-442

 

Tacconelli, E., M.A. Cataldo, S.J. Dancer, G. De Angelis, M. Falcone, U. Frank, G. Kahlmeter, A. Pan, N. Petrosillo, J. Rodriguez-Bano, N. Singh, M. Venditti, D.S. Yokoe, B. Cookson. 2014

ESCMID guidelines for the management of the infection control measures to reduce transmission of multidrug-resistant Gramnegative bacteria in hospitalized patients.

Clin Microbiol Infect Suppl 1: 1-55

 

Weitnauer, M., L. Schmidt, N.N. Kuet Leong, S. Muenchau, F. Lasitschka, V. Eckstein, S. Hübner, J. Tuckermann, A.H. Dalpke. 2014

Bronchial Epithelial Cells Induce Alternatively Activated Dendritic Cells Dependent on Glucocorticoid Receptor Signaling.

J Immunol 93(3): 1475-1484

 

Wolkewitz, M., A.G. Barnett, M. Palomar Martinez, U. Frank, M. Schumacher for the IMPLEMENT Study Group. 2014

Interventions to control nosocomial infections: study designs and statistical issues.

J Hosp Infect 86: 77-82

 

Ziegler, S., K. Gartner, U. Scheuermann, T. Zoeller, J. Hantzschmann, B. Over, S. Foermer, K. Heeg, I. Bekeredjian-DIng. 2014

Ca(2+)-related signaling events influence TLR9-induced IL-10 secretion in human B cells.

Eur J immunol 44: 1285-1298

 

Publikationen 2013

Astani, A., S. Zimmermann, E. Hassan, J. Reichling, K.H. Sensch, P. Schnitzler. 2013

Antimicrobial activity of propolis extract against multidrug-resistant clinical isolates.

Pharmazie 68: 1-7

 

Beikert, F.C., Z. Anastasiadou, B. Fritzen, U. Frank, M. Augustin. 2013

Topical treatment of tinea pedis using 6% coriander oil in unguentum leniens: a randomized, controlled, comparataive pilot study.

Dermatology 226(1): 47-51

 

Brooke, R.J., M.E. Kretzschmar, N.T. Mutters, P.F. Teunis. 2013

Human dose response relation for airborne exposure to Coxiella burnetii.

BMC Infect Dis 13(1): 488

 

Burckhardt, I. 2013

Intrafamily Transmission of Streptococcus pneumoniae and the Protective Power of Vaccination.

Epidemiol 3(4): 1000138

 

Conrad, A., D. Biehler, T. Nobis, H. Richter, I. Engels, K.Biehler, U. Frank. 2013

Broad spectrum antibacterial activity of a mixture of isothiocyanates from nasturtium (Tropaeoli majoris herba) and horseradish (Armoraciae rusticanae radix).

Drug Res 63(2): 65-68

 

Dalpke, A.H., M. Hofko, S. Zimmermann. 2013

Development and Evaluation of a Real-Time PCR Assay for Detection of Pneumocystis jirovecii on the Fully Automated BD MAXTM Platform.

J Clin Microbiol  51(7): 2337-2343

 

Dalpke, A.H., M. Hofko, M. Zorn, S. Zimmermann. 2013

Evaluation of th Fully automated BD MAX Cdiff and Xpert C. difficile Assays for Direct Detection of Clostridium difficile in Stool Specimens.

J Clin Microbiol 51(6): 1906-1908

 

Doster, A., S. Ziegler, S. Foermer, R.J. Rieker, K. Heeg, I. Bekeredjian-Ding. 2013

PTO-modified CpG oligodeoxynucleotides mimic autoantigens and reveal a potential role for TLR9 in receptor revision.

Immunology 139(2): 166-178

 

Eigenbrod, T., K.A. Bode, A.H. Dalpke. 2013

Early Inhibition of IL-1ß Expression by IFN-γ Is Mediated by Impaired Binding of NF-κB to the IL-1ß Promotor but Is Independent of Nitric Oxide.

J Immunol  190: 6533-6541

 

Eigenbrod, T., A.H. Dalpke. 2013

TLR7 inhibition - A novel strategy for pancreatic cancer treatment?

Jak-Stat 2(1): 1-4

 

Geis, S.,C. Prifert, B. Weissbrich, N. Lehners, G. Egerer, C. Eisenbach, U. Buchholz, E. Aichinger, P. Dreger, K. Neben, U. Burkhardt, A.D. Ho, H.-G. Kräusslich, K. Heeg, P. Schnitzler. 2013

Molecular Characterizatin of a Respiratory Syncytial Virus Outbreak in a Hematology Unit in Heidelberg, Germany.

J Clin Microbiol 51(1): 155-162

 

Gotthardt, D.N., K.H. Weiss, C. Rupp, K. Bode, I. Eckerle, G. Rudolph, J. Bergemann, P. Kloeters-Plachky, F. Chahoud, M.W. Büchler, P. Schemmer, W. Stremmel, P. Sauer. 2013

Bacteriobilia and fungibilia are associated with outcome in patients with endoscopic treatment of biliary complications after liver transplantation.

Endoscopy 45:890-896

 

Gumbinger, C., A. Hug, B. Mürle, B. Berger, M. Zorn, K.P. Becker. S. Zimmermann, A.H. Dalpke, R. Veltkamp. 2013

Early blood-based microbiological testing is ineffective in severe stroke patients.

J Neurol Sci 325(1-2): 46-50

 

Hilmi, D., M. Parcina, K. Bode,J. Ostrop, S. Schuett, K. Heeg, W. Ziebuhr, O. Sommerburg, I. Bekeredjian-Ding. 2013

Functional variation reflects intra-strain diversity of Staphylococcus aureus small colony variants in the host-pathogen interaction.

Int J Med Microbiol 303: 61-69

 

Kaier, K., U. Frank. 2013

In search of useful methods for measuring health and economic consequences of antimicrobial resistance.

Clin Infect Dis 57(8): 1220-1222

 

Koschny, R., T. Junghanss, A. Mischnik, M. Karner, M. Kreuter, W. Roth, W. Stremmel, U. Merle, 2013

Development of Miliary Tuberculosis under Infliximab in a Patient with Spondyloarthritis and Suspected Crohn's Disease.

Z Gastroenterol 51: 1177-1183

 

Kubatzky, K.F., B. Kloos, D. Hildebrand. 2013

Signaling cascades of Pasteurella multocida toxin in immune evasion.

Toxins 5(9): 1664-1681

 

Lambert, M.-L., M. Palomar, A. Agodi, M. Hiesmayr, A. Lepape, A. Ingenbleek, E.P. Herrejon, S. Blot, U. Frank. 2013

Prevention of ventilator-associated pneumonia in intensive care units: an international online survey.

Antimicrob Resist Infect Control 2: 9

 

Lehners, N., P. Schnitzler, S. Geis, J. Puthenparambil, M.A. Benz, B. Alber, T. Luft, P. Dreger, C. Eisenbach, C. Kunz, A. Benner, U. Buchholz, E. Aichinger, U. Frank, K. Heeg, A.D. Ho, G. Egerer. 2013

Risk factors and containment of respiratory syncytial virus outbreak in a hematology and transplant unit.

Bone Marrow Transplant 48(12): 1548-153

 

Liesz, A., H. Rüger, J. Purrucker, M. Zorn, A. Dalpke, M. Möhlenbruch, S. Englert, P.P. Nawroth, R. Veltkamp. 2013

Stress Mediators and Immune Dysfunction in Patients with Acute Cerebrovascular Diseases.

PLoS One 8(9): e74839

 

Mischnik, A., S. Klein, K. Tintelnot, S. Zimmermann, V. Rickerts. 2013

Kryptokokkose: Kasuistiken, Epidemiologie und Therapiestrategien.

Dtsch Med Wochenschr 138(30): 1533-1538

 

Mutters, N.T., R.J. Brooke, U. Frank, K. Heeg. 2013

Low risk of apparent transmission of vancomycin-resistant Enterococci from bacteraemic patients to hospitalized contacts.

Am J Infect Control 41(9): 778-781

 

Mutters, N.T., U. Frank. 2013

Sources of systematic errors in the epidemiology of vancomycin-resistant enterococci.

Infection 41(2): 305-310

 

Mutters, N.T., V. Mersch-Sundermann, R. Mutters, C. Brandt, W. Schneider-Brachert, U. Frank. 2013

Control of th Spread of Vancomycin-Resistant Enterococci in Hospitals: Epidemiology and Clinical Relevance.

Dtsch Arztebl Int 110(43): 725-731

 

Mutters, N.T., S. Stoffels, C. Eisenbach, S. Zimmermann. 2013

Ischaemic intestinal perforation complicated by Clostridium perfringens sepsis in a diabetic patient.

Infection 41: 1033-1035

 

Over, B., S. Ziegler, S. Foermer, A.N.R. Weber, K.A. Bode, K. Heeg, I. Bekeredjian-Ding. 2013

IRAK4 turns IL-10+ phospho-FOXO+ monocytes into pro-inflammatory cells by suppression of protein kinase B.

Eur J Immunol  43: 1630-1642

 

Parcina, M., M.A. Miranda-Garcia, S. Durlanik, S. Ziegler, B. Over, P. Georg, S. Foermer, S. Ammann, D. Hilmi, K.-J. Weber, M. Schiller, K. Heeg, W. Schneider-Brachert, F. Götz, I. Bekeredjian-Ding. 2013

Pathogen-Triggered Activation of Plasmacytoid Dendritic Cells Induces IL-10-Producing B Cells in Response to Staphylococcus aureus.

J Immunol 190(4): 1591-1602

 

Perovic, S., A. Perovic, L. Erdinger, H. Hollert. 2013

Assessment of the mutagenic potential of skadar lake sediments using the Salmonella microsomal assay.

Arch Biol Sci (Belgrade) 65(3): 1189-1194

 

Schneeberg, A., H. Neubauer, G. Schmoock, S. Baier, J. Harlizius, H. Nienhoff, K. Brase, S. Zimmermann, C.Seyboldt. 2013

Clostridium difficile Genotypes in Piglet Populations in Germany.

