Kliniken &… Kliniken Chirurgische Klinik… Herzchirurgie Über uns Mitarbeiter Publikationen…

 

Publikationen

 

Prof. Dr. med. Gábor B. Szabó, Ph.D.

 


2024

Saemann L, Wächter K, Gharpure N, Pohl S, Hoorn F, Korkmaz-Icöz S, Karck M, Veres G, Simm A, Szabó G (2024)

HTK vs. HTK-N for Coronary Endothelial Protection during Hypothermic, Oxygenated Perfusion of Hearts Donated after Circulatory Death.

Int J Mol Sci. 2024 Feb 13;25(4):2262. doi: 10.3390/ijms25042262. PMID: 38396938 Free PMC article.
 

Saemann L, Wächter K, Georgevici AI, Pohl S, Hoorn F, Veres G, Korkmaz-Icöz S, Karck M, Simm A, Szabó G (2024)

Transcriptomic Changes in the Myocardium and Coronary Artery of Donation after Circulatory Death Hearts following Ex Vivo Machine Perfusion.

Int J Mol Sci. 2024 Jan 19;25(2):1261. doi: 10.3390/ijms25021261. PMID: 38279260 Free PMC article.
 

Benke K, Stengl R, Stark KA, Bai Y, Radovits T, Loganathan S, Korkmaz-Icöz S, Csonka M, Karck M, Szabó G, Veres G (2024)

Zinc-aspirin preconditioning reduces endothelial damage of arterial grafts in a rodent model of revascularization.

Front Cardiovasc Med. 2024 Jan 4;10:1288128. doi: 10.3389/fcvm.2023.1288128. eCollection 2023. PMID: 38239873 Free PMC article.

 

Saemann L, Stiller M, Willsch J, Schultze T, Matin M, Veres G, Szabó G (2024)

First experience with the new extracorporeal membrane oxygenation system Colibrì.

Artif Organs. 2024 Jan;48(1):103-109. doi: 10.1111/aor.14671. Epub 2023 Nov 23. PMID: 37994562 
 

2023

Liu B, Korkmaz B, Kraft P, Mayer T, Sayour AA, Grundl MA, Domain R, Karck M, Szabó G, Korkmaz-Icöz S (2023)

Pharmacological inhibition of the cysteine protease cathepsin C improves graft function after heart transplantation in rats.

J Transl Med. 2023 Nov 9;21(1):799. doi: 10.1186/s12967-023-04659-6. PMID: 37946197 Free PMC article.
 

Nersesian G, Ott S, Fardman A, Lanmueller P, Lewin D, Bernhardt A, Emrich F, Faerber G, Szabó G, Oezkur M, Panholzer B, Rojas SV, Saeed D, Schmack B, Warnecke G, Zimpfer D, Grubitzsch H, Falk V, Potapov E (2023)

Temporary Mechanical Circulatory Support in Cardiogenic Shock Patients after Cardiac Procedures: Selection Algorithm and Weaning Strategies.

Life (Basel). 2023 Oct 12;13(10):2045. doi: 10.3390/life13102045. PMID: 37895427 Free PMC article. 
 

Ruppert M, Korkmaz-Icöz S, Benczik B, Ágg B, Nagy D, Bálint T, Sayour AA, Oláh A, Barta BA, Benke K, Ferdinandy P, Karck M, Merkely B, Radovits T, Szabó G (2023)

Pressure overload-induced systolic heart failure is associated with characteristic myocardial microRNA expression signature and post-transcriptional gene regulation in male rats.

Sci Rep. 2023 Sep 26;13(1):16122. doi: 10.1038/s41598-023-43171-1. PMID: 37752166 Free PMC article.
 

Saemann L, Wernstedt L, Pohl S, Stiller M, Willsch J, Hofmann B, Veres G, Simm A, Szabó G (2023)

Impact of Age on Endothelial Function of Saphenous Vein Grafts in Coronary Artery Bypass Grafting.

J Clin Med. 2023 Aug 22;12(17):5454. doi: 10.3390/jcm12175454. PMID: 37685521 Free PMC article. 
 

Saemann L, Naujoks P, Hartrumpf L, Pohl S, Simm A, Szabó G (2023)

Sex-Specific Protection of Endothelial Function after Vascular Ischemia/Reperfusion Injury by the Senomorphic Agent Ruxolitinib.

Int J Mol Sci. 2023 Jul 21;24(14):11727. doi: 10.3390/ijms241411727. PMID: 37511486 Free PMC article. 
 

Saemann L, Georgevici AI, Hoorn F, Gharpure N, Veres G, Korkmaz-Icöz S, Karck M, Simm A, Wenzel F, Szabó G (2023)

Improving Diastolic and Microvascular Function in Heart Transplantation with Donation after Circulatory Death.

Int J Mol Sci. 2023 Jul 17;24(14):11562. doi: 10.3390/ijms241411562. PMID: 37511318 Free PMC article.
 

Korkmaz-Icöz S, Abulizi S, Li K, Korkmaz B, Georgevici AI, Sayour AA, Loganathan S, Canoglu H, Karck M, Szabó G (2023)

Preservation solution Custodiol containing human alpha-1-antitrypsin improves graft recovery after prolonged cold ischemic storage in a rat model of heart transplantation.

Front Immunol. 2023 Jun 22;14:1155343. doi: 10.3389/fimmu.2023.1155343. eCollection 2023. PMID: 37426668 Free PMC article.
 

Ding Q, Loganathan S, Zhou P, Sayour AA, Brlecic P, Radovits T, Domain R, Korkmaz B, Karck M, Szabó G, Korkmaz-Icöz S (2023)

Alpha-1-Antitrypsin Protects Vascular Grafts of Brain-Dead Rats Against Ischemia/Reperfusion Injury.

J Surg Res. 2023 Mar;283:953-964. doi: 10.1016/j.jss.2022.11.047. Epub 2022 Dec 9. PMID: 36915024

 

Xu L, Zeng Z, Niu C, Liu D, Lin S, Liu X, Szabó G, Lu J, Zheng S, Zhou P (2023)

Normothermic ex vivo heart perfusion with NLRP3 inflammasome inhibitor Mcc950 treatment improves cardiac function of circulatory death hearts after transplantation.

Front Cardiovasc Med. 2023 Mar 17;10:1126391. doi: 10.3389/fcvm.2023.1126391. eCollection 2023. PMID: 37008319 Free PMC article.

 

Saemann L, Hoorn F, Kraft P, Großkopf A, Veres G, Wenzel F, Korkmaz-Icöz S, Karck M, Simm A, Szabo G (2023)

Left-ventricular Contraction and Relaxation of Donation after Circulatory Death Hearts Remain Stable During Early Reperfusion after Ex vivo Machine Perfusion with HTK-N but not with Blood.

KARDIOTECHNIK 2023; 032(2):044-048 
 

2022

Saemann L, Kohl M, Veres G, Korkmaz-Icöz S, Großkopf A, Karck M, Simm A, Wenzel F, Szabó G (2022)

Prediction Model for Contractile Function of Circulatory Death Donor Hearts Based on Microvascular Flow Shifts During Ex Situ Hypothermic Cardioplegic Machine Perfusion.

J Am Heart Assoc. 2022 Dec 6;11(23):e027146. doi: 10.1161/JAHA.122.027146. Epub 2022 Nov 16. PMID: 36382941 Free PMC article. Review.
 

Saemann L, Hoorn F, Georgevici AI, Pohl S, Korkmaz-Icöz S, Veres G, Guo Y, Karck M, Simm A, Wenzel F, Szabó G (2022)

Cytokine Adsorber Use during DCD Heart Perfusion Counteracts Coronary Microvascular Dysfunction.

Antioxidants (Basel). 2022 Nov 17;11(11):2280. doi: 10.3390/antiox11112280. PMID: 36421466 Free PMC article.

 

Korkmaz-Icöz S, Sistori G, Loganathan S, Sayour AA, Brlecic P, Radovits T, Brune M, Karck M, Szabó G (2022)

Bone Marrow Culture-Derived Conditioned Medium Recovers Endothelial Function of Vascular Grafts following In Vitro Ischemia/Reperfusion Injury in Diabetic Rats.

Stem Cells Int. 2022 Oct 14;2022:7019088. doi: 10.1155/2022/7019088. eCollection 2022. PMID: 36277042

 

Veres G, Benke K, Stengl R, Weber P, Marina E, Szabó G, Karck M (2022)

Long-Term Outcomes Stratified by Age in Patients with a Mechanical versus Biological Mitral Valve Replacement.

J Cardiovasc Dev Dis. 2022 Oct 6;9(10):339. doi: 10.3390/jcdd9100339. PMID: 36286291

 

Szabó G, Brlecic P, Loganathan S, Wagner F, Rastan A, Doenst T, Karck M, Veres G (2022)

Custodiol-N versus Custodiol: a prospective randomized double-blind multicenter phase III trial in patients undergoing elective coronary bypass surgery.

Eur J Cardiothorac Surg. 2022 Oct 4;62(5):ezac287.doi: 10.1093/ejcts/ezac287. PMID: 35579350

 

Korkmaz-Icöz S, Schwär M, Loganathan S, Wächter K, Georgevici AI, Kraft P, Mayer T, Simm A, Karck M, Szabó G (2022)

Bread crust extract protects rats’ vascular grafts from in vitro ischemia/reperfusion injury.

J Funct Foods 2022 Aug 8 ;95:105187

 

Ruppert M, Barta BA, Korkmaz-Icöz S, Loganathan S, Oláh A, Sayour AA, Benke K, Nagy D, Bálint T, Karck M, Schilling O, Merkely B, Radovits T, Szabó G (2022)

Sex similarities and differences in the reverse and anti-remodeling effect of pressure unloading therapy in a rat model of aortic banding and debanding.

Am J Physiol Heart Circ Physiol. 2022 Jul 1;323(1):H204-H222.doi: 10.1152/ajpheart.00654.2021. Epub 2022 Jun 10.

 

Szabó G, Loganathan S, Korkmaz-Icöz S, Balogh Á, Papp Z, Brlecic P, Hegedüs P, Radovits T, Karck M, Merkely B, Veres G (2022)

Improvement of Left Ventricular Graft Function Using an Iron-Chelator-Supplemented Bretschneider Solution in a Canine Model of Orthotopic Heart Transplantation.

Int J Mol Sci. 2022 Jul 5;23(13):7453. doi: 10.3390/ijms23137453. PMID: 35806458 Free PMC article


Winterhalter PR, Wirkner M, Bartling B, Wächter K, Urazova A, Großkopf A, Diez C, Szabó G, Simm A (2022)

Sex-dependent deterioration of cardiac function and molecular alterations in age- and disease-associated RAGE overexpression.

Mech Ageing Dev. 2022 Apr;203:111635. doi: 10.1016/j.mad.2022.111635. Epub 2022 Jan 31. PMID: 35114269

 

Diab M, Lehmann T, Bothe W, Akhyari P, Platzer S, Wendt D, Deppe AC, Strauch J, Hagel S, Günther A, Faerber G, Sponholz C, Franz M, Scherag A, Velichkov I, Silaschi M, Fassl J, Hofmann B, Lehmann S, Schramm R, Fritz G, Szabo G, Wahlers T, Matschke K, Lichtenberg A, Pletz MW, Gummert JF, Beyersdorf F, Hagl C, Borger MA, Bauer M, Brunkhorst FM, Doenst T; REMOVE Trial Investigators (2022)

Cytokine Hemoadsorption During Cardiac Surgery versus Standard Surgical Care for Infective Endocarditis (REMOVE): Results from a Multicenter, Randomized, Controlled Trial.

Circulation. 2022 Mar 29;145(13):959-968.doi: 10.1161/CIRCULATIONAHA.121.056940. Epub 2022 Feb 25.

 

Veres G, Benke K, Stengl R, Bai Y, Stark KA, Sayour AA, Radovits T, Loganathan S, Korkmaz-Icöz S, Karck M, Szabó G (2022)

Aspirin Reduces Ischemia-Reperfusion Injury Induced Endothelial Cell Damage of Arterial Grafts in a Rodent Model.

Antioxidants (Basel). 2022 Jan 18;11(2):177. doi: 10.3390/antiox11020177. PMID: 35204060 Free PMC article.

 

2021

Li J, Peng Q, Yang R, Li K, Zhu P, Zhu Y, Zhou P, Szabó G, Zheng S (2021)

Application of Mesenchymal Stem Cells During Machine Perfusion: An Emerging Novel Strategy for Organ Preservation.

Front Immunol. 2021 Dec 22;12:713920. doi: 10.3389/fimmu.2021.713920. eCollection 2021. PMID: 35024039 Free PMC article. Review.
 

Saemann L, Zubarevich A, Wenzel F, Soethoff J, Loganathan S, Korkmaz-Icöz S, Karck M, Szabó G, Veres G (2021)

Impact of skeletonized harvesting of the internal thoracic artery on intrasternal microcirculation considering preparation quality.

Interact Cardiovasc Thorac Surg. 2021 Oct 29;33(5):779-783.doi: 10.1093/icvts/ivab160.

 

Wächter K, Navarrete Santos A, Großkopf A, Baldensperger T, Glomb MA, Szabó G, Simm A (2021)

AGE-Rich Bread Crust Extract Boosts Oxidative Stress Interception via Stimulation of the NRF2 Pathway.

Nutrients. 2021 Oct 29;13(11):3874. doi: 10.3390/nu13113874. PMID: 34836129 Free PMC article.

 

Korkmaz-Icöz S, Ballikaya B, Soethoff J, Kraft P, Sayour AA, Radovits T, Loganathan S, Karck M, Szabó G, Veres G (2021)

Graft Preservation Solution DuraGraft® Alleviates Vascular Dysfunction Following In Vitro Ischemia/Reperfusion Injury in Rats.

Pharmaceuticals (Basel). 2021 Oct 9;14(10):1028. doi: 10.3390/ph14101028. PMID: 34681252 Free PMC article.
 

Thielmann M, Corteville D, Szabo G, Swaminathan M, Lamy A, Lehner LJ, Brown CD, Noiseux N, Atta MG, Squiers EC, Erlich S, Rothenstein D, Molitoris B, Mazer CD (2021)

Teprasiran, a Small Interfering RNA, for the Prevention of Acute Kidney Injury in High-Risk Patients Undergoing Cardiac Surgery: A Randomized Clinical Study.

