Personen

Prof. Dr. med. Peter Sinn

Arbeitsgruppenleiter (AG Sinn Mammakarzinom)
Oberarzt (Allgemeine Pathologie und Pathologische Anatomie)


AG Sinn Mammakarzinom

Ärztlicher / Beruflicher Werdegang

1976 – 1982

Medical Schools, Universities of Erlangen and TU Munich, Germany

seit 1982

MD-Thesis (magna cum laude), Univ. of Erlangen

seit 1982

Licensure (Approbation) in Medicine, TU Munich

seit 1993

Board Certification in Pathology

seit 1999

PhD Degree (Habilitation)

Wissenschaftlicher Werdegang

1983 – 1986

Resident, Dept. of Pathology Univ. of Marburg

1986 – 1987

Postdoctoral Research Fellowship (DFG) Dept. of Pathology

1987 – 1992

Resident, Dept. of Pathology University of Heidelberg

seit 1993

Consultant (Oberarzt), Dept. of Pathology University of Heidelberg

seit 1999

Head, Division of Gynecopathology, Univ. Hospital, Heidelberg

seit 2005

Associate Professor of Pathology (apl. Prof.) Univ. of Heidelberg

Auszeichnungen

seit 2002

Posterpreis der Dt. Ges. f. Senologie (DGS)

seit 2011

Posterpreis der International Society for the Study of Vulvovaginal Disease (ISSVD)

seit 2018

Posterpreis der Dt. Ges. f. Senologie (DGS)

Mitgliedschaften

Member, German Society of Pathology (DGP)
Member, European Society of Pathology (ESP)
Member, International Academy of Pathology (IAP), German Division
Member, Arbeitsgemeinschaft für Gynäkologische Onkologie (AGO)
Member, German Society of Senology (DGS)
Member, German Cancer Society (DKG)
Fellow, International Society for the Study of Vulvovaginal Disease (ISSVD)

Ämter und Funktionen

Member, AGO Organkommission Mamma
Member, Interdisciplinary S3 guideline committee breast cancer
Member, Educational Committee of the IAP, German Division

Fields of Interest

Molecular and translational pathology of the breast and female genital tract. Digital pathology in education and research

Selected publications (2016 – 2020)