J Clin Microbiol  51(11): 3796-3803

 

Scholz, T., C.L. Heyl, D. Bernardi, S. Zimmermann, L. Kattner, C.D. Klein. 2013

Chemical, biochemical and microbiological properties of a brominated nitrovinylfuran with broad-spectrum antibacterial activity.

Bioorg. Med. Chem. 21: 795-804

 

Steinebrunner, N., C. Sandig, S. Zimmermann, W. Stremmel, C. Eisenbach, A. Mischnik. 2013

Salmonella enterica serovar Minnesota urosepsis in a patient with Crohn's disease in the absence of recent or curent gastrointestinal symptoms.

J Med Microbiol 62: 1360-1362

 

Suda, A.J., M. Kommerell, H.K. Geiss, I. Burckhardt, S. Zimmermann, F. Zeifang, B. Lehner. 2013

Prosthetic infection: Improvement of diagnostic procedures using 16S ribosomal deoxyribonucleic acid polymerase chain.

International Orthopaedics (SICOT) 37: 2515-2521

 

Ziegler, S., M.E. Eberle, S.J. Wölfle, K. Heeg, I. Bekeredjian-Ding. 2013

Bifunctional Oligodeoxynucleotide/AntagomiR Constructs: Evaluation of aNew Tool for MicroRNA Silencing.

Nucleic Acid Therapeutics 23: 427-434

 

Zimmermann, S., E. Hadaschik, A. Dalpke, J. Hassel, D. Ajzenberg, K. Tenner-Racz, N. Lehners, A. Kapaun, P. Schnitzler. 2013

Varicella-like cutaneous toxoplasmosis in a patient with aplastic anemia.

J Clin Microbiol 51(4): 1341-1344

 

 

Publikationen 2012

Bekeredjian-Ding, I., S. Foermer, C.J. Kirschning, M. Parcina, K. Heeg. 2012

Poke Weed Mitogen Requires Toll-like Receptor Ligands for Proliferative Activity in Human and Murine B Lymphocytes.

PLoS ONE 7(1): e29806. doi:10.1371/journal.pone.0029806

 

Dalpke, A.H., M. Helm. 2012

RNA mediated Toll-like receptor stimulation in health and disease.

RNA Biol 9(6): 828-842

 

Dalpke, A.H., M. Hofko, S. Zimmermann. 2012

Comparison of the BD MAX MRSA Assay and the BD GeneOhm MRSA Achromopeptidase Assay for the Detection of Methicillin-Resistant Staphylococcus aureus against Direct and Enriched Culture Techniques in Clinical Specimens.

J Clin Microbiol 50(10): 3365-3367

 

Eberle, M.E., A.H. Dalpke. 2012

Dectin-1 Stimulation Induces Seppressor of Cytokine Signaling 1, Thereby Modulating TLR Signaling and T Cell Responses.

J Immunol 188(11): 5644-5654

 

Eigenbrod, T., L. Franchi, R. Munoz-Planillo, C.J. Kirschning, M.A. Freudenberg, G. Nunez, A. Dalpke. 2012

Bacterial RNA Mediates Activation of Caspase-1 and IL-1ß Release Independently of TLRs 3, 7, 9 and TRIF but Is Dependent on UNC93B.

J Immunol  189: 328-336

 

Gehrig, S., M.E. Eberle,F. Botschen, K. Rimbach, F. Eberle, T. Eigenbrod, S. Kaiser, W.M. Holmes, V.A. Erdmann, M. Sprinzl, G. Bec, G. Keith, A.H. Dalpke*, M. Helm*. 2012

Identification of modifications in microbial, native tRNA that suppress immunostimulatory activity.

J Exp Med 209(2): 225-233 *equal contribution

 

Ginter, T., C. Bier, S.K. Knauer, K. Sughra, D. Hildebrand, T. Münz, T. Liebe, R. Heller, A. Henke, R.H. Stauber, W. Reichardt, J.A. Schmid, K.F. Kubatzky, T. Heinzel, O.H. Krämer. 2012

Histone deacetylase inhibitors block IFNy-induced STAT1 phosphorylation.

Cell Signal 24(7): 1453-1460

 

Hidmark, A., A.v. Saint Paul, A.H. Dalpke. 2012

Cutting Edge: TLR13 Is a Receptor for Bacterial RNA.

J Immunol 189: 2717-2721

 

Hildebrand, D., A. Sähr, S.J. Wölfle, K. Heeg*, K.F. Kubatzky*. 2012

Regulation of Toll-like receptor 4-mediated immune responses through Pasteurella multocida toxin-induced G protein signalling.

Cell Communication and Signaling 10(22): 1-15 *equal contribution

 

Jennemann, R., M. Rabionet, K. Gorgas, S. Epstein, A. Dalpke, U. Rothermel, A. Bayerle, F. van der Hoeven, S. Irmgrund, J. Kirsch, W. Nickel, K. Willecke, H. Riezmann, H.-J. Gröne, R. Sandhoff. 2012

Loss of ceramide synthase 3 causes lethal skin barrier disruption.

Hum Mol Genet 21(3): 586-608

 

Kaier, K., N.T. Mutters, U. Frank. 2012

Bed occupancy rates and hospital-acquired infections - should beds be kept empty?

Clin Micribiol Infect 18(10): 941-945

 

Kaier, K., C. Wilson, M. Hilscher, H. Wollersheim, A. Huis, M. Borg, E. Scicluna, M.-L. Lambert, M. Palomar, E. Tacconelli, F. DeAngelis, M. Schumacher, M. Wolkewitz, E.-M. Kleissle, U. Frank. 2012

Implementing strategic bundles for infection prevention and management.

Infection 40(2): 225-228

 

Klein*, S., S. Zimmermann*, C. Köhler, A. Mischnik, W. Alle, K. Bode. 2012

Integration of matrix-assisted laser desorption/ionization time-of-flight mass spectrometry in blood culture diagnostics: a fast and effective approach.

J Med Microbiol 61: 323-331 *equal contribution

 

Knezevic, J., D. Pavlinic, W.A. Rose, C.A. Leifer, K. Bendelja, J. Gabrilovac, M. Parcina, G. Lauc, A.V. Kubarenko, B. Petricevic, D.Vrbanec, L. Bulat-Kardum, I. Bekeredjian-Ding, J. Pavelic, Z. Dembic, A.N. Weber. 2012

Heterozygous carriage of a dysfunctional TLR9 allele affects CPG-oligonucleotide responses in B cells.

J Biol Chem 287: 24544-24553

 

Kubatzky, K.F. 2012

Pasteurella Multocida and Immune Cells.

Curr Top Microbiol Immunol 361: 53-72

 

Lehner, B., M. Akbar, C. Rehnitz, G.W. Omlor, U. Dapunt, I. Burkhardt. 2012

Standards der mikrobiologischen Diagnostik der Spondylodiszitis.

Orthopädie 41: 702-710

 

Louis-Dit-Sully, C., K.F. Kubatzky, J.A. Lindquist, C. Blattner, O. Janssen, W.W. Schamel. 2012

Meeting report signal transduction meets systems biology.

Cell Commun Signal 10: 11

 

Mischnik, A., T. Dahme, R. Bekeredjian, S. Zimmermann. 2012

Haemophilia-associated Yersinia pseudotuberculosis serotype O:1 septicaemia: the role of iron.

J Med Microbiol61: 157-159

 

Mischnik, A., M. Mieth, C.J. Busch, S. Hofer, S. Zimmermann. 2012

First evaluation of PREVI Isola automated specimen inoculation for wound swab samples compared to manual inoculation in a routine laboratory. A cost-effective and accurate approach.

J Clin Microbiol 50: 2732-2736

 

Mutters, N.T. 2012

Infektiologie: Konkurrenzloses Standardwerk.

Dtsch Arztebl 109/31-32: A1560

 

Perovic, A., S. Perovic, L. Erdinger, H. Hollert. 2012

Assessment of the genotoxic potential of lake skadar sediments using ames test and comet assay on the fish cell line RTL-W1.

Arch Biol Sci Belgrade 64(1): 249-256

 

Reipschlaeger, S., K. Kubatzky, S. Taromi, M. Burger, J. Orth, K. Aktories, G. Schmidt. 2012

Toxin-induced RhoA activity mediates CCL1-triggered STAT signaling.

J Biol Chem 287: 11183-11194

 

Sangaré, L., A.K. Nikiéma, S. Zimmermann, I. Sanou, M. Congo-Ouédraogu, A. Diabaté, S. Diandé, P.I. Guissou. 2012

Campylobacter spp. epidemiology and antimicrobial susceptibility in a developing country, Burkina Faso (West Africa).

Afr J clin exper microbiol 13(2): 106-111

 

Schiller, M., M. Parcina, P. Heyder, S. Foermer, J. Ostrop, A. Leo, K. Heeg, H.M. Lorenz, I. Bekeredjian-Ding. 2012

Induction of Type I IFN Is a Physiological Reaction to Apoptotic Cell-Derived Membrane Microparticles.

J Immunol 189: 1747-1756

 

Strebovsky, J., A.H. Dalpke. 2012

SOCS

In: Encyclopedia of Signaling Molecules. Choi, Sangdun (Ed.), Springer New York, part20, 1753-1759, ISBN 978-1-4419-0460-7 (print)

 

Strebovsky, J., P. Walker, A.H. Dalpke. 2012

Suppressor of cytokine signaling proteins as regulators of innate immune signaling.

Front Biosci 17: 1627-1639

 

Stutz, A., H. Kessler, M.E. Kaschel, M. Meissner, A.H. Dalpke. 2012

Cell invasion and strain dependent induction of Suppressor of Cytokine Signaling-1 by Toxoplasma gondii.

Immunobiol 217: 28-36

 

Wetterauer, B., M. Ricking, J.C. Otte, A.V. Hallare, A. Rastall, L. Erdinger, J. Schwarzbauer, T. Braunbeck, H. Hollert. 2012

Toxicity, dioxin-like activities,and endocrine effects of DDT metabolites - DDA, DDMU, DDMS, and DDCN.

