Kliniken &… Institute Abteilung… Abteilung… Forschung Publikationen

Chronische Krankheiten und Multimorbidität

* Die fett hervorgehobenen Autoren sind Mitarbeiter der Abteilung Allgemeinmedizin und Versorgungsforschung.


Nisius K, Hoffmann D, Görig T, Georg S, Krug K, De Bock F, Eichinger M. Perceived shared decision making and satisfaction with care among children and adolescents with special healthcare needs and their parents: Cross-sectional evidence from the PART-CHILD Study. Patient Educ Couns. 2024 Jan 26;123:108175. doi: 10.1016/j.pec.2024.108175. Epub ahead of print. 
→ Links: PMID: 38492427; ScienceDirect.

Poß-Doering R, Keller S, Zugaj M, Seidling H, Paul C, Stolz R, Kaufmann-Kolle P, Straßner C. Hausärztliche Versorgung von Patient:innen mit chronischen nicht-tumorbedingten Schmerzen: ein Rapid Review im Rahmen des RELIEF-Projekts [General practice care for patients with chronic non-cancer pain: A rapid review as part of the RELIEF project]. Z Evid Fortbild Qual Gesundhwes. 2024 Mar 11:S1865-9217(24)00011-4. German. doi: 10.1016/j.zefq.2024.01.005. Epub ahead of print. 
→ Links: PMID: 38472021; ScienceDirect.


Arnold C, Hennrich P, Peters-Klimm F, Wensing M. Influence of Cooperation Work on Management Continuity of Ambulatory Cardiovascular Care: A Cross-Sectional Exploratory Study in Germany. Int J Integr Care. 2023 Dec 6;23(4):14. doi: 10.5334/ijic.7019. 
→ Links: PMID: 38074514; PMCID: PMC10705028; IJIC.

Daniel T, Spingler T, Hug A, Weidner N, Wensing M, Ullrich C. Current practice of outpatient rehabilitation services in patients with mobility-impaired paralysis due to stroke or spinal cord injury: a qualitative interview study in Germany. Disabil Rehabil. 2023 Sep 21:1-14. doi: 10.1080/09638288.2023.2259301. Epub ahead of print.
→ Links: PMID: 37732606; Taylor & Francis Online.

Klafke N, Bossert J, Kröger B, Neuberger P, Heyder U, Layer M, Winkler M, Idler C, Kaschdailewitsch E, Heine R, John H, Zielke T, Schmeling B, Joy S, Mertens I, Babadag-Savas B, Kohler S, Mahler C, Witt CM, Steinmann D, Voiss P, Stolz R. Prevention and Treatment of Chemotherapy-Induced Peripheral Neuropathy (CIPN) with Non-Pharmacological Interventions: Clinical Recommendations from a Systematic Scoping Review and an Expert Consensus Process. Med. Sci. 2023; 11(1):15. doi: 10.3390/medsci11010015.
→ Links: MDPI.

Senft JD, Fleischhauer T, Poß-Doering R, Frasch J, Feißt M, Awounvo S, Müller-Bühl U, Altiner A, Szecsenyi J, Laux G. Primary Care Disease Management for Venous Leg Ulceration in German Healthcare: Results of the Ulcus Cruris Care Pilot Study. Healthcare 2023;11(18):2521. doi: 10.3390/healthcare11182521.
→ Links: MDPI.

Straßner C, Mächler R, Sturm N, Valentini J, Stolz R, Joos S, Frick E. Die spirituelle Anamnese aus ärztlicher und patientenseitiger Sicht – eine Gegenüberstellung im Rahmen des Projekts HoPES3. Spiritual Care. 2023;12(3): 202-210. doi: 10.1515/spircare-2023-0025.
→ Links: De Gruyter.


Arnold C, Hennrich P, Wensing M. Information exchange networks for chronic diseases in primary care practices in Germany: a cross-sectional study. BMC Prim Care 2022; 23(56). doi: 10.1186/s12875-022-01649-3
→ Links: PMID: 35346050; PMCID: PMC8958478BMC; pdf-Dokument.

Arnold C, Hennrich P, Wensing M. Patient-reported continuity of care and the association with patient experience of cardiovascular prevention: an observational study in Germany. BMC Prim Care. 2022 Jul 18;23(1):176. doi: 10.1186/s12875-022-01788-7.
→ Links: PMID: 35850657; PMCID: PMC9289649; BMC; pdf-Dokument.

Bossert J, Vey JA, Piskorski L, Fleischhauer T, Awounvo S, Szecsenyi J, Senft J. Effect of educational interventions on wound healing in patients with venous leg ulceration: A systematic review and meta-analysis. Int Wound J. 2022 Nov 21. doi: 10.1111/iwj.14021. Epub ahead of print.
→ Links: PMID: 36408782; Wiley Online Library.

Breckner A, Litke N, Göbl L, Wiezorreck L, Miksch A, Szecsenyi J, Wensing M, Weis A. Effects and Processes of an mHealth Intervention for the Management of Chronic Diseases: Prospective Observational Study. JMIR Form Res. 2022 Aug 25;6(8):e34786. doi: 10.2196/34786.
→ Links: PMID: 36006666; JMIR; pdf-Dokument.

Huperz C, Sturm N, Frick E, Mächler R, Stolz R, Schalhorn F, Valentini J, Joos S, Straßner C. Experiences of German health care professionals with spiritual history taking in primary care: a mixed-methods process evaluation of the HoPES3 intervention. Fam Pract. 2022 Oct 15:cmac106. doi: 10.1093/fampra/cmac106. Epub ahead of print.
→ Links: PMID: 36242538; ResearchGate; pdf-Dokument.

Mächler R, Sturm N, Frick E, Schalhorn F, Stolz R, Valentini J, Krisam J, Straßner C. Evaluation of a Spiritual History with Elderly Multi-Morbid Patients in General Practice-A Mixed-Methods Study within the Project HoPES3. Int J Environ Res Public Health. 2022 Jan 4;19(1):538. doi: 10.3390/ijerph19010538. 
→ Links: PMID: 35010797; PMCID: PMC8744880; pdf-Dokument.

