AG Pietschmann

Selected Articles &  Selected Reviews

Dreux,M., Pietschmann,T., Granier,C., Voisset,C., Ricard-Blum,S., Mangeot,P.E., Keck,Z., Foung,S., Vu-Dac,N., Dubuisson,J., Bartenschlager,R., Lavillette,D., Cosset,F.L., 2006.
High density lipoprotein inhibits hepatitis C virus neutralising antibodies by stimulating cell entry via activation of the scavenger receptor BI. J Biol Chem. 2006 Jul 7;281(27):18285-95.

Koutsoudakis, G., A. Kaul, E. Steinmann, S. Kallis, V. Lohmann, T. Pietschmann, and R. Bartenschlager, 2006.
Characterization of the early steps of Hepatitis C virus infection by using luciferase reporter viruses. J Virol. 2006 Jun;80(11):5308-20.

Pietschmann,T., Kaul,A., Koutsoudakis,G., Shavinskaya,A., Kallis,S., Steinmann,E., Abid,K., Negro,F., Dreux,M., Cosset,F.L., Bartenschlager,R, 2006.
Construction and characterization of infectious intragenotypic and intergenotypic hepatitis C virus chimeras. Proc Natl Acad Sci U S A. 2006 May 9;103(19):7408-13.

Tarr, A. W., A. M. Owsianka, J. M. Timms, C. P. McClure, R. J. Brown, T. P. Hickling, T. Pietschmann, R. Bartenschlager, A. H. Patel, and J. K. Ball, 2006.
Characterization of the hepatitis C virus E2 epitope defined by the broadly neutralizing monoclonal antibody AP33. Hepatology 43:592-601.

Wakita, T.*, T. Pietschmann*, T. Kato, T. Date, M. Miyamoto, Z. Zhao, K. Murthy, A. Habermann, H.-G. Kräusslich, M. Mizokami, R. Bartenschlager*, and T.J. Liang. 2005.
Production of infectious hepatitis C virus in tissue culture from a cloned viral genome. Nature Medicine, 11:791-796. * Equal contribution.

Appel, N., T. Pietschmann, and R. Bartenschlager, 2005.
Mutational analysis of hepatitis C virus nonstructural protein 5A: potential role of differential phosphorylation in RNA replication and identification of a genetically flexible domain. J. Virol. 79:3187-3194.

Cagnon, L., P. Wagaman, R. Bartenschlager, T. Pietschmann, T. Gao, N. M. Kneteman, D. L. Tyrrell, C. Bahl, P. Niven, S. Lee, and K. A. Simmen, 2004.
Application of the trak-C HCV core assay for monitoring antiviral activity in HCV replication systems. J. Virol. Methods 118:23-31.

Kronke, J., R. Kittler, F. Buchholz, M. P. Windisch, T. Pietschmann, R. Bartenschlager, and M. Frese, 2004.
Alternative approaches for efficient inhibition of hepatitis C virus RNA replication by small interfering RNAs. J. Virol. 78:3436-3446.

Schwer, B., S. Ren, T. Pietschmann, J. Kartenbeck, K. Kaehlcke, R. Bartenschlager, T. S. Yen, and M. Ott, 2004.
Targeting of hepatitis C virus core protein to mitochondria through a novel C-terminal localization motif. J. Virol. 78:7958-7968.

Bukh, J., T. Pietschmann, V. Lohmann, N. Krieger, K. Faulk, R. E. Engle, S. Govindarajan, M. Shapiro, M. St Claire, and R. Bartenschlager, 2002.
Mutations that permit efficient replication of hepatitis C virus RNA in Huh-7 cells prevent productive replication in chimpanzees. Proc. Natl. Acad. Sci. U. S. A 99:14416-14421.

Pietschmann, T., V. Lohmann, A. Kaul, N. Krieger, G. Rinck, G. Rutter, D. Strand, and R. Bartenschlager, 2002.
Persistent and transient replication of full-length hepatitis C virus genomes in cell culture. J. Virol. 76:4008-4021.

Frese, M., T. Pietschmann, D. Moradpour, O. Haller, and R. Bartenschlager, 2001.
Interferon-alpha inhibits hepatitis C virus subgenomic RNA replication by an MxA-independent pathway. J. Gen. Virol. 82:723-733.

Pietschmann, T., V. Lohmann, G. Rutter, K. Kurpanek, and R. Bartenschlager, 2001.
Characterization of cell lines carrying self-replicating hepatitis C virus RNAs. J. Virol. 75:1252-1264.

Selected Reviews

Bartenschlager, R. and T. Pietschmann. 2005.
Efficient hepatitis C virus cell culture system: what a difference the host cell makes. Proc. Natl. Acad. Sci. 102:9739-9740.

Bartenschlager, R., M. Frese, and T. Pietschmann. 2004.
Novel insights into hepatitis C virus replication and persistence. Adv. Virus Res. 63:71-180.

Pietschmann, T. and R. Bartenschlager. 2003.
Tissue culture and animal models for hepatitis C virus. Clin. Liver Dis. 7:23-43.