Environ Sci Pollut Res 19: 403-415

 

Zeitvogel, J., A. Dalpke, B. Elz-Vesper, M. Kracht, O. Dittrich-Breiholz, T. Werfel, M. Wittmann. 2012

Human primary keratinoctes show a restricted ability to up-regulate Suppressor of Cytokine Signaling (SOCS)3 compared to autologous macrophages.

J Biol Chem : Epub ahead of priniting PMID: 22294695

Publikationen 2011

Binder, M., F. Eberle, S. Seitz, N. Mücke, C.M. Hüber, N. Kiani, L. Kaderali, V. Lohmann, A. Dalpke, R. Bartenschlager. 2011

Length-Dependent and 5'-Triphosphate-Independent Recognition of Double-Stranded RNA by Retinoic Acid Unducible Gene I. 

J Biol Chem 286(31): 27278-27287

 

Bode, K.A., A.H. Dalpke. 2011

HDAC inhibitors block innate immunity. (Comment)

Blood 117(4): 1102-1103

 

Burckhardt, I., S. Zimmermann. 2011

Streptococcus pneumoniae in Urinary Tracts of Children with Chronic Kidney Disease.

Emerging Infectious Diseases 17(1): 120-122 

 

Burckhardt, I., S. Zimmermann. 2011

Using Matrix-Assisted Laser Desorption Ionization-Time of Flight Mass Spectrometry To Detect Carbapenem Resistance within 1 to 2.5 Hours.

J Clin Microbiol 49(9): 3321-3324

 

Ehlting, C., N. Ronkina, O. Böhmer, U. Albrecht, K.A. Bode, K.S. Lang, A. Kotlyarov, D. Radzioch, M. Gaestel, D. Häussinger, J.G. Bode.2011

Distinct functions of the mapkap kinases MK2 and MK3: MK2 mediates LPS-induced STAT3 activation by preventing negative regulatory effects of MK3.

J Biol Chem 286(27): 24113-24124

 

Erdinger, L., H. Hollert, P. Eckl. 2011

Aral Sea: An Ecological Disaster Zone with Impact on Human Health.

In: Encyclopedia of Environmental Health, Five-Volume Set, 1st Edition

Elsevier Science, ISBN 9780444522733

 

Erikson, E., T. Adam, S. Schmidt, J. Lehmann-Koch, B. Over, C. Goffinet, C. Harter, I. Bekeredjian-Ding, S. Sertel, F. Lasitschka, O.T. Keppler. 2011

In vivo expression profile of the antiviral restriction factor and tumor-targeting antigen CD317/BST-2/HM1.24/tetherin in humans.

PNAS: P Natl Acad Sci USA 108(33): 13688-13693

 

Haas, J., I. Bekeredjian-Ding, M. Milkova, B. Balint, A. Schwarz, M. Korporal, S. Jarius, B. Fritz, H.-M. Lorenz, B. Wildemann. 2011

B cells undergo unique compartmentalized redistribution in multiple sclerosis.

J Autoimmun 37(4): 289-299

 

Hildebrand, D., K. Heeg, K.F. Kubatzky. 2010

Pasteurella multocida Toxin-stimulated osteoclast differentiation is B cell dependent.

Infect Immun 79: 220-228

 

Hug, A., A. Liesz, B. Muerle, W. Zhou, J. Ehrenheim, A. Lorenz, A. Dalpke, R. Veltkamp. 2011

Reduced Efficacy of Circulating Costimulatory Cells After Focal Cerebral Ischemia.

Stroke 42(12): 3580-3586

 

Hug, A., B. Mürle, A. Dalpke, M. Zorn, A. Liesz, R. Veltkamp. 2011

Usefullness of Serum Procalcitonin Levels for the early Diagnosis of Stroke associated Respiratory Tract Infections.

Neurocrit Care 14(3): 416-422

 

Illanes, S., A. Liesz, L. Sun, A. Dalpke, M. Zorn, R. Veltkamp. 2011

Hematoma size as major modulator of the cellular immune system after experimental intracerebral hemorrhage.

Neurosci Lett 490(3): 170-174

 

Kurz, J., F. Eberle, T. Graumann, M.-E. Kaschel, A. Sähr, F. Neumann, A.H. Dalpke, L. Erdinger. 2011

Inactivation of LPS and RNase A on photocatalytically active surfaces.

Chemosphere 84: 1188-1193

 

Liesz, A., W. Zhou, E. Mracsko, S. Karcher, H. Bauer, S. Schwarting, L. Sun, D. Bruder, S. Stegemann, A. Cerwenka, C. Sommer, A.H. Dalpke, R. Veltkamp. 2011

Inhibition of lymphocyte trafficking shields the brain against deleterious neuroinflammation after stroke.

Brain 134(3): 704-720

 

Mackensen, F., S. Zimmermann, W. Alle, R. Max, E. Jakob, M.D. Becker, D. Thiemeyer. 2011

Difficulties of Interpreting Borrelia Serology in Patients with Uveitis.

Ocul Immunol Inflamm 19(4): 227-231

 

Mischnik, A., S. Zimmermann, I. Bekeredjian-Ding, M. Egermann. 2011

Relaps of posttraumatic osteomyelitis due to Clostridium celerecrescens.

Infection 39(5): 491-494

 

Mutters, N.T. 2011

Klinische Mikrobiologie und Hygiene: Rollenfindung zwischen Kommerz und Public Health.

Dtsch Ärztebl 108(25): A1426-A1427

 

Schmidt, L., M.G. Belvisi, K.A. Bode, J. Bauer, C. Schmidt, M.-T. Suchy, D. Tsikas, J. Scheuerer, F. Lasitschka, H.-J. Gröne, A.H. Dalpke. 2011

Bronchial Epithelial Cell-Derived Prostaglandin E2 Dampens the Reactivity of Dendritic Cells.

J Immunol 186(4): 2095-2105

 

Strebovsky, J., P. Walker, R. Lang, A.H. Dalpke. 2011

Suppressor of cytokine signaling 1 (SOCS1) limits NF(kappa)B signaling by decreasing p65 stability within the cell nucleus.

FASEB J 25(3): 863-874

 

Thomas, B.C., S. Zimmermann, H.-E. Völcker, G.U. Auffarth, S. Dithmar. 2011

Severe Arthrographis kalrae Keratomycosis in an Immunocompetent Patient.

Cornea 30: 364-366

 

Woelfle, S., J. Strebovsky, H. Bartz, A. Sähr, C. Arnold, C. Kaiser, A. Dalpke, K. Heeg. 2011

PD-L1 expression on tolerogenic APCs is controlled by STAT-3.

Eur J Immunol 41: 413-424

 

Wölz, J., K. Grosshans, G. Streck, T. Schulze, A. Rastall, L. Erdinger, W. Brack, M. Fleig, D. Kühlers, T. Braunbeck, H. Hollert. 2011

Estrogen receptor mediated activity in bankside groundwater, with flood suspended particulate matter and Floodplain soil - An Approach combining tracer substance, bioassay and target analysis.

Chemosphere 85: 717-723

 

Zhou, Z., J. Duerr, B. Johannesson, S.C. Schubert, D. Treis, M. Harm, S.Y. Graeber, A. Dalpke, C. Schultz, M.A. Mall. 2011

The ßENaC-overexpressing mouse as a model of cystic fibrosis lung disease.

Journal of Cystic Fibrosis 10(Suppl 2): S172-S182

Publikationen 2010

Brockmann, S., I. Piecholowski, O. Bock-Hensley, C. Winter, R. Oehme, S. Zimmermann, K. Hartelt, E. Luge, K. Nockler, T. Schneider, K. Stark, A. Jansen. 2010

Outbreak of leptospirosis among triathlon participants in Germany, 2006.

BMC Infect Dis 10: 91 (5 pages)

 

Burckhardt, I., F. Burckhardt, M. van der Linden, C. Heeg, R.R. Reinert. 2010

Risk factor analysis for pneumococcal meningitis in adults with invasive pneumococcal infection.

Epidemiol Infect 138(9): 1353-1358

 

Dalpke, A.H. 2010

Mikrobiologische und immunologische Konzepte als Grundlage zur Bewertung von Impfungen.

Präv Gesundheitsf 5: 33-37

 

Dalpke, A.H. 2010

Impfungen - neue Erkenntnisse aus der Grundlagenforschung

MMW Fortschr Med 152/2: 42-46

 

Eckerle, I., S. Zimmermann, A. Kapaun, T. Junghanss. 2010

Salmonella enterica Serovar Virchow Bacteremia Presenting as Typhoid-Like Illness in an Immunocompetent Patient.

J Clin Microbiol 48(7): 2643-2644

 

Fritz, S., T. Hackert, W. Hartwig, F. Rossmanith, O. Strobel, L. Schneider, K. Will-Schweiger, M. Kommerell, M.W. Büchler, J. Werner. 2010

Bacterial translocation and infected pancreatic necrosis in acute necrotizing pancreatitis derives from small bowel rather than from colon.

American Journal of Surgery 200: 111-117

 

Fürstenberg, C.H., B. Wiedenhöfer, C. Putz, I. Burckhardt, S. Gantz, K. Kleinschmidt, K. Schröder. 2010

Mit Gentamicin oder Levofloxacin gesättigter Kollagenhydroxyapatit (Healos®).

[Collagen hydroxyapatite (Healos) saturated with gentamicin or levofloxacin. In vitro antimicrobial effectiveness - a pilot study]

Orthopäde 39: 437-443

 

Gündogdu, M., H. Liu, D. Metzdorf, D. Hildebrand, M. Aigner, K. Aktories, K. Heeg, K.F. Kubatzky. 2010

The haematopoitic GTPase RhoH modulates IL3 signalling through regulation of STAT activity and IL3 receptor expression.

Mol cancer 9: 225 (13 pages)

 

Hildebrand, D., P. Walker, A. Dalpke, K. Heeg, K.F. Kubatzky. 2010

Pasteurella multocida Toxin-induced Pim-1 expression disrupts suppressor of cytokine signalling (SOCS)-1 activity.