Schwill S, Krug K, Poppleton A, Reith D, Senft JD, Szecsenyi J, Stengel S. How can competencies in minor surgery in general practice be increased? Assessing the effect of a compact intervention in postgraduate training: a mixed-methods study. BMJ Open. 2022 Jul 28;12(7):e060991. doi: 10.1136/bmjopen-2022-060991.
→ Links: PMID: 35902194; BMJ Open; pdf-Dokument.

Senft JD, Brück BB, Poß-Doering R, Bruckner T, Szecsenyi J, Müller-Stich BP, Laux G. Need for nursing care after laparoscopic and open colorectal cancer surgery: a claims data analysis in German primary care. Langenbecks Arch Surg. 2022 Jun 27. doi: 10.1007/s00423-022-02592-8. Epub ahead of print.
→ Links: PMID: 35761148; Springer Link; pdf-Dokument.

Senft JD, Fleischhauer T, Frasch J, van Rees W, Feißt M, Schwill S, Fink C, Poß-Doering R, Wensing M, Müller-Bühl U, Szecsenyi J. Primary care disease management for venous leg ulceration-study protocol for the Ulcus Cruris Care [UCC] randomized controlled trial (DRKS00026126). Trials. 2022 Jan 20;23(1):60. doi: 10.1186/s13063-021-05944-9.
→ Links: PMID: 35057840; PMCID: PMC8771170; pdf-Dokument.


Arnold C, Koetsenruijter J, Forstner J, Peters-Klimm F, Wensing M. Influence of physician networks on prescribing a new ingredient combination in heart failure: a longitudinal claim data-based study. Implement Sci. 2021 Aug 28;16(1):84. doi: 10.1186/s13012-021-01150-y.
→ Links: PMID: 34454547; BMC; pdf-Dokument.

Breckner A, Roth C, Glassen K, Wensing M. Self-management perspectives of elderly patients with multimorbidity and practitioners - status, challenges and further support needed? BMC Fam Pract. 2021 Nov 26;22(1):238. doi: 10.1186/s12875-021-01584-9. 
→ Links: PMID: 34836506; PMCID: PMC8624621; pdf-Dokument.

Eckert T, Wronski P, Bongartz M, Ullrich P, Abel B, Kiss R, Wensing M, Koetsenruijter J, Hauer K. Cost-Effectiveness and Cost-Utility of a Home-Based Exercise Program in Geriatric Patients with Cognitive Impairment. Gerontology. 2021 Jan 27:1-13. doi: 10.1159/000512748. Epub ahead of print.
→ Links: PMID: 33503629.

Janka SS, Bätzing J, Laux G, Holstiege J, Wahler S, Merle U, Mehrabi A, Mohr I, Weiss KH, Mieth M. Retrospective cross-sectional study based on nationwide data of drug prescriptions and contractional data of outpatient offices regarding Morbus Wilson's disease. Z Gastroenterol 2020;58(11):1054-1064. doi: 10.1055/a-1246-3190.
→ Links: PMID: 33197948; pdf-Dokument.

Müller-Tasch T, Krug K, Peters-Klimm F. Associations between NT-proBNP and psychosocial factors in patients with chronic systolic heart failure. J Psychosom Res. 2021 Feb 2;143:110385. doi: 10.1016/j.jpsychores.2021.110385. Epub ahead of print.
→ Links: PMID: 33601116; pdf-Dokument.

Senft JD, Freund T, Wensing M, Schwill S, Poß-Doering R, Szecsenyi J, Laux G. Primary care practice-based care management for chronically ill patients (PraCMan) in German healthcare: Outcome of a propensity-score matched cohort study. Eur J Gen Pract. 2021 Dec;27(1):228-234. doi: 10.1080/13814788.2021.1962280.
→ Links: PMID: 34378482; PMCID: PMC8366669; pdf-Dokument.

Steinmann D, Babadağ Savaş B, Felber S, Joy S, Mertens I, Cramer H, Paul A, Layer M, Klafke N, Stolz R, Heyder U, Neuberger P, Winkler M, Idler C, Heine R, Kaschdailewitsch E, John H, Schmeling B, Zielke T, Horneber M, Witt CM, Voiss P. Nursing Procedures for the Prevention and Treatment of Mucositis Induced by Cancer Therapies: Clinical Practice Guideline Based on an Interdisciplinary Consensus Process and a Systematic Literature Search. Integr Cancer Ther. 2021 Jan-Dec;20:1534735420940412. doi: 10.1177/1534735420940412.
→ Links: PMID: 33467951; PMCID: PMC7960907; pdf-Dokument.

Sturm N, Stolz R, Schalhorn F, Valentini J, Krisam J, Frick E, Mächler R, Szecsenyi J, Straßner C. Self-Efficacy, Social Activity, and Spirituality in the Care of Elderly Patients with Polypharmacy in Germany-A Multicentric Cross-Sectional Study within the HoPES3 Trial. Healthcare (Basel). 2021 Oct 1;9(10):1312. doi: 10.3390/healthcare9101312. 
→ Links: PMID: 34682993; PMCID: PMC8544376.


Arnold C, Hennrich P, Koetsenruijter J, Lieshout JV, Peters-Klimm F, Wensing M. Cooperation networks of ambulatory health care providers: exploration of mechanisms that influence coordination and uptake of recommended cardiovascular care (ExKoCare): a mixed-methods study protocol. BMC Fam Pract 2020; 21(168). doi: 10.1186/s12875-020-01229-3 (Link)

Eckert T, Wronski P, Bongartz M, Ullrich P, Abel B, Kiss R, Wensing M, Koetsenruijter J, Hauer K. Cost-Effectiveness and Cost-Utility of a Home-Based Exercise Program in Geriatric Patients with Cognitive Impairment. Gerontology. 2021 Jan 27:1-13. doi: 10.1159/000512748. Epub ahead of print.
→ Links: PMID: 33503629.

