Priv. - Doz. Dr. med. Philippe Grieshaber

Zertifikat „Chirurgie angeborener Herzfehler“, Deutsche Gesellschaft für Thorax-, Herz- und Gefäßchirurgie

Oberarzt für Kinderherzchirurgie

Weiterbildung Kinderherzchirurgie, Sektion Kinderherzchirurgie, Klinik für Herzchirurgie, Universtitätsklinikum Heidelberg

Zusatzbezeichnung „Intensivmedizin“ (Landesärztekammer Hessen)

Oberarzt, Klinik für Herz-, Kinderherz- und Gefäßchirurgie, Universitätsklinikum Gießen

Facharztanerkennung „Herzchirurgie“ (Landesärztekammer Hessen)

Assistenzarzt, Klinik für Herz-, Kinderherz- und Gefäßchirurgie, Universitätsklinikum Gießen

Habilitation: „Strategien zur Präkonditionierung und Protektion des Myokards bei chirurgischer Myokardrevaskularisation“ mit Erteilung der Venia Legendi für das Fach Herzchirurgie und Ernennung zum Privatdozenten durch den Fachbereich 11 der Justus-Liebig-Universität Gießen

Lehrbeauftragter der Klinik für Herz-, Kinderherz- und Gefäßchirurgie, Universitätsklinikum Gießen

Ärztlicher Leiter des klinischen Studienzentrums an der Klinik für Herz-, Kinderherz- und Gefäßchirurgie, Universitätsklinikum Gießen

Promotion in der Universitäts-Augenklinik Freiburg, AG Neuroprotektion (Doktorvater: Prof. Dr. W.A. Lagrèze) mit dem Thema: „Protektion retinaler Ganglienzellen in vivo mit dem Histondeacetylaseinhibitor Valproinsäure“

Approbation

Studium Humanmedizin, Albert-Ludwigs-Universität Freiburg i.Br.

Studium Rechtswissenschaften, Albert-Ludwigs-Universität Freiburg i.Br.

Mitglied bei der European Association for Cardiothoracic Surgery (EACTS)

Ordentliches Mitglied der American Society for Artificial Internal Organs (ASAIO)

Ordentliches Mitglied der Deutschen Gesellschaft für Herz-, Thorax- und Gefäßchirurgie (DGTHG)

„Dr. Rusche-Forschungsprojekt“ der Deutschen Stiftung für Herzforschung und der Deutschen Gesellschaft für Herz-, Thorax- und Gefäßchirurgie

Young Investigator Award (Kategorie Koronare Herzerkrankung) der Deutschen Gesellschaft für Kardiologie

Grieshaber P, Farag M, Fonseca-Escalante E, Loukanov T (2024)

Perfusion During Aortic Arch Surgery-Keep it Physiologic!

World J Pediatr Congenit Heart Surg. 2024 Jan 9:21501351231221427. doi: 10.1177/21501351231221427. Online ahead of print. PMID: 38196329 No abstract available. 

Möbius A, Grieshaber P, Turra J, Riesterer D, Zaradzki M, Soso P, Hatiboglu G, Hohenfellner M, Warnecke G, Tochtermann U (2023)

Cavoatrial hypernephroma resection on cardiopulmonary bypass: Mild/normo-versus moderate hypothermia.

Perfusion. 2023 Nov;38(8):1644-1651. doi: 10.1177/02676591221128143. Epub 2022 Sep 20. PMID: 36125270 Free PMC article. 

Uhl S, Grieshaber P, Arnold R, Loukanov T, Gorenflo M (2023)

Impact of hybrid procedure on pulmonary arterial dimensions and right ventricular load after biventricular repair.

J Cardiothorac Surg. 2023 Feb 7;18(1):65. doi: 10.1186/s13019-023-02162-z. PMID: 36750898 Free PMC article.

Heer T, von Scheidt M, Boening A, Heyken C, Gusmini F, de Waha A, Kuna C, Fach A, Grothusen C, Oberhoffer M, Knosalla C, Walther T, Danner BC, Misfeld M, Wimmer-Greinecker G, Siepe M, Grubitzsch H, Joost A, Schaefer A, Conradi L, Cremer J, Hamm C, Lange R, Radke PW, Schulz R, Laufer G, Grieshaber P, Attmann T, Schmoeckel M, Meyer A, Ziegelhöffer T, Hambrecht R, Sandner SE, Kastrati A, Schunkert H, Zeymer U (2022)

Prognostic impact of secondary prevention after coronary artery bypass grafting-insights from the TiCAB trial.

