Kliniken & Institute … Kliniken Neurologische Klinik … Neurologie und… Forschung Publications


Publications 2020 (PDF)

Publications 2019 (PDF)

Publications 2018 (PDF)

Publications 2017 (PDF)

Publications 2016 (PDF)

Publications 2015 (PDF)

We have published a series of major papers improving our understanding of neurological diseases. In 2015/2016, our department published more than 300 papers and top publications reaching the 3rd place (together with the department of Pharmacology) in the Heidelberg University Hospital publication ranking. Our most significant discoveries in 2019 include:

Berberich A, Kessler T, Thomé CM, Pusch S, Hielscher T, Sahm F, Oezen I, Schmitt LM, Ciprut S, Hucke N, Rübmann P, Fischer M, Lemke D, Breckwoldt MO, von Deimling A, Bendszus M, Platten M, Wick W. Targeting resistance against the MDM2 inhibitor RG7388 in glioblastoma cells by the MEK inhibitor trametinib. Clin Cancer Res. 2019 Jan 1;25(1):253-265

Berberich, A., C. Schneider, T. Reiff, C. Gumbinger and P. A. Ringleb (2019). Dual Antiplatelet Therapy Improves Functional Outcome in Patients With Progressive Lacunar Strokes. Stroke. 2019 Apr;50(4):1007-1009

Bruce C V Campbell*, Henry Ma*, Peter A Ringleb*, Mark W Parsons, Leonid Churilov, Martin Bendszus, Christopher R Levi, Chung Hsu, Timothy J Kleinig, Marc Fatar, Didier Leys, Carlos Molina, Tissa Wijeratne, …, Danilo Toni, Vincent Thijs, Werner Hacke†, Stephen M Davis†, Geoffrey A Donnan†, on behalf of the EXTEND, ECASS-4, and EPITHET Investigators‡. Extending thrombolysis to 4·5–9 h and wake-up stroke using perfusion imaging: a systematic review and meta-analysis of individual patient data. Lancet. 2019 Jul 13;394(10193):139-147

Campbell, B. C. V., H. Ma, P. A. Ringleb, M. W. Parsons, L. Churilov, M. Bendszus, C. R. Levi, C. Hsu, T. J. Kleinig, M. Fatar, D. Leys, C. Molina, T. Wijeratne, S. Curtze, H. M. Dewey, P. A. Barber, K. S. Butcher, D. A. De Silva, C. F. Bladin, N. Yassi, J. A. R. Pfaff, G. Sharma, A. Bivard, P. M. Desmond, S. Schwab, P. D. Schellinger, B. Yan, P. J. Mitchell, J. Serena, D. Toni, V. Thijs, W. Hacke, S. M. Davis and G. A. Donnan (2019). Extending thrombolysis to 4.5-9 h and wake-up stroke using perfusion imaging: a systematic review and meta-analysis of individual patient data. Lancet. 2019 Jul 13;394(10193):139-147

Hilf N, Kuttruff-Coqui S, Frenzel K, Bukur V, Stevanović S, Gouttefangeas C, Platten M, …, Rusch E, Bunse L, Song C, Heesch S, Wagner C, Kemmer-Brück A, Ludwig J, Castle JC, Schoor O, Tadmor AD, Green E, Fritsche J, Dietrich PY, Wick W. Actively personalized vaccination trial for newly diagnosed glioblastoma. Nature. 2019 Jan;565(7738):240-245

Jordan, B., S. Zierz, T. Weber and K. Jordan (2019). Successful use of an immune checkpoint inhibitor in a patient with myasthenia gravis in remission. Muscle Nerve. 2019 Jul;60(1):E7-E8

Kickingereder, P., F. Isensee, I. Tursunova, J. Petersen, U. Neuberger, D. Bonekamp, G. Brugnara, M. Schell, T. Kessler, M. Foltyn, I. Harting, F. Sahm, M. Prager, M. Nowosielski, A. Wick, M. Nolden, A. Radbruch, J. Debus, H. P. Schlemmer, S. Heiland, M. Platten, A. von Deimling, M. J. van den Bent, T. Gorlia, W. Wick, M. Bendszus and K. H. Maier-Hein (2019). Automated quantitative tumour response assessment of MRI in neuro-oncology with artificial neural networks: a multicentre, retrospective study. Lancet Oncol. 2019 May;20(5):728-740

Nowosielski, M., T. Gorlia, J. E. C. Bromberg, F. Sahm, I. Harting, P. Kickingereder, A. A. Brandes, M. J. B. Taphoorn, W. Taal, J. Domont, A. Idbaih, M. Campone, P. M. Clement, M. Weller, M. Fabbro, E. Le Rhun, M. Platten, V. Golfinopoulos, M. J. van den Bent, M. Bendszus and W. Wick. Imaging necrosis during treatment is associated with worse survival in EORTC 26101 study. Neurology. 2019 Jun 11;92(24):e2754-e2763

Schönenberger S, Weber D, Ungerer MN, Pfaff J, Schieber S, Uhlmann L, Heidenreich P, Bendszus M, Kieser M, Wick W, Möhlenbruch MA, Ringleb PA, Bösel J. The KEEP SIMPLEST Study: Improving In-House Delays and Periinterventional Management in Stroke Thrombectomy-A Matched Pair Analysis. Neurocrit Care. 2019 Aug;31(1):46-55

Stojic A, Bojcevski J, Williams SK, Bas-Orth C, Nessler S, Linington C, Diem R, Fairless R. Preclinical stress originates in the rat optic nerve head during development of autoimmune optic neuritis. Glia. 2019 Mar;67(3):512-524

Venkataramani V, Tanev DI, Strahle C, Studier-Fischer A, Fankhauser L, Kessler T, Körber C, Kardorff M, Ratliff M, Xie R, Horstmann H, Messer M, Paik SP, Knabbe J, Sahm F, Kurz FT, Acikgöz AA, Herrmannsdörfer F, Agarwal A, Bergles DE, Chalmers A, Miletic H, Turcan S, Mawrin C, Hänggi D, Liu HK, Wick W, Winkler F, Kuner T. Glutamatergic synaptic input to glioma cells drives brain tumour progression. Nature. 2019 Sep;573(7775):532-538

Wick W, Dettmer S, Berberich A, Kessler T, Karapanagiotou-Schenkel I, Wick A, Winkler F, Pfaff E, Brors B, Debus J, Unterberg A, Bendszus M, Herold-Mende C, Eisenmenger A, von Deimling A, Jones DTW, Pfister SM, Sahm F, Platten M. N2M2 (NOA-20) phase I/II trial of molecularly matched targeted therapies plus radiotherapy in patients with newly diagnosed non-MGMT hypermethylated glioblastoma. Neuro Oncol. 2019 Jan 1;21(1):95-105