Circulation. 2021 Oct 5;144(14):1133-1144. doi: 10.1161/CIRCULATIONAHA.120.053029. Epub 2021 Sep 3. PMID: 34474590 Free PMC article. Clinical Trial.

 

Saemann L, Korkmaz-Icöz S, Hoorn F, Veres G, Kraft P, Georgevici AI, Brune M, Guo Y, Loganathan S, Wenzel F, Karck M, Szabó G (2021)

Reconditioning of circulatory death hearts by ex-vivo machine perfusion with a novel HTK-N preservation solution.

J Heart Lung Transplant. 2021 Oct;40(10):1135-1144. doi: 10.1016/j.healun.2021.07.009. Epub 2021 Jul 26. PMID: 34420849

 

Fagyas M, Bánhegyi V, Úri K, Enyedi A, Lizanecz E, Mányiné IS, Mártha L, Fülöp GÁ, Radovits T, Pólos M, Merkely B, Kovács Á, Szilvássy Z, Ungvári Z, Édes I, Csanádi Z, Boczán J, Takács I, Szabó G, Balla J, Balla G, Seferovic P, Papp Z, Tóth A (2021)

Changes in the SARS-CoV-2 cellular receptor ACE2 levels in cardiovascular patients: a potential biomarker for the stratification of COVID-19 patients.

Geroscience. 2021 Oct;43(5):2289-2304. doi: 10.1007/s11357-021-00467-2. Epub 2021 Oct 21. PMID: 34674152 Free PMC article.


Korkmaz-Icöz S, Benker MI, Li S, Loganathan S, Karft P, Mayer T, Schubach S, Brlecic P, Sayour AA, Radovits T, Karck M, Szabo G (2021)

Vascular reactivity in old spontaneously hypertensive stroke-prone rats - effects of in vitro ischemia/reperfusion injury.

J Surg Res 2021; 4(3): 358-398

 

Korkmaz-Icöz S, Akca D, Li S, Loganathan S, Brlecic P, Ruppert M, Sayour AA, Simm A, Brune M, Radovits T, Karck M, Szabó G (2021)

Left-ventricular hypertrophy in 18-month-old donor rat hearts was not associated with graft dysfunction in the early phase of reperfusion after cardiac transplantation-gene expression profiling.

Geroscience. 2021 Aug;43(4):1995-2013.doi: 10.1007/s11357-021-00348-8. Epub 2021 Apr 19.

 

Korkmaz-Icöz S, Kocer C, Sayour AA, Kraft P, Benker MI, Abulizi S, Georgevici AI, Brlecic P, Radovits T, Loganathan S, Karck M, Szabó G (2021)

The Sodium-Glucose Cotransporter-2 Inhibitor Canagliflozin Alleviates Endothelial Dysfunction Following In Vitro Vascular Ischemia/Reperfusion Injury in Rats.

Int J Mol Sci. 2021 Jul 21;22(15):7774. doi: 10.3390/ijms22157774. PMID: 34360539 Free PMC article.


Al-Maisary S, Farag M, Te Gussinklo WH, Kremer J, Pleger ST, Leuschner F, Karck M, Szabo G, Arif R (2021)

Are Sutureless and Rapid-Deployment Aortic Valves a Serious Alternative to TA-TAVI? A Matched-Pairs Analysis.

J Clin Med. 2021 Jul 12;10(14):3072. doi: 10.3390/jcm10143072. PMID: 34300238

 

Bánhegyi V, Enyedi A, Fülöp GÁ, Oláh A, Siket IM, Váradi C, Bottyán K, Lódi M, Csongrádi A, Umar AJ, Fagyas M, Czuriga D, Édes I, Pólos M, Merkely B, Csanádi Z, Papp Z, Szabó G, Radovits T, Takács I, Tóth A (2021)

Human Tissue Angiotensin Converting Enzyme (ACE) Activity Is Regulated by Genetic Polymorphisms, Posttranslational Modifications, Endogenous Inhibitors and Secretion in the Serum, Lungs and Heart.

Cells. 2021 Jul 6;10(7):1708. doi: 10.3390/cells10071708. PMID: 34359878 Free PMC article.


Saemann L, Großkopf A, Hoorn F, Veres G, Guo Y, Korkmaz-Icöz S, Karck M, Simm A, Wenzel F, Szabó G (2021)

Relationship of Laser-Doppler-Flow and coronary perfusion and a concise update on the importance of coronary microcirculation in donor heart machine perfusion.

Clin Hemorheol Microcirc. 2021;79(1):121-128. doi: 10.3233/CH-219116. PMID: 34487033

 

Stengl R, Ágg B, Pólos M, Mátyás G, Szabó G, Merkely B, Radovits T, Szabolcs Z, Benke K (2021)

Potential predictors of severe cardiovascular involvement in Marfan syndrome: the emphasized role of genotype-phenotype correlations in improving risk stratification-a literature review.

Orphanet J Rare Dis. 2021 May 31;16(1):245. doi: 10.1186/s13023-021-01882-6. PMID: 34059089 Free PMC article. Review.

 

Korkmaz-Icöz S, Sun X, Li S, Brlecic P, Loganathan S, Ruppert M, Sayour AA, Radovits T, Karck M, Szabó G (2021)

Conditioned Medium from Mesenchymal Stem Cells Alleviates Endothelial Dysfunction of Vascular Grafts Submitted to Ischemia/Reperfusion Injury in 15-Month-Old Rats.

Cells. 2021 May 17;10(5):1231.doi: 10.3390/cells10051231.


Veres G, Bai Y, Stark KA, Schmidt H, Radovits T, Loganathan S, Korkmaz-Icöz S, Szabó G (2021)

Pharmacological activation of soluble guanylate cyclase improves vascular graft function.

Interact Cardiovasc Thorac Surg. 2021 May 10;32(5):803-811. doi: 10.1093/icvts/ivaa329. PMID: 33515043

 

Saemann L, Wenzel F, Kohl M, Korkmaz-Icöz S, Hoorn F, Loganathan S, Guo Y, Ding Q, Zhou P, Veres G, Karck M, Szabó G (2021)

Monitoring of perfusion quality and prediction of donor heart function during ex-vivo machine perfusion by myocardial microcirculation versus surrogate parameters.

J Heart Lung Transplant. 2021 May;40(5):387-391. doi: 10.1016/j.healun.2021.02.013. Epub 2021 Feb 22. PMID: 33726982
 

Pleger ST, Geis N, Kreusser M, Abu-Sharar H, Sebening C, Szabo G, Katus HA, Raake PWJ (2021)

Percutaneous mitral valve repair in recurrent severe mitral valve regurgitation after mitral annuloplasty : MitraClip-in-the-ring as a complementary strategy.

Herz. 2021 Apr;46(Suppl 1):54-60. doi: 10.1007/s00059-019-04868-0. Epub 2019 Nov 26. PMID: 31773184
 

Korkmaz-Icöz S, Zhou P, Guo Y, Loganathan S, Brlecic P, Radovits T, Sayour AA, Ruppert M, Veres G, Karck M, Szabó G (2021)

Mesenchymal stem cell-derived conditioned medium protects vascular grafts of brain-dead rats against in vitro ischemia/reperfusion injury.

Stem Cell Res Ther. 2021 Feb 24;12(1):144. doi: 10.1186/s13287-021-02166-3. PMID: 33627181
 

2020

Saemann L, Karck M, Korkmaz-Icöz S, Wenzel F, Szabó G (2020)

Ethical Decision Diagrams on Donation After Cardiocirculatory Death Heart Transplantation Considering Organ Preservation Techniques.

Transplant Direct. 2020 Oct 19;6(11):e617.doi: 10.1097/TXD.0000000000001075. eCollection 2020 Nov.

 

Korkmaz-Icöz S, Li K, Loganathan S, Ding Q, Ruppert M, Radovits T, Brlecic P, Sayour AA, Karck M, Szabó G (2020)

Brain-dead donor heart conservation with a preservation solution supplemented by a conditioned medium from mesenchymal stem cells improves graft contractility after transplantation.

Am J Transplant. 2020 Oct;20(10):2847-2856.doi: 10.1111/ajt.15843. Epub 2020 Apr 9.

 

Saemann L, Guo Y, Ding Q, Zhou P, Karck M, Szabó G, Wenzel F (2020)

Machine perfusion of circulatory determined death hearts: A scoping review.

Transplant Rev (Orlando). 2020 Jul;34(3):100551. doi: 10.1016/j.trre.2020.100551. Epub 2020 May 12.

 

Benke K, Németh BT, Sayour AA, Stark KA, Oláh A, Ruppert M, Szabó G, Korkmaz-Icöz S, Horváth EM, Benkő R, Hartyánszky I, Szabolcs Z, Merkely B, Radovits T (2020)

Stimulation of soluble guanylate cyclase improves donor organ function in rat heart transplantation.

Sci Rep. 2020 Mar 24;10(1):5358. doi: 10.1038/s41598-020-62156-y.

 

2019

Loganathan S, Guo Y, Jiang W, Radovits T, Ruppert M, Sayour AA, Brune M, Brlecic P, Gude P, Georgevici AI, Yard B, Karck M, Korkmaz-Icöz S, Szabó G (2019)

N-octanoyl dopamine is superior to dopamine in protecting graft contractile function when administered to the heart transplant recipients from brain-dead donors.

Pharmacol Res. 2019 Dec;150:104503. doi: 10.1016/j.phrs.2019.104503. Epub 2019 Oct 16.

 

Pleger ST, Geis N, Kreusser M, Abu-Sharar H, Sebening C, Szabo G, Katus HA, Raake PWJ (2019)

Percutaneous mitral valve repair in recurrent severe mitral valve regurgitation after mitral annuloplasty : MitraClip-in-the-ring as a complementary strategy.

Herz. 2019 Nov 26. doi: 10.1007/s00059-019-04868-0. [Epub ahead of print]

 

Schmidt C, Wiedmann F, Beyersdorf C, Zhao Z, El-Battrawy I, Lan H, Szabo G, Li X, Lang S, Korkmaz-Icöz S, Rapti K, Jungmann A, Ratte A, Müller OJ, Karck M, Seemann G, Akin I, Borggrefe M, Zhou XB, Katus HA, Thomas D (2019)

Genetic Ablation of TASK-1 (Tandem of P Domains in a Weak Inward Rectifying K+ Channel-Related Acid-Sensitive K+ Channel-1) (K2P3.1) K+ Channels Suppresses Atrial Fibrillation and Prevents Electrical Remodeling.

Circ Arrhythm Electrophysiol. 2019 Sep;12(9):e007465. doi: 10.1161/CIRCEP.119.007465. Epub 2019 Sep 13.

 

Kremer J, Farag M, Zaradzki M, Szabó G, Ruhparwar A, Kallenbach K, Karck M, Arif R (2019)

The reimplantation valve-sparing aortic root replacement technique for patients with Marfan syndrome: A single-center experience.

Sci Rep. 2019 Aug 19;9(1):12021. doi: 10.1038/s41598-019-48572-9.

 

Farag M, Veres G, Szabó G, Ruhparwar A, Karck M, Arif R (2019)

Hyperbilirubinaemia after cardiac surgery: the point of no return.

ESC Heart Fail. 2019 Aug;6(4):694-700. doi: 10.1002/ehf2.12447. Epub 2019 May 16.

 

Ruppert M, Korkmaz-Icöz S, Loganathan S, Jiang W, Oláh A, Sayour AA, Barta BA, Karime C, Merkely B, Karck M, Radovits T, Szabó G (2019)

Incomplete structural reverse remodeling from late-stage left ventricular hypertrophy impedes the recovery of diastolic but not systolic dysfunction in rats.

J Hypertens. 2019 Jun;37(6):1200-1212. doi: 10.1097/HJH.0000000000002042.

 

Bekeredjian R, Szabo G, Balaban Ü, Bleiziffer S, Bauer T, Ensminger S, Frerker C, Herrmann E, Beyersdorf F, Hamm C, Beckmann A, Möllmann H, Karck M, Katus HA, Walther T (2019)

Patients at low surgical risk as defined by the Society of Thoracic Surgeons Score undergoing isolated interventional or surgical aortic valve implantation: in-hospital data and 1-year results from the German Aortic Valve Registry (GARY).

Eur Heart J. 2019 May 1;40(17):1323-1330. doi: 10.1093/eurheartj/ehy699.

 

Sayour AA, Korkmaz-Icöz S, Loganathan S, Ruppert M, Sayour VN, Oláh A, Benke K, Brune M, Benko R, Horváth EM, Karck M, Merkely B, Radovits T, Szabó G (2019)

Acute canagliflozin treatment protects against in vivo myocardial ischemia-reperfusion injury in non-diabetic male rats and enhances endothelium-dependent vasorelaxation.

J Transl Med. 2019 Apr 16;17(1):127. doi: 10.1186/s12967-019-1881-8.

 

Ruppert M, Bódi B, Korkmaz-Icöz S, Loganathan S, Jiang W, Lehmann L, Oláh A, Barta BA, Sayour AA, Merkely B, Karck M, Papp Z, Szabó G, Radovits T (2019)

Myofilament Ca2+ sensitivity correlates with left ventricular contractility during the progression of pressure overload-induced left ventricular myocardial hypertrophy in rats.

J Mol Cell Cardiol. 2019 Apr;129:208-218. doi: 10.1016/j.yjmcc.2019.02.017. Epub 2019 Mar 4.

 

Mkalaluh S, Szczechowicz M, Karck M, Szabo G (2019)

Twenty-year results of surgical pulmonary thromboembolectomy in acute pulmonary embolism.

Scand Cardiovasc J. 2019 Apr;53(2):98-103. doi: 10.1080/14017431.2019.1600013. Epub 2019 Apr 16.

 

Korkmaz-Icöz S, Li S, Hüttner R, Ruppert M, Radovits T, Loganathan S, Sayour AA, Brlecic P, Lasitschka F, Karck M, Szabó G (2019)

Hypothermic perfusion of donor heart with a preservation solution supplemented by mesenchymal stem cells.

J Heart Lung Transplant. 2019 Mar;38(3):315-326. doi: 10.1016/j.healun.2018.12.003. Epub 2018 Dec 6.

 

Moreno C, Mueller S, Szabo G (2019)

Non-invasive diagnosis and biomarkers in alcohol-related liver disease.