Müller G, Lyssenko L, Giurgiu M, Pfinder M, Clement M, Kaiserauer A, Heinzel-Gutenbrunner M, Kohlmann T, BöS K. How effective and efficient are different exercise patterns in reducing back pain? Eur J Phys Rehabil Med. 2020 Jun 4. doi: 10.23736/S1973-9087.20.05975-4. Epub ahead of print. (PMID: 32498492).

Müller-Bühl K, Senft J, Szecsenyi J, Laux G. Long-term Physical Exercise in Patients with Intermittent Claudication. Angiol Open Access 2020;8:236. doi: 10.35248/2329-9495.20.8.236. (Link)

Weis A, Pohlmann S, Poss-Doering R, Strauss B, Ullrich C, Hofmann H, Ose D, Winkler EC, Szecsenyi J, Wensing M. Caregivers' role in using a personal electronic health record: a qualitative study of cancer patients and caregivers in Germany. BMC Med Inform Decis Mak 2020 Jul 13;20(1):158. doi: 10.1186/s12911-020-01172-4. (Link) (pdf-Dokument)


Kamradt M, Ose D, Krisam J, Jacke C, Salize H-J, Besier W, Mayer M, Szecsenyi JWensing M. Meeting the needs of multimorbid patients with Type 2 diabetes mellitus - A randomized controlled trial to assess the impact of a care management intervention aiming to improve self-care. Diabetes Res Clin Pract 2019;150:184-193. doi: 10.1016/j.diabres.2019.03.008. (Link)

Karstens S, Krug K, Raspe H, Wunderlich M, Hochheim M, Joos S, Hüppe A. Prognostic ability of the German version of the STarT Back tool: analysis of 12-month follow-up data from a randomized controlled Trial. BMC Musculoskelet Disord 2019;20(1):94. doi: 10.1186/s12891-019-2467-6. (Link)

Ose D, Kamradt MKiel MFreund T, Besier W, Mayer M, Krisam J, Wensing M, Salize HJ, Szecsenyi J. Care management intervention to strengthen self-care of multimorbid patients with type 2 diabetes in a German primary care network: A randomized controlled Trial. PLoS One 2019;14(6):e0214056. doi: 10.1371/journal.pone.0214056. (Link)

Schmidt C, Heidemann C, Rommel A, Brinks R, Claessen H, Dreß J, Hagen B, Hoyer A, Laux G, Pollmanns J, Präger M, Böhm J, Drösler S, Icks A, Kümmel S, Kurz C, Kvitkina T, Laxy M, Maier W, Narres M, Szecsenyi J, Tönnies T, Weyermann M, Paprott R, Reitzle L, Baumert J, Patelakis E, Ziese T. Sekundärdaten in der Diabetes-Surveillance – Kooperationsprojekte und Referenzdefinition zur dokumentierten Diabetesprävalenz. Journal of Health Monitoring 2019;4(2):54-68. doi: 10.25646/5982. (PDF-Dokument)

Senft JDWensing MPoss-Doering RSzecsenyi JLaux G. Effect of involving certified healthcare assistants in primary care in Germany: a cross-sectional study. BMJ Open 2019;9:e033325. doi: 10.1136/bmjopen-2019-033325. (Link)



Leutgeb R, Berger S, Szecsenyi J, Laux G. Patients with somatoform disorders: More frequent attendance and higher utilization in primary Out-of-Hours care? PLoS One 2018;13:e0202546. doi: 10.1371/journal.pone.0202546. (Link)

Schwill SKrug KPeters-Klimm F, van Lieshout J, Laux GSzecsenyi JWensing M. Novel oral anticoagulants in primary care in patients with atrial fibrillation: a cross-sectional comparison before and after their introduction. BMC Fam Pract 2018;191:115. doi: 10.1186/s12875-018-0796-4. (Link)  

Zeugfang D, Wisetborisut A, Angkurawaranon C, Aramrattana A, Wensing MSzecsenyi JKrug K. Translation and validation of the PACIC+ questionnaire: the Thai version. BMC Fam Pract 2018;19:123. doi: 10.1186/s12875-018-0801-y. (Link)



Gustafsson PE, Bozorgmehr K, Hammarström A, Sebastian MS. What role does adolescent neighborhood play for adult health? A cross-classified multilevel analysis of life course models in Northern Sweden. Health Place. 2017; 46: 137-144 - doi: 10.1016/j.healthplace.2017.04.013 (Link

Jäger C, Steinhäuser J, Freund T, Kuse S, Szecsenyi J, Wensing M. A tailored programme to implement recommendations for multimorbid patients with polypharmacy in primary care practices-process evaluation of a cluster randomized trial. Implement Sci 2017 ; 12: 31 - doi: 10.1186/s13012-017-0559-y (PDF-Dokument)

Laux G. Hausarztzentrierte Versorgung. In: Pundt, J. (Hrsg.) Michell-Auli, P. (Hrsg.) Vernetzte Versorgung - Lösung für Qualitäts- und Effizienzprobleme in der Gesundheitswirtschaft, Bremen: Apollon University Press, 2017 (in press)

Kamradt M, Krisam J, Kiel M, Qreini M, Besier W, Szecsenyi J, Ose D. Health-Related Quality of Life in Primary Care: Which Aspects Matter in Multimorbid Patients with Type 2 Diabetes Mellitus in a Community Setting? PLoS ONE 2017; 12: e0170883 - doi:10.1371/journal. pone.0170883 (PDF-Dokument)

Straßner C, Steinhäuser J, Freund T, Szecsenyi J, Wensing M. German healthcare professionals' perspective on implementing recommendations about polypharmacy in general practice: a qualitative study. Fam Pract. 2017 Dec 16 - doi: 10.1093/fampra/cmx127 (Link)

Wensing M, Szecsenyi J, Stock C; Kaufmann-Kolle P; Laux G. Evaluation of a program to strengthen general practice care for patients with chronic disease in Germany. BMC Health Serv Res 2017 (in press)



Baudendistel I, Winkler E, Kamradt M, Brophy S, Längst G, Eckrich F, Heinze O, Bergh B, Szecsenyi J, Ose D. Cross-sectoral cancer care: views from patients and health care professionals regarding a personal electronic health record. Eur. J. Cancer Care 2016 (article first published online) - doi: 10.1111/ecc.12429 (Abstract)

