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Publikationen und Patente


Prof. Dr. med. Tsvetomir Loukanov



Eichhorn JG, Ley S, Kropp F, Fink C, Brockmeier K, Loukanov T, Ley-Zaporozhan J (2019)

Aortic Coarctation a Systemic Vessel Disease-Insights from Magnetic Resonance Imaging.

Thorac Cardiovasc Surg. 2019 Dec;67(S 04):e1-e10. doi: 10.1055/s-0039-1697915. Epub 2019 Nov 1.


Jaschinski C, Cussigh C, Fonseca E, Bruckner T, Karck M, Loukanov T (2019)

A Wide Comparison of Techniques for Repair of PAPVCs: One Institution's 20-Year Experience.

Thorac Cardiovasc Surg. 2019 Aug 6. doi: 10.1055/s-0039-1693655. [Epub ahead of print]


Jaschinski C, Uzdenov M, Loukanov T (2019)

Cor triatriatum sinister with left anomalous pulmonary venous return to innominate vein.

Cardiol Young. 2019 Mar;29(3):428-430. doi: 10.1017/S1047951118002305. Epub 2019 Jan 24


Imle R, Tosev G, Behnisch W, Schenk JP, Rauch H, Mueller A, Gorenflo M, Loukanov T, Kulozik A, Nyarangi-Dix J (2019)

Intracardiac Extension of Wilms Tumor: A Case of a 2.5-Year-Old Girl Presenting with Upper Venous Congestion Caused by Tumor Growth into the Right Cardiac Ventricle.

Case Rep Oncol. 2019 Jan 4;12(1):33-38. doi: 10.1159/000496020. eCollection 2019 Jan-Apr.


Sommburg O, Helling-Bakki A, Alrajab A, Schenk JP, Springer W, Mall MA, Loukanov T, Eichhorn JG (2019)

Assessment of Suspected Vascular Rings and Slings and/or Airway Pathologies Using Magnetic Resonance Imaging Rather Than Computed Tomography.

Respiration. 2019;97(2):108-118. doi: 10.1159/000492080. Epub 2018 Oct 5.



Szczechowicz M, Mkalaluh S, Farag M, Mashhour A, Loukanov T, Kolcz J, Karck M, Weymann A (2018)

Pulmonary valve and right ventricular outflow tract surgery in adults: 23-year experience.

Kardiol Pol. 2018;76(3):602-610. doi: 10.5603/KP.a2017.0260. Epub 2018 Jan 3.



Ziesenitz VC, Loukanov T, Gläser C, Gorenflo M (2016)

Variable expression of Alagille syndrome in a family with a new JAG1 gene mutation.

Cardiol Young. 2016 Jan;26(1):164-7. doi: 10.1017/S1047951114002753. Epub 2015 Jan 23.


Ziesenitz VC, Gorenflo M, Loukanov T (2016)

Repair of an aorto-right ventricular tunnel in a newborn.

Cardiol Young. 2016 Jan;26(1):147-8. doi: 10.1017/S1047951115001572. Epub 2015 Sep 3.



Arnold RR, Loukanov T, Gorenflo M (2014)

Hypoplastic left heart syndrome - unresolved issues.

Front Pediatr. 2014 Nov 10;2:125. doi: 10.3389/fped.2014.00125. eCollection 2014


Sandrio S, Springer W, Karck M, Gorenflo M, Weymann A, Ruhparwar A, Loukanov T (2014)

Extracorporeal life support with an integrated left ventricular vent in children with a low cardiac output.

Cardiol Young. 2014 Aug;24(4):654-60. doi: 10.1017/S1047951113001017. Epub 2013 Aug 6.


Fonseca E, Georgiev SG, Gorenflo M, Loukanov TS (2014)

Patent ductus arteriosus in preterm infants: benefits of early surgical closure.

Asian Cardiovasc Thorac Ann. 2014 May;22(4):391-6. doi: 10.1177/0218492313480051. Epub 2013 Nov 5.


Sandrio S, Karck M, Gorenflo M, Loukanov T (2014)

Results of using cardiopulmonary bypass for spinal cord protection during surgical repair of complex aortic coarctation.