J Hepatol. 2019 Feb;70(2):273-283. doi: 10.1016/j.jhep.2018.11.025. Review.

 

Ruppert M, Korkmaz-Icöz S, Li S, Brlecic P, Németh BT, Oláh A, Horváth EM, Veres G, Pleger S, Grabe N, Merkely B, Karck M, Radovits T, Szabó G (2019)

Comparison of the Reverse-Remodeling Effect of Pharmacological Soluble Guanylate Cyclase Activation With Pressure Unloading in Pathological Myocardial Left Ventricular Hypertrophy.

Front Physiol. 2019 Jan 8;9:1869. doi: 10.3389/fphys.2018.01869. eCollection 2018.

 

Kremer J, Al-Maisary SSA, Szabó G (2019)

A Clean Cut: Minimally Invasive Mitral Valve Replacement after Heart Transplantation.

Thorac Cardiovasc Surg Rep. 2019 Jan;8(1):e27-e29. doi: 10.1055/s-0039-1693451. Epub 2019 Aug 21.

 

2018

Korkmaz-Icöz S, Li S, Loganathan S, Radovits T, Ruppert M, Brlecic P, Sayour AA, Veres G, Fleming T, Brune M, Most P, Karck M, Szabó G (2018)

Impairment of the Akt pathway in transplanted Type 1 diabetic hearts is associated with post-transplant graft injury.

Interact Cardiovasc Thorac Surg. 2018 Dec 1;27(6):884-894. doi: 10.1093/icvts/ivy188.

 

Korkmaz-Icöz S, Brlecic P, Ruppert M, Radovits T, Karck M, Szabó G (2018)

Mechanical pressure unloading therapy reverses thoracic aortic structural and functional changes in a hypertensive rat model.

J Hypertens. 2018 Dec;36(12):2350-2361. doi: 10.1097/HJH.0000000000001853.

 

Mkalaluh S, Szczechowicz M, Dib B, Weymann A, Szabo G, Karck M (2018)

Open surgical thoracoabdominal aortic aneurysm repair: The Heidelberg experience.

J Thorac Cardiovasc Surg. 2018 Dec;156(6):2067-2073. doi: 10.1016/j.jtcvs.2018.05.081. Epub 2018 Jun 6.

 

Schnuelle P, Benck U, Krämer BK, Yard BA, Zuckermann A, Wagner F, Szabo G, Borggrefe M, Karck M, Gummert J (2018)

Impact of Donor Core Body Temperature on Graft Survival After Heart Transplantation.

Transplantation. 2018 Nov;102(11):1891-1900. doi: 10.1097/TP.0000000000002337.

 

Veres G, Schmidt H, Hegedus P, Korkmaz-Icöz S, Radovits T, Loganathan S, Brlecic P, Li S, Karck M, Szabó G (2018)

Is internal thoracic artery resistant to reperfusion injury? Evaluation of the storage of free internal thoracic artery grafts.

J Thorac Cardiovasc Surg. 2018 Oct;156(4):1460-1469. doi: 10.1016/j.jtcvs.2018.05.079. Epub 2018 Jun 8.

 

Ruppert M, Korkmaz-Icöz S, Loganathan S, Jiang W, Lehmann L, Oláh A, Sayour AA, Barta BA, Merkely B, Karck M, Radovits T, Szabó G (2018)

Pressure-volume analysis reveals characteristic sex-related differences in cardiac function in a rat model of aortic banding-induced myocardial hypertrophy.

Am J Physiol Heart Circ Physiol. 2018 Sep 1;315(3):H502-H511. doi: 10.1152/ajpheart.00202.2018. Epub 2018 May 25.

 

Aliabadi-Zuckermann AZ, Gökler J, Kaider A, Riebandt J, Moayedifar R, Osorio E, Haberl T, Angleitner P, Laufer G, Forsythe J, Knezevic I, Skoric B, Erasmus M, van Cleemput J, Caliskan K, De Jonge N, Szabolcs Z, Prodán Z, Wasler A, Bara C, Udovicic M, Sandhaus T, Garbade J, Ruhparwar A, Schoenrath F, Hirt S, Antretter H, Schulz U, Richter M, Thul J, Barten MJ, Haneya A, Aleksic I, Eifert S, Berchtold-Herz M, Smits J, Zuckermann AO (2018)

Donor heart selection and outcomes: An analysis of over 2,000 cases.

J Heart Lung Transplant. 2018 Aug;37(8):976-984. doi: 10.1016/j.healun.2018.04.014. Epub 2018 Apr 30.

 

Veres G, Hagenhoff M, Schmidt H, Radovits T, Loganathan S, Bai Y, Korkmaz-Icöz S, Brlecic P, Sayour AA, Karck M, Szabó G (2018)

Targeting Phosphodiesterase-5 by Vardenafil Improves Vascular Graft Function.

Eur J Vasc Endovasc Surg. 2018 Aug;56(2):256-263. doi: 10.1016/j.ejvs.2018.03.025. Epub 2018 May 1.

 

Mkalaluh S, Szczechowicz M, Dib B, Sabashnikov A, Szabo G, Karck M, Weymann A (2018)

Early and long-term results of minimally invasive mitral valve surgery through a right mini-thoracotomy approach: a retrospective propensity-score matched analysis.

PeerJ. 2018 May 28;6:e4810. doi: 10.7717/peerj.4810. eCollection 2018.

 

Korkmaz-Icöz S, Radovits T, Szabó G (2018)

Targeting phosphodiesterase 5 as a therapeutic option against myocardial ischaemia/reperfusion injury and for treating heart failure.

Br J Pharmacol. 2018 Jan;175(2):223-231. doi: 10.1111/bph.13749. Epub 2017 Mar 23.

 

Korkmaz-Icöz S, Szczesny B, Marcatti M, Li S, Ruppert M, Lasitschka F, Loganathan S, Szabó C, Szabó G (2018)

Olaparib protects cardiomyocytes against oxidative stress and improves graft contractility during the early phase after heart transplantation in rats.

Br J Pharmacol. 2018 Jan;175(2):246-261. doi: 10.1111/bph.13983. Epub 2017 Oct 2.

 


2017

Geis N, Raake P, Mereles D, Chorianopoulos E, Szabo G, Katus HA, Bekeredjian R, Pleger ST (2017)

Percutaneous repair of severe mitral valve regurgitation secondary to chordae rupture in octogenarians using MitraClip.

J Interv Cardiol. 2017 Oct 12. doi: 10.1111/joic.12455. [Epub ahead of print]

 

Mkalaluh S, Szczechowicz M, Dib B, Szabo G, Karck M, Weymann A (2017)

Outcomes and Predictors of Mortality After Mitral Valve Surgery in High-Risk Elderly Patients: The Heidelberg Experience.

Med Sci Monit. 2017 Dec 31;23:6193-6200.

 

Farag M, Badowski D, Koschny R, Skopp G, Brcic A, Szabo GB (2017)

Extracorporeal life support and digoxin-specific Fab fragments for successful management of Taxus baccata intoxication with low output and ventricular arrhythmia.

Am J Emerg Med. 2017 Dec;35(12):1987.e3-1987.e7. doi: 10.1016/j.ajem.2017.09.031. Epub 2017 Sep 18.

 

Benke K, Mátyás C, Sayour AA, Oláh A, Németh BT, Ruppert M, Szabó G, Kökény G, Horváth EM, Hartyánszky I, Szabolcs Z, Merkely B, Radovits T (2017)

Pharmacological preconditioning with gemfibrozil preserves cardiac function after heart transplantation..

Sci Rep. 2017 Oct 27;7(1):14232. doi: 10.1038/s41598-017-14587-3.

 

Czirok S, Fang L, Radovits T, Szabó G, Szénási G, Rosivall L, Merkely B, Kökény G (2017)

Cinaciguat ameliorates glomerular damage by reducing ERK1/2 activity and TGF-ß expression in type-1 diabetic rats.

Sci Rep. 2017 Sep 11;7(1):11218. doi: 10.1038/s41598-017-10125-3.

 

Li S, Korkmaz-Icöz S, Radovits T, Ruppert M, Spindler R, Loganathan S, Hegedűs P, Brlecic P, Theisinger B, Theisinger S, Höger S, Brune M, Lasitscha F, Karck M, Yard B, Szabó G (2017)

Donor preconditioning after the onset of brain death with dopamine derivate n-octanoyl dopamine improves early posttransplant graft function in the rat.

Am J Transplant. 2017 Jul;17(7):1802-1812. doi: 10.1111/ajt.14207. Epub 2017 Feb 28.

 

Ruppert M, Korkmaz-Icöz S, Li S, Merkely B, Karck M, Radovits T, Szabó G (2017)

Reverse electrical remodeling following pressure unloading in a rat model of hypertension-induced left ventricular myocardial hypertrophy.

Hypertens Res. 2017 Jul;40(7):637-645. doi: 10.1038/hr.2017.1. Epub 2017 Jan 26.

 

Farag M, Borst T, Sabashnikov A, Zeriouh M, Schmack B, Arif R, Beller CJ, Popov AF, Kallenbach K, Ruhparwar A, Dohmen PM, Szabó G, Karck M, Weymann A (2017)

Surgery for Infective Endocarditis: Outcomes and Predictors of Mortality in 360 Consecutive Patients.

Med Sci Monit. 2017 Jul 25;23:3617-3626.

 

Schmidt C, Wiedmann F, Zhou XB, Heijman J, Voigt N, Ratte A, Lang S, Kallenberger SM, Campana C, Weymann A, De Simone R, Szabo G, Ruhparwar A, Kallenbach K, Karck M, Ehrlich JR, Baczkó I, Borggrefe M, Ravens U, Dobrev D, Katus HA, Thomas D (2017)

Inverse remodelling of K2P3.1 K+ channel expression and action potential duration in left ventricular dysfunction and atrial fibrillation: implications for patient-specific antiarrhythmic drug therapy.

Eur Heart J. 2017 Jun 7;38(22):1764-1774. doi: 10.1093/eurheartj/ehw559.

 

Seppelt PC, Brcic A, Karck M, Szabó G (2017)

Removal of a giant left ventricular thrombus after myocardial infarction due to dissection of left anterior descending artery.

Interact Cardiovasc Thorac Surg. 2017 Jun 1;24(6):964-966. doi: 10.1093/icvts/ivx020.

 

Bäcker H, Polgár L, Soós P, Lajkó E, Láng O, Merkely B, Szabó G, Dohmen PM, Weymann A, Kohidai L (2017)

Impedimetric Analysis of the Effect of Decellularized Porcine Heart Scaffold on Human Fibrosarcoma, Endothelial, and Cardiomyocyte Cell Lines.

Med Sci Monit. 2017 May 11;23:2232-2240.

 

Mátyás C, Németh BT, Oláh A, Török M, Ruppert M, Kellermayer D, Barta BA, Szabó G, Kökény G, Horváth EM, Bódi B, Papp Z, Merkely B, Radovits T (2016)

Prevention of the development of heart failure with preserved ejection fraction by the phosphodiesterase-5A inhibitor vardenafil in rats with type 2 diabetes.

Eur J Heart Fail. 2017 Mar;19(3):326-336. doi: 10.1002/ejhf.711. Epub 2016 Dec 19.

 

Benke K, Sayour AA, Mátyás C, Ágg B, Németh BT, Oláh A, Ruppert M, Hartyánszky I, Szabolcs Z, Radovits T, Merkely B, Szabó G (2016)

Heterotopic Abdominal Rat Heart Transplantation as a Model to Investigate Volume Dependency of Myocardial Remodeling.

Transplantation. 2017 Mar;101(3):498-505. doi: 10.1097/TP.0000000000001585.

 

Farag M, Arif R, Sabashnikov A, Zeriouh M, Popov AF, Ruhparwar A, Schmack B, Dohmen PM, Szabó G, Karck M, Weymann A (2017)

Repair or Replacement for Isolated Tricuspid Valve Pathology? Insights from a Surgical Analysis on Long-Term Survival.

Med Sci Monit. 2017 Feb 25;23:1017-1025.

 

Farag M, Patil NP, Sabashnikov A, Arif R, Szabó G, Kallenbach K, Ruhparwar A, Karck M, Brenner T, Hofer S, Weymann A (2017)

Comparison of Two Miniaturized Cardiopulmonary Bypass Systems Regarding Inflammatory Response.

Artif Organs. 2017 Feb;41(2):139-145. doi: 10.1111/aor.12750. Epub 2016 Sep 22

 


2016

Arif R, Farag M, Zaradzki M, Reissfelder C, Pianka F, Bruckner T, Kremer J, Franz M, Ruhparwar A, Szabo G, Beller CJ, Karck M, Kallenbach K, Weymann A (2016)

Ischemic Colitis after Cardiac Surgery: Can We Foresee the Threat?

PLoS ONE 11(12): e0167601. doi:10.1371/ journal.pone.0167601

 

Kremer J, Muschitz GK, Aumayr K, Moser P, Szabo G, Weymann A, Zuckermann A, Podesser BK (2016)

Influence of antithymocyte globulin treatment of brain dead organ donor on inflammatory response in cardiac grafts: an experimental study in mice.

Transpl Int. 2016 Dec;29(12):1329-1336. doi: 10.1111/tri.12851. Epub 2016 Sep 30.

 

Németh BT, Mátyás C, Oláh A, Lux Á, Hidi L, Ruppert M, Kellermayer D, Kökény G, Szabó G, Merkely B, Radovits T (2016)

Cinaciguat prevents the development of pathologic hypertrophy in a rat model of left ventricular pressure overload.

Sci Rep. 2016 Nov 17;6:37166. doi: 10.1038/srep37166

 

Korkmaz-Icöz S, Lehner A, Li S, Vater A, Radovits T, Brune M, Ruppert M, Sun X, Brlecic P, Zorn M, Karck M, Szabó G (2016)

Left ventricular pressure-volume measurements and myocardial gene expression profile in type 2 diabetic Goto-Kakizaki rats.

Am J Physiol Heart Circ Physiol. 2016 Oct 1;311(4):H958-H971. doi: 10.1152/ajpheart.00956.2015. Epub 2016 Aug 12

 

Ruppert M, Korkmaz-Icöz S, Li S, Németh BT, Hegedüs P, Brlecic P, Mátyás C, Zorn M, Merkely B, Karck M, Radovits T, Szabó G (2016)

Myocardial reverse remodeling after pressure unloading is associated with maintained cardiac mechanoenergetics in a rat model of left ventricular hypertrophy.