Cell Microbiol 12(12): 1732-1745

 

Kristen, A.V., S. Zimmermann, B.M. Helmke, W. Hosch, H.A. Katus, F.J. Meyer. 2010

60-jährige Patientin mit Raumforderung im rechten Lungenoberlappen nach Herztransplantation.

Internist 51: 207-212

 

Kubarenko, A.V., S. Ranjan, A. Rautanen, T.C. Mills, S. Wong, F. Vannberg, M. Neumaier, I. Bekeredjian-Ding, A.V. Hill, P. Ahmad-Nejad, A.N. Weber. 2010

A naturally occurring variant in human TLR9, P99L, is associated with loss of CpG oligonucleotide responsiveness.

J Biol Chem 285: 36486-36494

 

Mackensen, F., M. Becker, S. Zimmermann. 2010

Tuberculous Uveitis.

Ophthalmology 117(2): 401-402. Letters to the Editor

 

Preuss, I., D. Hildebrand, J.H. Orth, K. Aktories, K.F. Kubatzky. 2010

Pasteurella multocida toxin is a potent activator of anti-apoptotic signalling pathways.

Cell Microbiol 12(8): 1174-1185

 

Salvenmoser, S., M.J. Seidler, A. Dalpke, F.M. Müller. 2010

Effects of caspofungin, Candida albicans and Aspergillus fumigatus on toll-like receptor 9 of GM-CSF-stimulated PMNs.

FEMS Immunol Med Microbiol 60:74-77

 

Seifert, H., A. Dalhoff et PRISMA Study Group. 2010

German multicentre survey of the antibiotic susceptibility of Bacteroides fragilis group an Prevotella species isolated from intra-abdominal infections: results from the PRISMA study.

J Antimicrob Chemother 65 : 2405-2410

 

Thomas, B.C., S. Zimmermann, H.-E. Völcker, G.U. Auffarth, S. Dithmar. 2010

Severe Arthrographis kalrae Keratomycosis in an Immunocompetent Patient.

Cornea 30(3): 364-366

 

Ulrich, K., S. Wölfle, A. Mayer, K. Heeg, T. Braunbeck, L. Erdinger, H. Bartz. 2010

Extractable organic matter of Standard Reference Material 1649a influences immunological response induced by pathogen-associated molecular patterns.

Environ Sci Pollut Res 17: 1257-1267

 

Wendt, C., N.L. Havill, K.C. Chapin, J.M. Boyce, R. Dickenson, U. Eigner, S. Schütt, A.M. Fahr. 2010

Evaluation of a new selective medium, BD BBL CHROMagar MRSA II, for detection of methicillin-resistant Staphylococcus aureus in different specimens.

J Clin Microbiol 48(6): 2223-2227

 

Wendt, C., S. Schütt. 2010

Nachweis von Klebsiella pneumoniae-Carbapenemase in einem deutschen Krankenhaus.

Hyg Med 35(1/2): 21-25

 

Wendt, C., S. Schütt, A.H. Dalpke, M. Konrad, M. Mieth, B. Trierweiler-Hauke, M.A. Weigand, S. Zimmermann, K. Biehler, D. Jonas. 2010

First outbreak of Klebsiella pneumoniae carbapenemase (KPC)-producing K. pneumoniae in Germany.

Eur J Clin Microbiol Infect Dis 29(5): 563-565

 

Wensing, A., S. Zimmermann, K. Geider. 2010

Identification of the corn pathogen Pantoea stewartii by Mass Spectrometry of whole cell extracts and its detection with novel PCR primers.

Appl Environ Microbiol 76: 6248-6256

 

Zhou, Z., J. Duerr, B. Johannesson, S.C. Schubert, D. Treis, M. Harm, S.Y. Graeber, A. Dalpke, C. Schultz, M.A. Mall. 2010

The ßENaC-overexpressing mouse as a model of cystic fibrosis lung disease.

Journal of Cystic Fibrosis 9: Suppl. 3, S1-S11

Publikationen 2009

Bekeredjian-Ding, I., G. Jego. 2009

Toll-like Receptors - Sentries in the B-Cell Response.

Immunology 128: 311-323 Invited Review

 

Bekeredjian-Ding, I., M. Schäfer, E. Hartmann, R. Pries, M. Parcina, P. Schneider, T. Giese, S. Endres, B. Wollenberg, G. Hartmann. 2009

Tumour-derived prostaglandin E2 and transforming growth factor-β synergize to inhibit plasmacytoid dendritic cell-derived interferon-α.

Immunology 128: 439-450

 

Berger, M., A. Ablasser, S. Kim, I. Bekeredjian-Ding, T. Giese, S. Endres, V. Hornung, G. Hartmann. 2009

TLR8-driven IL-12-dependent Reciprocal and Synergistic Activation of NK Cells an Monocytes by Immunostimulatory RNA.

J Immunother 32(3): 262-271

 

Bock-Hensley, O., C. Wendt. 2009

MRSA im Pflegeheim. Was müssen Sie im Umgang mit dem Problemkeim beachten?

[Methicillin-resistant Staphylococcus aureus in nursing homes]

MMW Fortschr Med. 39: 41-46. German

 

Bode, K.A., F. Schmitz, L. Vargas, K. Heeg, A.H. Dalpke. 2009

Kinetic of RelA activation controls magnitude of Toll-like receptor mediatied IL-12p40 induction.

J Immunol 182(4): 2176-2184

 

Cookson, B., E. Mathai, B. Allegranzi, C.L. Pessoa-Silva, S. Bagheri Nejad, A. Schneider, C. Tschopp, C. Wendt, D. Pittet. 2009

Comparison of national and subnational guidelines for hand hygiene.

J Hosp Infect 72: 202-210

 

Dalpke, A.H. 2009

Immunologische Rationalen von Impfungen.

[Immunological basics of vaccination.]

Dtsch Med Wochenschr 134: 561-564. German

 

Eberle, F., M. Sirin, M. Binder, A.H. Dalpke. 2009

Bacterial RNA is recognized by different sets of immunoreceptors.

Eur J Immunol 39: 2537-2547

 

Heyder, P., I. Bekeredjian-Ding, S. Krienke, H.M. Lorenz, M. Schiller. 2009

Cells induced to undergo apo in the presens of the caspase inhibitor benzyloxycarbonyl-Val-Ala-Asp-fluoromethylketone stimulate Mo derived phagocytes to secrete proinflammatory cytokines.

Autoimmunity 42(4): 328-330

 

Hug, A., A. Dalpke, N. Wieczorek, T. Giese, A. Lorenz, G. Auffarth, A. Liesz, R. Veltkamp. 2009

Infarct Volume is a Major Determiner of Post-Stroke Immune Cell Function an Susceptibility to Infection.

Stroke 40(10): 3226-3232

 

Koelsche, C., J. Strebovsky, A. Baetz, A.H. Dalpke. 2009

Structural and functional analysis of a nuclear localization signal (NLS) in SOCS1.

Mol Immunol 46(13): 2474-2480

 

Krautter, U., M. Mory, C. Mogler, M. Schmaus, S. Zimmermann, K. Klemm, J. Debus, S. Oertel. 2009

Fatal Clostridium septicum Infection in a Patient with Non-Hodgkin's Lymphoma Undergoing Multimodal Oncologic Therapy.

Onkologie 32: 115-118

 

Kresken, M., E. Leitner, J. Brauers, H.K. Geiss, E. Halle, C. von Eiff, G. Peters, H. Seifert. 2009

Susceptibility of common aerobic pathogens to tigecycline: results of a surveillance study in Germany.

Eur J Clin Microbiol Infect Dis 28: 83-90

 

Liesz, A., S. Hagmann, C. Zschoche, J. Adamek, W. Zhou, L. Sun, A. Hug, M. Zorn, A. Dalpke, P. Nawroth, R. Veltkamp. 2009

The Spectrum of Systemic Immune Alterations After Murine Focal Ischemia, Immunodepression Versus Immunomodulation.

Stroke 40: 2849-2858

 

Mätz-Rensing, K., J. Winkelmann, T. Becker, I. Burckhardt, M. van der Linden, S. Köndgen, F. Leendertz, F.J. Kaup. 2009

Outbreak of Streptococcus equi subsp. zooepidemicus infection in a group of rhesus monkeys (Macaca mulatta).

J Med Primatol 38(5): 328-334

  

Meesmann, H.M., M. Parcina, H.M. Lorenz, N. Blank, M. Schiller. 2009

Apo mterial as a trigger for inflammation in systemic lupus erythematosus.

Autoimmunity 42(4): 251-253

 

Olbert, P.J., A.J. Schrader, C. Simon, A. Dalpke, P. Barth, R. Hofmann, A. Hegele. 2009

In Vitro and in Vivo Effects of CpG-Oligodeoxynucleotides (CpG-ODN) on Murine Transitional Cell Carcinoma and on the Native Murine Urinary Bladder Wall.

Anticancer Res. 29(6): 2067-2076

 

Parcina, M., M. Schiller, A. Gierschke, K. Heeg, I. Bekeredjian-Ding. 2009

PDC expression CD36, CD61 and IL-10 may contribute to propagation of immune tolerance.

Autoimmunity 42(4): 353-355

 

Peter, M.E., A.V. Kubarenko, A.N.R. Weber, A.H. Dalpke. 2009

Identification of an N-Terminal Recognition Site in TLR9 That Contributes to CpG-DNA-Mediated Receptor Activation.

J Immunol 182(12): 7690-7697

 

Rosenhagen, M., R. Feldhues, J. Schmidt, T. Hoppe-Tichy, H.K. Geiss. 2009

A Risk Profile for Invasive Aspergillosis in Liver Transplant Recipients.

Infection 37: 313-319

 

Swoboda, S., L. Helbig, M. Kommerell, H.G. Simank, F. Kees, H.K. Geiss, T. Hoppe-Tichy, K. Schröder. 2009

Bone tissue and plasma concentrations of linezolid and vancomycin in rabbits with prosthesis-related infection due to MRSA

Pharmazie 64(6): 407-409

 

Wilms, M.C., S. Stanzel, R.R. Reinert, I. Burckhardt. 2009

Effects of preincubation temperature on the detection of fastidious organisms in delayed-entry samples in the BacT/ALERT 3D blood culture system.

