Institute for Medical… Research Medical Data… 3LGM2IHE


Funding Organisation: DFG

Duration: 01/2020 - 03/2023

Funding volume: 300,000 EUR (IMI), total approx. 790,000 EUR


Modeling support for interoperable information systems

Cooperation partner

TMF Berlin and University Hospitals Leipzig, Kiel, Greifswald


Information systems of clinical research projects are complex. The complexity results from the multitude of regulatory, professional and technical constraints and the tasks to be supported, such as the administration of subjects, study data or biomaterials. In addition to such administrative tasks, the exchange of research data across projects and the integration of research and care are becoming increasingly important. A subset of the requirements is relevant for different research projects of similar type (clinical trial, registry, cohort study, etc.).

However, solution architectures for research projects are often repeatedly designed and implemented independently. Reusability and interoperability of software modules beyond the specific research project are often neglected. Integrating the Healthcare Enterprise(IHE) is an international initiative that bundles requirements from practice into use cases and develops technical guidelines in the form of IHE profiles. Based on the IHE profiles, information system architectures are possible that consist of reusable and interoperable software modules. However, for the information manager of a research project without IHE experience, getting started and keeping track of the multitude of IHE profiles is difficult.

The research project - Planning Support for Interoperable Information Systems in Clinical Research (3LGM2IHE) - therefore aims at modeling the concepts of the IHE specifications completely in Enterprise Architecture Planning tool 3LGM2 construction kit. Furthermore, design patterns shall be provided that map typical services of a research information system to IHE profiles. The design patterns shall support the information manager of a research project to find suitable IHE profiles and to construct a concrete research information system. The design patterns will be evaluated with respect to their usefulness in planning a research information system and will be provided to the users together with adapted 3LGM2 construction kits as well as corresponding instructions for action. Dissemination of the research results will be done via the IHE Wiki, integration into the IHE-D Cookbook and via the TMF Service Portal.