  1. Gutjahr E, Streng A, Aulmann S, Flechtenmacher C, Toberer F, Heil J, Böcker W, Sinn P. Pathologie der Mamillenregion : Teil II: Tumoren, tumorartige Läsionen und Überschussbildungen. Der Pathologe. 4 ed. Springer Medizin; 2020 May 26;51(10):e203–8. PMID: 32458047
  2. Streng A, Gutjahr E, Aulmann S, Flechtenmacher C, Toberer F, Heil J, Böcker W, Sinn P. Pathologie der Mamillenregion : I. Morbus Paget der Mamille, Varianten und Differenzialdiagnosen. Der Pathologe. 3rd ed. 2020 May 13;29(4):14–399. PMID: 32405655
  3. Heil J, Pfob A, Kuerer HM. De-escalation towards omission is the tipping point of individualizing breast cancer surgery. Eur J Surg Oncol. 2020 Mar 19. PMID: 32241595
  4. Golatta M, Vrancken Peeters MJ. Eliminating the breast cancer surgery paradigm after neoadjuvant systemic therapy: current evidence and future challenges. Ann Oncol. 2020 Jan;31(1):61–71. PMID: 31912797
  5. Klebe M, Fremd C, Kriegsmann M, Kriegsmann K, Albrecht T, Thewes V, Kirchner M, Charoentong P, Volk N, Haag J, Wirtz R, Oskarsson T, Schulz A, Heil J, Schneeweiss A, Winter H, Sinn P. Frequent Molecular Subtype Switching and Gene Expression Alterations in Lung and Pleural Metastasis From Luminal A-Type Breast Cancer. JCO Precision Oncology. 2020;4:848–859. PMCID: PMC7446514
  6. Heil J, Pfob A, Sinn P, Rauch G, Bach P, Thomas B, Schaefgen B, Kuemmel S, Reimer T, Hahn M, Thill M, Blohmer J-U, Hackmann J, Malter W, Bekes I, Friedrichs K, Wojcinski S, Joos S, Paepke S, Ditsch N, Rody A, Große R, van Mackelenbergh M, Reinisch M, Karsten M, Golatta M. Diagnosing Pathologic Complete Response in the Breast After Neoadjuvant Systemic Treatment of Breast Cancer Patients by Minimal Invasive Biopsy. Ann Surg. 2020;Publish Ahead of Print.
  7. Rüschoff J, Lebeau A, Sinn P, Schildhaus H-U, Decker T, Ammann J, Künzel C, Koch W, Untch M. Statistical modelling of HER2-positivity in breast cancer: Final analyses from two large, multicentre, non-interventional studies in Germany. Breast. 2019 Dec 18;49:246–253. PMID: 31918324
  8. Funk A, Heil J, Harcos A, Gomez C, Stieber A, Junkermann H, Hennigs A, Rauch G, Sinn HP, Riedel F, Schäfgen B, Hug S, Maier A, Blumenstein M, Domschke C, Schott S, Wallwiener M, Rom J, Schütz F, Sohn C, Golatta M. Efficacy of intraoperative specimen radiography as margin assessment tool in breast conserving surgery. Breast Cancer Res Treat. 7 ed. 2019 Oct 25;347(16):1233. PMID: 31654190
  9. Glaeser A, Sinn P, Garcia-Etienne C, Riedel F, Hug S, Schaefgen B, Golatta M, Hennigs A, Feisst M, Sohn C, Heil J. Heterogeneous Responses of Axillary Lymph Node Metastases to Neoadjuvant Chemotherapy are Common and Depend on Breast Cancer Subtype. Ann Surg Oncol. Springer International Publishing; 2019 Oct 11;116(12):2884–9. PMID: 31605339
  10. Varga Z, Sinn P, Seidman A. Author's reply to: Comparing the performance of gene expression assays in breast cancer. Int J Cancer. 2019 Aug 15;145(4):1163–1164. PMID: 30895601
  11. Varga Z, Sinn P, Seidman A. Summary of head-to-head comparisons of patient risk classifications by the 21-gene Recurrence Score® (RS) assay and other genomic assays for early breast cancer. Int J Cancer. 2019 Aug 15;145(4):882–893. PMID: 30653259
  12. Ditsch N, Untch M, Thill M, Müller V, Janni W, Albert U-S, Bauerfeind I, Blohmer J, Budach W, Dall P, Diel I, Fasching PA, Fehm T, Friedrich M, Gerber B, Hanf V, Harbeck N, Huober J, Jackisch C, Kolberg-Liedtke C, Kreipe H-H, Krug D, Kühn T, Kümmel S, Loibl S, Lüftner D, Lux MP, Maass N, Möbus V, Müller-Schimpfle M, Mundhenke C, Nitz U, Rhiem K, Rody A, Schmidt M, Schneeweiss A, Schütz F, Sinn P, Solbach C, Solomayer E-F, Stickeler E, Thomssen C, Wenz F, Witzel I, Wöckel A. AGO Recommendations for the Diagnosis and Treatment of Patients with Early Breast Cancer: Update 2019. Breast Care. 2019 Aug;14(4):224–245. PMCID: PMC6751475
  13. Thill M, Jackisch C, Janni W, Müller V, Albert U-S, Bauerfeind I, Blohmer J, Budach W, Dall P, Diel I, Fasching PA, Fehm T, Friedrich M, Gerber B, Hanf V, Harbeck N, Huober J, Kolberg-Liedtke C, Kreipe H-H, Krug D, Kühn T, Kümmel S, Loibl S, Lüftner D, Lux MP, Maass N, Möbus V, Müller-Schimpfle M, Mundhenke C, Nitz U, Rhiem K, Rody A, Schmidt M, Schneeweiss A, Schütz F, Sinn P, Solbach C, Solomayer E-F, Stickeler E, Thomssen C, Untch M, Wenz F, Witzel I, Wöckel A, Ditsch N. AGO Recommendations for the Diagnosis and Treatment of Patients with Locally Advanced and Metastatic Breast Cancer: Update 2019. Breast Care. 2019 Aug;14(4):247–255. PMCID: PMC6751428