J Micro Meth 79: 194-198

 

Württemberger, M., C. Wendt. 2009

Hygienebeauftragte in der Pflege - ein Konzept für die Praxis.

Hyg Med 34(10): 381-385

 

Zimmermann, S., H. Moll, W. Solbach, C.G.K. Lüder. 2009

Meeting Report IFoLeish-2008: Current Status and Future Challenges in Leishmania Research and Leishmaniasis.

Protist 160: 151-158

Publikationen 2008

Baetz, A., C. Koelsche, J. Strebovsky, K. Heeg, A.H. Dalpke. 2008

Identification of a nuclear localization signal in suppressor of cytokine signaling 1.

FASEB J 22: 4296-4305

  

Bekeredjian-Ding, I., A. Doster, M. Schiller, P. Heyder, H.-M. Lorenz, B. Schraven, U. Bommhardt, K. Heeg. 2008

TLR9-Activating DNA Up-Regulates ZAP70 via Sustained PKB Induction in IgM+ B Cells.

J Immunol 181: 8267-8277

 

Chiron, D., I. Bekeredjian-Ding, C. Pellat-Deceunynck, R. Bataille, G. Jego. 2008

Toll-like receptors: lessons to learn from normal and malignant human B cells.

Blood 112(6): 2205-2213

 

Dalpke, A., K. Heeg, H. Bartz, A. Baetz. 2008

Regulation of innate immunity by suppressor of cytokine signaling (SOCS) proteins.

Immunobiology 213: 225-235

 

Eberle, F., K. Gießler, C. Deck, K. Heeg, M. Peter, C. Richert, A.H. Dalpke. 2008

Modifications in Small Interfering RNA That Separate Immunostimulation from RNA Interference.

Journal of Immunology 180: 3229-3237

 

Fritz, S., W. Hartwig, R. Lehmann, K. Will-Schweiger, M. Kommerell, T. Hackert, L. Schneider, M.W. Büchler, J. Werner. 2008

Prophylactic antibiotic treatment is superior to therapy on-demand in experimental necrotising pancreatitis.

Critical Care 12(6): 195-204

 

Fueller, F., K.F. Kubatzky. 2008

The small GTPase RhoH is an atypical regulator of haematopoietic cells.

Cell Commun Signal 6(1): 6

 

Heeg, K. 2008

The Innate Immune System

In: The Hypothalamus-Pituitary-Adrenal Axis, Neuroimmune Biology, Volume 7

Elsevier ISBN 978-0-444-53040-0

 

Heeg, K., A. Dalpke, M. Peter, S. Zimmermann. 2008

Structural requirements for uptake and recognition of CpG oligonucleotides.

Int J Med Microbiol 298(33): 33-38

 

Hofer, S., C. Eisenbach, I.K. Lukic, L. Schneider, K. Bode, M. Brueckmann, S. Mautner, M.N. Wente, J. Encke, J. Werner, A.H. Dalpke, W. Stremmel, P.P. Nawroth, E. Martin, P.H. Krammer, A. Bierhaus, M.A. Weigand. 2008

Pharmacologic cholinesterase inhibition improves survival in experimental sepsis.

Crit Care Med 36(2): 404-408

  

Jappe, U., D. Heuck, B. Strommenger, C. Wendt, G. Werner, D. Altmann, W. Witte. 2008

Staphylococcus aureus in dermatology outpatients with special emphasis on community-associated methicillin-resistant strains.

J Invest Dematol 128(11): 2655-2664

 

Knorr, B., H. Maul, P. Schnitzler. 2008

Prevalence of hepatitis B virus infection among women at reproductive age at a German university hospital.

Journal of Clinical Virology 42: 422-424

 

Lorenz, H.M., A.H. Dalpke, A. Deboben, A.D. Ho, A. Greiner, M. Jung, C. Fiehn. 2008

Mycobacterium kansasii Tenosynovitis in a Rheumatoid Arthritis Patient With long-Term Therapeutic Immunosuppression.

Arthritis & Rheumatism/Arthritis Care Res 59(6): 900-903

 

Mackensen, F., M.D. Becker, U. Wiehler, R. Max, A. Dalpke, S. Zimmermann. 2008

QuantiFERON TB-Gold - A new test strengthening long suspected tuberculous involvement in serpiginous-like chorioiditis.

Am J Ophthalmol 146(5): 761-766

 

Mayer, A.K., H. Bartz, F. Fey, L.M. Schmidt, A.H. Dalpke. 2008

Airway epithelial cells modify innate and adaptive immune responses by including an anti-inflammatory microenvironment.

Eur J Immunol 38(6): 1689-1699

  

Mrabet-Dahbi, S., A.H. Dalpke, M. Niebuhr, M. Frey, M. Niehbuhr, C. Draing, S. Brand, K. Heeg, T. Werfel, H. Renz. 2008

The heterozygous TLR-2 R753Q mutation in atopic dermatitis: Effect on pro-inflammatory chemokine production, TLR expression and TH1 responses.

J Allergy Clin Immun 121(4): 1013-1019

  

Oberdorfer, K., G. Müssigbrodt, C. Wendt. 2008

Genetic diversity of Legionella pneumophila in hospital water systems.

Int J Hyg Envir Heal 211(1-2): 172-178

 

Parcina, M., C. Wendt, F. Goetz, R. Zawatzky, U. Zähringer, K. Heeg, I. Bekeredjian-Ding. 2008

Staphylococcus aureus-Induced Plasmacytoid Dendritic Cell Activation Is Based on an IgG-Mediated Memory Response.

J Immunol 181 (6): 3823-3833

  

Peter, M., K. Bode, G.B. Lipford, F. Eberle, K. Heeg, A.H. Dalpke. 2008

Characterization of suppressive oligodeoxynucleotides that inhibit Toll-like receptor-9-mediated activation of innate immunity.

Immunology 123: 118-128

 

Piehler, A.P., M. Hellum, J.J. Wenzel, E. Kaminski, K.B.F. Haug, P. Kierolf, W.E. Kaminski, 2008

The human ABC transporter pseudogene family: Evidence fro transcription and gene-pseudogene interference.

BMC Genomics 9: 165-177

 

Rüping, M.J., N. Albermann, F. Ebinger, I. Burckhardt, C. Beisel, C. Müller, J.J. Vehreschild, M. Kochanek, G. Fätkenheuer, C. Bangard, A.J. Ullmann, W. Herr, K. Kolbe, M. Hallek, O.A. Cornely. 2008

Posaconazole concentrations in the central nervous system.

J Antimicrob Chemoth 62: 1468-1470

 

Schiller, M., I. Bekeredjian-Ding, P. Heyder, N. Blank, A.D. Ho, H.M. Lorenz. 2008

Autoantigens are translocated into small apoptotic bodies during early stages of apoptosis.

Cell Death Differ 15: 183.191

 

Swoboda, S., M. Ober, C. Hainer, C. Lichtenstern, C. Seiler, C. Wendt, T. Hoppe-Tichy, M. Büchler, M.A. Weigand. 2008

Tigecycline for the treatment of patients with severe sepsis or septic shock: a drug use evaluation in a surgical intensive care unit.

J Antimicrob Chemoth 61(3): 729-733

 

Theiner, G., S. Rößner, A. Dalpke, K. Bode, T. Berger, A. Gessner, M. Lutz. 2008

TLR9 cooperates with TLR4 to increase IL-12 release by murine dendritic cells

Mol. Immunol.  45: 244-252

 

Zimmermann, S., A. Dalpke, K. Heeg. 2008

CpG oligonucleotides as adjuvant in therapeutic vaccines against parasitic infections.

Int J Med Microbiol 298(1-2): 39-44

 

Publikationen 2007

Baetz, A., S. Zimmermann, A.H. Dalpke. 2007

Microbial immune evasion employing suppressor of cytokine signaling (SOCS) proteins.

Inflammation & Allergy - Drug Targets 6(3): 160-167

 

Bekeredjian-Ding, I., S. Inamura, T. Giese, H. Moll, S. Endres, A. Sing, U. Zähringer, G. Hartmann. 2007

Staphylococcus aureus protein A triggers T cell-independent B cell proliferation by sensitizing B cells for TLR2 ligands.

Journal of Immunology 178: 2803-2812

 

Blümer, N., S. Sel, S. Virna, C.C. Patrascan, S. Zimmermann, U. Herz, H. Renz, H. Garn. 2007

Perinatal maternal application of Lactobacillus rhamnosus GG suppresses allergic airway inflammation in mouse offspring.

Clinical and Experimental Allergy 37: 348-357

 

Bode, K.A., K. Schroder, D.A. Hume, T. Ravasi, K. Heeg, M.J. Sweet, A.H. Dalpke. 2007

Histone deacetylase inhibitors decrease Toll-like receptor-mediated activation of proinflammatory gene expression by impairing transcription factor recruitment.

Immunology 122(4): 596-606

  

Dannewitz, B., S. Pohl, P. Eickholz, T.S. Kim. 2007

Clinical and microbiological effects of a combined mechanic-antibiotic therapy in subjects with Actinobacillus actinomycetemcomitans-associated periodontitis

Am J Dent 20(3): 153-156

 

Hagenah, G.C., T. Wündisch, E. Eckstein, S. Zimmermann, F. Holst, W. Grimm, A. Neubauer, M. Lohoff. 2007

[Sepsis-like disease in an immuncompromised patient with a travel history to Mallorca.]

Internist 48: 727-730 German

  

He, G., A. Patra, K. Siegmund, M. Peter, K. Heeg, A. Dalpke, C. Richert. 2007

Immunostimulatory CpG oligonucleotides form defined three-dimensional structures: Results from an NMR study.

