Kliniken &… Kliniken Chirurgische Klinik… Herzchirurgie Über uns Mitarbeiter Publikationen…




Dr. med. Sivakkanan Loganathan




Korkmaz-Icöz S, Szczesny B, Marcatti M, Li S, Ruppert M, Lasitschka F, Loganathan S, Szabó C, Szabó G (2018)

Olaparib protects cardiomyocytes against oxidative stress and improves graft contractility during the early phase after heart transplantation in rats.

Br J Pharmacol. 2018 Jan;175(2):246-261. doi: 10.1111/bph.13983. Epub 2017 Oct 2.





Li S, Korkmaz-Icöz S, Radovits T, Ruppert M, Spindler R, Loganathan S, Hegedűs P, Brlecic P, Theisinger B, Theisinger S, Höger S, Brune M, Lasitscha F, Karck M, Yard B, Szabó G (2017)

Donor preconditioning after the onset of brain death with dopamine derivate n-octanoyl dopamine improves early posttransplant graft function in the rat.

Am J Transplant. 2017 Jul;17(7):1802-1812. doi: 10.1111/ajt.14207. Epub 2017 Feb 28.





Loganathan S, Korkmaz-Icöz S, Radovits T, Li S, Mikles B, Barnucz E, Hirschberg K, Karck M, Szabó G (2015)

Effects of soluble guanylate cyclase activation on heart transplantation in a rat model.

J Heart Lung Transplant. 2015 Oct;34(10):1346-53. doi: 10.1016/j.healun.2015.05.006. Epub 2015 Jun 11


Korkmaz S, Atmanli A, Li S, Radovits T, Hegedus P, Barnucz E, Hirschberg K, Loganathan S, Yoshikawa Y, Yasui H, Karck M, Szabó G (2015)

Superiority of zinc complex of acetylsalicylic acid to acetylsalicylic acid in preventing postischemic myocardial dysfunction.

Exp Biol Med (Maywood). 2015 Sep;240(9):1247-55. doi: 10.1177/1535370215570184. Epub 2015 Feb 9


Li S, Loganathan S, Korkmaz S, Radovits T, Hegedűs P, Zhou Y, Karck M, Szabó G (2015)

Transplantation of donor hearts after circulatory or brain death in a rat model.

J Surg Res. 2015 May 1;195(1):315-24. doi: 10.1016/j.jss.2014.12.038. Epub 2014 Dec 24.


Li S, Korkmaz S, Loganathan S, Radovits T, Hegedüs P, Karck M, Szabó G (2014)

Short-term and long-term effects of brain death on posttransplant graft function in a rodent model.

Interact Cardiovasc Thorac Surg. 2015 Mar;20(3):379-86. doi: 10.1093/icvts/ivu403. Epub 2014 Dec 11.


Radovits T, Korkmaz S, Mátyás C, Oláh A, Németh BT, Páli S, Hirschberg K, Zubarevich A, Gwanmesia PN, Li S, Loganathan S, Barnucz E, Merkely B, Szabó G (2015)

An altered pattern of myocardial histopathological and molecular changes underlies the different characteristics of type-1 and type-2 diabetic cardiac dysfunction.

J Diabetes Res. 2015;2015:728741. doi: 10.1155/2015/728741. Epub 2015 Jan 5.





Korkmaz S, Bährle-Szabó S, Loganathan S, Li S, Karck M, Szabó G (2013)

Marginal donors: can older donor hearts tolerate prolonged cold ischemic storage?

Aging Clin Exp Res. 2013 Oct;25(5):597-600. doi: 10.1007/s40520-013-0131-9. Epub 2013 Aug 15.


Korkmaz S, Barnucz E, Loganathan S, Li S, Radovits T, Hegedüs P, Zubarevich A, Hirschberg K, Weymann A, Puskás LG, Ózsvári B, Faragó N, Kanisai I, Fábián G, Gyuris M, Merkely B, Karck M, Szabó S, Szabó G (2013)

Q50, an iron-chelating and zinc-complexing agent, improves cardiac function in rat models of ischemia/reperfusion-induced myocardial injury.