Huntink E, Wensing M, Timmers IM, van Lieshout J. Process evaluation of a tailored intervention programme of cardiovascular risk management in general practices. Implement Sci. 2016; 11:164 - doi: 10.1186/s13012-016-0526-z (PDF-Dokument)

Jäger C, Steinhäuser J, Freund T, Baker R, Agarwal S, Godycki-Cwirko M, Kowalczyk A, Aakhus E, Granlund I, van Lieshout J, Szecsenyi J, Wensing M. Process evaluation of five tailored programs to improve the implementation of evidence-based recommendations for chronic conditions in primary care. Implement Sci 2016; 11: 123 - doi: 10.1186/s13012-016-0473-8 (PDF-Dokument)

Laux G, Berger S, Szecsenyi J, Kaufmann-Kolle P, Leutgeb R. Prescribing differences in family practice for diabetic patients in Germany according to statutory or private health insurance: the case of DPP-4-inhibitors and GLP-1-agonists. BMC Family Practice 2016 (in press)

van Lieshout J, Huntink E, Koetsenruijter J, Wensing M. Tailored implementation of cardiovascular risk management in general practice: a Cluster randomized trial. Implement Sci. 2016;11: 115 - doi: 10.1186/s13012-016-0460-0 (PDF-Dokument)

Schmidt K, Worrack S, Von Korff M, Davydow D, Brunkhorst F, Ehlert U, Pausch C, Mehlhorn J, Schneider N, Scherag A, Freytag A, Reinhart K, Wensing M, Gensichen J; SMOOTH Study Group. Effect of a Primary Care Management Intervention on MentalHealth–Related Quality of Life Among Survivors of Sepsis. A Randomized Clinical Trial. JAMA 2016 ; 315(24): 2703-2711 - doi: 10.1001/jama.2016.7207 (Abstract)

Valentini J, Ruppert D, Magez J, Stegbauer C, Bramesfeld A, Goetz K. Integrated care in German mental health services as benefit for relatives - a qualitative study. BMC Psychiatry 2016; 16: 48 - doi: 10.1186/s12888-016-0760-6 (PDF-Dokument)

Vassilev I, Rogers A, Kennedy A, Wensing M, Koetsenruijter J, Orlando R, Portillo MC, Culliford D. Social Network Type and Long-Term Condition Management Support: A Cross-Sectional Study in Six European Countries. PLoS One2016; 11: e0161027 - doi: 10.1371/journal.pone.0161027 (PDF-Dokument)



Baudendistel I, Nöst S, Frank Peters-Klimm F, Herzberg H, Scherer M, Blozik E, Joos S. Bridging the gap between patients' needs and quality indicators: a qualitative study with chronic heart failure patients. Patient Prefer Adherence 2015 (in press) 

Baudendistel I, Winkler E, Kamradt M, Brophy S, Längst G, Eckrich F, Heinze O, Bergh B, Szecsenyi J, Ose D. The patients' active role in managing a personal electronic health record: a qualitative analysis. Support Care Cancer. 2015 Feb 5 [Epub ahead of print] - doi: 10.1007/s00520-015-2620-1 (Abstract)

Baudendistel I, Winkler E, Kamradt M, Längst G, Eckrich F, Heinze O, Bergh B, Szecsenyi J, Ose D. Personal electronic health records: understanding user requirements and needs in chronic cancer care. J Med Internet Res. 2015 May 21;17(5): e121 - doi: 10.2196/jmir.3884 (PDF-Dokument)

Bozorgmehr K, Maier W, Brenner H,  Saum KU, Stock C, Miksch A, Holleczek B,  Szecsenyi J, Razum O. Social disparities in Disease Management Programmes for coronary heart disease in Germany: A cross-classified multilevel Analysis. J Epidemiol Community Health 2015; 0:1–11. doi:10.1136/jech-2014-204506 (PDF-Dokument)

Bozorgmehr K, San Sebastian M, Brenner H, Razum O, Maier W, Saum KU, Holleczek B, Miksch A, Szecsenyi J. Analysing horizontal equity in enrolment in Disease Management Programmes for coronary heart disease in Germany 2008-2010. Int J Equity Health 2015; 14: 28 - DOI 10.1186/s12939-015-0155-1 (PDF-Dokument)

Bozorgmehr K, Schneider C, Joos S. Equity in access to health care among asylum seekers in Germany: evidence from an exploratory population-based cross-sectional study. BMC Health Serv Res 2015; 15: 502 (PDF-Dokument)

Freund T, Peters-Klimm F, Boyd CM, Mahler C, Gensichen J, Erler A, Beyer M, Gondan M, Rochon J, Gerlach FM, Szecsenyi J. Medical Assistant-Based Care Management for High-Risk Patients in Small Primary Care Practices: A Cluster Randomized Clinical Trial. Ann Intern Med 2016; Feb 2. - doi: 10.7326/M14-2403. [Epub ahead of print] (Abstract)

Kamradt M, Baudendistel I, Längst G, Kiel M, Eckrich F, Winkler E, Szecsenyi J, Ose D. Collaboration and communication in colorectal cancer care: a qualitative study of the challenges experienced by patients and health care professionals. Fam Pract. 2015; 32: 686–693 - doi: 10.1093/fampra/cmv069 (PDF-Dokument)

Karstens S, Joos S, Hill JC, Krug K, Szecsenyi J, Steinhäuser J. General Practitioners Views of Implementing a Stratified Treatment Approach for Low Back Pain in Germany: A Qualitative Study. PLoS One 2015;10: e0136119 - doi: 10.1371/journal.pone.0136119. eCollection 20 (PDF-Dokument)

Schneider C, Joos S, Bozorgmehr K. Disparities in health and access to health care between asylum seekers and residents in Germany: a population-based cross-sectional feasibility study. BMJ Open 2015; 5: e008784 - doi: 10.1136/bmjopen-2015-008784 (PDF-Dokument)



Freund T, Heller G, Szecsenyi J. Krankenhausfälle für ambulant behandelbare Erkrankungen in Deutschland. Z Evid Fortbild Qual Gesundh wesen 2014, 108: 251-257

