Kliniken & Institute … Institute Institut für… Forschung Arbeitsgruppen Statistical Genetics … Research Training

Heidelberg International Summer School for Doctoral Students


20–24 November 2023
Heidelberg Center Latin America, Santiago de Chile

This summer school aims to bring together scientists working at the interface of statistical genetics and molecular medicine to discuss the opportunities and challenges arising from genetic ancestry and inbreeding for P4-Medicine.

The summer school will be held at the Heidelberg Center Latin America from 20–24 November, with a preparatory online meeting on 16 October 2023.



Rachel Kelley
Harvard Medical School, USA
Research Focus: Metabolomic Epidemiology of Complex Disease
- Metabolomics: the missing link between genotype and phenotype

Yolanda Espinosa Parrilla
University of Magallanes, Chile
Research Focus: Non-coding RNAs in evolution and disease
- microRNAs as gastric cancer biomarkers: the MAGIC study and outline of Magallanes cohort

David Hughes
University College Dublin, Ireland
Research Focus: Gut Barrier Dysfunction and Microbiome Dysbiosis
- Association of gut barrier integrity and microbial metabolites with gastrointestinal cancer risk

Vinay Kapoor
Mahatma Gandhi Medical College & Hospital, India
Research Focus: Gallbladder Cancer
- Gallbladder cancer: what is it and what are the issues?
- Gallbladder cancer - what needs to be done?


Francisco Ceballos
Centro de Investigación Biomédica en Red, Spain
Research Focus: Demographic history, genetic architecture of complex traits, autozygosity
- Latin American homozygosity and gallbladder cancer

James Wilson
The University of Edinburgh, UK
Research Focus: Population genetics
- Runs of homozygosity: windows into population history and trait architecture
- Ancestry differences in rare actionable and Mendelian variants: case study in the Northern Isles of Scotland

Arce Domingo Relloso
Columbia University Mailman School of Public Health, USA
Research Focus: Biostatistics, epigenetics and omics data, environmental epidemiology
- Arsenic, epigenetics and cardiovascular disease: an inter-disciplinary approach for community-based research
- Multiple mediation in omics data: application to smoking, DNA methylation and lung cancer

Robert Kaplan
Albert Einstein College of Medicine, USA
Research Focus: Epidemiology and Population Health
- Application of genetics to epidemiological study of US Latinos
- Gut microbiome, metabolite and genetics affecting diet-related disease

Augustin Scalbert
Research Focus: Biomarkers, cancer epidemiology, metabolomics
- Metabolomics and biomarker discovery in cancer epidemiology

Felipe Martínez
Pontificia Universidad Católica de Chile, Chile
Research Focus: Human Evolution and Diversity
- Human population genomics: how can we communicate better?

  • Introduction to Mendelian Randomization (organized within the EU-funded research project EULAT Eradicate GBC)
  • Biostatistical Analysis of Genotype Data (organized within the EU-funded research project EULAT Eradicate GBC)
  • Statistical Genetics and Genetic Epidemiology, Bioinformatics, and Study Designs in Biometry and Epidemiology (MSc in Medical Informatics, University of Heidelberg)
  • Biostatistics, Genetic Epidemiology and Advanced Statistical Methods (MSc in Medical Informatics organized by University of Heidelberg and University of Chile)
  • Introduction to Bioinformatics, Introduction to Bayesian Statistics and Genetic Epidemiology (MSc in Medical Biometry/Biostatistics, University of Heidelberg)
  • Epidemiology, Major in Cancer Biology organized by the Faculty of Biosciences, University of Heidelberg in collaboration with the German Cancer Research Center
  • Descriptive Exploratory and Confirmatory Statistical Analysis (Training in Clinical Research organized by the Bolivian National Health Fund)
  • Genetic Epidemiology and Introduction to Bayesian Statistics (MSc in Epidemiology, Medical Biometry/Biostatistics, University of Mainz)

The Statistical Genetics Journal Club aims at discussing relevant articles, software and databases in the field of statistical for molecular medicine.

The Journal Club meets on a regular basis every two weeks. If you wish to be notified of upcoming Journal Clubs, please email us at the following address: lorenzo@imbi.uni-heidelberg.de. If you are interested in details about former Journal Clubs, please contact directly the speaker.

Recent Topics:

  • Identification and validation of circulating µRNAs associated with gallbladder cancer risk in Europeans
    A. Blandino
  • Risk of Cancer after Cholecystectomy in Sweden
    E. Kharazmi
  • Genetic-genomic characterization of Chilean patients with gallbladder cancer
    V. Gárate
  • Genetically determined gene expression levels and survival of colorectal cancer patients
    H. Deutelmoser
  • UK Biobank data and data retrieval
    J. Lorenzo Bermejo, F. Boekstegers
  • Power calculations in Mendelian Randomization Studies
    J. Lorenzo Bermejo, C. Barahona Ponce, L. Zollner
  • Aspirin, gallbladder cancer and colorectal adenomas – Mendelian Randomization Studies D. Scherer
  • Introduction to the article:
    McGregor et al. "An evaluation of methods correcting for cell-type heterogeneity in DNA methylation studies"
    J. Brägelmann
  • Introduction to linkage analysis
    C. Fischer
  • Introduction to the article:
    Ghani et al. "Evidence of Recessive Alzheimer Disease Loci in a Caribbean Hispanic Data Set Genome-wide Survey of Runs of Homozygosity" 
    C. Fischer