Eur J Cardiothorac Surg. 2022 Aug 3;62(3):ezac048.doi: 10.1093/ejcts/ezac048. 

Grieshaber P, Merbecks M, Jaschinski C, Fonseca E, Arnold R, Karck M, Gorenflo M, Loukanov T (2022)

Surgical Treatment Following Stent Angioplasty for High-Risk Neonates With Critical Coarctation of the Aorta.

World J Pediatr Congenit Heart Surg. 2022 Jul;13(4):426-435. doi: 10.1177/21501351221099933. PMID: 35757941 Free PMC article.

Kuehn C, Ruemke S, Rellecke P, Lichtenberg A, Joskowiak D, Hagl C, Hassan M, Leyh RG, Erler S, Garbade J, Eifert S, Grieshaber P, Boening A, Doenst T, Velichkov I, Madej T, Knaut M, Hain A, Burger H (2022)

Wearable cardioverter defibrillator multicentre experience in a large cardiac surgery cohort at transient risk of sudden cardiac death.

Eur J Cardiothorac Surg. 2022 May 2;61(5):1031-1040. doi: 10.1093/ejcts/ezac086. 

von Groote TC, Ostermann M, Forni LG, Meersch-Dini M, Zarbock A; PrevAKI Investigators (2022)

The AKI care bundle: all bundle components are created equal-are they?

Intensive Care Med. 2022 Feb;48(2):242-245. doi: 10.1007/s00134-021-06601-0. Epub 2021 Dec 18. PMID: 34921624; PMCID: PMC8799533.

Veitinger AB, Komguem A, Assling-Simon L, Heep M, Schipke J, Mühlfeld C, Niemann B, Grieshaber P, Boengler K, Böning A (2021)

Cardioprotection with esmolol- based cardioplegia for non-infarcted and infarcted rat hearts.

Eur J Cardiothorac Surg. 2021 Oct 22;60(4):908-917. doi: 10.1093/ejcts/ezab117. PMID: 33709143.

Oswald I, Boening A, Pons-Kuehnemann J, Grieshaber P (2021)

Wound Infection after CABG Using Internal Mammary Artery Grafts: A Meta-Analysis.

Thorac Cardiovasc Surg. 2021 Oct;69(7):639-648. doi: 10.1055/s-0040-1713662. Epub 2020 Aug 13. PMID: 32791543. 

Zarbock A, Küllmar M, Ostermann M, Lucchese G, Baig K, Cennamo A, Rajani R, McCorkell S, Arndt C, Wulf H, Irqsusi M, Monaco F, Di Prima AL, García Alvarez M, Italiano S, Miralles Bagan J, Kunst G, Nair S, L'Acqua C, Hoste E, Vandenberghe W, Honore PM, Kellum JA, Forni LG, Grieshaber P,  Massoth C, Weiss R, Gerss J, Wempe C, Meersch M (2021)

Prevention of Cardiac Surgery-Associated Acute Kidney Injury by Implementing the KDIGO Guidelines in High-Risk Patients Identified by Biomarkers: The PrevAKI-Multicenter Randomized Controlled Trial.

Anesth Analg. 2021 Aug 1;133(2):292-302. doi: 10.1213/ANE.0000000000005458. PMID: 33684086.

Niemann B, Dominik E, Rohrbach S, Grieshaber P, Roth P, Böning A (2019)

The Same is Not the Same: Device Effect during Bipolar Radiofrequency Ablation of Atrial Fibrillation.

Thorac Cardiovasc Surg. 2021 Mar;69(2):124-132.doi: 10.1055/s-0039-1698402. Epub 2019 Oct 11.

Grieshaber P, Arneth B, Steinsberger F, Niemann B, Oswald I, Renz H, Böning A (2019)

Influence of Left Atrial Appendage Amputation on Natriuretic Peptides-A Randomized Controlled Trial.

Thorac Cardiovasc Surg. 2021 Mar;69(2):117-123.doi: 10.1055/s-0039-1683955. Epub 2019 Mar 31.