Jäger C, Freund T, Steinhäuser J, Aakhus E, Flottorp S, Godycki-Cwirko M, van Lieshout J, Krause J, Szecsenyi J, Wensing M. Tailored Implementation for Chronic Diseases (TICD): a protocol for process evaluation in cluster randomized controlled trials in five European countries. Trials 2014; 15: 87,  doi: 10.1186/1745-6215-15-87 (PDF-Dokument)

Kamradt M, Bozorgmehr K, Krisam J, Freund T, Kiel M, Qreini M, Flum E, Berger S, Besier W, Szecsenyi J, Ose D. Assessing self-management in patients with diabetes mellitus type 2 in Germany: validation of a German version of the Summary of Diabetes Self-Care Activities measure (SDSCA-G). Health Qual Life Out 2014, 12:185 - doi:10.1186/s12955-014-0185-1 (PDF-Dokument)

Karstens S, Froböse I, Weiler SW. Heilmittelversorgung in der ambulanten Physiotherapie bei Kniebeschwerden. Rehabilitation 2014 DOI 10.1055/s-0033-1358736 (Abstract)

Karstens S, Hermann K, Froböse I, Weiler SW. Predictors for patients with knee complaints receiving physiotherapy. European Journal of Physiotherapy 2014; 16: 10-16 (Abstract)

Krause J, Van Lieshout J, Klomp R, Huntink E, Aakhus E, Flottorp S, Jaeger C, Steinhaeuser J, Godycki-Cwirko M, Kowalczyk A, Agarwal S, Wensing M, Baker R. Identifying determinants of care for tailoring implementation in chronic diseases: an evaluation of different methods. Implement Sci 2014; 9: 102 - doi: 10.1186/s13012-014-0102-3 (PDF-Dokument)

Mahler CFreund T, Baldauf A, Jank S, Ludt SPeters-Klimm F, Haefeli E, Szecsenyi J. Das strukturierteMedikamentenmanagement in derHausarztpraxis — ein Beitrag zur Förderung der Arzneimitteltherapiesicherheit. Z Evid Fortbild Qual Gesundh wesen 2013 (in press)

Vassilev I, Rogers A, Kennedy A, Wensing M, Koetsenruijter J, Orlando R, Portillo MC, Culliford D. Social Network Type and Long-Term Condition Management Support: A Cross-Sectional Study in Six European Countries. PLoS One2016; 11: e0161027 - doi: 10.1371/journal.pone.0161027 (PDF-Dokument)

Wensing M, Huntink E, van Lieshout J, Godycki-Cwirko M, Kowalczyk A, Jäger C, Steinhäuser J, Aakhus E, Flottorp S, Eccles M, Baker R. Tailored implementation of evidence-based practice for patients with chronic diseases. PLoS One 2014 Jul 8;9(7), doi: 10.1371/journal.pone.0101981. eCollection 2014 (PDF-Dokument)



Bozorgmehr K, San Sebastian M. Trade Liberalisation and Tuberculosis Incidence: A longitudinal multi-level analysis in 22 high burden countries between 1990 and 2010. Health Policy Plan 2013, 1-24 (PDF-Dokument

Brenk-Franz K, Hibbard JH, Herrmann WJ, Freund T, Szecsenyi J, Djalali S, Steurer-Stey C, Sönnichsen A, Tiesler F, Storch M, Schneider N, Gensichen J. Validation of the German Version of the Patient Activation Measure 13 (PAM13-D) in an International Multicentre Study of Primary Care Patients. PLoS One 2013, published online 2013 Sep 30;8: e74786 (PDF-Dokument)

Freund T, Campbell S, Geißler S, Kunz CU, Mahler C, Peters-Klimm F, Szecsenyi J. Strategies for reducing potentially avoidable hospitalizations for ambulatory care–sensitive conditions. Ann Fam Med 2013; 363-370. doi 10.1370/afm.1498 (PDF-Dokument)

Freund T, Gondan M, Rochon J, Peters-Klimm FCampbell SWensing M, Szecsenyi J. Comparison of physician referral and insurance claims data-based risk prediction as approaches to identify patients for care management in primary care: an observational study. BMC Family Practice 2013, 14: 157 (PDF-Dokument)

Goetz K, Szecsenyi J, Laux G, Joos S, Beyer M, Miksch A. Wie beurteilen chronisch kranke Patienten Ihre Versorgung? Ergebnisse aus einer Patientenbefragung im Rahmen der Evaluation der Hausarztzentrierten Versorgung in Baden-Württemberg. Z Evid Fortbild Qual Gesundhwes 2013; 107: 379-385

Jäger C, Freund T, Steinhäuser J, Joos S, Wensing M, Szecsenyi J. A tailored implementation intervention to implement recommendations addressing polypharmacy in multimorbid patients: study protocol of a cluster randomized controlled Trial. Trials 2013 14: 420. doi: 10.1186/1745-6215-14-420 (PDF-Dokument)

Miksch A, Szecsenyi J. Entwicklung und Evaluation von Disease-Management-Programmen in Deutschland. Public Health Forum 2013; 21 (78): 4-6

Peters-Klimm FFreund T, Kunz CU, Laux G, Frankenstein L, Müller-Tasch T, Szecsenyi J. Determinants of heart failure self-care behaviour in community-based patients: A cross-sectional study. Eur J Cardiovasc Nurs 2013; 12: 167-176 (Abstract)

Schaefert R, Kirsch G, Kaufmann C, Hermann K, Szecsenyi J, Herzog W,  Bölter R. Neue Wege in der Versorgung von Patienten mit funktionellen Syndromen – Interdisziplinäre Gruppenbehandlung in der Hausarztpraxis: Eine qualitative Studie. Psychother Psychosom Med Psychol. 2013 Mar 8. [Epub ahead of print] DOI: 10.1055/s-0032-1323790 (Abstract)

Shadmi E, Freund T. Targeting patients for multimorbid care management interventions: the case for equity in high-risk patient identification. Int J Equity Health2013. Published online 2013 Aug 20; 12: 70 (PDF-Dokument)