ChemMedChem 2(4): 549-560

 

Heyder, P., I. Bekeredjian-Ding, M. Parcina, N. Blank, A.D. Ho, M. Herrmann, H.-M. Lorenz, K. Heeg, M. Schiller. 2007

Purified apoptotic bodies stimulate plasmacytoid dendritic cells to produceIFN-alpha. Brief Definitive Report

Autoimmunity 40(4): 331-332

 

Järve, A., J. Müller, K. Il-Han, K. Rohr, C. MacLean, G. Fricker, U. Massing, F. Eberle, A. Dalpke, R. Fischer, M.F. Trendelenburg, M. Helm. 2007

Surveillance of siRNA integrity by FRET imaging.

Nucleic Acids Res 35(18): e124

  

Knorr, B., U. Kessler, J. Pöschl, H. Fickenscher, O. Linderkamp. 2007

A haemophagocytic lymphohistiocytosis (HLH)-like picture following breastmilk transmitted cytomegalovirus infection in a preterm infant.

Scand J Infect Dis 39(2): 173-176

 

Mayer, A.K., A.H. Dalpke. 2007

Regulation of local immunity by airway epithelial cells.

Arch Immunol Ther Exp 55: 353-362

  

Mayer, A.K., M. Muehmer, J. Mages, K. Gueinzius, C. Hess, K. Heeg, R. Bals, R. Lang, A.H. Dalpke. 2007

Differential recognition of Toll-like receptor dependant microbial ligands in human bronchial epithelial cells: Implications for pattern recognition at non-sterile mucosal surfaces.

J Immunol 178(5): 3134-3142

 

Nguyen, T.H., T. Hoppe-Tichy, H.K. Geiss, A.C. Rastall, S. Swoboda, J. Schmidt, M.A. Wiegand. 2007

Factors influencing caspofungin plasma concentrations in patients of a surgical intensive care unit.

Journal of Antimicrobial Chemotherapy 60: 100-106

 

Orth, J.H., K. Aktories, K.F. Kubatzky. 2007

Modulation of host cell gene expression through activation of STAT transcription factors by Pasteurella multocida toxin.

J Biol Chem 282(5): 3050-3057

  

Schroder, K., M. Spille, A. Pilz, J. Lattin, K. Bode, K.M. Irvine, A.D. Burrows, T. Ravasi, H. Weighardt, K.J. Stacey, T. Decker, D.A. Hume, A.H. Dalpke, M.J. Sweet. 2007

Differential effects of CpG DNA on IFNb induction and STAT1 activation in murine macrophages versus dendritic cells: identification of a novel function for STAT1 in toll-like receptor signalling.

J Immunol 179(6): 3495-3502

 

Steppan, S., K. Kupfer, A. Mayer, M. Evans, G. Yamasaki, J.M. Greve, M.R. Eckart, D.J. Cassell. 2007

Genome Wide Expression Profiling of Human Peripheral Blood Mononuclear Cells Stimulated With BAY 50-4798, a Novel T Cell Selective Interleukin-2 Analog

J Immunother 30(2): 150-168

 

Swoboda, S., T. Hoppe-Tichy, H.K. Geiss, C. Hainer, T.H. Nguyen, H.P. Knaebel, M.A. Weigand. 2007

[Septic shock to vancomycin-resistant enterococci infection. Tigecycline monotherapy.]

Anaesthesist 56(2): 169-174 German

 

Swoboda, S., M. Ober, K. Anagnostakos, H.K. Geiss, M.A. Wiegand, T. Hoppe-Tichy. 2007

A simple isocratic HPLC assay to determine linezolid concentrations in different biomatrices for in vivo and in vitro studies.

Clin Chem Lab Med 45(8): 1019-1022

 

Tschachler, E., N. Brockmeyer, I. Effendy, H.K. Geiss, S. Harder, M. Hartmann, U. Jappe, A. Plettenberg, H. Rasokat, H. Reimann, P. Shah, M. Stücker, T.A. Wichelhaus, H. Schöfer. 2007

Streptococcal infections of the skin an mucous membranes.

J Dtsch Dermatol Ges 5(6): 527-532

 

Vonberg, R.P., I.F. Chaberny, A. Kola, F. Mattner, S. Borgmann, M. Dettenkofer, D. Jonas, A.M. Fahr, I. Klare, G. Werner, K. Weist, C. Wendt, P. Gastmeier. 2007

[Prevention and control of the spread of vancomycin-resistant enterococci: results of a workshop held by the German Society for Hygiene and Microbiology.]

Anaesthesist 56(2): 151-157

 

Wendt, C., S. Schinke, M. Württemberger, K. Oberdorfer, O. Bock-Hensley, H. von Baum. 2007

Value of whole-body washing with chlorhexidine for the eradication of methicillin-resistant Staphylococcus aureus: a randomized, placebo-controlled, double-blind clinical trial.

Infect Control Hosp Emidemiol 28(9): 1036-1043

 

Wiegand, I., H.K. Geiss, D. Mack, E. Stürenburg, H. Seifert. 2007

Detection of Extended-Spectrum Beta-Lactamase among Enterobacteriaceae by Use of Semiautomated Microbiology Systems and Manual Detection Procedures.

Journal of Clinical Microbiology 45(4): 1167-1174

 

Zimmermann, S., A. Dalpke. 2007

[Molecular biology-based methods for pathogen detection in endophthalmitis.]

Der Ophthalmologe 104(11): 940-946 German

 

Publikationen 2006

Bartz, H., N.M. Avalos, A. Baetz, K. Heeg, A.H. Dalpke. 2006

Involvement of suppressors of cytokine signaling in toll-like receptor-mediated block of dendritic cell differentiation.

Blood 108 (13), 4102-4108 

 

Bekeredjian-Ding, I., S.I. Roth, S. Gilles, T. Giese, A. Ablasser, V. Hornung, S. Endres, G. Hartmann. 2006

T cell-independent TLR-induced IL-12p70 production in primary human monocytes.

J. Immunol. 176: 7438-7446 

 

Bock-Hensley, O., U. Niekusch, M. Klett, C. Wendt. 2006

Zahnhygiene in Altenheimen des Rhein-Neckar-Kreises und der Stadt Heidelberg - Ergebnisse einer Umfrage.

Hyg. Med. 31, 12-15

 

Bosch, K., L. Erdinger, F. Ingel, S. Khussainova, E. Utegenova, Bresgen, N.P.M. Eckl. 2006

Evaluation of the toxicological properties of ground- and surface-water samples from the Aral Sea Basin.

Sci Total Environ 374: 43-50

 

Dalpke, A.H., J. Frank, M. Peter, K. Heeg. 2006

Activation of Toll-Like Receptor 9 by DNA from Different Bacterial Species.

Infect. Immun. 74(2): 940-946

 

del Ray A., V. Renigunta, A.H. Dalpke, J. Leipziger, J.E. Matos, B. Robaye, M. Zuzarte, A. Kavelaars, P.J. Hanley. 2006

Knock-out Mice Reveal the Contribution of P2Y and P2X Receptors to Nucleotide-induced Ca2+ Signaling in Macrophages.

J. Biol. Chem. 281(46): 35147-55

 

Gunale, A., H. von Baum, C. Wendt. 2006

Survival of cephalosporin-resistant enterobacteriaceae on fingers.

Infect Cont Hosp Ep 27, 974-977

 

Harter, C., B. Schulze, H. Goldschmidt, A. Benner, H.K. Geiss, T. Hoppe-Tichy, A.D. Ho, G. Egerer. 2006

Piperacillin/tazobactam vs ceftazidime in the treatment of neutropenic fever in patients with acute leukemia or following autologous peripheral blood stem cell transplantation: a prospective randomized trial.

Bone Marrow Transpl 37, 373-379

 

Keiter, S., A. Rastall, T. Kosmehl, K. Wurm, L. Erdinger, T. Braunbeck, H. Hollert. 2006

Ecotoxicological assessment of sediment, suspended matter and water samples in the upper Danube River - A pilot study in search for the causes for the decline of fish catches.

Environmental Science and Pollution Research 13 (5), 308-319

 

Kola, A., I.F. Chaberny, F. Mattner, U. Reischl, R.P. Vonberg, K. Weist, C. Wendt, W. Witte, S. Ziesing, S. Suerbaum, P. Gastmeier. 2006

Control of methicillin-resistant S. aureus by active surveillance. Results of a workshop held by the Deutsche Gesellschaft für Hygiene und Mikrobiologie.

Anaesthesist 55, 778-783

 

Oberdorfer, K., S. Pohl, M. Frey, K. Heeg, C. Wendt. 2006

Evaluation of a single-locus real-time polymerase chain reaction as a screening test for specific detection of methicillin-resistant Staphylococcus aureus in ICU patients.

Eur J Clin Microbiol Infect Dis. 25, 657-663

 

Petersdorf, S., K. Oberdorfer, C. Wendt. 2006

Longitudinal Study of the Molecular Epidemiology of Methicillin-Resistant Staphylococcus aureus at a University Hospital.

J. Clin. Microbiol. 44 (12), 4297-4302

 

Rastall, A.C., D. Getting, J. Goddard, D.R. Roberts, L. Erdinger. 2006

A biomimetic approach to the detection and identification of estrogen receptor agonists in surface waters using semipermeable membrane devices (SPMDs) and bioassay-directed chemical analysis.

Environmental Science and Pollution Research 13 (4), 256-267

 

Seiler, T.-B., A.C. Rastall, E. Leist, L. Erdinger, T. Braunbeck, H. Hollert. 2006

Membrane Dialysis Extraction (MDE): A Novel Approach for Extracting Toxicologically Relevant Hydrophobic Organic Compounds from Soils and Sediments for Assessment in Biotests.

J. Soils & Sediments 6 (1), 20-29

 

Tietze, K., A. Dalpke, S. Morath, R. Mutters, K. Heeg, C. Nonnenmacher. 2006

Differences in innate immune responses upon stimulation with gram-positive and gram-negative bacteria.

J. Periodontol. Res. 41(5): 447-454 

 

von Baum, H., M. Dettenkofer, A.M. Fahr, P. Heeg, C. Wendt. 2006

Konsensusempfehlungen Baden-Württemberg Umgang mit Patienten mit Glycopeptid-resistenten Enterokokken (GRE)/Vancomycin-resistenten Enterokokken (VRE)

Hyg. Med. 31, 30-32

 

Wendt, C., in Zusammenarbeit mit den Mitgliedern des Netzwerkes Zukunft Hygiene. 2006

Bereitstellung aktueller Informationen zur Infektionsprävention am Beispiel der (aviären) Influenza.