Gehron J, Bongert M, Böning A, Grieshaber P; EMPACS (Exploration of the mixing phenomena during interaction of internal and external circulations) study group (2021)

Should we be concerned about combining extracorporeal support and mechanical left ventricular unloading?

Eur J Cardiothorac Surg. 2021 Jan 4;59(1):286-287. doi: 10.1093/ejcts/ezaa225. PMID: 32772091.

Roth P, Stella J, Niemann B, Grieshaber P, Roehrig R, Böning A. (2020)

Fibrin-Coated Collagen Fleece Seems to Prevent Sternal Instability after Cardiac Surgery: A Matched Pair Data Analysis.

Thorac Cardiovasc Surg. 2020 Dec;68(8):737-742.doi: 10.1055/s-0038-1667326. Epub 2018 Aug 28.

Kube T, Meyer J, Grieshaber P, Moosdorf R, Böning A, Rief W (2019)

Patients' pre- and postoperative expectations as predictors of clinical outcomes six months after cardiac surgery.

Psychol Health Med. 2020 Aug;25(7):781-792.doi: 10.1080/13548506.2019.1659986. Epub 2019 Aug 27.

Grieshaber P, Möller S, Arneth B, Roth P, Niemann B, Renz H, Böning A (2019)

Predicting Cardiac Surgery-Associated Acute Kidney Injury Using a Combination of Clinical Risk Scores and Urinary Biomarkers.

Thorac Cardiovasc Surg. 2020 Aug;68(5):389-400.doi: 10.1055/s-0039-1678565. Epub 2019 Feb 11.

Gehron J, Schuster M, Rindler F, Bongert M, Böning A, Krombach G, Fiebich M, Grieshaber P; EMPACS (Exploration of the mixing phenomena during interaction of internal and external circulations) study group (2020)

Watershed phenomena during extracorporeal life support and their clinical impact: a systematic in vitro investigation.

ESC Heart Fail. 2020 Aug;7(4):1850-1861. doi: 10.1002/ehf2.12751. Epub 2020 Jun 12. PMID: 32530129; PMCID: PMC7373893.

Weidenmann V, Robinson NB, Rong LQ, Hameed I, Naik A, Morsi M, Grieshaber P, Böning A, Girardi LN, Gaudino M (2020)

Diagnostic dilemma of perioperative myocardial infarction after coronary artery bypass grafting: A review.

Int J Surg. 2020 Jul;79:76-83. doi: 10.1016/j.ijsu.2020.05.036. Epub 2020 May 19. PMID: 32442689; PMCID: PMC7853700.
 

Grieshaber P, Oswald I, Albert M, Reents W, Zacher M, Roth P, Niemann B, Dörr O, Krüger T, Nef H, Sodah A, Hamm C, Schlensak C, Diegeler A, Sedding D, Franke U, Boening A (2020)

Risk of perioperative coronary stent stenosis or occlusion in patients with previous percutaneous coronary intervention undergoing coronary artery bypass grafting surgery.

Eur J Cardiothorac Surg. 2020 Jun 1;57(6):1122-1129.doi: 10.1093/ejcts/ezaa003.

Küllmar M, Massoth C, Ostermann M, Campos S, Grau Novellas N, Thomson G, Haffner M, Arndt C, Wulf H, Irqsusi M, Monaco F, Di Prima A, Garcia Alvarez M, Italiano S, Cegarra SanMartin V, Kunst G, Nair S, L'Acqua C, Hoste EAJ, Vandenberghe W, Honore P, Kellum J, Forni L, Grieshaber P, Weiss R, Gerss J, Wempe C, Meersch M, Zarbock A (2020)

Biomarker-guided implementation of the KDIGO guidelines to reduce the occurrence of acute kidney injury in patients after cardiac surgery (PrevAKI-multicentre): protocol for a multicentre, observational study followed by randomised controlled feasibility trial.

BMJ Open. 2020 Apr 6;10(4):e034201. doi: 10.1136/bmjopen-2019-034201.

Küllmar M, Weiß R, Ostermann M, Campos S, Grau Novellas N, Thomson G, Haffner M, Arndt C, Wulf H, Irqsusi M, Monaco F, Di Prima AL, García-Alvarez M, Italiano S, Felipe Correoso M, Kunst G, Nair S, L'Acqua C, Hoste E, Vandenberghe W, Honore PM, Kellum JA, Forni L, Grieshaber P, Wempe C, Meersch M, Zarbock A (2020)

A Multinational Observational Study Exploring Adherence With the Kidney Disease: Improving Global Outcomes Recommendations for Prevention of Acute Kidney Injury After Cardiac Surgery.