Am J Physiol Heart Circ Physiol. 2016 Sep 1;311(3):H592-603. doi: 10.1152/ajpheart.00085.2016. Epub 2016 Jun 24

 

Korkmaz-Icöz S, Al Said S, Radovits T, Li S, Brune M, Hegedűs P, Atmanli A, Ruppert M, Brlecic P, Lehmann LH, Lahrmann B, Grabe N, Yoshikawa Y, Yasui H, Most P, Karck M, Szabó G (2016)

Oral treatment with a zinc complex of acetylsalicylic acid prevents diabetic cardiomyopathy in a rat model of type-2 diabetes: activation of the Akt pathway.

Cardiovasc Diabetol. 2016 May 6;15(1):75. doi: 10.1186/s12933-016-0383-8.

 

Hirschberg K, Wiedmann F, Zitron E, Fortner P, Riffel JH, Chorianopoulos E, Gdynia G, Mechtersheimer G, Andrassy M, Szabó G, Arif R, Katus HA, Buss SJ (2016)

Incidental finding of a giant intracardiac angioma infiltrating both ventricles in a 35-year-old woman: a case report.

J Med Case Rep. 2016 Apr 12;10(1):94. doi: 10.1186/s13256-016-0860-4.

 

Schmidt C, Wiedmann F, Voigt N, Zhou XB, Heijman J, Lang S, Albert V, Kallenberger S, Ruhparwar A, Szabó G, Kallenbach K, Karck M, Borggrefe M, Biliczki P, Ehrlich JR, Baczkó I, Lugenbiel P, Schweizer PA, Donner BC, Katus HA, Dobrev D, Thomas D (2016)

Response to Letter Regarding Article, "Upregulation of K2P3.1 K+ Current Causes Action Potential Shortening in Patients With Chronic Atrial Fibrillation".

Circulation. 2016 Mar 15;133(11):e440-1. doi: 10.1161/CIRCULATIONAHA.115.020662.

 

Korkmaz-Icöz S, Atmanli A, Radovits T, Li S, Hegedüs P, Ruppert M, Brlecic P, Yoshikawa Y, Yasui H, Karck M, Szabó G (2015)

Administration of zinc complex of acetylsalicylic acid after the onset of myocardial injury protects the heart by upregulation of antioxidant enzymes.

J Physiol Sci. 2016 Mar;66(2):113-25. doi: 10.1007/s12576-015-0403-6. Epub 2015 Oct 23.

 

Arif R, Farag M, Gertner V, Szabó G, Weymann A, Veres G, Ruhparwar A, Bekeredjian R, Bruckner T, Karck M, Kallenbach K, Beller CJ (2016)

Female Gender and Differences in Outcome after Isolated Coronary Artery Bypass Graft Surgery: Does Age Play a Role?

PLoS One. 2016 Feb 4;11(2):e0145371. doi: 10.1371/journal.pone.0145371. eCollection 2016.

 

Hegedűs P, Li S, Korkmaz-Icöz S, Radovits T, Mayer T, Al Said S, Brlecic P, Karck M, Merkely B, Szabó G (2016)

Dimethyloxalylglycine treatment of brain-dead donor rats improves both donor and graft left ventricular function after heart transplantation.

J Heart Lung Transplant. 2016 Jan;35(1):99-107. doi: 10.1016/j.healun.2015.06.016. Epub 2015 Jul 4.

 

Veres G, Hegedűs P, Barnucz E, Schmidt H, Radovits T, Zöller R, Karck M, Szabó G (2016)

TiProtec preserves endothelial function in a rat model.

J Surg Res. 2016 Jan;200(1):346-55. doi: 10.1016/j.jss.2015.06.062. Epub 2015 Jul 2.

 


2015

Schmack B, Szabo G, Karck M, Weymann A (2015)

Tissue Engineering von Atrioventrikularklappen.

Z Herz-Thorax-Gefäßchir. December 2015, Volume 29, Issue 6, pp 402–409; DOI: 10. 1007/s00398-015-0028-3

 

Li S, Korkmaz-Icöz S, Radovits T, Hegedűs P, Karck M, Szabó G (2015)

Comparison of donor hearts from hypoxic cardiac arrest followed by warm ischemia and from exsanguination as non-beating donor models in rat heart transplantation.

J Cardiothorac Surg. 2015 Dec 16;10 Suppl 1:A196. doi: 10.1186/1749-8090-10-S1-A196. Epub 2015 Dec 16

 

Veres G, Hegedues P, Schmidt H, Radovits T, Zöller R, Karck M, Szabó G (2015)

Tiprotec preserves endothelial function after cold ischemia and warm reperfusion: comparison between Saline, Custodiol and Tiprotec.

J Cardiothorac Surg. 2015 Dec 16;10 Suppl 1:A74. doi: 10.1186/1749-8090-10-S1-A74. Epub 2015 Dec 16

 

Szabo G, Weymann A, Schmack B, Badowski-Zyla D, Veres G, Wagner F, Rastan A, Doenst T, Karck M (2015)

Custodiol-N versus Custodiol: a prospective randomized double blind multicenter phase III Trial.

J Cardiothorac Surg. 2015 Dec 16;10 Suppl 1:A73. doi: 10.1186/1749-8090-10-S1-A73. Epub 2015 Dec 16.

 

Weymann A, Patil NP, Sabashnikov A, Korkmaz S, Li S, Soos P, Ishtok R, Chaimow N, Pätzold I, Czerny N, Schmack B, Popov AF, Simon AR, Karck M, Szabo G (2015)

Perfusion-Decellularization of Porcine Lung and Trachea for Respiratory Bioengineering.

Artif Organs. 2015 Dec;39(12):1024-32. doi: 10.1111/aor.12481. Epub 2015 Apr 20

 

Korkmaz-Icöz S, Vater A, Li S, Lehner A, Radovits T, Hegedus P, Ruppert M, Brlecic P, Zorn M, Karck M, Szabó G (2015)

Mild type 2 diabetes mellitus improves remote endothelial dysfunction after acute myocardial infarction.

J Diabetes Complications. 2015 Nov-Dec;29(8):1253-60. doi: 10.1016/j.jdiacomp.2015.06.012. Epub 2015 Jul 2

 

Mátyás C, Németh BT, Oláh A, Hidi L, Birtalan E, Kellermayer D, Ruppert M, Korkmaz-Icöz S, Kökény G, Horváth EM, Szabó G, Merkely B, Radovits T (2015)

The soluble guanylate cyclase activator cinaciguat prevents cardiac dysfunction in a rat model of type-1 diabetes mellitus.

Cardiovasc Diabetol. 2015 Oct 31;14(1):145. doi: 10.1186/s12933-015-0309-x.

 

Korkmaz-Icöz S, Atmanli A, Radovits T, Li S, Hegedüs P, Ruppert M, Brlecic P, Yoshikawa Y, Yasui H, Karck M, Szabó G (2015)

Administration of zinc complex of acetylsalicylic acid after the onset of myocardial injury protects the heart by upregulation of antioxidant enzymes.

J Physiol Sci. 2015 Oct 23. [Epub ahead of print]

 

Loganathan S, Korkmaz-Icöz S, Radovits T, Li S, Mikles B, Barnucz E, Hirschberg K, Karck M, Szabó G (2015)

Effects of soluble guanylate cyclase activation on heart transplantation in a rat model.

J Heart Lung Transplant. 2015 Oct;34(10):1346-53. doi: 10.1016/j.healun.2015.05.006. Epub 2015 Jun 11

 

Korkmaz S, Atmanli A, Li S, Radovits T, Hegedus P, Barnucz E, Hirschberg K, Loganathan S, Yoshikawa Y, Yasui H, Karck M, Szabó G (2015)

Superiority of zinc complex of acetylsalicylic acid to acetylsalicylic acid in preventing postischemic myocardial dysfunction.

Exp Biol Med (Maywood). 2015 Sep;240(9):1247-55. doi: 10.1177/1535370215570184. Epub 2015 Feb 9

 

Schmidt C, Wiedmann F, Voigt N, Zhou XB, Heijman J, Lang S, Albert V, Kallenberger S, Ruhparwar A, Szabó G, Kallenbach K, Karck M, Borggrefe M, Biliczki P, Ehrlich JR, Baczkó I, Lugenbiel P, Schweizer PA, Donner BC, Katus HA, Dobrev D, Thomas D (2015)

Upregulation of K2P3.1 K+ Current Causes Action Potential Shortening in Patients with Chronic Atrial Fibrillation.

Circulation. 2015 Jul 14;132(2):82-92. doi: 10.1161/CIRCULATIONAHA.114.012657. Epub 2015 May 7

 

Veres G, Hegedus P, Barnucz E, Schmidt H Radovits T, Zöller R, Karck M, Szabó G (2015)

TiProtec preserves endothelial function in a rat model.

J Surg Res. 2015 Jul 2. pii: S0022-4804(15)00740-4. doi: 10.1016/j.jss.2015.06.062. [Epub ahead of print]

 

Korkmaz-Icöz S, Lehner A, Li S, Vater A, Radovits T, Hegedus P, Ruppert M, Brlecic P, Zorn M, Karck M, Szabó G (2015)

Mild Type 2 Diabetes Mellitus Reduces the Susceptibility of the Heart to Ischemia/Reperfusion Injury: Identification of Underlying Gene Expression Changes.

J Diabetes Res. 2015;2015:396414. Epub 2015 Jul 1

 

Li S, Loganathan S, Korkmaz S, Radovits T, Hegedűs P, Zhou Y, Karck M, Szabó G (2015)

Transplantation of donor hearts after circulatory or brain death in a rat model.

J Surg Res. 2015 May 1;195(1):315-24. doi: 10.1016/j.jss.2014.12.038. Epub 2014 Dec 24

 

Veres G, Hegedűs P, Barnucz E, Zöller R, Klein S, Radovits T, Korkmaz S, Karck M, Szabó G (2015)

Graft preservation with heparinized blood/saline solution induces severe graft dysfunction.

Interact Cardiovasc Thorac Surg. 2015 May;20(5):594-600. doi: 10.1093/icvts/ivv010. Epub 2015 Feb 11.

 

Veres G, Hegedűs P, Barnucz E, Zöller R, Klein S, Schmidt H, Radovits T, Korkmaz S, Karck M, Szabó G (2015)

Endothelial Dysfunction of Bypass Graft: Direct Comparison of In Vitro and In Vivo Models of Ischemia-Reperfusion Injury.

PLoS One. 2015 Apr 15;10(4):e0124025. doi: 10.1371/journal.pone.0124025. eCollection 2015

 

Lehmann HI, Richter D, Prokesch H, Graeff C, Prall M, Simoniello P, Fournier C, Bauer J, Kaderka R, Weymann A, Szabó G, Sonnenberg K, Constantinescu A, Johnson SB, Misiri J, Takami M, Miller RC, Herman MG, Asirvatham SJ, Brons S, Jäkel O, Haberer T, Debus J, Durante M, Bert C, Packer DL (2015)

AV Node Ablation in Langendorff-Perfused Porcine Hearts Using Carbon Ion Particle Therapy: Methods and an In vivo Feasibility Investigation for Catheter-Free Ablation of Cardiac Arrhythmias.

Circ Arrhythm Electrophysiol. 2015 Apr;8(2):429-38. doi: 10.1161/CIRCEP.114.002436. Epub 2015 Jan 21

 

Prall M, Lehmann HI, Prokesch H, Richter D, Graeff C, Kaderka R, Sonnenberg K, Hauswald H, Weymann A, Bauer J, Constantinescu A, Haberer T, Debus J, Szabó G, Korkmaz S, Durante M, Packer DL, Bert C (2015)

Treatment of arrhythmias by external charged particle beams: a Langendorff feasibility study.

Biomed Tech (Berl). 2015 Apr 1;60(2):147-56. doi: 10.1515/bmt-2014-0101.

 

Weymann A, Radovits T, Karck M, Szabo G (2015)

Auswirkung des totalen Aortenbogenersatzes auf die ventrikuloarterielle Kopplung.

Z Herz-Thorax-Gefäßchir, 2015 Apr;29(2):133-138

 

Oláh A, Németh BT, Mátyás C, Horváth EM, Hidi L, Birtalan E, Kellermayer D, Ruppert M, Merkely G, Szabó G, Merkely B, Radovits T (2015)

Cardiac effects of acute exhaustive exercise in a rat model.

Int J Cardiol. 2015 Mar 1;182:258-66. doi: 10.1016/j.ijcard.2014.12.045. Epub 2014 Dec 23.

 

Li S, Korkmaz S, Loganathan S, Radovits T, Hegedűs P, Karck M, Szabó G (2015)

Short- and long-term effects of brain death on post-transplant graft function in a rodent model.

Interact Cardiovasc Thorac Surg. 2015 Mar;20(3):379-86. doi: 10.1093/icvts/ivu403. Epub 2014 Dec 11

 

Veres G, Radovits T, Merkely B, Karck M, Szabó G (2015)

Custodiol-N, the novel cardioplegic solution reduces ischemia/reperfusion injury after cardiopulmonary bypass.

J Cardiothorac Surg. 2015 Feb 28;10(1):27

 

Radovits T, Korkmaz S, Mátyás C, Oláh A, Németh BT, Páli S, Hirschberg K, Zubarevich A, Gwanmesia PN, Li S, Loganathan S, Barnucz E, Merkely B, Szabó G (2015)

An altered pattern of myocardial histopathological and molecular changes underlies the different characteristics of type-1 and type-2 diabetic cardiac dysfunction.

J Diabetes Res. 2015;2015:728741. doi: 10.1155/2015/728741. Epub 2015 Jan 5.

 

Lehmann HI, Richter D, Prokesch H, Graeff C, Prall M, Simoniello P, Fournier C, Bauer J, Kaderka R, Weymann A, Szabó G, Sonnenberg K, Constantinescu A, Johnson SB, Misiri J, Takami M, Miller RC, Herman MG, Asirvatham SJ, Brons S, Jäkel O, Haberer T, Debus J, Durante M, Bert C, Packer DL (2015)

AV Node Ablation in Langendorff-Perfused Porcine Hearts Using Carbon Ion Particle Therapy: Methods and an In vivo Feasibility Investigation for Catheter-Free Ablation of Cardiac Arrhythmias.