Cardiol Young. 2014 Feb;24(1):113-9. doi: 10.1017/S1047951113000115. Epub 2013 Feb 6.



Köhler D, Arnold R, Loukanov T, Gorenflo M (2014)

Right Ventricular Failure and Pathobiology in Patients with Congenital Heart Disease - Implications for Long-Term Follow-Up.

Front Pediatr. 2013 Nov 19;1:37


Loukanov T, Jaschinski C, Kirilov M, Klimpel H, Karck M, Gorenflo M (2013)

Cyclooxygenase-2 expression in lung in patients with congenital heart malformations and pulmonary arterial hypertension.

Thorac Cardiovasc Surg. 2013 Jun;61(4):307-11. doi: 10.1055/s-0033-1337446. Epub 2013 May 16.


Weymann A, Georgiev S, Vogelsang C, Ivad A, Karck M, Gorenflo M, Loukanov T (2013)

Temporary Tricuspid Valve Detachment For Ventricular Septal Defect Closure: Is It Worth Doing It?

Heart Surg Forum. 2013 Apr 1;16(2):E99-E102. doi: 10.1532/HSF98.20121111



Loukanov T, Takahashi H, Tonchev P, Gross J, Bettendorf M, Gorenflo M (2011)

Plasma cyclic – 3´, 5´-adenosine monophosphate (cAMP) in patients with elevated pulmonary pressure due to left-to-right shunt.

Can J Cardiol. 2011 Jul-Aug;27(4):523.e25-9. Epub 2011 Jun 8.


Loukanov T, Bucsenez D, Springer W, Sebening C, Rauch H, Roesch E, Karck M, Gorenflo M (2011)

Comparison of inhaled nitric oxide with aerosolized iloprost for treatment of pulmonary hypertension in children after

cardiopulmonary bypass surgery.

Clin Res Cardiol. 2011 Jul;100(7):595-602. Epub 2011 Feb 13


Loukanov T, Hoss K, Tonchev P, Klimpel H, Arnold R, Sebening C, Karck M, Gorenflo M (2011)

Endothelial nitric oxide synthase (eNOS) gene polymorphism (Glu298Asp) and pulmonary hypertension in children with congenital heart diseases.

Cardiol Young. 2011 Apr;21(2):161-9. Epub 2010 Dec 10.



Winterhalter M, Antoniou T, Loukanov T (2010)

Management of Adult Patients with Perioperative Pulmonary Hypertension: Technical Aspects and Therapeutic Options.

Cardiology. 2010;116(1):3-9. Epub 2010 Apr 24


Loukanov T, Geiger R, Agrawal R (2010)

Animal Models Related to Congenital Heart Disease and Clinical Research in Pulmonary Hypertension.

Cardiology. 2010;116(1):18-25. Epub 2010 Apr 24


Ley S, Loukanov T, Ley-Zaporozhan J, Springer W, Sebening C, Sommerburg O, Hagl S, Gorenflo M (2010):

Long-term outcome after external tracheal stabilization due to congenital tracheal instability.

Ann Thorac Surg. 2010 Mar;89(3):918-25.


Loukanov Ts, Kirilov M, Fürstenberger G, Müller-Decker K (2010):

Localization of cyclo-oxygenase-2 in human recurrent colorectal cancer.

Clin Invest Med. 2010 Feb 1;33(1):E22-9.



Loukanov TS, Sebening C, Springer W, Hagl S, Karck M, Gorenflo M (2009):

The evolution of the pulmonary arterial sling syndrome, with particular reference to the need for reoperations because of untreated tracheal stenosis.

Cardiol Young. 2009 Sep;19(5):446-50. doi: 10.1017/S1047951109990576. Epub 2009 Aug 7.



Loukanov T, Sebening C, Springer W, Khalil M, Ulmer HE, Hagl S, Karck M, Gorenflo M (2008):

Replacement of valved right ventricular to pulmonary artery conduits: an observational study with focus on right ventricular geometry.

Clin Res Cardiol. 2008 Mar;97(3):169-75. Epub 2007 Nov 28


Hagl S, Sebening C, Springer W, Loukanov T (2008):

Modified sliding tracheal plasty using the bridging bronchus for repair of long-segment tracheal stenosis.