Hyg. Med. 31, 522-525

 

Wendt, C., O. Bock-Hensley, H. von Baum. 2006

Infection control in German nursing homes.

Am J Infect Control. 34, 426-429

 

Wildemann, B., H.K. Geiss, P. Schnitzler. 2006

Erregerdiagnostik.

In: B. Wildemann, P. Oschmann, H. Reiber: Neurologische Labordiagnostik.

Georg Thieme Verlag, Stuttgart, 59-68

 

Zimmermann, S., P.J. Murray, K. Heeg, A.H. Dalpke. 2006

Induction of Suppressor of Cytokine Signaling-1 (SOCS-1) by Toxoplasma gondii Contributes to Immune Evasion in Macrophages by Blocking IFN-g Signaling.

J. Immunol. 176(3): 1840-1847

 

Publikationen 2005

Bartz, H., C. Nonnenmacher, C. Bollmann, M. Kuhl, S. Zimmermann, K. Heeg, R. Mutters. 2005

Micromonas (Peptostreptococcus) micros: unusual case of prosthetic joint infection associated with dental procedures.

Int.J.Med.Microbiol. 294(7): 465-470

 

Brack, W., K. Schirmer, L. Erdinger, H. Hollert. 2005

Effect-directed analysis of mutagens and ethoxyresorufin-o-deethylase inducers in aquatic sediments.

Environ. Toxicol. Chem. 24: 2445-2458

 

Dalpke, A.H., M. Lehner, T. Hartung, K. Heeg. 2005

Differential effects of CpG-DNA in TLR-2/-4/-9 tolerance and cross-tolerance.

Immunology 116: 203-212

 

Erdinger, L., M. Dürr, K.A. Höpker. 2005

Correlations between mutagenic activity of organic extracts of airborne particulate matter, NOx and sulphur dioxide in southern Germany: results of a two-year study.

Environ. Sci. Pollut. Res. Int. 12: 10-20

 

Gabrio, T., S. Broser, L. Erdinger, A. Felder-Kennel, G. Fichtner, E. Haberle, T. Herrmann, H. Kirsch, B. Kouros, B. Link, V. Maisner, V. Mann, O. Papke, I. Piechotowski, E. Rzonca, K.H. Schick, M. Schrimpf, S. Schröder, K. Spoker-Maas, U. Weidner, J. Wuthe, I. Zollner, D. Zoltzer. 2005

Human biomonitoring investigations of organochlorine compounds - PCB, DDE, HCB, beta- and gamma-HCH, PCDD/PCDF, Dioxin-like PCB's and polybrominated biphenyl ethers. (German)

Gesundheitswesen 67: 302-311

 

Geiss, H.K., R. Feldhues, S. Niemann, O. Nolte, R. Rieker. 2005

Landouzy Septicemia (Sepsis Tuberculosa Acutissima) Due to Mycobacterium microti in an Immunocompetent Man

Infection 33(5-6): 393-396

 

Hegele, A., A. Dalpke, K. Heeg, P. Barth, Z. Varga, R. Hofmann, P. Olbert. 2005

Immunostimulatory CpG Oligonucleotides Reduce Tumor Burden after Intravesical Administration in an Orthotopic Murine Bladder Cancer Model.

Tumor Biol. 26: 274-280

 

Hocker, B., C. Wendt, A. Nahimana, B. Tönshoff, P.M. Hauser. 2005

Outbreak of Pneumocystis Pneumonia in Pediatric Renal Transplant Unit.

Emerg. Infect. Dis. 11: 330-332

 

Hollert, H., M. Dürr, R. Holtey-Weber, M. Islinger, W. Brack, H. Farber, L. Erdinger, T. Braunbeck. 2005

Endocrine disruption of water and sediment extracts in a non-radioactive dot blot/RNAse protection-assay using isolated hepatocytes of rainbow trout.

Environ. Sci. Pollut. Res. Int. 12, 347-360

 

Kamimura, M., C. Viedt, A. Dalpke, M.E. Rosenfeld, N. Mackmann, D.M. Cohen, E. Blessing, M. Preusch, C.M. Weber, J. Kreuzer, H.A. Katus, F. Bea. 2005

Interleukin-10 Suppresses Tissue Factor Expression in Lipopolysaccharide-Stimulated Macrophages via Inhibition of Egr-1 and a Serum Response Element/MEK-ERK1/2 Pathway.

Circ. Res. 97(4): 305-313

 

Kaufmann, A., B. Musset, S.H. Limberg, V. Renigunta, R. Sus, A.H. Dalpke, K. Heeg, B. Robaye, P.J. Hanley. 2005

"Host tissue damage" signal ATP promotes non-directional migraton and negatively regulates Toll-like receptor signaling in human monocytes.

J. Biol. Chem. 280(37): 32459-32467

 

Klotz, M., S. Zimmermann, S. Opper, K. Heeg, R. Mutters. 2005

Possible risk for re-colonization with methicillin-resistant Staphylococcus aureus (MRSA) by faecal transmission.

Int. J. Hyg. Environ. Health 208, 401-405 

 

Mrabet-Dahbi, S., K. Breuer, M. Klotz, U. Herz, K. Heeg, T. Werfel, H. Renz. 2005

Deficiency in immunglobulin G2 antibodies against staphylococcal enterotoxin C1 defines a subgroup of patients with atopic dermatitis.

Clin. Exp. Allergy 35: 274-281.

 

Nolte, O., H. Haag, A. Zimmermann, H.K. Geiss. 2005

Staphylococcus aureus positive for Panton-Valentine leukocidin genes but susceptible to methicillin in patients with furuncles.

Eur. J. Clin. Microbiol. Infect. Dis. 24: 477-479

 

Nonnenmacher, C., A.H. Dalpke, J. Rochon, L. Flores-de-Jacoby, R. Mutters, K. Heeg. 2005

Real-Time polymerase chain reaction for detection and quantification of bacteria in periodontal diseased patients.

J. Periodontol. 76(9): 1542-1549

 

Ochs, B.G., M. Kommerell, H.K. Geiss, H.G. Simank. 2005

Improving microbiological diagnostics in septic orthopaedic surgery. Comparative study of patients receiving systemic antibiotic therapy. (German)

Orthopäde 34: 345-351

 

Ostendorf, T., A. Meinhold, C. Harter, H. Salwender, G. Egerer, H.K. Geiss, A.D. Ho. 2005

Chlorhexidine and silver-sulfadiazine coated central venous catheters in haematological patients - a double-blind, randomised, prospective, controlled trial.

Support Care Cancer 13: 993-1000

 

Schöfer, H, N. Brockmeyer, J. Dissemond, I. Effendy, S. Esser, H.K. Geiss, S. Harder, M. Hartmann, U. Jappe, A. Plettenberg, H. Reimann, P. Shah, E. Tschachler, T. Wichelhaus. 2005

Staphylokokken-Infektionen der Haut und Schleimhäute. Leitlinie der Deutschen Dermatologischen Gesellschaft (DDG), Arbeitsgemeinschaft für Dermatologische Infektiologie (ADI)

Chemother J 14: 67-73

 

Swoboda, S., S. Fritz, M.E. Martignoni, R.A. Feldhues, T. Hoppe-Tichy, M.W. Büchler, H.K. Geiss. 2005

Varying linezolid susceptibility of vancomycin-resistant Enterococcus faecium isolates during therapy: a case report.

J Antimicrob Chemother 56: 787-789

 

von Baum, H., J.F. Ober, C. Wendt, R.P. Wenzel, M.B. Edmond. 2005

Antibiotic-Resistant Bloodstream Infections in Hospitalized Patients: Specific Risk Factors in a High-Risk Population?

Infection 33: 320-326

 

Wendt, C., D. Lin, H. von Baum. 2005

Risk Factors for Colonization with Third-Generation Cephalosporin-Resistant Enterobacteriaceae.

Infection 33: 327-332

 

Wendt, C., D. Svoboda, C. Schmidt, O. Bock-Hensley, H. von Baum. 2005

Characteristics that promote transmission of Staphylococcus aureus in german nursing homes.

Infect Cont Hosp Ep 26: 816-821

 

Weseler, A., H.K. Geiss, R. Saller, J. Reichling. 2005

A novel colorimetric broth microdilution method to determine the minimum inhibitory coencentration (MIC) of antibiotics and essential oils against Helicobacter pylori

Pharmazie 60: 498-502

 

Witte, W., C. Braulke, C. Cuny, B. Strommenger, G. Werner, D. Heuck, U. Jappe, C. Wendt, H.J. Linde, D. Harmsen. 2005

Emergence of methicillin-resistant Staphylococcus aureus with Panton-Valentine leukocidin genes in central Europe.

Eur. J. Clin. Microbiol. Infect. Dis. 24: 1-5

 

Publikationen 2004

 

Ahmad-Nejad, P., S. Mrabet-Dahbi, K. Breuer, M. Klotz, T. Werfel, U. Herz, K. Heeg, M. Neumaier, H. Renz. 2004

The toll-like receptor 2 R753Q polymorphism defines a subgroup of patients with atopic dermatitis having severe phenotype.

J.Allergy Clin.Immunol. 113: 565-567

 

Albrecht, I., T. Tapmeier, S. Zimmermann, M. Frey, K. Heeg, A. Dalpke. 2004

Toll-like receptor (TLR) selective nucleosomal remodeling at the IL-12p40 promoter.

EMBO Reports 5: 172-177

 

Arvand, M., R. Feldhues, M. Mieth, T. Kraus, P. Vandamme 2004

Chronic Cholangitis Caused by Bordetella hinzii in a Liver Transplant Recipient.

J.Clin.Microbiol. 42.5: 2335-2337

 

Baetz, A., M. Frey, K. Heeg, A. Dalpke. 2004

Suppressor of cytokine signaling (SOCS) proteins indirectly regulate Toll-like receptor signaling in innate immune cells.