Circ J. 2013;77(7):1817-26. Epub 2013 Apr 11.


Korkmaz S, Loganathan S, Mikles B, Radovits T, Barnucz E, Hirschberg K, Li S, Hegedüs P, Páli S, Weymann A, Karck M, Szabó G (2013)

Nitric Oxide- and Heme-Independent Activation of Soluble Guanylate Cyclase Attenuates Peroxynitrite-Induced Endothelial Dysfunction in Rat Aorta.

J Cardiovasc Pharmacol Ther. 2013 Jan;18(1):70-7. doi: 10.1177/1074248412455696. Epub 2012 Aug 22


Weymann A, Schmack B, Okada T, Soos P, Istok R, Radovits T, Straub B, Barnucz E, Loganathan S, Paetzold I, Chaimow N, Schies C, Korkmaz S, Tochtermann U, Karck M, Szabo G (2013)

Reendothelialization of Human Heart Valve Neoscaffolds Using Umbilical Cord Derived Endothelial Cells.

Circ J. 2013;77(1):207-16. Epub 2012 Sep 21.






Li S, Korkmaz S, Loganathan S, Weymann A, Radovits T, Barnucz E, Hirschberg K, Hegedüs P, Zhou Y, Tao L, Pali S, Veres G, Karck M, Szabo G (2012)

Acute Ethanol Exposure Increases the Susceptibility of the Donor Hearts to Ischemia/Reperfusion Injury after Transplantation in Rats.

PLoS One. 2012;7(11):e49237. doi: 10.1371/journal.pone.0049237. Epub 2012 Nov 14.


Szabó G, Loganathan S, Merkely B, Groves JT, Karck M, Szabó C, Radovits T (2012)

Catalytic peroxynitrite decomposition improves reperfusion injury after heart transplantation.

J Thorac Cardiovasc Surg. 2012 Jun;143(6):1443-9. Epub 2012 Mar 7.


Hirschberg K, Tarcea V, Páli S, Barnucz E, Gwanmesia PN, Korkmaz S, Radovits T, Loganathan S, Merkely B, Karck M, Szabó G (2012)

Cinaciguat prevents neointima formation after arterial injury by decreasing vascular smooth muscle cell migration and proliferation.

Int J Cardiol. 2012 Feb 20. [Epub ahead of print]


Loganathan S, Radovits T, Korkmaz S, Hirschberg K, Barnucz E, Weymann A, Bömicke T, Arif R, Karck M, Szabó G (2012)

Enhancement of Myocardial and Vascular Function after Phosphodiesterase-5 Inhibition in a Rat Model.

Thorac Cardiovasc Surg. 2012 Jun;60(4):247-54. Epub 2012 Jan 17.






Weymann A, Loganathan S, Takahashi H, Schies C, Claus B, Hirschberg K, Soós P, Korkmaz S, Schmack B, Karck M, Szabó G (2011)

Development and Evaluation of a Perfusion Decellularization Porcine Heart Model: Generation of Three-Dimensional Myocardial Neoscaffolds.

Circ J. 2011 Mar 25;75(4):852-60. Epub 2011 Feb 2.







Loganathan S, Radovits T, Hirschberg K, Korkmaz S, Koch A, Karck M, Szabó G (2010)

Effects of Custodiol-N, a Novel Organ Preservation Solution, on Ischemia/Reperfusion Injury.

J Thorac Cardiovasc Surg. 2010 Apr;139(4):1048-56. Epub 2009 Nov 27


Loganathan S, Nieh CC, Emmert MY, Woitek F, Martinez EC, Muecke S, Lee CN, Kofidis T (2010):

Off-Pump Versus On-Pump Coronary Artery Bypass Procedures: Post-Operative Renal Complications in an Asian Population.