Circ Arrhythm Electrophysiol. 2015 Jan 21. pii: CIRCEP.114.002436. [Epub ahead of print]

 


2014

Hegedűs P, Korkmaz S, Radovits T, Schmidt H, Li S, Yoshikawa Y, Yasui H, Merkely B, Karck M, Szabó G (2014)

Bis (Aspirinato) Zinc (II) Complex Successfully Inhibits Carotid Arterial Neointima Formation after Balloon-injury in Rats.

Cardiovasc Drugs Ther. 2014 Dec;28(6):533-9. doi: 10.1007/s10557-014-6549-2

 

Ruhparwar A, Piontek P, Ungerer M, Ghodsizad A, Partovi S, Foroughi J, Szabo G, Farag M, Karck M, Spinks GM, Kim SJ (2014)

Electrically Contractile Polymers Augment Right Ventricular Output in the Heart.

Artif Organs. 2014 Dec;38(12):1034-9. doi: 10.1111/aor.12300. Epub 2014 Apr 1

 

Oláh A, Németh BT, Mátyás C, Horváth EM, Hidi L, Birtalan E, Kellermayer D, Ruppert M, Merkely G, Szabó G, Merkely B, Radovits T (2014)

Cardiac effects of acute exhaustive exercise in a rat model.

Int J Cardiol. 2014 Dec 23;182C:258-266. doi: 10.1016/j.ijcard.2014.12.045. [Epub ahead of print]

 

Li S, Korkmaz S, Loganathan S, Radovits T, Hegedüs P, Karck M, Szabó G (2014)

Short-term and long-term effects of brain death on posttransplant graft function in a rodent model.

Interact Cardiovasc Thorac Surg. 2014 Dec 11. pii: ivu403. [Epub ahead of print]

 

Radovits T*, Korkmaz S*, Mátyás C, Oláh A, Németh BT, Páli S, Hirschberg K, Zubarevich A, Neh Gwanmesia P, Li S, Loganathan S, Barnucz E, Merkely B, Szabó G (2014)

An altered pattern of myocardial histopathological and molecular changes underlies the different characteristics of type-1 and type-2 diabetic cardiac dysfunction.

Journal of Diabetes Research 2014 [accepted for puplication]

 

Weymann A, Patil NP, Sabashnikov A, Jungebluth P, Korkmaz S, Li S, Veres G, Soos P, Ishtok R, Chaimow N, Pätzold I, Czerny N, Schies C, Schmack B, Popov AF, Simon AR, Karck M, Szabo G (2014)

Bioartificial Heart: a human-sized porcine model - the way ahead.

PLoS One. 2014 Nov 3; 9(11): e111591. doi:10.1371/journal.pone.0111591

 

Weymann A*, Radovits T*, Schmack B, Korkmaz S, Li S, Chaimow N, Pätzold I, Becher PM, Hartyanszky I, Soos P, Merkely G, Nemeth BT, Istok R, Veres G, Merkely B, Terytze K, Karck M, Szabo G (2014)

Total aortic arch replacement: Superior ventriculo-arterial coupling with decellularized allografts compared with conventional prostheses.

PLoS One. 2014 Jul 31;9(7):e103588. doi: 10.1371/journal.pone.0103588. eCollection 2014.

 

Nemeth B, Hidi L, Toth R, Veres G, Olah A, Matyas C, Merkely G, Merkely B, Szabo G, Radovits T (2014)

P229Tranexamic acid and aprotinin: antifibrinolytics in cardiac surgery.

Cardiovasc Res. 2014 Jul 15;103 Suppl 1:S41. doi: 10.1093/cvr/cvu082.162. Epub 2014 Jun 27

 

Matyas C, Olah A, Nemeth B, Hidi L, Birtalan E, Ruppert M, Kokeny G, Szabo G, Merkely B, Radovits T (2014)

P758Cinaciguat prevents diabetes mellitus related cardiac alterations in rats.

Cardiovasc Res. 2014 Jul 15;103 Suppl 1:S139. doi: 10.1093/cvr/cvu098.177. Epub 2014 Jun 27

 

Matyas C, Korkmaz S, Olah A, Nemeth B, Hidi L, Birtalan E, Torok M, Merkely B, Szabo G, Radovits T (2014)

P765Diabetic cardiomyopathy: a comparative investigation in diabetic rat models.

Cardiovasc Res. 2014 Jul 15;103 Suppl 1:S140. doi: 10.1093/cvr/cvu098.184. Epub 2014 Jun 27

 

Weymann A, Radovits T, Schmack B, Li S, Korkmaz S, Soós P, Istók R, Veres G, Chaimow N, Karck M, Szabó G (2014)

In Vitro Generation of Atrioventricular Heart Valve Neoscaffolds.

Artif Organs. 2014 Jul;38(7):E118-28. doi: 10.1111/aor.12321. Epub 2014 May 20.

 

Weymann A, Schmack B, Rauch H, Rosendal C, Karck M, Szabó G (2014)

Entanglement of a circular mapping catheter in the mitral valve with persistent iatrogenic atrial septal defect after attempted pulmonary vein isolation: a word of caution.

Ann Thorac Cardiovasc Surg. 2014 Jun 21;20(3):250-2. Epub 2012 Dec 26.

 

Fischer F, Vonderlin N, Seyler C, Zitron E, Korkmaz S, Szabó G, Thomas D, Katus HA, Scholz EP (2014)

Isoenzyme-specific regulation of cardiac Kv1.5/Kvβ1.2 ion channel complex by protein kinase C: central role of PKCβII.

Naunyn Schmiedebergs Arch Pharmacol. 2014 May;387(5):469-76. doi: 10.1007/s00210-014-0965-5. Epub 2014 Feb 28

 

Weymann A, Borst T, Popov AF, Sabashnikov A, Bowles C, Schmack B, Veres G, Chaimow N, Simon AR, Karck M, Szabo G (2014)

Surgical treatment of infective endocarditis in active intravenous drug users: A justified procedure?

J Cardiothorac Surg. 2014 Mar 24;9(1):58. doi: 10.1186/1749-8090-9-58.

 

Heye T, Kauczor HU, Szabo G, Hosch W (2013)

Computed tomography angiography of coronary artery bypass grafts: robustness in emergency and clinical routine settings.

Acta Radiol. 2014 Mar 1;55(2):161-70. doi: 10.1177/0284185113494977. Epub 2013 Aug 1

 

Farag M, Weymann A, Schmack B, Rauch H, Karck M, Szabo G (2014)

Massive Calcified Tricuspid Valve Endocarditis in a Patient with Dual Lumen Tunneled Venous Catheter.

Ann Thorac Cardiovasc Surg. 2014;20 Suppl:730-3. doi: 10.5761/atcs.cr.13.02275. Epub 2013 Jun 26.

 


2013

Szabó G, Schmack B, Bulut C, Soós P, Weymann A, Stadtfeld S, Karck M (2013)

Constrictive pericarditis: risks, aetiologies and outcomes after total pericardiectomy: 24 years of experience.

Eur J Cardiothorac Surg. 2013 Dec;44(6):1023-8. doi: 10.1093/ejcts/ezt138. Epub 2013 Jun 12.

 

Korkmaz S, Bährle-Szabó S, Loganathan S, Li S, Karck M, Szabó G (2013)

Marginal donors: can older donor hearts tolerate prolonged cold ischemic storage?

Aging Clin Exp Res. 2013 Oct;25(5):597-600. doi: 10.1007/s40520-013-0131-9. Epub 2013 Aug 15.

 

Radovits T, Oláh A, Lux A, Németh BT, Hidi L, Birtalan E, Kellermayer D, Mátyás C, Szabó G, Merkely B (2013)

Rat model of exercise-induced cardiac hypertrophy - hemodynamic characterization using left ventricular pressure-volume analysis.

Am J Physiol Heart Circ Physiol. 2013 Jul 1;305(1):H124-34. doi: 10.1152/ajpheart.00108.2013. Epub 2013 May 3.

 

Radovits T, Arif R, Bömicke T, Korkmaz S, Barnucz E, Karck M, Merkely B, Szabó G (2013)

Vascular dysfunction induced by hypochlorite is improved by the selective phosphodiesterase-5-inhibitor vardenafil .

Eur J Pharmacol. 2013 Jun 15;710(1-3):110-9. doi: 10.1016/j.ejphar.2013.04.012. Epub 2013 Apr 23

 

Veres G, Hegedüs P, Barnucz E, Zöller R, Radovits T, Korkmaz S, Kolonics F, Weymann A, Karck M, Szabo G. (2013)

Addition of Vardenafil into Storage Solution Protects the Endothelium in a Hypoxia-Reoxygenation Model.

Eur J Vasc Endovasc Surg. 2013 Aug;46(2):242-8. doi: 10.1016/j.ejvs.2013.05.006. Epub 2013 Jun 7.

 

Fang L, Radovits T, Szabó G, Mózes MM, Rosivall L, Kökény G (2013)

Selective PDE-5 inhibitor vardenafil ameliorates renal damage in type-1 diabetic rats by restoring cGMP level in podocytes.

Nephrol Dial Transplant. 2013 Jul;28(7):1751-61. doi: 10.1093/ndt/gfs391. Epub 2012 Nov 29.

 

Hirschberg K, Tarcea V, Páli S, Barnucz E, Gwanmesia PN, Korkmaz S, Radovits T, Loganathan S, Merkely B, Karck M, Szabó G (2013)

Cinaciguat prevents neointima formation after arterial injury by decreasing vascular smooth muscle cell migration and proliferation.

Int J Cardiol. 2013 Jul 31;167(2):470-7. doi: 10.1016/j.ijcard.2012.01.032. Epub 2012 Feb 20.

 

Korkmaz S, Zitron E, Bangert A, Seyler C, Li S, Hegedüs P, Scherer D, Li J, Fink T, Schweizer PA, Giannitsis E, Karck M, Szabó G, Katus HA, Kaya Z (2013)

Provocation of an autoimmune response to cardiac voltage-gated sodium channel NaV1.5 induces cardiac conduction defects in rats.

J Am Coll Cardiol. 2013 Jul 23;62(4):340-9. doi: 10.1016/j.jacc.2013.04.041. Epub 2013 May 15.

 

Korkmaz S, Barnucz E, Li S, Radovits T, Hegedüs P, Zubarevich A, Hirschberg K, Weymann A, Puskás LG, Ózsvári B, Faragó N, Kanisai I, Fábián G, Gyuris M, Merkely B, Karck M, Szabó S, Szabó G (2013)

Q50, an iron-chelating and zinc-complexing agent, improves cardiac function in rat models of ischemia/reperfusion-induced myocardial injury.

Circ J. 2013;77(7):1817-26. Epub 2013 Apr 11.

 

Barnucz E, Veres G, Hegedus P, Klein S, Zoller R, Radovits T, Korkmaz S, Horkay F, Merkely B, Karck M, Szabo G (2013)

Prolyl-hydroxylase inhibition preserves endothelial cell function in a rat model of vascular ischemia reperfusion injury.

J Pharmacol Exp Ther. 2013 Apr;345(1):25-31. doi: 10.1124/jpet.112.200790. Epub 2013 Feb 6

 

Weymann A, Schmack B, Rosendal C, Karck M, Szabo G (2013).

Surgical Management of Subaortic Stenosis.

Ann Thorac Cardiovasc Surg. 2013;19(5):390-3. Epub 2012 Nov 30.

 

Korkmaz S, Loganathan S, Mikles B, Radovits T, Barnucz E, Hirschberg K, Li S, Hegedüs P, Páli S, Weymann A, Karck M, Szabó G (2013)

Nitric Oxide- and Heme-Independent Activation of Soluble Guanylate Cyclase Attenuates Peroxynitrite-Induced Endothelial Dysfunction in Rat Aorta.

J Cardiovasc Pharmacol Ther. 2013 Jan;18(1):70-7. doi: 10.1177/1074248412455696. Epub 2012 Aug 22.

 

Weymann A, Schmack B, Okada T, Soos P, Istok R, Radovits T, Straub B, Barnucz E, Loganathan S, Paetzold I, Chaimow N, Schies C, Korkmaz S, Tochtermann U, Karck M, Szabo G (2013)

Reendothelialization of Human Heart Valve Neoscaffolds Using Umbilical Cord Derived Endothelial Cells.

Circ J. 2013;77(1):207-16. Epub 2012 Sep 21.

 


2012

Wolfe J, Szabo G, Radovits T, Waite L (2012)

Using a mathematical model for diastolic filling through the mitral valve to determine cardiac properties.

Biomed Sci Instrum 2012; 48: 493-500.

 

Fang L, Radovits T, Szabó G, Mózes MM, Rosivall L, Kökény G (2012)

Selective PDE-5 inhibitor vardenafil ameliorates renal damage in type-1 diabetic rats by restoring cGMP level in podocytes.

Nephrol Dial Transplant. 2012 Nov 29. [Epub ahead of print]

 

Radovits T, Mátyás C, Oláh A, Kökény G, Barnucz E, Szabó G, Merkely B (2012)

Effects of the phosphodiesterase-5 inhibitor vardenafil on diabetic cardiovascular dysfunction.

Cardiologia Hungarica 2012; 42: 272-9

 

Szabó G (2012)

Hearts from the deep freezer? Novel concept to increase safe cardiac preservation times.

Transplantation. 2012 Sep 15;94(5):449. doi: 10.1097/TP.0b013e3182637097.

 

Li S, Korkmaz S, Loganathan S, Weymann A, Radovits T, Barnucz E, Hirschberg K, Hegedüs P, Zhou Y, Tao L, Pali S, Veres G, Karck M, Szabo G (2012)

Acute Ethanol Exposure Increases the Susceptibility of the Donor Hearts to Ischemia/Reperfusion Injury after Transplantation in Rats.

PLoS One. 2012;7(11):e49237. doi: 10.1371/journal.pone.0049237. Epub 2012 Nov 14.

 

Weymann A, Schmack B, Rosendal C, Karck M, Szabo G (2012)

Thromboembolus crossing patent foramen ovale: appearance in multislice computed tomography and echocardiography.

Ann Thorac Cardiovasc Surg. 2012;18(3):256-8.