Freund T, Kunz CU, Ose DSzecsenyi JPeters-Klimm F. Patterns of multimorbidity in primary care patients at high risk of future hospitalization. Popul Health Manag  2012 Feb 7. [Epub ahead of print] (Abstract

Freund TWensing M, Geißler S, Peters-Klimm FMahler C; Boyd CM, Szecsenyi J. Primary care physicians’ experiences with case finding for practice-based care management.  Am J Manag Care 2012; 18: e155-e161

Goetz KFreund T, Gensichen J, Miksch ASzecsenyi JSteinhaeuser J. Adaption and psychometric properties of the PACIC short form. Am J Manag Care 2012; 18: e55-e60

Goetz KSzecsenyi JCampbell S, Rosemann T, Rueter G, Raum E, Brenner H, Miksch A. The importance of social support for people with type 2 diabetes - a qualitative study with general practitioners, practice nurses and patients. GMS Psychosoc Med. 2012; 9 doi 10.3205/psm000080 (PDF-Dokument)

Hermann KBoelter REngeser PSzecsenyi JCampbell SMPeters-Klimm F. PalliPA: How can general practices support caregivers of patients at their end of life in a home-care setting? A study protocol. BMC Research Notes 2012, 5:233 doi:10.1186/1756-0500-5-233 (Provisional PDF)

Hermann K, Engeser P, Szecsenyi J, Miksch A. Palliative patients cared for at home by PAMINO-trained and other GPs – health-related quality of life as measured by QLQ-C15-PAL and POS. BMC Palliative Care 2012, 11:13 DOI: 10.1186/1472-684X-11-13 (PDF-Dokument)

Kirchberger I, Finger Th, Müller-Bühl U. A German version of the Intermittent Claudication Questionnaire: cultural adaptation and validation. Vasa 2012; 41:333-342 (Abstract)

Ludt S, van Lieshout J, Campbell SM, Rochon J, Ose DFreund TWensing MSzecsenyi J. Identifying factors associated with experiences of coronary heart disease patients receiving structured chronic care and counselling in European primary care. BMC Health Serv Res. 2012;12: 221. [Epub ahead of print] doi: 10.1186/1472-6963-12-221 (PDF-Dokument)

Mahler CHermann K, Horne R, Jank S,Haefeli WE, Szecsenyi J. Patients’ Beliefs about Medicines in a primary care setting in Germany. J Eval Clin Pract. 2012; 18: 409-413 doi: 10.1111/j.1365-2753.2010.01589.x (Abstract)

Mahler CHermann K, Jank S, Haefeli WE, Szecsenyi J. Can a feedback report and training session on medication counseling for general practitioners improve patient satisfaction with information on medicines? Patient Prefer Adherence 2012; 6: 179–186 doi: 10.2147/PPA.S27378 (PDF-Dokument)

Müller-Bühl U, Engeser P, Leutgeb R, Szecsenyi J. Eligibility of patients with peripheral arterial disease for participation in a community-based walking exercise program: a single centre experience. Int Angiol 2012; 31: 462-467 (Abstract)

Müller-Bühl ULeutgeb RBungartz JSzecsenyi JLaux G. Expenditure of chronic venous leg ulcer management in German primary care: results from a population-based study. Int Wound J. 2012 Feb 28. doi 10.1111/j.1742-481X.2012.00942.x. [Epub ahead of print] (Abstract)

Müller-Bühl ULeutgeb REngeser P, Achankeng E, Szecsenyi JLaux G. Varicose veins are a risk factor for deep venous thrombosis in general practice. Vasa 2012; 41: 360-365 (Abstract

Müller-Bühl ULeutgeb REngeser PSzecsenyi JLaux G. Prävalenz, lokale Komplikationen und Risikofaktoren der Beinvarikose in deutschen Hausarztpraxen. Phlebologie 2012; 41: 89-93 (Abstract)

Ose DFreund TLudt S. Prevention of cardiovascular diseases: creating a healthy environment [Editorial]. J Public Health 2012; 20: 1–3 doi 10.1007/s10389-011-0463-x (Abstract

Ose DFreund TUrban E, Kunz CU, Szecsenyi J, Miksch A. Comorbidity and patient-reported quality of care: an evaluation of the primary care based German disease management program for type 2 diabetes. J Public Health 2012;  DOI: 10.1007/s10389-011-0429-z (Abstract

Peters-Klimm FHalmer A, Flessa S, Szecsenyi JOse D. What drives costs of heart failure care in Germany? A health services cost analysis. J Public Health 2012; 20: April 2 doi10.1007/s10389-012-0501-3  [Epub ahead of print]

Peters-Klimm FLaux GCampbell S, Müller-Tasch T, Lossnitzer N., Schultz JH, Remppis A, Jünger J, Nikendei C. Physician and Patient Predictors of Evidence-Based Prescribing in Heart Failure: A Multilevel Study. PLoS ONE 7: e31082  doi:10.1371/journal.pone.0031082 (Link)

Peters-Klimm FNatanzon I, Müller-Tasch T, Ludt S, Nikendei C, Lossnitzer N, Szecsenyi J, Herzog W, Jünger J. Barrieren der Leitlinienumsetzung und Fortbildungsbedarf von Hausärzten zur Herzinsuffizienz: eine qualitative Studie. GMS Z Med Ausbild. 2012; 29: Doc46 (Link)

Vogel IMiksch AGoetz KOse DSzecsenyi JFreund T. The impact of perceived social support and sense of coherence on health-related quality of life in multimorbid primary care patients. Chronic Illn 2012; 8: 296-307 (Abstract)



Bölter RSteinhäuser JMiksch ASzecsenyi J. Das Chronic-Care-Modell in Deutschland – Entwicklung des Fragenbogens zur Versorgung chronisch kranker Patienten in der deutschen Hausarztpraxis (QCPC). Z Gerontol Geriat 2011; Suppl. 2, 44: 34-35 doi 10.1007/s00391-011-0252-8

