Kliniken &… Institute Zentrum für… Medizinische… Diagnostik / Forschung… Forschung Diagnostic… Burckhardt

Burckhardt lab

apl. Prof. Dr. med. Irene Burckhardt

Department for Infectious Diseases
Medical Microbiology and Hygiene
Im Neuenheimer Feld 324
69120 Heidelberg

Phone +49 6221 56 37795
Fax +49 6221 56 4343


S. pneumoniae: identification, pathogenicity factors, serotype distribution, susceptibility testing
MALDI-TOF: susceptibility testing, detection of carbapenemases, typing
Diagnostic microbiology: sensitivity, detection limits, automation (TLA: total lab automation)

Evaluation of EUCAST rapid antimicrobial susceptibility testing (RAST) for positive blood cultures in clinical practice using a total lab automation.
Jasuja JK, Zimmermann S, Burckhardt I. 2020
Eur J Clin Microbiol Infect Dis (2020). doi: 10.1007/s10096-020-03846-3

Laborautomation in der Mikrobiologie - Zu einer schnelleren und besserenindividualisierten Diagnostik
Burckhardt I. 2019
Biospektrum (2019) 25: 620. DOI: 10.1007/s12268-019-0204-1

Laborautomatisierung in der Mikrobiologie
Burckhardt I.
https://www.labo.de/labordiagnostik/laborautomatisierung-in-der-mikrobiologie.htm 21.08.2019, 10:00

In vitro activity of newer antimicrobials against penicillin non-susceptible strains of Streptococcus pneumoniae.
Hipp M, Burckhardt I.
Infect Drug Resist. 2019 Jul 1;12:1889-1893. doi: 10.2147/IDR.S202789. eCollection 2019

Analysis of Streptococcus pneumoniae using Fourier-transformed infrared spectroscopy allows prediction of capsular serotype.
Burckhardt I, Sebastian K, Mauder N, Kostrzewa M, Burckhardt F, Zimmermann S.
Eur J Clin Microbiol Infect Dis. 2019 Jul 9. doi: 10.1007/s10096-019-03622-y. [Epub ahead of print]

Laboratory Automation in Clinical Microbiology.
Burckhardt I.
Bioengineering (Basel). 2018 Nov 22;5(4). pii: E102. doi: 10.3390/bioengineering5040102.

Shorter Incubation Times for Detecting Multi-drug Resistant Bacteria in Patient Samples: Defining Early Imaging Time Points Using Growth Kinetics and Total Laboratory Automation.
Burckhardt I, Last K, Zimmermann S.
Ann Lab Med. 2019 Jan;39(1):43-49. doi: 10.3343/alm.2019.39.1.43.

Susceptibility Testing of Bacteria Using Maldi-Tof Mass Spectrometry.
Burckhardt I, Zimmermann S.
Front Microbiol. 2018 Aug 6;9:1744. doi: 10.3389/fmicb.2018.01744. eCollection 2018.

Detection of MRSA in nasal swabs-marked reduction of time to report for negative reports by substituting classical manual workflow with total lab automation.
Burckhardt I, Horner S, Burckhardt F, Zimmermann S.
Eur J Clin Microbiol Infect Dis. 2018 Sep;37(9):1745-1751. doi: 10.1007/s10096-018-3308-5. Epub 2018 Jun 25.

Significant increase in cultivation of Gardnerella vaginalis, Alloscardovia omnicolens, Actinotignum schaalii, and Actinomyces spp. in urine samples with total laboratory automation.
Klein S, Nurjadi D, Horner S, Heeg K, Zimmermann S, Burckhardt I.
Eur J Clin Microbiol Infect Dis. 2018 Apr 13. doi: 10.1007/s10096-018-3250-6. [Epub ahead of print]

Identification of Streptococcus pneumoniae: Development of a Standardized Protocol for Optochin Susceptibility Testing Using Total Lab Automation
Burckhardt I, Panitz J, Burckhardt F, Zimmermann S.
BioMed Research International; Volume 2017 (2017), Article ID 4174168, 7 pages. doi: 10.1155/2017/4174168  

Streptococcus pneumoniae as an agent of urinary tract infections – a laboratory experience from 2010 to 2014 and further characterization of strains
Burckhardt I, Panitz J, van der Linden M, Zimmermann S.
Diagn Microbil Infect Dis; 86(2016)97-101. doi: 10.1016/j.diagmicrobio.2016.06.009  

Serotyping of pneumococci: evaluation of the genetic approach and performance with clinical samples.
Burckhardt I, Roemer J, Burckhardt F, Zimmermann S.
Diagn Microbiol Infect Dis. 2014 Dec;80(4):274-7. doi: 10.1016/j.diagmicrobio.2014.08.013. Epub 2014 Sep 2

Using matrix-assisted laser desorption ionization-time of flight mass spectrometry to detect carbapenem resistance within 1 to 2.5 hours.
Burckhardt I, Zimmermann S.
J Clin Microbiol. 2011 Sep;49(9):3321-4. doi: 10.1128/JCM.00287-11. Epub 2011 Jul 27

Streptococcus pneumoniae in urinary tracts of children with chronic kidney disease.
Burckhardt I, Zimmermann S.
Emerg Infect Dis. 2011 Jan;17(1):120-2. doi: 10.3201/eid1701.100895

Risk factor analysis for pneumococcal meningitis in adults with invasive pneumococcal infection.
Burckhardt I, Burckhardt F, VAN DER Linden M, Heeg C, Reinert RR.
Epidemiol Infect. 2010 Sep;138(9):1353-8. doi: 10.1017/S0950268809991683. Epub 2010 Jan 22

Effects of preincubation temperature on the detection of fastidious organisms in delayed-entry samples in the BacT/ALERT 3D blood culture system.
Wilms MC, Stanzel S, Reinert RR, Burckhardt I.
J Microbiol Methods. 2009 Nov;79(2):194-8. doi: 10.1016/j.mimet.2009.08.015. Epub 2009 Sep 4.