 

Bokesch PM, Szabo G, Wojdyga R, Grocott HP, Smith PK, Mazer CD, Vetticaden S, Wheeler A, Levy JH (2012)

A phase 2 prospective, randomized, double-blind trial comparing the effects of tranexamic acid with ecallantide on blood loss from high-risk cardiac surgery with cardiopulmonary bypass (CONSERV-2 Trial).

J Thorac Cardiovasc Surg. 2012 May;143(5):1022-9. Epub 2011 Jul 2

 

Weymann A, Schmack B, Karck M, Szabo G (2012)

Orthotopic Heart Transplantation in a Patient with Persistent Left Superior Vena Cava.

Ann Thorac Cardiovasc Surg. 2012 Dec 20;18(6):554-6. Epub 2012 Apr 27.

 

Radovits T, Beller CJ, Groves JT, Merkely B, Karck M, Szabó C, Szabó G (2012)

Effects of FP15, a peroxynitrite decomposition catalyst on cardiac and pulmonary function after cardiopulmonary bypass.

Eur J Cardiothorac Surg. 2012 Feb;41(2):391-6

 

Weymann A, Schmack B, Rosendal C, Rauch H, Karck M, Tochtermann U, Szabo G (2012)

Tricuspid Valve Endocarditis with Septic Pulmonary Emboli in a Drug Addict.

Ann Thorac Cardiovasc Surg. 2012;18(5):481-4. Epub 2012 Mar 24.

 

Szabó G, Loganathan S, Merkely B, Groves JT, Karck M, Szabó C, Radovits T (2012)

Catalytic peroxynitrite decomposition improves reperfusion injury after heart transplantation.

J Thorac Cardiovasc Surg. 2012 Jun;143(6):1443-9. Epub 2012 Mar 7.

 

Hirschberg K, Tarcea V, Páli S, Barnucz E, Gwanmesia PN, Korkmaz S, Radovits T, Loganathan S, Merkely B, Karck M, Szabó G (2012)

Cinaciguat prevents neointima formation after arterial injury by decreasing vascular smooth muscle cell migration and proliferation.

Int J Cardiol. 2012 Feb 20. [Epub ahead of print]

 

Rosendal C, Hien MD, Bruckner T, Martin EO, Szabo G, Rauch H (2012)

Left ventricular outflow tract: intraoperative measurement and changes caused by mitral valve surgery.

J Am Soc Echocardiogr. 2012 Feb;25(2):166-72. Epub 2011 Nov 10.

 

Loganathan S, Radovits T, Korkmaz S, Hirschberg K, Barnucz E, Weymann A, Bömicke T, Arif R, Karck M, Szabó G (2012)

Enhancement of Myocardial and Vascular Function after Phosphodiesterase-5 Inhibition in a Rat Model.

Thorac Cardiovasc Surg. 2012 Jun;60(4):247-54. Epub 2012 Jan 17.

 


2011

Soos P, Schmack B, Weymann A, Veres G, Merkely B, Karck M, Szabó G (2011)

Perioperative risk factors for serious gastrointestinal complications treated by laparotomy after cardiac surgery using cardiopulmonary bypass.

Crit Care. 2011;15 (Suppl 1 31st International Symposium on Intensive Care and Emergency Medicinehttp://ccforum.com/supplements/notes/ccv15s1-info.pdf):P6

 

Hirschberg K, Radovits T, Páli Sz, Barnucz E, Szabó G, Merkely B (2011)

Neointimal hyperplasia induced by carotid endarterectomy is reduced by superoxide-dismutase mimetic treatment in rats.

Cardiologia Hungarica 2011; 41: 325-3

 

Erbel C, Achenbach J, Akhavanpoor M, Dengler TJ, Lasitschka F, Gleissner CA, Bea F, Katus HA, Szabo G (2011)

PARP inhibition in atherosclerosis and its effects on dendritic cells, T cells and auto-antibody levels.

Eur J Med Res. 2011 Aug 8;16(8):367-74.

 

Soos P, Schmack B, Istok R, Polgar L, Bagyura Z, Veres G, Merkely B, Szabo G, Weymann A (2011)

Whole Heart Tissue Engineering.

Cardiologia Hungarica 2011; 41: 43-48.

 

Weymann A, Schmack B, Szabo G (2011)

Pathophysiological Consequences of Brain Death.

Tx Med 23: 140-145.

 

Weymann A, Szabo G (2011)

Images in clinical medicine. Lung herniation after minimally invasive cardiothoracic surgery.

N Engl J Med 2011; 365(9): e19

 

Weymann A, Schmack B, Karck M, Szabo G (2011)

Giant Pseudoaneurysm of the Ascending Aorta Caused by Chronic Stanford Type A Aortic Dissection.

Can J Cardiol. 2011 Nov;27(6):871.e3-4.

 

Waite L, Veres G, Fine J, Szabo G (2011)

A computer model of early diastolic filling through the mitral valve.

Proc. IMechE Part H: J. Engineering in Medicine 2011, Vol. 225(3), 255-267

 

Radovits T, Szabó G, Merkely B (2011)

Ageing-associated changes in cardiovascular structure and function in apparent health (review)

Interv Med Appl Sci 2011 Vol. 3 (1), pp. 27–31

 

Szabó G, Seres L, Soós P, Gorenflo M, Merkely B, Horkay F, Karck M, Radovits T (2011)

Tetrahydrobiopterin improves cardiac and pulmonary function after cardiopulmonary bypass.

Eur J Cardiothorac Surg. 2011 Sep;40(3):695-700. Epub 2011 Feb 15

 

Sax B, Nádasy Gy, Túri K, Hirschberg K, Fürjész D, Nagy A, Merkely B, Szabó G, Monos E, Kékesi V (2011)

Coronary Vasoconstrictor Effect of Ghrelin Is Not Mediated By Growth Hormone Secretagogue Receptor 1a Type In Dogs.

Peptides. 2011 Feb;32(2):362-7. Epub 2010 Nov 30

 

Weymann A, Loganathan S, Takahashi H, Schies C, Claus B, Hirschberg K, Soós P, Korkmaz S, Schmack B, Karck M, Szabó G (2011)

Development and Evaluation of a Perfusion Decellularization Porcine Heart Model: Generation of Three-Dimensional Myocardial Neoscaffolds.

Circ J. 2011 Mar 25;75(4):852-60. Epub 2011 Feb 2

 

Radovits T, Korkmaz S, Miesel-Gröschel C, Seidel B, Stasch JP, Merkely B, Karck M, Szabó G (2011)

Pre-conditioning with the soluble guanylate cyclase activator Cinaciguat reduces ischaemia-reperfusion injury after cardiopulmonary bypass.

Eur J Cardiothorac Surg. 2011 Feb;39(2):248-55. Epub 2010 Jun 29.

 

Szabó G, Veres G, Radovits T, Gerő D, Modis K, Miesel-Gröschel C, Horkay F, Karck M, Szabó C (2011)

Cardioprotective effects of hydrogen sulfide.

Nitric Oxide. 2011 Aug 1;25(2):201-10. Epub 2010 Nov 19.

 


2010

Veres G, Radovits T, Seres L, Horkay F, Karck M, Szabó G (2010)

Effects of inosine on reperfusion injury after cardiopulmonary bypass.

J Cardiothorac Surg. 2010 Nov 8;5:106.

 

Schmack B, Weymann A, Soos P, Karck M, Szabo G (2010)

Custodiol-N, a novel organ protection solution protects against myocardial and endothelial reperfusion injury after orthotopic heart transplantation.

Proceedings 15th World Congress on Heart Disease

 

Loganathan S, Radovits T, Hirschberg K, Korkmaz S, Koch A, Karck M, Szabó G (2010)

Effects of Custodiol-N, a Novel Organ Preservation Solution, on Ischemia/Reperfusion Injury.

J Thorac Cardiovasc Surg. 2010 Apr;139(4):1048-56. Epub 2009 Nov 27

 

Veres G, Radovits T, Otila G, Hirschberg K, Haider H, Krieger N, Knoll A, Weigang E, Szabolcs Z, Karck M, Szabó G (2010):

Efficacy of the non-adenosine analogue A1 adenosine receptor agonist (BR-4935) on cardiovascular function after cardiopulmonary bypass.

Thorac Cardiovasc Surg. 2010 Mar;58(2):86-92. Epub 2010 Mar 23.

 

Hirschberg K, Radovits T, Korkmaz S, Loganathan S, Zöllner S, Seidel B, Páli Sz, Barnucz E, Merkely B, Karck M, Szabó G (2010)

Combined superoxide dismutase mimetic and peroxynitrite scavenger protects against neointima formation after endarterectomy in association with decreased proliferation and nitro-oxidative stress.

Eur J Vasc Endovasc Surg. 2010 Aug;40(2):168-75

 

Szabó G, Veres G, Radovits T, Haider H, Krieger N, Bährle S, Niklisch S, Miesel-Gröschel C, van de Locht A, Karck M (2010):

The novel synthetic serine protease inhibitor CU-2010 dose-dependently reduces postoperative blood loss and improves postischemic recovery after cardiac surgery in a canine model.

J Thorac Cardiovasc Surg. 2010 Mar;139(3):732-740

 

Koch A, Loganathan S, Radovits T, Sack FU, Karck M, Szabó GB (2010):

Deferoxamine, the newly developed iron chelator LK-614 and N-alpha-acetyl-histidine in myocardial protection.

Interact Cardiovasc Thorac Surg. 2010 Feb;10(2):181-4. Epub 2009 Nov 13.

 

Szabó G, Veres G, Radovits T, Haider H, Krieger N, Bährle S, Miesel-Gröschel C, Niklisch S, Karck M, van de Locht A (2010):

Effects of novel synthetic serine protease inhibitors on postoperative blood loss, coagulation parameters, and vascular relaxation after cardiac surgery.

J Thorac Cardiovasc Surg. 2010 Jan;139(1):181-8; discussion 188

 


2009

Neeb D, Kunz RP, Ley S, Szábo G, Strauss LG, Kauczor HU, Kreitner KF, Schreiber LM (2009):

Quantification of pulmonary blood flow (PBF): validation of perfusion MRI and nonlinear contrast agent (CA) dose correction with H(2)15O positron emission tomography (PET).

Magn Reson Med. 2009 Aug;62(2):476-87

 

Szabó G (2009):

A glass of red wine to improve mitochondrial biogenesis? Novel mechanisms of resveratrol.

Am J Physiol Heart Circ Physiol. 2009 Jul;297(1):H8-9. Epub 2009 May 22

 

Koch A, Radovits T, Loganathan S, Sack FU, Karck M, Szabó GB (2009):

Myocardial protection with the use of L-arginine and N-alpha-acetyl-histidine.

Transplant Proc. 2009 Jul-Aug;41(6):2592-4

 

Korkmaz S, Radovits T, Barnucz E, Hirschberg K, Neugebauer P, Loganathan S, Veres G, Pali S, Seidel B, Zöllner S, Karck M, Szabo G (2009):

Pharmacological activation of soluble guanylate cyclase protects the heart against ischemic injury.

Circulation. 2009 Aug 25;120(8):677-86. Epub 2009 Aug 10

 

Korkmaz S, Radovits T, Barnucz E, Neugebauer P, Arif R, Hirschberg K, Loganathan S, Seidel B, Karck M, Szabó G (2009):

Dose-dependent effects of a selective phosphodiesterase-5-inhibitor on endothelial dysfunction induced by peroxynitrite in rat aorta.

Eur J Pharmacol. 2009 Aug 1;615(1-3):155-62. Epub 2009 May 29

 

Radovits T, Korkmaz S, Loganathan S, Barnucz E, Bömicke T, Arif R, Karck M, Szabó G (2009):

Comparative investigation of the left ventricular pressure-volume relationship in rat models of type 1 and type 2 diabetes mellitus.

Am J Physiol Heart Circ Physiol. 2009 Jul;297(1):H125-33. Epub 2009 May 8

 

Hirschberg K, Entz L, Szabó G, Merkely B (2009):

 

Restenosis following endovascular interventions: clinical and experimental studies.

Orv Hetil. 2009 Jul 12;150(28):1307-12

 

Waite L, Fine J, Veres G, Szabo G (2009):

A velocity driven lumped-parameter model of mitral valve blood flow - biomed 2009.

Biomed Sci Instrum. 2009;45:401-6

 

Radovits T, Bömicke T, Kökény G, Arif R, Loganathan S, Kécsán K, Korkmaz S, Barnucz E, Sandner P, Karck M, Szabó G (2009):

The phosphodiesterase-5 inhibitor vardenafil improves cardiovascular dysfunction in experimental diabetes mellitus.

Br J Pharmacol 2009; 156 (6); 909-19

 

Szabó G, Radovits T, Veres G, Krieger N, Loganathan S, Sandner P, Karck M (2009):

Vardenafil protects against myocardial and endothelial injuries after cardiopulmonary bypass.

Eur J Cardiothorac Surg. 2009 Oct;36(4):657-64. Epub 2009 Jun 11

 

Radovits T, Zotkina J, Lin LN, Karck M, Szabó G (2009):

Endothelial dysfunction after hypoxia-reoxygenation: Do in vitro models work?

Vascul Pharmacol. 2009 Jul;51(1):37-43. Epub 2009 Feb 4

 

Hirschberg K, Gombos T, Dósa E, Somorjai A, Szilágyi Á, Szabó G, Füst G, Entz L (2009):

Association between Estrogen Receptor α Gene Polymorphisms and Early Restenosis after Eversion Carotid Endarterectomy and Carotid Stenting.

Atherosclerosis. 2009 Sep;206(1):186-92. Epub 2009 Jan 29

 

Hirschberg K, Radovits T, Loganathan S, Entz L, Beller CJ, Gross ML, Sandner P, Karck M, Szabó G (2009):

Selective phosphodiesterase-5 inhibition reduces neointimal hyperplasia in rat carotid arteries after surgical endarterectomy.

J Thorac Cardiovasc Surg. 2009 Jun;137(6):1508-14. Epub 2009 Feb 10

 


2008

Veres G, Radovits T, Szabolcs Z, Szabó G (2008)

Effect of recombinant aprotinin on postoperative blood loss and coronary vascular function in a canine model of cardiopulmonary bypass.