Ann Thorac Surg. 2008 Mar;85(3):1118-20


Loukanov T, Arnold R, Gross J, Sebening C, Klimpel H, Eichhorn J, Hoss K, Ulmer HE, Karck M, Gorenflo M (2008):

Endothelin-1 and asymmetric dimethylarginine in children with left-to-right shunt after intracardiac repair.

Clin Res Cardiol. 2008 Jun;97(6):383-8. Epub 2008 Feb 22


Arnold R, Ley-Zaporozhan J, Ley S, Loukanov T, Sebening C, Kleber JB, Goebel B, Hagl S, Karck M, Gorenflo M (2008):

Outcome after mechanical aortic valve replacement in children and young adults.

Ann Thorac Surg. 2008 Feb;85(2):604-10



Loukanov T, Gorenflo M, Sebening C, Springer W, Eichhorn J, Ulmer H, Hagl S (2007):

Surgical treatment of long-segment tracheal anomalies in infants and children.

Thorac Cardiovasc Surg. 2007 Sep;55(6):375-379


Loukanov T, Sebening C, Gorenflo M, Hagl S (2007):

Management of congenital tracheal stenosis in infancy.

Eur J Cardiothorac Surg; Feb;31(2):331. Epub 2006 Nov 29



Loukanov T, Sebening C, Springer W, Ulmer H, Hagl S (2005):

Simultaneious management of congenital tracheal stenosis and cardiac anomalies in infants.

J Thorac Cardiovasc Surg 130: 1537-41



Loukanov T, Sebening C, Springer W, Hagl S (2004):

A case of pulmonary artery sling associated with long-segment funnel trachea

Ann Thorac Surg 78(5): 1839-42



Loukanov T, Marinov S, Lazarov S, Pilossoff V (2003):

Cardiopulmonary bypass – principles, effect on organism and possible mechanisms for decreasing of the complications. II. Inflammatory response to CPB.

Pediatrics 4: 11-17


Loukanov T, Marinov S, Lazarov S, Pilossoff V (2003):

Cardiopulmonary bypass – principles, effect on organism and possible mechanisms for decreasing of the complications. I. Mechanism and principles.

Pediatrics 4: 7-11



Loukanov T, Lazarov S, Lacheva A, Pilossoff V (2002):

Extracorporeal Memebrane Oxygenation (ECMO).

Bulg. Cardiology 4:31-36


Loukanov T, Lazarov S, Pilossoff V (2002):

Myocardial protection in pediatric heart surgery.

Bulg. Cardiology 2: 15-24



Loukanov T (2001):

Cyclooxygenase-2 (COX-2) Selective Inhibitors and Potential Mechanisms for Colorectal Cancer Chemopreventetion.

Hepatogastroenterology 67: 152-155


Loukanov T, Loukanova S, Kolchakov W, Markova E, Krastev Z (2001):

Cyclo- oxygenase 2 (COX-2) expression in preneoplastic diseases and epithelial colon cancer.

Hepatogastroenterology 67:23-27



Loukanov T (2000):

Angiogenic therapy of the malignant diseases.

In: Chernozemsky I, Shipkov T, editors. Oncology 2001. 1st ed. Ciela- Soft and Publishing; 2000. p. 199- 205.


Loukanov T (2000):

Gene therapy of the malignant diseases.

In: Chernozemsky I, Shipkov T, editors. Oncology 2001. 1st ed. Ciela- Soft and Publishing; 2000. p. 190-199



Mueller-Decker K, Albert C, Loukanov T , Winde F, Marks G, Fuerstenberger G(1999):

Cellular localisation of cyclooxygenase isoenzymes in Crohn’s colitis and colorectal cancer.

Int. Journal of Colorectal Diseases 14:212-218



Loukanov T, Botev C, Markov N, Djongov L, Dimitrov V (1998):

Fibrin tissue adhesives in surgical oncology.

Journal of B.U.ON.4: 297- 300



Patent N: 62679: Method for transfer of the distal part of the minor pectoral muscle in axillary fossa. 29.03.2000


Patent N: 62638: Autologous fibrin glue. 28.04.2000