Kliniken &… Kliniken Zentrum für Kinder- und… IV - Neonatologie





Frommhold D, Kamphues A, Buschmann K, Lange-Sperandio B, Nawroth P, Bierhaus A, Poeschl J and Sperandio M: RAGE differentially controls leukocyte recruitment during acute inflammation in a stimulus-dependent manner. BMC Immunol, 12:56, 2011. (IF3,0)


Frommhold D, Tschada J, Buschmann K, Doerner A, Stahl M, Wang H, Koch L, Sperandio M, Isermann B and Poeschl: Protein C concentrate controls leukocyte recruitment during inflammation and improves survival during endotoxemia after efficient in vivo activation. Am J Pathology, 175:2637-50,2011. (IF 6)


Koch L, Dabek MT, Frommhold D, Poeschl J: Stable precursor fragments of vasoactive peptides in umbilical cord blood of term and preterm infants. Horm Res Paediatr, 76:234-9, 2011. (IF 2,0)




Koch L, Frommhold D, Beedgen B, Ruef P, Poeschl J: Prophylactic administration of surfactant in extremely premature infants. Crit Care Res Pract pii: 235894. Epub 2010 Jun 7 2010.


Koch L, Fritzsching B, Frommhold D, Poeschl J: Lipopolysaccharide-Induced Expression of Th1/Th2 Cytokines in Whole Neonatal Cord and Adult Blood: Role of Nuclear Factor-Kappa B and p38 MAPK. Neonatology 99:140-145, 2010. (IF 2,0)


Frommhold D, Kamphues A, Hepper I, Pruenster M, Lukic IK, Socher I, Zablotskaya V, Buschmann K, Lange-Sperandio B, Schymeinsky J, Ryschich E, Poeschl J, Kupatt C, Nawroth PP, Moser M, Walzog B, Bierhaus A, Sperandio M: RAGE and ICAM-1 cooperate in mediating leukocyte recruitment during acute inflammation in vivo. Blood 116:841-9, 2010.  (IF 10,4)



Ruef P, Craciun E, Altfelder F, Simon C, Frommhold D, Koch L, Pöschl J: Effects of phosphodiesterase (III/IV)-inhibitors and cytokines on mechanical properties of neutrophilic granulocytes in neonates and adults. Clin Hemorheol Microcirc 45:301-10, 2010. (IF1,8)




Schymeinsky J, Gerstl R, Mannigel I, Niedung K, Frommhold D, Panthel K, Heesemann J, Sixt M, Quast T, Kolanus W, Mocsai A, Wienands J, Sperandio M, Walzog B. A fundamental role of mAbp1 in neutrophils: impact on beta(2) integrin-mediated phagocytosis and adhesion in vivo. Blood 114:4209-20, 2009. (IF 10,4)


Seehaus S, Shahzad K, Kashif M, Vinnikov IA, Schiller M, Wang H, Madhusudhan T, Eckstein V, Bierhaus A, Bea F, Blessing E, Weiler H, Frommhold D, Nawroth PP, Isermann B: Hypercoagulability inhibits monocyte transendothelial migration through protease-activated receptor-1-, phospholipase-Cbeta-, phosphoinositide 3-kinase-, and nitric oxide-dependent signaling in monocytes and promotes plaque stability. Circulation 120:774-84, 2009. (IF14,8)


Jakus Z, Simon E, Frommhold D, Sperandio M, Mócsai A: Critical role of phospholipase Cgamma2 in integrin and Fc receptor-mediated neutrophil functions and the effector phase of autoimmune arthritis. J Exp Med 206:577-93, 2009. (IF 14,5)


Koch L, Hofer S, Weigand MA, Frommhold D, Poeschl J: Lipopolysaccharide-induced activation of coagulation in neonatal cord and adult blood monitored by thrombelastography. Thromb Res  124:463-7, 2009. (IF 2,4)




