Portrait von apl. Prof. Joachim Füllekrug, PhD
apl. Prof. Joachim Füllekrug, PhD

Forschungsgruppenleiter (AG Prof. Dr. J. Füllekrug: Intracellular transport)
Wiss. Mitarbeiter (Klinik für Gastroenterologie, Infektionen, Vergiftungen)

06221 56-38960
06221 56-5399

The Füllekrug Lab

Ärztlicher / Beruflicher Werdegang


Honorary University title: apl. Professor


Venia legendi for Biochemistry, University of Heidelberg equivalent to Associate Professor

seit 2004

Principal investigator, Internal Medicine IV, University of Heidelberg

1999 – 2003

Research associate, MPI Molecular Cell Biology, Heidelberg/Dresden, Prof. Dr. Kai Simons

1996 – 1998

Postdoctoral research fellow at the European Molecular Biology Laboratory Cell Biology Program, Heidelberg, Dr. T. Nilsson

1992 – 1995

PhD in Biochemistry, University of Göttingen, Prof. Dr. H. D. Söling


Diploma in Chemistry, University of Göttingen

1989 – 1990

Academic exchange, University of Kent at Canterbury, England

Selected publications

Poppelreuther, M., Rudolph, B., Du, C., Grossmann, R., Becker, M., Thiele, C., Ehehalt, R. and J. Füllekrug
The N-terminal region of acyl-CoA synthetase 3 is essential for both the localization on lipid droplets and the function in fatty acid uptake 
J Lipid Res. 53(5), 888-900 (2012)

Digel, M., Staffer, S., Ehehalt, R., Stremmel, W. and J. Füllekrug
FATP4 contributes as an enzyme to the basal and insulin mediated fatty acid uptake of C2C12 muscle cells 
Am J Physiol Endocr Metab. 301, 758-965 (2011)

Digel, M., Ehehalt, R. and J. Füllekrug  
Lipid droplets lighting up: Insights from live microscopy 
FEBS Lett. 584, 2168-2175 (2010)Weiss, K.H., Carbajo, J., Tuma, S., Gotthardt, D., Reichert, J., Ehehalt, R., Stremmel, W. and J. Füllekrug
Copper induced translocation of the Wilson disease protein ATP7B independent of Murr1/ COMMD1 and rab7
Am J Pathol. 173 (6), 1783-94 (2008) 

Spasic, D., T. Raemaekers, K. Dillen, I. Declerck, V. Baert, L. Serneels, J. Füllekrug and W. Annaert
Rer1p competes with APH-1 for binding to Nicastrin and regulates gamma-secretase complex assembly in the early secretory pathway
J Cell Biol. 176, 629-640 (2007)

Milger, K., Herrmann, T., Becker, C., Gotthardt, D., Zickwolf, J., Ehehalt, R., Watkins, P.A., Stremmel, W. and J. Füllekrug
Cellular uptake of fatty acids driven by the ER localized acyl-CoA synthetase FATP4 
J Cell Sci. 119, 4678-88 (2006) 
press release

Meder, D., Shevchenko, A., Simons, K. and J. Füllekrug
Gp135/podocalyxin and NHERF-2 participate in the formation of a pre-apical domain during polarization of MDCK cells
J Cell Biol. 168, 303-313 (2005)

Füllekrug, J. and K. Simons
Lipid Rafts and apical membrane traffic 
Ann NY Acad Sci. 1014, 164-169 (2004)

Schuck, S., Manninen, A., Honsho, M., Füllekrug, J. and K. Simons
Generation of single and double knockdowns in polarized epithelial cells by retrovirus-mediated RNA interference
Proc Natl Acad Sci USA 101, 4912-4917 (2004)

Dahm, T., White, J., Grill, S., Füllekrug, J. and E.H. Stelzer
Quantitative ER-Golgi transport kinetics and protein separation upon Golgi exit revealed by VIP36 dynamics in live cells
Mol Biol Cell 12, 1481-1498 (2001)

Füllekrug, J., Scheiffele, P. and K. Simons
VIP36 localisation to the early secretory pathway
J Cell Sci. 112, 2813-2821 (1999)

Füllekrug, J., Suganuma, T., Tang, B.L., Hong, W., Storrie, B. and T. Nilsson
Localization and recycling of gp27 (hp24γ3): complex formation with other p24 family members
Mol Biol Cell 10, 1939-1955 (1999)

Füllekrug, J., Boehm, J., Röttger, S., Nilsson, T., Mieskes, G. and H.D. Schmitt
Human Rer1 is localized to the Golgi apparatus and complements the deletion of the homologous Rer1 protein of Saccharomyces cerevisiae 
Eur J Cell Biol. 74, 31-40 (1997)