J.Biol.Chem. 279: 54708-54715

 

Bartz, H., Y. Mendoza, M. Gebker, T. Fischborn, K. Heeg, A. Dalpke. 2004

Poly-guanosine strings improve cellular uptake and stimulatory activity of phosphodiester CpG oligonucleotides in human leukocytes.

Vaccine 23: 148-155

 

Beyer, M., H. Bartz, K. Horner, S. Doths, C. Koerner-Rettberg, J. Schwarze. 2004

Sustained increases in numbers of pulmonary dendritic cells after respiratory syncytial virus infection

J Allergy Clin. Immunol. 113: 127-33

 

Dalpke, A., K. Heeg. 2004

CpG DNA as immune response modifier.

Int.J.Med.Microbiol. 294: 345-354

 

Erdinger, L., I. Dörr, M. Dürr, K.A. Höpker. 2004

Analysis of Mutagenic Activity of Airborne Particulate Matter, Standard Reference Materials and Nitrated PAHs using Base Pair-specific Salmonella Typhimurium Tester Strains.

Mutat. Res. 564: 149-157

 

 

Erdinger, L., O. Eckl, F. Ingel, Sh. Khussainova, E. Genova, M. Mann, Th. Gabrio. 2004

The Aral Sea Desaster - Human Biomonitoring of Hg, As, HCB, DDE, and PCBs from Children living in Aralsk and Akchi, Kazakstan.

Int.J.Hyg.Env.Health 207: 541-547

 

Erdinger, L., K. Kühn, R. Feldhues, T. Fröbel, B. Nohynek, Th. Gabrio. 2004

Pathways of THM uptake in swimming pools.

Int.J.Hyg.Env.Health 207: 571-575

 

Ganten, T.M., H.K. Geiss, W. Stremmel. 2004

Infektionen in der Gastroenterologie.

Unimed-Verlag Bremen ISBN 3895997056

 

Geiss, H.K. 2004

Gramnegative Kokken. In: D. Adam, H.W. Doerr, H. Linik, H. Lode.

Die Infektiologie. Springer-Verlag, Heidelberg , 958-961

 

Geiss, H.K. 2004

Meningokokkenerkrankungen. In: R.W. Braun, G.-D. Burchardt, E. Fröhlich, H.D. Nothdurft.

Reise- und Tropenmedizin. Schattauer Verlag Stuttgart, 124-128

 

Geiss, H.K., D. Mack, H. Seifert. 2004

Identifizierung von speziellen Resistenzmechanismen und zur Interpretation von Ergebnissen der Antibiotikaempflichkeitstestung bei grampositiven und grammnegativen Erregern.

Chemother J. 13(1): 1-16

 

Hanley, P. J., B. Musset, V. Renigunta, S. H. Limberg, A. Dalpke, R. Sus, K. Heeg, R. Preisig-Müller, J. Daut. 2004

Extracellular ATP induces oscillations of intracellular Ca2+ and membrane potential and promotes transcription of IL-6 in macrophages.

P.Natl.Acad.Sci.USA 101: 9479-9484

 

Hegele, A., A. Dalpke, P. Barth, Z. Varga, K. Heeg, R. Hofmann, P. Olbert. 2004

Antineoplastic effect of immunostimulatory DNA (CpG-DNA) in a murine C57-BL6/MB-49 transitional cell carcinoma model.

Anticancer Res. 24: 2225-2230

 

Heeg, K., S. Zimmermann, A. Dalpke. 2004

Microbial Adjuvants.

In: Novel Vaccination Strategies.

Kaufmann, S.H.E. (ed.)

Wiley-VCH, Weinheim, pp. 115-128.

 

Hollert, H., B. Braun, S. Mijovic, M., Rakaj, A. Rastall, T.B. Seiler, L. Erdinger. 2004

The EULIMNOS project: strengthening cross-border scientific research and higher education in the Lake Shkodra/Skadar Region.

Environ.Sci.Pollut.Res.Int. 11: 135

 

Jappe, U., D. Petzoldt, C. Wendt. 2004

Methicillin-resistant Staphylococcus aureus Colonization in Inflammatory versus Non-inflammatory Skin Disease: Who should be screened? 2004

Acta Derm.Venereol. 84(3): 181-186

 

Klee, N., L. Gustavsson, Th. Kosmehl, M. Engwall, L. Erdinger, Th. Braunbeck, H. Hollert. 2004

Toxicity and genotoxicity in an industrial sewage sludge containing nitro- and amino-aromatic compounds during treatment in bioreactors under different oxygen regimes.

Environ.Sci.Pollut.Res.Int. 11: 313-320

 

Leaper, D.J., H. van Goor, J. Reilly, N. Petrosillo, H.K. Geiss, A.J. Torres, A. Berger. 2004

Surgical site infection - a European perspective of incidence and economic burden.

Int.Wound J. 1(4): 247-273

 

Nonnenmacher, C., A. Dalpke, R. Mutters, K. Heeg. 2004

Quantitative detection of periodontopathogens by real-time PCR.

J. Microbiol. Meth. 59: 117-125

 

Oberdorfer, K., S. Swoboda, A. Hamann, U. Baertsch, K. Kusterer, B. Born, T. Hoppe-Tichy, H.K. Geiss, H. von Baum. 2004

Tissue and serum levofloxacin concentrations in diabetic foot infection patients.

J.Antimicrob.Chemother. 54(4): 836-839

 

Pawlowski, S., T. Ternes, M. Bonerz, A,. Rastall, L. Erdinger. 2004

Estrogenicity of solid phase-extracted water samples from two municipal sewage treatment plant effluents and river Rhine water using the yeast estrogen screen.

Toxicology in Vitro 18: 129-138

 

Rastall, A., A. Neziri, Z. Vukovic, C. Jung, S. Mijovic, H. Hollert, S. Nikcevic, L. Erdinger. 2004

The identification of readily bioavailable pollutants in Lake Shkodra/Skadar using semipermeable membrane devices (SPMDs), bioassays and chemical analysis.

Environ.Sci.Pollut.Res.Int. 11: 135

 

Ruderich, F., M. Bauch, M. Haag, J. Heid, F.J. Leven, R. Singer, H.K. Geiss, J. Jünger, B. Tönshoff. 2004

Campus - A flexible interactive system for Web-Based, Problem-Based Learing in Health Care. In: Fieschi et al. (Eds.): MEDINFO2004.

IOS Press, Amsterdam, 921-925

 

Schaier, M., C. Wendt, M. Zeier, E. Ritz. 2004

Clostridium difficile diarrhoea in the immunsuppressed patient - update on prevention and management.

Nephrol.Dial.Transplant. 19(10): 2432-2436

 

Schauer, U., S. Hoffjan, T. Rothoeft, H. Bartz, S. König, E. Fuchs, J. Bittscheidt, A. Kochling, V. Stephan. 2004

Severe respiratory syncytial virus infections and reduced interferon-gamma generation in vitro.

Clin. Exp. Immunol. 138(1): 102-109

 

von Baum, H., D. Lin, C. Wendt. 2004

Prevalence of colonisation with third-generation cephalosporin-resistant Enterobacteriaceae in ICU patients of Heidelberg University Hospitals.

Clin.Microbiol.Infect. 10(5): 436-440

 

Wendt, C. 2004

Compliance in der Umsetzung von Hygienerichtlinien.

Bundesgesundheitsbl.Gesundheitsforsch.Gesundheitsschutz 47: 329-333

 

Wendt, C., D. Knautz, H. von Baum. 2004

Differences in Hand Hygiene Behavior Related to the Contamination Risk of Healthcare Activities in Different Groups of Healthcare Workers.

Infect.Control.Hosp.Epidemiol. 25(3): 203-206

 

Wirtz, V.M., J. Kleeff, S. Swoboda, I. Halaceli, H.K. Geiss, T. Hoppe-Tichy, M.W. Büchler, H. Friess. 2004

Moxifloxacin penetration into human gastrointestinal tissues.

J. Antimicrob. Chemother. 53: 875-877

 

Yücel, N., R. Lefering, M. Maegele, M. Max, R. Rossaint, A. Koch, R. Schwarz, M. Korenkov, J. Beuth, A. Bach, J. Schierholz, G. Pulverer, E.A. Neugebauer. 2004

Reduced colonization and infection with miconazole-rifampicin modified central venous catheters: a randomized controlled clinical trial.

J.Antimicrob.Chemother. 54(6): 1109-1115

 

Publikationen 2003

Bock, M., O. Nolte, W. Hartschuh, U. Jappe, H.G. Sonntag. 2003

Lupus vulgaris in a skin graft.

Acta derm. venereol. 83: 132-133

 

Chaberny, I.F., P. Schnitzler, H.K. Geiss, C. Wendt. 2003

An outbreak of epidemic keratoconjunctivitis in a pediatric unit due to adenovirus type 8.

Infect. Cont. Hosp. Ep. 24>:514-519

 

Häfner, B., H. Haag, H.K. Geiss, O. Nolte. 2003

Different molecular methods for the identification of rarely isolated non-tuberculous mycobacteria and description of new hsp65 restriction fragment length polymorphism patterns.

Mol. Cell. Probes 18: 59-65

 

Nolte, O., M. Müller, S. Reitz, S. Ledig, I. Ehrhard, H.G. Sonntag. 2003

Description of new mutations in the rpoB gene in Rifampicin resistant Neisseria meningitidis selected in vitro in a step wise manner.

J. Med. Microbiol. 52: 1077-1081

 

Swoboda, S., K. Oberdorfer, F. Klee, T. Hoppe-Tichy, H. von Baum, H.K. Geiss. 2003

Tissue and serum concentrations of levofloxacin 500 mg administered intravenously or orally for for antibiotic prophylaxis in biliary surgery.

J.Antimicrob.Chemother. 51: 459-462

 

Wagner, J., M. Jabbusch, M. Eisenblätter, H. Hahn, C. Wendt, R. Ignatius. 2003

Susceptibilities of Campylobacter jejuni isolates from Germany to ciprofloxacin, moxifloxacin, erythromycin, clindamycin and tetracycline.

Antimicrob. Agents Ch. 47: 2358-2361