Freund T,  Gensichen J, Goetz KSzecsenyi J, Mahler C. Evaluating self-efficacy for managing chronic disease: psychometric properties of the 6-item Self-Efficacy Scale in Germany. JJ Eval Clin Pract. 2011 Aug 23. doi: 10.1111/j.1365-2753.2011.01764.x. [Epub ahead of print] (Abstract)  

Goetz KCampbell S, Willms S, Rochon J, Klingenberg A, Szecsenyi J. How do chronically ill patients evaluate their medical care? An observational study with 46919 patients in 676 primary care practices. Int J Pers Cent Med 2011; 1: 338-346

Laux G, Nothacker M, Weinbrenner S, Störk S, Blozik E, Peters-Klimm FSzecsenyi J, Scherer M. Nutzung von Routinedaten zur Einschätzung der Versorgungsqualität: Eine kritische Beurteilung am Beispiel von Qualitätsindikatoren für die „Nationale Versorgungsleitlinie Chronische Herzinsuffizienz“. Z Evid Fortbild Qual Gesundh wesen 2011; 105: 21–26

Lieshout J, Goldfracht M, Campbell S, Ludt S, Wensing M. Primary care characteristics and population-orientated health care across Europe: an observational study. Br J Gen Pract 2011; 61: e22-30 (Abstract)

Mahler C, Jank S, Pruszydlo MG, Hermann KGärtner H, Kaltschmidt J, Ludt S, Bertsche T, Haefeli, WE, Szecsenyi J. HeiCare®: ein Projekt zur Verbesserung der sektorenübergreifenden Arzneimittelkommunikation. Dtsch Med Wochenschr 2011; 136: 1–6 (Abstract)

Steinhaeuser JMiksch AOse DGlassen KNatanzon ISzecsenyi JGoetz K. Questionnaire of Chronic Illness Care in Primary Care - psychometric properties and test-retest reliability. BMC Health Services Research 2011 Nov 2;11(1): 295 doi:10.1186/1472-6963-11-295 (PDF-Dokument)

Wensing M, Oxman A, Baker R, Godycki-Cwirko M, Flottorp S, Szecsenyi J, Grimshaw J, Eccles M. Tailored Implementation for chronic diseases (TICD): a project protocol. Implement Sci. 2011; 6: 103. [Epub ahead of print] (PDF-Dokument)



Böhlen F. Influenza-Patienten in der Hausarztpraxis: Möglichkeiten der Deskription und Analyse im Rahmen des CONTENT-Projekts. In: Laux GKühlein TGutscher ASzecsenyi J (Hrsg.). Versorgungsforschung in der Hausarztpraxis. Ergebnisse aus dem CONTENT-Projekt 2006 bis 2009. München: Urban&Vogel, 2010: 27-33 (ISBN 978-3-89935-268-9)

Bölter RKühlein TOse DGötz KFreund TSzecsenyi JMiksch A. Barrieren der Hausärzte gegen Evidenzbasierte Medizin - ein Verständnisproblem? Eine qualitative Studie mit Hausärzten. Z. ärztl. Fortbild. Qual.sich 2010; 492  doi: 10.1016/j.zefq.2010.02.015 

Bölter ROse DGötz KMiksch ASzecsenyi JFreund T. Einbeziehung nichtärztlicher Gesundheitsberufe in die Primärversorgung chronisch kranker Patienten. Chancen und Barrieren aus Sicht deutscher Hausärzte. Med. Klinik 2010; 105: 7-12

Engeser PHermann K. Pharmakotherapie mit Opioiden in der Hausarztpraxis. In: Laux GKühlein TGutscher ASzecsenyi J (Hrsg.). Versorgungsforschung in der Hausarztpraxis. Ergebnisse aus dem CONTENT-Projekt 2006 bis 2009. München: Urban&Vogel, 2010:39-43  (ISBN 978-3-89935-268-9)

Freund TSzecsenyi JOse D. Charakteristika von eingeschriebenen Versicherten eines flächendeckenden Vertrages zur Hausarztzentrierten Versorgung. Med Klinik 2010; 105: 808-811 (Abstract)

Götz, K. Soziale Probleme in der Primärversorgung. In: Laux GKühlein TGutscher ASzecsenyi J (Hrsg.). Versorgungsforschung in der Hausarztpraxis. Ergebnisse aus dem CONTENT-Projekt 2006 bis 2009. München: Urban&Vogel, 2010: 64-66  (ISBN 978-3-89935-268-9)

Joos SMusselmann B. Einsatz von Phytotherapeutika in der hausärztlichen Praxis. Laux GKühlein TGutscher ASzecsenyi J (Hrsg.). Versorgungsforschung in der Hausarztpraxis. Ergebnisse aus dem CONTENT-Projekt 2006 bis 2009. München: Urban&Vogel, 2010: 44-47 (ISBN 978-3-89935-268-9)

Kühlein T. Potentiale zur Reduzierung von Krankenhauseinweisungen aus dem primärärztlichen Sektor. In: Laux GKühlein TGutscher ASzecsenyi J (Hrsg.). Versorgungsforschung in der Hausarztpraxis. Ergebnisse aus dem CONTENT-Projekt 2006 bis 2009. München: Urban&Vogel, 2010: 48-55 (ISBN 978-3-89935-268-9)

Laux G. Unterschiede in der Pharmakotherapie für gesetzlich und privat versicherte Patienten am Beispiel von Hypertonie-Episoden. In: Laux GKühlein TGutscher ASzecsenyi J (Hrsg.). Versorgungsforschung in der Hausarztpraxis. Ergebnisse aus dem CONTENT-Projekt 2006 bis 2009. München: Urban&Vogel, 2010: 21-26 (ISBN 978-3-89935-268-9)

Laux GKühlein TGutscher ASzecsenyi J (Hrsg.). Versorgungsforschung in der Hausarztpraxis. Ergebnisse aus dem CONTENT-Projekt 2006 bis 2009. München: Urban&Vogel, 2010 (ISBN 978-3-89935-268-9)