Anesth Analg. 2020 Apr;130(4):910-916. doi: 10.1213/ANE.0000000000004642.

Boening A, Hinke M, Heep M, Boengler K, Niemann B, Grieshaber P (2020)

Cardiac surgery in acute myocardial infarction: crystalloid versus blood cardioplegia - an experimental study.

J Cardiothorac Surg. 2020 Jan 8;15(1):4. doi: 10.1186/s13019-020-1058-9.

Gehron J, Zirbes J, Bongert M, Schäfer S, Fiebich M, Krombach G, Böning A, Grieshaber P; EMPACS (Exploration of the mixing phenomena during interaction of internal and external circulations) study group (2019)

Development and Validation of a Life-Sized Mock Circulatory Loop of the Human Circulation for Fluid-Mechanical Studies.

ASAIO J. 2019 Nov/Dec;65(8):788-797. doi: 10.1097/MAT.0000000000000880.

Schunkert H, Boening A, von Scheidt M, Lanig C, Gusmini F, de Waha A, Kuna C, Fach A, Grothusen C, Oberhoffer M, Knosalla C, Walther T, Danner BC, Misfeld M, Zeymer U, Wimmer-Greinecker G, Siepe M, Grubitzsch H, Joost A, Schaefer A, Conradi L, Cremer J, Hamm C, Lange R, Radke PW, Schulz R, Laufer G, Grieshaber P, Pader P, Attmann T, Schmoeckel M, Meyer A, Ziegelhöffer T, Hambrecht R, Kastrati A, Sandner SE (2019)

Randomized trial of ticagrelor vs. aspirin in patients after coronary artery bypass grafting: the TiCAB trial.

Eur Heart J. 2019 Aug 1;40(29):2432-2440. doi: 10.1093/eurheartj/ehz185.

Bongert M, Gehron J, Geller M, Böning A, Grieshaber P (2019)

Cannula position and Bernoulli effect contribute to leg malperfusion during extracorporeal life support with femoral arterial cannulation-an in silico simulation study.

Interact Cardiovasc Thorac Surg. 2019 Mar 15. pii: ivz048. doi: 10.1093/icvts/ivz048. [Epub ahead of print]

Bongert M, Gehron J, Geller M, Boening A, Grieshaber P (2019)

In silico study of the dynamic interaction between extracorporeal circulation and native circulation. [pdf-file]

Current Directions in Biomedical Engineering 2018, 4(1), pp. 55-58. Retrieved 4 Jan. 2019, from doi:10.1515/cdbme-2018-0014

Boening A, Assling-Simon L, Heep M, Boengler K, Niemann B, Schipke J, Mühlfeld C, Grieshaber P (2018)

Blood cardioplegia for cardiac surgery in acute myocardial infarction: rat experiments with two widely used solutions.

Interact Cardiovasc Thorac Surg. 2018 Jul 1;27(1):88-94. doi: 10.1093/icvts/ivy011.

Grieshaber P, Schneider T, Oster L, Orhan C, Roth P, Niemann B, Böning A (2018)

Prophylactic intra-aortic balloon counterpulsation before surgical myocardial revascularization in patients with acute myocardial infarction.

Perfusion. 2018 Jul;33(5):390-400. doi: 10.1177/0267659118760384. Epub 2018 Feb 18.

Grieshaber P, Heim N, Herzberg M, Niemann B, Roth P, Boening A (2018)

Active Chest Tube Clearance After Cardiac Surgery Is Associated With Reduced Reexploration Rates.

Ann Thorac Surg. 2018 Jun;105(6):1771-1777. doi: 10.1016/j.athoracsur.2018.01.002. Epub 2018 Jan 31.

Ennker J, Zadeh B, Pons-Kuehnemann J, Niemann B, Grieshaber P, Ennker IC, Boening A (2018)

Stentless Bioprostheses for Aortic Valve Replacement in Octogenarians: The Influence of Coronary Artery Disease.

Thorac Cardiovasc Surg. 2018 Jun;66(4):322-327. doi: 10.1055/s-0037-1604048. Epub 2017 Jul 4.