Ann Acad Med Singapore. 2010 Feb;39(2):112-6


Hirschberg K, Radovits T, Korkmaz S, Loganathan S, Zöllner S, Seidel B, Páli Sz, Barnucz E, Merkely B, Karck M, Szabó G (2010)

Combined superoxide dismutase mimetic and peroxynitrite scavenger protects against neointima formation after endarterectomy in association with decreased proliferation and nitro-oxidative stress.

Eur J Vasc Endovasc Surg. 2010 Aug;40(2):168-75


Koch A, Loganathan S, Radovits T, Sack FU, Karck M, Szabó GB (2010):

Deferoxamine, the newly developed iron chelator LK-614 and N-alpha-acetyl-histidine in myocardial protection.

Interact Cardiovasc Thorac Surg. 2010 Feb;10(2):181-4. Epub 2009 Nov 13.







Koch A, Radovits T, Loganathan S, Sack FU, Karck M, Szabó GB (2009):

Myocardial protection with the use of L-arginine and N-alpha-acetyl-histidine.

Transplant Proc. 2009 Jul-Aug;41(6):2592-4


Korkmaz S, Radovits T, Barnucz E, Hirschberg K, Neugebauer P, Loganathan S, Veres G, Pali S, Seidel B, Zöllner S, Karck M, Szabo G (2009):

Pharmacological activation of soluble guanylate cyclase protects the heart against ischemic injury.

Circulation. 2009 Aug 25;120(8):677-86. Epub 2009 Aug 10


Korkmaz S, Radovits T, Barnucz E, Neugebauer P, Arif R, Hirschberg K, Loganathan S, Seidel B, Karck M, Szabó G (2009):

Dose-dependent effects of a selective phosphodiesterase-5-inhibitor on endothelial dysfunction induced by peroxynitrite in rat aorta.

Eur J Pharmacol. 2009 Aug 1;615(1-3):155-62. Epub 2009 May 29


Radovits T, Korkmaz S, Loganathan S, Barnucz E, Bömicke T, Arif R, Karck M, Szabó G (2009):

Comparative investigation of the left ventricular pressure-volume relationship in rat models of type 1 and type 2 diabetes mellitus.

Am J Physiol Heart Circ Physiol. 2009 Jul;297(1):H125-33. Epub 2009 May 8


Radovits T, Bömicke T, Kökény G, Arif R, Loganathan S, Kécsán K, Korkmaz S, Barnucz E, Sandner P, Karck M, Szabó G (2009)

The phosphodiesterase-5 inhibitor vardenafil improves cardiovascular dysfunction in experimental diabetes mellitus.

Br J Pharmacol 2009; 156 (6); 909-19


Szabó G, Radovits T, Veres G, Krieger N, Loganathan S, Sandner P, Karck M (2009):

Vardenafil protects against myocardial and endothelial injuries after cardiopulmonary bypass.

Eur J Cardiothorac Surg. 2009 Oct;36(4):657-64. Epub 2009 Jun 11


Hirschberg K, Radovits T, Loganathan S, Entz L, Beller CJ, Gross ML, Sandner P, Karck M, Szabó G (2009):

Selective phosphodiesterase-5 inhibition reduces neointimal hyperplasia in rat carotid arteries after surgical endarterectomy.

J Thorac Cardiovasc Surg. 2009 Jun;137(6):1508-14. Epub 2009 Feb 10






Radovits T, Gerö D, Lin LN, Loganathan S, Hoppe-Tichy T, Szabó C, Karck M, Sakurai H, Szabó G (2008):

Improvement of Aging-Associated Cardiovascular Dysfunction by the Orally Administered Copper(II)-Aspirinate Complex.

Rejuvenation Res. 2008 Oct;11(5):945-56


Loganathan S, Radovits T, Hirschberg K, Korkmaz S, Barnucz E, Karck M, Szabó G (2008):

Effects of Selective Phosphodiesterase-5-Inhibition on Myocardial Contractility and Reperfusion Injury After Heart Transplantation.

Transplantation. 2008 Nov 27;86(10):1414-8