Frommhold D*, Ludwig A*, Bixel G, Zarbock A, Babushkina I, Weissinger M, Cauwenberghs S, Lange-Sperandio B, Ellies L, Marth JD, Beck-Sickinger AG, Zernecke A, Vestweber D, Weber C, Ley K and Sperandio M: Sialyltransferase ST3Gal-IV controls CXCR2 mediated firm leukocyte arrest during inflammation. J Exp Med 205: 1435-46, 2008. (IF 14,5)


Yakubenia S*, Frommhold D*, Schölch D, Hellbusch CC, Körner C, Petri B, Jones C, Ipe U, Bixel MG, Krempien R, Sperandio M and Wild M: Leukocyte trafficking in a mouse model for Leukocyte Adhesion deficiencyII/Congenital Disorder of Glycosylation IIc. Blood 112:1472-81, 2008. (IF 10,4)


Beckermann BM*, Kallifatidis G*, Groth A, Frommhold D, Apel A, Mattern J, Salnikov AV, Moldenhauer G, Wagner W, Diehlmann A, Saffrich R,  Schubert M, Ho AD, Giese N, Büchler MW, Friess H, Büchler P and Herr I:VEGF expression by mesenchymal stem cells contributes to angiogenesis of pancreatic carcinoma. Br J Cancer 99:622-31, 2008. (4,5)



Frommhold D, Mannigel I, Schymeinsky J, Mocsai A, Walzog B and Sperandio M: Syk is critical for sustained leukocyte adhesion during inflammation in vivo. BMC Immunol 28;8:31, 2007. (IF 3,1)


Hellbusch CC, Sperandio M, Frommhold D, Yakubenia S, Wild MK, Popovici D, Vestweber D, Grone HJ, von Figura K, Lubke T, Korner C: Golgi GDP-fucose transporter-deficient mice mimic congenital disorder of glycosylation IIc/Leukocyte adhesion deficiency II. J Biol Chem 282:10762-72, 2007. (IF 5,8)




Sperandio M, Frommhold D, Babushkina I, Ellies LG, Olson TS, Smith ML, Fritzsching B, Pauly E, Smith DF, Nobiling R, Linderkamp O, Marth JD, Ley K: ST3Gal-IV is essential for L-selectin ligand function in inflammation. Eur J Immunol 36:3207-3215, 2006. (IF 4,8)


Schymeinsky J, Sindrilaru A, Frommhold D, Sperandio M, Gerstl R, Then C, Mocsai A, Scharffetter-Kochanek K, Walzog B: The Vav binding site of the non-receptor tyrosine kinase Syk at Tyr 348 is critical for ß2 integrin (CD11/CD18)-mediated neutrophil migration. Blood  108:3919-27, 2006. (IF 10,5)


2005 und früher


Frommhold D, Zilow E P, Birle A, Linderkamp O, Poeschl J: Activated protein C (Drotrecogin alpha) in neonatal septic shock. Scand J Inf Dis 37: 306-308, 2005. (IF 1,6)


Schulze A, Frommhold D, Hoffmann GF, and Mayatepek, E: Spectrophotometric microassay for delta-aminolevulinate dehydratase in dried blood spots as confirmation test for hereditary tyrosinemia type I, Clin Chem 47:1424-1429, 2001.  (IF 5,5)            


Schulze A, Frommhold D, Mayatepek E and Hoffmann GF: A new approach in neonatal screening for hereditary tyrosinemia type <st1:place w:st="on">I.</st1:place> J Inherit Metab Dis 23, Suppl 1: 7, 2000. (IF 1,6)


Schulze A, Schmidt H, Frommhold D and  Mayatepek E: The early course of phenylalanine and phenylalanine-tyrosine ratio in a PKU newborn. J Inherit Metab Dis 22, Suppl 1: 125, 1999. (IF 1,6)


Frommhold D, Kramer A und Seipelt H: Giftschlangenbisse und ihre Behandlung. Hyg Med 23: 559, 1998.