Cardiologia Hungarica 2008; 38: 247-53

 

Radovits T, Gerö D, Lin LN, Loganathan S, Hoppe-Tichy T, Szabó C, Karck M, Sakurai H, Szabó G (2008)

Improvement of Aging-Associated Cardiovascular Dysfunction by the Orally Administered Copper(II)-aspirinate Complex.

Rejuvenation Res. 2008 Oct;11(5):945-56

 

Ley S, Unterhinninghofen R, Ley-Zaporozhan J, Schenk JP, Kauczor HU, Szabo G (2008):

Validation of magnetic resonance phase-contrast flow measurements in the main pulmonary artery and aorta using perivascular ultrasound in a large animal model.

Invest Radiol. 2008 Jun;43(6):421-426

 

Ley-Zaporozhan J, Ley S, Unterhinninghofen R, Weinheimer O, Saito Y, Kauczor HU, Szabo G (2008):

Quantification of Lung Volume at Different Tidal Volumes and Positive End-Expiratory Pressures in a Porcine Model by Using Retrospective Respiratory Gated 4D-Computed Tomography.

Invest Radiol. 2008 Jun;43(6):461-469

 

Loganathan S, Radovits T, Hirschberg K, Korkmaz S, Barnucz E, Karck M, Szabó G (2008):

Effects of Selective Phosphodiesterase-5-Inhibition on Myocardial Contractility and Reperfusion Injury After Heart Transplantation.

Transplantation. 2008 Nov 27;86(10):1414-8

 

Puderbach M, Risse F, Biederer J, Ley-Zaporozhan J, Ley S, Szabo G, Semmler W, Kauczor HU (2008):

In vivo Gd-DTPA concentration for MR lung perfusion measurements: Assessment with computed tomography in a porcine model.

Eur Radiol. 2008 Oct;18(10):2102-7. Epub 2008 Apr 30

 

Ley-Zaporozhan J, Kreitner KF, Unterhinninghofen R, Helm E, Puderbach M, Schenk JP, Deshpande V, Krummenauer F, Szabo G, Kauczor HU, Ley S (2008):

Assessment of Thoracic Aortic Dimensions in an Experimental Setting: Comparison of Different Unenhanced Magnetic Resonance Angiography Techniques With Electrocardiogram-Gated Computed Tomography Angiography for Possible Application in the Pediatric Population.

Invest Radiol. 2008 Mar;43(3):179-186

 

Unterhinninghofen R, Ley S, Ley-Zaporozhan J, von Tengg-Kobligk H, Bock M, Kauczor HU, Szabó G, Dillmann R (2008)

Concepts for Visualization of Multidirectional Phase-contrast MRI of the Heart and Large Thoracic Vessels.

Acad Radiol. 2008 Mar;15(3):361-9

 

Radovits T, Lin LN, Zotkina J, Koch A, Rauen U, Köhler G, Karck M, Szabó G (2008)

Endothelial dysfunction after long term cold storage in HTK organ preservation solutions - effects of iron chelators and N-alpha-acetyl-L-histidine.

J Heart Lung Transplant. 2008 Feb;27(2):208-16

 


2007

Beller CJ, Horvath E, Kosse J, Becker A, Radovits T, Krempien R, Berger I, Hagl S, Szabo C, Szabo G (2007):

Opposite effects of vascular irradiation on inflammatory response and apoptosis induction in the vessel wall layers via the peroxynitrite-poly(ADP-ribose) polymerase pathway.

Clin Res Cardiol. 2007 Jan;96(1):8-16. Epub 2006 Oct 10

 

Radovits T, Gerö D, Kékesi V, Szabó C, Szabó G (2007)

The peroxynitrite decomposition catalyst FP15 improves ageing-associated cardiac and vascular dysfunction.

Cardiologia Hungarica 2007; 37:267-275

 

Radovits T, Zotkina J, Lin LN, Bömicke T, Arif R, Gero D, HorvathEM, Karck M, Szabo C, Szabo G (2007):

Poly(ADP-ribose) polymerase inhibition improves endothelial dysfunction induced by hypochlorite.

Exp Biol Med (Maywood). 2007 Oct;232(9):1204-12

 

Radovits T, Lin LN, Zotkina J, Gero D, Szabo C, Karck M, Szabo G (2007):

Poly(ADP-ribose) polymerase inhibition improves endothelial dysfunction induced by reactive oxidant hydrogen peroxide in vitro.

Eur J Pharmacol. 2007 Jun 14;564(1-3):158-66; Epub 12 Mar 2007

 

Radovits T, Seres L, Gero D, Berger I, Szabo C, Karck M, Szabo G (2007):

Single dose treatment with PARP-inhibitor INO-1001 improves aging-associated cardiac and vascular dysfunction.

Exp Gerontol. Jul; 42 (7):676-85. Epub 2007 Feb 20

 

Radovits T, Seres L, Gero D, Lin LN, Beller CJ, Chen SH, Zotkina J, Berger I, Groves JT, Szabo C, Szabo G (2007):

The peroxynitrite decomposition catalyst FP15 improves ageing-associated cardiac and vascular dysfunction.

Mech Ageing Dev. 2007 Feb;128(2):173-81. Epub 2006 Nov 20

 

Koch A, Burgschweiger A, Herpel E, Sack FU, Schirmacher P, Szabo GB, Karck M, Schnabel PA (2007):

Inducible NO synthase expression in endomyocardial biopsies after heart transplantation in relation to the postoperative course.

Eur J Cardiothorac Surg. 2007 Oct;32(4):639-43. Epub 2007 Aug 6

 

Veres G, Radovits T, Schultz H, Lin LN, Hutter J, Weigang E, Szabolcs Z, Szabo G (2007):

Effect of recombinant aprotinin on postoperative blood loss and coronary vascular function in a canine model of cardiopulmonary bypass.

Eur J Cardiothorac Surg. 2007 Aug;32(2):340-5. Epub 2007 May 17

 

Weigang E, Sircar R, von Samson P, Hartert M, Siegenthaler MP, Luehr M, Richter H, Szabo G, Czerny M, Zentner J, Beyersdorf F (2007):

Efficacy and frequency of cerebrospinal fluid drainage in operative management of thoracoabdominal aortic aneurysms.

Thorac Cardiovasc Surg. 2007 Mar;55(2):73-78

 

Weigang E, Luehr M, Harloff A, Euringer W, Etz CD, Szabo G, Beyersdorf F, Siegenthaler MP (2007):

Incidence of neurological complications following overstenting of the left subclavian artery.

Eur J Cardiothorac Surg. 2007 Apr;31(4):628-36. Epub 2007 Feb 1

 


2006

Beller CJ, Kosse J, Radovits T, Gero D, Krempien R, Gross ML, Berger I, Hagl S, Szabo C, Szabo G (2006):

Poly(ADP-ribose) polymerase inhibition combined with irradiation: A dual treatment concept to prevent neointimal hyperplasia after endarterectomy.

Int J Radiat Oncol Biol Phys. Nov 1;66(3):867-75

 

Beller CJ, Kosse J, Radovits T, Krempien R, Gross ML, Berger I, Hagl S, Szabo G(2006):

Adjunct brachytherapy: a new concept to prevent intimal hyperplasia after surgical endarterectomy?

Eur J Cardiothorac Surg Mar;29(3):334-342

 

Beller CJ, Radovits T, Kosse J, Gero D, Szabo C, Szabo G(2006):

Activation of the peroxynitrite-poly(adenosine diphosphate-ribose) polymerase pathway during neointima proliferation: a new target to prevent restenosis after endarterectomy.

J Vasc Surg; Apr 43(4): 824-830.

 

Beller CJ, Radovits T, Seres L, Kosse J, Krempien R, Gross ML, Penzel R, Berger I, Huber PE, Hagl S, Szabo C, Szabo G (2006):

Poly(ADP-ribose) polymerase inhibition reverses vascular dysfunction after gamma-irradiation.

Int J Radiat Oncol Biol Phys Aug 1;65(5):1528-35

 

Ley S, Ley-Zaporozhan J, Unterhinninghofen R, Saito Y, Fabel-Schulte M, Weinheimer O, Schenk JP, Szabo G, Kauczor HU (2006):

Investigation of retrospective respiratory gating techniques for acquisition of thin-slice 4d-multidetector-computed tomorgraphy (mdct) of the lung: feasibility study in a large animal model.

Exp Lung Res Oct;32(9):395-412

 

Szabo G, Bahrle S, Sivanandam V, Stumpf N, Gero D, Berger I, Beller C, Hagl S, Szabo C, Dengler TJ (2006):

Immunomodulatory effects of poly(ADP-ribose) polymerase inhibition contribute to improved cardiac function and survival during acute cardiac rejection.

J Heart Lung Transplant Jul;25(7):794-804.

 

Szabo G, Bahrle S, Stumpf N, Szabo C, Hagl S (2006):

Contractile dysfunction in experimental cardiac allograft rejection: role of the poly (ADP-ribose) polymerase pathway.

Transpl Int Jun;19(6):506-13.

 

Szabo G, Soos P, Heger U, Mandera S, Buhmann V, Bahrle S, Kohl B, Hagl S (2006):

l-Arginine Improves Endothelial and Myocardial Function after Brain Death.

Transplantation Jul 15;82(1):108-12.

 

Szabo G, Soos P, Bahrle S, Radovits T, Weigang E, Kekesi V, Merkely B, Hagl S (2006):

Adaptation of the right ventricle to an increased afterload in the chronically volume overloaded heart.

Ann Thorac Surg. Sep;82(3):989-95; discussion 995

 

Szabo G, Stumpf N, Radovits T, Sonnenberg K, Gero D, Hagl S, Szabo C, Bahrle S (2006):

Effects of inosine on reperfusion injury after heart transplantation.

Eur J Cardiothorac Surg Jul;30(1):96-102. Epub 2006 May 26.

 

Weigang E, Hartert M, Siegenthaler MP, Beckmann NA, Sircar R, Szabo G, Etz CD, Luehr M, von Samson P, Beyersdorf F (2006)

Perioperative management to improve neurologic outcome in thoracic or thoracoabdominal aortic stent-grafting.

Ann Thorac Surg. 2006 Nov;82(5):1679-1687 Comment in:

Ann Thorac Surg. 2006 Nov;82(5):1687

 

Weigang E, Ghanem N, Chang XC, Richter H, Frydrychowicz A, Szabo G, Dudeck O, Knirsch W, von Samson P, Langer M, Beyersdorf F (2006)

Evaluation of three different measurement methods for dural ectasia in Marfan syndrome.

Clin Radiol. 2006 Nov;61(11):971-8

 

Zaporozhan J, Ley S, Unterhinninghofen R, Saito Y, Fabel-Schulte M, Keller S, Szabo G, Kauczor HU (2006):

Free-Breathing Three-Dimensional Computed Tomography of the Lung Using Prospective Respiratory Gating: Charge-Coupled Device Camera and Laser Sensor Device in an Animal Experiment.

 

Invest Radiol; May; 41(5): 468-475.

 


2005

Andrasi TB, Bielik H, Blazovics A, Zima E, Vago H, Szabo G, Juhasz-Nagy A(2005):

Mesenteric vascular dysfunction after cardiopulmonary bypass with cardiac arrest is aggravated by coexistent heart failure.

Shock; 23(4): 324-329

 

Andrasi TB, Blazovics A, Szabo G, Vahl CF, Hagl S (2005):

Poly(ADP-ribose) polymerase inhibitor PJ-34 reduces the mesenteric vascular injury induced by experimental cardiopulmonary bypass with cardiac arrest.

Am J Physiol Heart Circ Physiol. 2005 Jun;288(6):H2972-8. Epub 2005 Jan 28.

 

Beller CJ, Labrosse MR, Thubrikar MJ, Szabo G, Robicsek F, Hagl S (2005):

Are there surgical implications to aortic root motion?

J Heart Valve Dis Sep;14(5):610-5

 

Beller CJ, Labrosse MR, Thubrikar MJ, Szabo G, Robicsek F, Hagl S (2005):

Increased aortic wall stress in aortic insufficiency: clinical data and computer model.

Eur J Cardiothorac Surg; Feb. 27(2): 270-275

 

Pleger ST, Remppis A, Heidt B, Volkers M, Chuprun JK, Kuhn M, Zhou RH, Gao E, Szabo G, Weichenhan D, Muller OJ, Eckhart AD, Katus HA, Koch WJ, Most P (2005)

S100A1 Gene Therapy Preserves in Vivo Cardiac Function after Myocardial Infarction.

Mol Ther Dec;12(6):1120-9 

 

Szabo G, Bahrle S (2005)

Contractility-afterload mismatch after the Fontan operation.

Cardiol Young Dec;15 Suppl 3:35-8. 

 

Szabo G, Bahrle S (2005)

Role of nitrosative stress and poly(ADP-ribose) polymerase activation in myocardial reperfusion injury.

Curr Vasc Pharmacol Jul;3(3):215-20. 

 

Szabo G, Soos P, Heger U, Flechtenmacher C, Bahrle S, Zsengeller Z, Szabo C, Hagl S (2005):

Poly(ADP-ribose) polymerase inhibition attenuates biventricular reperfusion injury after orthotopic heart transplantation.

Eur J Cardiothorac Surg; Feb; 27(2): 226-234.

 


2004

Beller CJ, Krempien R, Günther F, Steinitz A, Unterhinninghofen R, Szabó G, Harms W, Hagl S (2004):

Virtual dosimetry: a new tool for computer-aided coronary artery reconstruction with intraoperative irradiation.

Biomed Tech 2004;49(2):106-107

 

Soos P, Andrasi T, Buhmann V, Kohl B, Vahl C, Hagl S, Szabo G (2004):

Myocardial protection after systemic application of L-arginine during reperfusion.

J Cardiovasc Pharmacol 43(6): 782-8

 

Szabó G, Soós P, Seres L, Beller CJ, Juhász-Nagy A (2004):

Computer assisted ventricular reduction surgery.

Biomed Tech 2004;49(2):524-525

 

Szabo G (2004):

Physiologic changes after brain death.

J Heart Lung Transplant 23(9 Suppl): S223-6.

 

Szabo G, Hagl S (2004):

Effects of timing of l-arginine supplementation after deep hypothermic storage and reperfusion.

J Heart Lung Transplant 23(7):918-21

 

Szabo G, Liaudet L, Hagl S, Szabo C (2004):

Poly(ADP-ribose) polymerase activation in the reperfused myocardium.