Boening A, Assling-Simon L, Heep M, Boengler K, Niemann B, Grieshaber P (2018)

Buckberg's blood cardioplegia for protection of adult and senile myocardium in a rat in vitro model of acute myocardial infarction.

Exp Gerontol. 2018 Apr;104:98-104. doi: 10.1016/j.exger.2018.02.003. Epub 2018 Feb 10.

Uhle F, Castrup C, Necaev AM, Grieshaber P, Lichtenstern C, Weigand MA, Böning A (2018)

Inflammation and Its Consequences After Surgical Versus Transcatheter Aortic Valve Replacement.

Artif Organs. 2018 Feb;42(2):E1-E12. doi: 10.1111/aor.13051. Epub 2017 Dec 11.

Grieshaber P, Nink N, Roth P, Elzien M, Böning A, Koshty A (2018)

Endovascular treatment of the ascending aorta using a combined transapical and transfemoral approach.

J Vasc Surg. 2018 Feb;67(2):649-655. doi: 10.1016/j.jvs.2017.10.046. Epub 2017 Nov 20.

Grieshaber P, Oster L, Schneider T, Johnson V, Orhan C, Roth P, Niemann B, Böning A (2018)

Total arterial revascularization in patients with acute myocardial infarction - feasibility and outcomes.

J Cardiothorac Surg. 2018 Jan 5;13(1):2. doi: 10.1186/s13019-017-0691-4.

Grieshaber P, Roth P, Oster L, Schneider TM, Görlach G, Nieman B, Böning A (2017)

Is delayed surgical revascularization in acute myocardial infarction useful or dangerous? New insights into an old problem.

Interact Cardiovasc Thorac Surg. 2017 Nov 1;25(5):772-779. doi: 10.1093/icvts/ivx188.

Grieshaber P, Nef H, Böning A, Niemann B (2017)

Myocardial Ischemia Caused by Subepicardial Hematoma.

Thorac Cardiovasc Surg Rep. 2017 Jan;6(1):e5-e9. doi: 10.1055/s-0037-1601315.

Grieshaber P, Lipp S, Arnold A, Görlach G, Wollbrück M, Roth P, Niemann B, Wilhelm J, Böning A (2016)

Impact of prophylactic administration of Levosimendan on short-term and long-term outcome in high-risk patients with severely reduced left-ventricular ejection fraction undergoing cardiac surgery - a retrospective analysis.

J Cardiothorac Surg. 2016 Dec 1;11(1):162.

Ennker J, Meilwes M, Pons-Kuehnemann J, Niemann B, Grieshaber P, Ennker IC, Boening A (2016)

Freestyle stentless bioprosthesis for aortic valve therapy: 17-year clinical results.

Asian Cardiovasc Thorac Ann. 2016 Nov;24(9):868-874. Epub 2016 Oct 18.

Cabrera-Fuentes HA, Niemann B, Grieshaber P, Wollbrueck M, Gehron J, Preissner KT, Böning A (2015)

RNase1 as a potential mediator of remote ischaemic preconditioning for cardioprotection.

Eur J Cardiothorac Surg. 2015 Nov;48(5):732-7; discussion 737. doi: 10.1093/ejcts/ezu519. Epub 2015 Jan 5.

Grieshaber P, Bakchoul T, Wilhelm J, Wagner A, Wollbrück M, Böning A, Sachs U (2015)

Platelet-activating protamine-heparin-antibodies lead to higher protamine demand in patients undergoing cardiac surgery.

J Thorac Cardiovasc Surg. 2015 Oct;150(4):967-73.e1. doi: 10.1016/j.jtcvs.2015.07.057. Epub 2015 Jul 26.

Grieshaber P, Böning A (2014)

Prophylactic intra-aortic balloon counterpulsation in cardiac surgery: challenges in planning the "right" trial.

Crit Care Med. 2014 Mar;42(3):e246-7. doi: 10.1097/CCM.0000000000000072. No abstract available.

Grieshaber P, Lagrèze WA, Noack C, Boehringer D, Biermann J (2010)

Staining of fluorogold-prelabeled retinal ganglion cells with calcein-AM: A new method for assessing cell vitality.

J Neurosci Methods. 2010 Oct 15;192(2):233–9.