
apl. Prof. Joachim Füllekrug, PhD
Forschungsgruppenleiter
(AG Prof. Dr. J. Füllekrug: Intracellular transport)
Wiss. Mitarbeiter
(Klinik für Gastroenterologie, Infektionen, Vergiftungen)
Ärztlicher / Beruflicher Werdegang
- 2015
Honorary University title: apl. Professor
- 2006
Venia legendi for Biochemistry, University of Heidelberg equivalent to Associate Professor
- seit 2004
Principal investigator, Internal Medicine IV, University of Heidelberg
- 1999 – 2003
Research associate, MPI Molecular Cell Biology, Heidelberg/Dresden, Prof. Dr. Kai Simons
- 1996 – 1998
Postdoctoral research fellow at the European Molecular Biology Laboratory Cell Biology Program, Heidelberg, Dr. T. Nilsson
- 1992 – 1995
PhD in Biochemistry, University of Göttingen, Prof. Dr. H. D. Söling
- 1992
Diploma in Chemistry, University of Göttingen
- 1989 – 1990
Academic exchange, University of Kent at Canterbury, England
Selected publications
Poppelreuther, M., Rudolph, B., Du, C., Grossmann, R., Becker, M., Thiele, C., Ehehalt, R. and J. Füllekrug
The N-terminal region of acyl-CoA synthetase 3 is essential for both the localization on lipid droplets and the function in fatty acid uptake
J Lipid Res. 53(5), 888-900 (2012)Digel, M., Staffer, S., Ehehalt, R., Stremmel, W. and J. Füllekrug
FATP4 contributes as an enzyme to the basal and insulin mediated fatty acid uptake of C2C12 muscle cells
Am J Physiol Endocr Metab. 301, 758-965 (2011)Digel, M., Ehehalt, R. and J. Füllekrug
Lipid droplets lighting up: Insights from live microscopy
FEBS Lett. 584, 2168-2175 (2010)Weiss, K.H., Carbajo, J., Tuma, S., Gotthardt, D., Reichert, J., Ehehalt, R., Stremmel, W. and J. Füllekrug
Copper induced translocation of the Wilson disease protein ATP7B independent of Murr1/ COMMD1 and rab7
Am J Pathol. 173 (6), 1783-94 (2008)Spasic, D., T. Raemaekers, K. Dillen, I. Declerck, V. Baert, L. Serneels, J. Füllekrug and W. Annaert
Rer1p competes with APH-1 for binding to Nicastrin and regulates gamma-secretase complex assembly in the early secretory pathway
J Cell Biol. 176, 629-640 (2007)Milger, K., Herrmann, T., Becker, C., Gotthardt, D., Zickwolf, J., Ehehalt, R., Watkins, P.A., Stremmel, W. and J. Füllekrug
Cellular uptake of fatty acids driven by the ER localized acyl-CoA synthetase FATP4
J Cell Sci. 119, 4678-88 (2006)
press releaseMeder, D., Shevchenko, A., Simons, K. and J. Füllekrug
Gp135/podocalyxin and NHERF-2 participate in the formation of a pre-apical domain during polarization of MDCK cells
J Cell Biol. 168, 303-313 (2005)Füllekrug, J. and K. Simons
Lipid Rafts and apical membrane traffic
Ann NY Acad Sci. 1014, 164-169 (2004)Schuck, S., Manninen, A., Honsho, M., Füllekrug, J. and K. Simons
Generation of single and double knockdowns in polarized epithelial cells by retrovirus-mediated RNA interference
Proc Natl Acad Sci USA 101, 4912-4917 (2004)Dahm, T., White, J., Grill, S., Füllekrug, J. and E.H. Stelzer
Quantitative ER-Golgi transport kinetics and protein separation upon Golgi exit revealed by VIP36 dynamics in live cells
Mol Biol Cell 12, 1481-1498 (2001)Füllekrug, J., Scheiffele, P. and K. Simons
VIP36 localisation to the early secretory pathway
J Cell Sci. 112, 2813-2821 (1999)Füllekrug, J., Suganuma, T., Tang, B.L., Hong, W., Storrie, B. and T. Nilsson
Localization and recycling of gp27 (hp24γ3): complex formation with other p24 family members
Mol Biol Cell 10, 1939-1955 (1999)Füllekrug, J., Boehm, J., Röttger, S., Nilsson, T., Mieskes, G. and H.D. Schmitt
Human Rer1 is localized to the Golgi apparatus and complements the deletion of the homologous Rer1 protein of Saccharomyces cerevisiae
Eur J Cell Biol. 74, 31-40 (1997)