Cardiovasc Res. Feb 15;61(3): 471-480. 

 

Szabo G, Seres L, Soos P, Flechtenmacher C, Zsengeller Z, Sack FU, Szabo C, Hagl S (2004):

Poly-ADP-ribose polymerase inhibition reduces mesenteric injury after

cardiopulmonary bypass.

Thorac Cardiovasc Surg; Dec; 52(6): 338-343

 

Szabo G, Soans D, Graf A, Beller CJ, Waite L, Hagl S (2004):

A new computer model of mitral valve hemodynamics during ventricular filling.

Eur J Cardio-Thorac Surg 26: 239-247

 

Szabo G, Soos P, Mandera S, Heger U, Flechtenmacher C, Bahrle S, Seres L, Cziraki A, Gries A, Zsengeller Z, Vahl CF, Hagl S, Szabo C (2004):

INO-1001 a novel poly-(ADP-ribose) polymerase (PARP) inhibitor improves cardiac and pulmonary function after crystalloid cardioplegia and extracorporal circulation.

Shock May;21(5): 426-432.

 

Szabo G, Soos P, Mandera S, Heger U, Flechtenmacher C, Seres L, Zsengeller Z, Sack FU, Szabo C, Hagl S (2004):

Mesenteric injury after cardiopulmonary bypass: role of poly(adenosine 5'-diphosphate-ribose) polymerase.

Crit Care Med; Dec; 32(12): 2392-2397

 

Szabo G, Soos P, Bahrle S, Zsengeller Z, Flechtenmacher C, Hagl S, Szabo C (2004):

Role of poly(ADP-ribose) polymerase activation in the pathogenesis of cardiopulmonary dysfunction in a canine model of cardiopulmonary bypass.

Eur J Cardiothorac Surg May;25(5): 825-832

 


2003

Andrási TB, Soós P, Bakos G, Stumpf N, Blazovics A, Hagl S, Szabó G (2003):

l-arginine protects the mesenteric vascular circulation against cardiopulmonary bypass-induced vascular dysfunction.

Surgery 134(1): 72-79 

 

 

Gries A, Herr A, Kirsch S, Gunther C, Weber S, Szabo G, Holzmann A, Bottiger BW, Martin E (2005)

Inhaled nitric oxide inhibits platelet-leukocyte interactions in patients with acute respiratory distress syndrome.

Crit Care Med Jun;31(6):1697-704. 

 

 

Hackert T, Kienle P, Weitz J, Werner J, Szabo G, Hagl S, Buchler MW, Schmidt J (2003):

Accuracy of diagnostic laparoscopy for early diagnosis of abdominal complications after cardiac surgery.

Surg Endosc Aug 15 Vol.17(7)

 

Liaudet L, Szabó G, Szabó C (2003):

Oxydative stress and regional ischemia-reperfusion injury: the peroxynitrite-poly(ADP-ribose) polmerase connection.

Coronary Artery Dis. 2003;14:115-122

 

Szabo G, Buhmann V, Andrasi T, Stumpf N, Bahrle S, Kekesi V, Hagl S, Szabo C, Juhasz-Nagy A (2003):

Poly-ADP-ribose polymerase inhibition protects against myocardial and endothelial reperfusion injury after hypothermic cardiac arrest.

J Thorac Cardiovasc Surg 126(3):651-658. 

 

 

Szabo G, Buhmann V, Graf A, Melnitschuk S, Bahrle S, Vahl CF, Hagl S (2003):

Ventricular energetics after the Fontan operation: Contractility-afterload mismatch.

J Thorac Cardiovasc Surg 125: 1061-1069

 


2002

Andrási TB, Buhmann V, Soós P, Juhasz-Nagy A, Szabó G (2002): 

Mesenteric complications after hypothermic cardiopulmonary bypass with cardiac arrest: underlying mechanisms. 

Artif Organs 26(11):943-946 

 

Andrási TB, Kekesi V, Blazovics A, Dobi I, Szabó G, Juhasz-Nagy A (2002): 

ETA receptor blockade protects the small intestine against ischaemia/reperfusion injury in dogs via an enhancement of antioxidant defences. 

Clin Sci (Lond) 103 Suppl 1: 59S-63S 

 

Soans D, Szabo G, Bolind C, Waite L (2002)

A variable valve area, lumped parameter model of left ventricular filling.

Biomed Sci Instrum. 2002;38:483-8

 

Buhmann V, Hackert T, Sebening C, Szabó G, Vahl CF, Hagl S (2002): 

Hämodynamische Instabilität nach Hirntod I: Auswirkungen der veränderlichen Nachlast. 

Z Herz-, Thorax-, Gefäßchir 16: 79-85 

 

Buhmann V, Hackert T, Sebening C, Vahl CF, Hagl S, Szabó G (2002): 

Hämodynamische Instabilität nach Hirntod II: Koronarzirkulation und Endothelfunktion. 

Z Herz-, Thorax-, Gefäßchir 16: 86-91 

 

Szabo G, Bahrle S, Braun M, Stumpf N, Vahl CF, Hagl S (2002): 

Modulation of catecholamine responsiveness and beta-adrenergic receptor/adenylyl cyclase pathway during cardiac allograft rejection. 

Transplantation 73:535-40 

 

Szabó G, Bahrle S, Stumpf N, Sonnenberg K, Szabó EE, Pacher P, Csont T, Schulz R, Dengler TJ, Liaudet L, Jagtap PG, Southan GJ, Vahl CF, Hagl S, Szabó C (2002): 

Poly(ADP-Ribose) Polymerase Inhibition Reduces Reperfusion Injury After Heart Transplantation. 

Circ Res 90: 100-6 

 

Szabo G, Buhmann V, Bahrle S, Vahl CF, Hagl S (2002): 

Brain death impairs coronary endothelial function. 

Transplantation 73: 1846-8 

 

Szabó G, Buhmann V, Graf A, Melnitchuk S, Hagl S, Vahl CF (2002): 

Perfusion-contractility matching during fontan circulation 

Biomedizinische Technik, 47, Ergänzungsband 1, Teil 2: 912-914 

 


2001

Szabó G, Bahrle S, Fazekas L, Vahl CF, Hagl S (2001): 

The role of endothelin-B receptors in myocardial and endothelial reperfusion injury after heart transplantation. 

Thorac Cardiovasc Surg 49: 167-71

 

 

Szabó G, Bátkai S, Dengler TJ, Bahrle S, Stumpf N, Nottmeyer W, Zimmermann R, Vahl CF, Hagl S (2001): 

Systolic and diastolic properties and myocardial blood flow in the heterotopically transplanted rat heart during acute cardiac rejection. 

World J Surg 25: 545-552. 

 

 

Szabó G, Buhmann V, Vahl CF, Sebening C, Hagl S (2001): 

Endothelial function after brain death. 

J Heart Lung Transplant 20: 153 

 

 

Szabó G, Hackert T, Buhmann V, Graf A, Sebening C, Vahl CF, Hagl S (2001): 

Downregulation of myocardial contractility via intact ventriculo-

-arterial coupling in the brain dead organ donor. 

Eur J Cardiothorac Surg 20: 170-6 

 

 

Szabó G, Kiencke U, Hagl S, Vahl CF (2001): 

Veno-atrio-ventrikuläre Kopplung: Modellierung der Mitralklappenfunktion. 

Proceedings: Rechner- und sensorgestüzte Chirurgie: 315-322 

 


2000

Sebening C, Jakob H, Lange R, Vahl CF, Bodegom P, Szabó G, Fleischer F, Schmidt K, Zilow E, Springer W, Ulmer HE, Hagl S (2000): 

Vascular tracheobronchial compression syndromes. Experience in surgical treatment and literature review. 

Thorac Cardiovasc Surg 48: 164-174 

 

Szabó G, Hackert T, Buhmann V, Sebening C, Vahl CF, Hagl S (2000): 

Myocardial performance after brain death: studies in isolated hearts. 

Ann Transplant 5: 45-50 

 

Szabó G, Hackert T, Sebening C, Melnitchuk S, Vahl CF, Hagl S (2000): 

Role of neural and humoral factors in hyperdynamic reaction and cardiac dysfunction following brain death. 

J Heart Lung Transplant 19: 683-693 

 

Waite L, Schulz S, Szabo G, Vahl CF (2000)

A lumped parameter model of left ventricular filling-pressure waveforms.

Biomed Sci Instrum. 2000;36:75-80

 


1999

Szabó G, Sebening C, Hackert T, Hoffmann L, Sonnenberg K, Hagl C, Tochtermann U, Vahl CF, Hagl S (1999): 

Influence of brain death and cardiac preservation on systolic and diastolic function and coronary circulation in the cross-circulated canine heart. 

World J Surg 23: 36-43 

 

Szabó G, Hackert T, Sebening C, Hagl C, Vahl CF, Hagl S (1999): 

Modulation of coronary perfusion pressure can reverse cardiac dysfunction after brain death. 

Ann Thorac Surg 67: 18-26 

 

Dengler TJ, Szabo G, Sido B, Nottmeyer W, Zimmerman R, Vahl CF, Hünig T, Meuer SC (1999)

Prolonged allograft survival but no tolerance induction by modulating CD28 antibody JJ319 after high-responder rat heart transplantation.

Transplantation. 1999 Feb 15;67(3):392-8

 


1998

Vahl CF, Albers J, Makabe MH, Meinzer HP, Ilg M, Fu X, Szabo G, Mühling J, Hagl S (1998)

Heterogeneity of myocardial edema in isolated pig hearts after perfusion with different types of cardioprotective solutions.

Thorac Cardiovasc Surg. 1998 Oct;46(5):285-92

 

Szabó G, Bahrle S, Bátkai S, Stumpf N, Dengler TJ, Zimmermann R, Vahl CF, Hagl S (1998):

L-arginine: effect on reperfusion injury after heart transplantation

World J Surg. 1998 Aug; 22(8): 791-7; discussion 797-8 

 

Bahrle S, Szabó G, Dengler TJ, Zimmermann R, Hagl S, Kubler W (1998): 

Immunosuppressive effects of ursodeoxycholic acid in heart-allografted rats 

Transplant Proc. 1998 May; 30(3): 864-5 

 

Dengler TJ, Szabó G, Amann K, Nottmeyer W, Vahl C, Hagl S, Zimmermann R (1998): 

Induction therapy with an immunomodulatory CD2 antibody does not inhibit allograft vasculopathy after rat heart transplantation 

Transplant Proc. 1998 May; 30(3): 868-70 

 

Szabó G, Bahrle S, Fazekas L, MacDonald D, Stumpf N, Vahl CF, Hagl S (1998) 

Endothelin-A receptor antagonist BQ123 protects against myocardial

and endothelial reperfusion injury 

Thorac Cardiovasc Surg 46: 232-236 

 

Szabó G, Fazekas L, Bahrle S, MacDonald D, Stumpf N, Vahl CF, Hagl S (1998) 

Endothelin-A and -B antagonist protect myocardial and endothelial function after ischemia/reperfusion in rat heart transplantation model 

Cardiovasc Res 39: 683-690 

 

Szabó G, Sebening C, Hackert T, Hagl C, Tochtermann U, Vahl CF, Hagl S (1998) 

Effects of brain death on myocardial function and ischemic tolerance of potential donor hearts. 

J Heart Lung Transplant 17: 921-930 

 

Szabó G, Sebening C, Hackert T, Hoffmann L, Melnitchuk S, Vahl CF, Hagl S (1998) 

The role of coronary perfusion changes in cardiac dysfunction associated with brain death. 

Thorac Cardiovasc Surg 46: 339-43. 

 

Bährle S, Szabó G, Stiehl A, Theilmann L, Dengler TJ, Zimmermann R, Kübler W (1998)

Adjuvant treatment with ursodeoxycholic acid may reduce the incidence of acute cardiac allograft rejection.

J Heart Lung Transplant. 1998 Jun;17(6):592-8

 

Szabó G, Sebening C, Hagl C, Tochtermann U, Vahl CF, Hagl S (1998):

Right ventricular function after brain death: response to an increased afterload

Eur J Cardiothorac Surg. 1998 Apr; 13(4): 449-58; discussion 458-9 

 

Szabó G, Bátkai S, Bahrle S, Dengler TJ, Vahl CF, Zimmermann R, Hagl S (1998):

Effects of nitric oxide synthesis on reperfusion injury and catecholamine responsiveness in a heterotopic rat heart-transplantation model

J Cardiovasc Pharmacol. 1998 Feb; 31(2): 221-30 

 


1997

Hagl C, Szabó G, Sebening C, Tochtermann U, Vahl CF, Sonnenberg K, Hagl S (1997):

Is the brain death related endocrine dysfunction an indication for hormonal substitution therapy in the early period ?

Eur J Med Res. 1997 Oct 30; 2(10): 437-40 

 

Szabó G, Bahrle S, Dengler TJ, Batkai S, Vahl CF, Hagl S (1997):

[Reducing perfusion damage after heart transplantation with the nitric oxide donor L-arginine]

Langenbecks Arch Chir Suppl Kongressbd. 1997; 114: 7-10 

 


1996

Szabó G, Bátkai S, Bahrle S, Dengler TJ, Zimmermann R, Vahl CF, Hagl S (1996): 

The role of endogenous nitric oxide synthesis during reperfusion after reversible hypothermic ischemia. 

Fiziologia 6: 24-28 

 

Szabó G, Hackert T, Sebening C, Hagl C, Tochtermann U, Vahl CF, Hagl S (1996): 

Ex vivo blood perfusion restores cardiac function after brain death. 

Fiziologia 6: 4-8 

 


1995

Sebening C, Hagl C, Szabó G, Tochtermann U, Strobel G, Schnabel P, Amann K, Vahl CF, Hagl S (1995)

Cardiocirculatory effects of acutely increased intracranial pressure and subsequent brain death

Eur J Cardiothorac Surg. 1995; 9(7): 360-72 

 


1994

Sebening C, Hagl C, Szabó G, Tochtermann U, Vahl CF, Hagl S (1994): 

Hat die akute Erhöhung des intracraniellen Drucks - und der darauffolgende Hirntod per se - eine entscheidende Beeinträchtigung der Herzfunktion zur Folge?. 

Langenbecks Arch Chir 379: 151-155