Laux GMiksch A. Grenzen und Chancen der Verwendung von Routinedaten für die Versorgungsforschung. In: Laux GKühlein TGutscher ASzecsenyi J (Hrsg.). Versorgungsforschung in der Hausarztpraxis. Ergebnisse aus dem CONTENT-Projekt 2006 bis 2009. München: Urban&Vogel, 2010: 18-26 (ISBN 978-3-89935-268-9)

Leutgeb R. Krankenkassen-Rabattverträge: Dokumentation von Risiken durch Präparatewechsel mit der CONTENT-Software. In: Laux GKühlein TGutscher ASzecsenyi J (Hrsg.). Versorgungsforschung in der Hausarztpraxis. Ergebnisse aus dem CONTENT-Projekt 2006 bis 2009. München: Urban&Vogel, 2010: 62-63 (ISBN 978-3-89935-268-9)

Müller-Bühl U. Inanspruchnahme primärärztlicher Leistungen durch Patienten mit PAVK. In: Laux GKühlein TGutscher ASzecsenyi J (Hrsg.). Versorgungsforschung in der Hausarztpraxis. Ergebnisse aus dem CONTENT-Projekt 2006 bis 2009. München: Urban&Vogel, 2010: 56-61  (ISBN 978-3-89935-268-9)

Peters-Klimm FCampbell SHermann K, Kunz C, Mueller-Tasch T, Szecsenyi J (on Behalf of the Competence Network Heart Failure). Case management for patients with chronic systolic heart failure in primary care: The HICMan exploratory randomised controlled trial. Trials 2010; 11: 56 doi:10.1186/1745-6215-11-56

Peters-Klimm F; Kunz CU, Laux GSzecsenyi J, MÃller-Tasch T. Patient- and provider-related determinants of generic and specific health-related quality of life of patients with chronic systolic heart failure in primary care: a cross-sectional study. Health Qual Life Outcomes 2010; 8: 98 doi:10.1186/1477-7525-8-98 (Link)

Steinhäuser J. Inhaltliche Verbesserung weiterbildungsbegleitender Lerngruppen durch Daten de CONTENT-Projekts. In: Laux GKühlein TGutscher ASzecsenyi J (Hrsg.). Versorgungsforschung in der Hausarztpraxis. Ergebnisse aus dem CONTENT-Projekt 2006 bis 2009. München: Urban&Vogel, 2010: 76-79 (ISBN 978-3-89935-268-9)

Szecsenyi J. Programme de disease management et organisation des soins pimaires en Allemagne. Rev Franc Affaires Sociales 2010; 64: 81-96

Urban E. Medikamentenpläne zur Unterstützung leitliniengerechter Versorgung von Patienten mit koronarer Herzkrankheit. In: Laux GKühlein TGutscher ASzecsenyi J (Hrsg.). Versorgungsforschung in der Hausarztpraxis. Ergebnisse aus dem CONTENT-Projekt 2006 bis 2009. München: Urban&Vogel, 2010: 34-38 (ISBN 978-3-89935-268-9)

Urban E, Glassen K, Miksch A. Diabetes vermeiden. Prävention, Screening und Patientenselbstmanagement. Diabetes aktuell 2010; 8: 307-311



Hensler S, Heinemann D, Becker MT, Ackermann H, Wiesemann A, Abholz HH, Engeser P. Chronic pain in german general practice. Pain Med. 2009; 10: 1408-1415 (Abstract)

Leutgeb RMahler CLaux G, Ärztenetz Weschnetz, Szecsenyi J. Krankenkassen-Rabattverträge: Probleme und Risiken für den Hausarzt bei der Betreuung chronisch kranker Patienten. Dtsch med Wochenschr 2009; 134: 181-186 (Abstract

Miksch AHermann KRoelz AJoos SSzecsenyi JOse DRosemann T. Additional impact of concomitant hypertension and osteoarthritis on quality of life among patients with type 2 diabetes in primary care in Germany - a cross sectional survey. Health Qual Life Outcomes 2009; 7: 19 (PDF-Dokument

Olbort RMahler CCampbell S, Reuschenbach B, Mueller-Tasch T, Szecsenyi JPeters-Klimm F. Doctors’ assistants’ views of case management to improve chronic heart failure care in general practice: a qualitative study. J Adv Nurs 2009; 65: 799-808 (PDF-Dokument

Ose DWensing MSzecsenyi JJoos SHermann KMiksch A. Impact of primary care-based disease management on the health-related quality of life in patients with type 2 diabetes and co-morbidity. Diabetes Care 2009; 32: 1-7 [Epub ahead of print] doi:10.2337/dc08-2223 (Provisional PDF-Dokument)



Laux GKuehlein TRosemann TSzecsenyi J. Co- and multimorbidity patterns in primary care based on episodes of care: results from the German CONTENT project. BMC Health Serv Res 2008; 8: 14 (PDF-Dokument

Rosemann TKuehlein TLaux GSzecsenyi J. Factors associated with physical activity of patients with osteoarthritis of the hip and knee. J Eval Clin Pract 2008; 14: 288-293 (Abstract)

Rosemann TLaux GSzecsenyi J, Grol R. The Chronic Care Model: Congruency and predictors among primary care patients with osteoarthritis. Qual Saf H Care 2008; 17: 442-446 (Abstract

Rosemann TLaux GSzecsenyi JWensing M, Grol R. Pain and osteoarthritis in primary care: factors associated with pain perception in a sample of 1,021 patients. Pain Med. 2008; 9: 903-910 (Abstract)

Schneider A, Löwe B, Meyer FJ, Biessecker K, Joos SSzecsenyi J. Depression and panic disorder as predictors of health outcomes for patients with asthma in primary care. Respir Med 2008; 102: 359-366 (Abstract



Müller-Tasch T, Peters-Klimm F, Schellberg D, Holzapfel N, Barth A, Jünger J, Szecsenyi J, Herzog W. Depression is a major determinant of quality of life in patients with chronic systolic heart failure in general practice. .J Card Fail. 2007;13: 818-24 (Abstract

Rosemann T, Backenstrass M, Rosemann A, Joest K, Szecsenyi JLaux G. Predictors of depression in a sample of 1,021 primary care patients with osteoarthritis . Arthritis Rheum 2007; 57: 415-422 (Abstract