  14. Kriegsmann M, Gomez C, Heil J, Schäfgen B, Gutjahr E, Kommoss FKF, Kriegsmann K, Flechtenmacher C, Goeppert B, Sinn P. IgG4-related sclerosing mastitis in a 49-year-old patient with multiple, tumor-like nodules-Diagnostic accuracy of core needle biopsy. Breast Journal. 2019 Jul 6;366(6):539–1253. PMID: 31280490
  15. Stefanovic S, Deutsch TM, Wirtz R, Hartkopf A, Sinn P, Schuetz F, Sohn C, Bohlmann MK, Sütterlin M, Schneeweiss A, Wallwiener M. Molecular Subtype Conversion between Primary and Metastatic Breast Cancer Corresponding to the Dynamics of Apoptotic and Intact Circulating Tumor Cells. Cancers (Basel). 2019 Mar 11;11(3). PMCID: PMC6468370
  16. Fremd C, Hlevnjak M, Zapatka M, Zoernig I, Halama N, Fejzibegovic N, Thewes V, Lichter P, Schirmacher P, Kloor M, Marme F, Schütz F, Kosaloglu Z, Sinn P, Jäger D, Schneeweiss A. Mismatch Repair Deficiency Drives Durable Complete Remission by Targeting Programmed Death Receptor 1 in a Metastatic Luminal Breast Cancer Patient. Breast Care. 2019 Mar;14(1):53–59. PMCID: PMC6465703
  17. Lebeau A, Denkert C, Sinn P, Schmidt M, Wöckel A. Update der S3-Leitlinie Mammakarzinom : Was gibt es Neues für Pathologen? Der Pathologe. Springer Medizin; 2019 Mar;40(2):185–198. PMID: 30847505
  18. Vogt PH, Besikoglu B, Bettendorf M, Frank-Herrmann P, Zimmer J, Bender U, Knauer-Fischer S, Choukair D, Sinn P, Lau Y-FC, Heidemann PH, Strowitzki T. Gonadoblastoma Y locus genes expressed in germ cells of individuals with dysgenetic gonads and a Y chromosome in their karyotypes include DDX3Y and TSPY. Hum Reprod. 2019 Feb 12;34(4):770–779. PMID: 30753444
  19. Jauch SF, Riethdorf S, Sprick MR, Schütz F, Schönfisch B, Brucker SY, Deutsch TM, Nees J, Saini M, Becker LM, Burwinkel B, Sinn P, Marme F, Pantel K, Jäger D, Sohn C, Trumpp A, Wallwiener M, Schneeweiss A. Sustained prognostic impact of circulating tumor cell status and kinetics upon further progression of metastatic breast cancer. Breast Cancer Res Treat. 2019 Jan;173(1):155–165. PMID: 30276763
  20. Thoeni C, Holzer K, Leichsenring J, Porcel C, Straub BK, Sinn HP, Elsaesser M, Volckmar AL, Schirmacher P, Waldherr R, Lasitschka F. Renal Tubular Dysgenesis in a Case of Fetus Acardius Amorphus. Case Reports in Pathology. 2019;2019:5416936. PMCID: PMC6875321
  21. Heil J, Richter H, Golatta M, Sinn P. Vacuum-Assisted Biopsy to Diagnose a Pathological Complete Response in Breast Cancer Patients After Neoadjuvant Systemic Therapy. Ann Surg. 2018 Dec;268(6):e60–e61. PMID: 29064903
  22. Heil J, Sinn P, Richter H, Pfob A, Schaefgen B, Hennigs A, Riedel F, Thomas B, Thill M, Hahn M, Blohmer J-U, Kuemmel S, Karsten MM, Reinisch M, Hackmann J, Reimer T, Rauch G, Golatta M. RESPONDER - diagnosis of pathological complete response by vacuum-assisted biopsy after neoadjuvant chemotherapy in breast Cancer - a multicenter, confirmative, one-armed, intra-individually-controlled, open, diagnostic trial. BMC Cancer. BioMed Central; 2018 Aug 25;18(1):851. PMCID: PMC6109284
  23. Abubakar M, Chang-Claude J, Ali HR, Chatterjee N, Coulson P, Daley F, Blows F, Benitez J, Milne RL, Brenner H, Stegmaier C, Mannermaa A, Rudolph A, Sinn P, Couch FJ, Devilee P, Tollenaar RAEM, Seynaeve C, Figueroa J, Lissowska J, Hewitt S, Hooning MJ, Hollestelle A, Foekens R, Koppert LB, investigators K, Bolla MK, Wang Q, Jones ME, Schoemaker MJ, Keeman R, Easton DF, Swerdlow AJ, Sherman ME, Schmidt MK, Pharoah PD, García-Closas M. Etiology of hormone receptor positive breast cancer differs by levels of histologic grade and proliferation. Int J Cancer. John Wiley & Sons, Ltd; 2018 Aug 15;143(4):746–757. PMCID: PMC6041155
  24. Polycarpou-Schwarz M, Groß M, Mestdagh P, Schott J, Grund SE, Hildenbrand C, Rom J, Aulmann S, Sinn P, Vandesompele J, Diederichs S. The cancer-associated microprotein CASIMO1 controls cell proliferation and interacts with squalene epoxidase modulating lipid droplet formation. Oncogene. Nature Publishing Group; 2018 Aug;37(34):4750–4768. PMID: 29765154
  25. Shirahata M, Ono T, Stichel D, Schrimpf D, Reuss DE, Sahm F, Koelsche C, Wefers A, Reinhardt A, Huang K, Sievers P, Shimizu H, Nanjo H, Kobayashi Y, Miyake Y, Suzuki T, Adachi J-I, Mishima K, Sasaki A, Nishikawa R, Bewerunge-Hudler M, Ryzhova M, Absalyamova O, Golanov A, Sinn P, Platten M, Jungk C, Winkler F, Wick A, Hänggi D, Unterberg A, Pfister SM, Jones DTW, van den Bent M, Hegi M, French P, Baumert BG, Stupp R, Gorlia T, Weller M, Capper D, Korshunov A, Herold-Mende C, Wick W, Louis DN, Deimling von A. Novel, improved grading system(s) for IDH-mutant astrocytic gliomas. Acta Neuropathol. 4 ed. Springer Berlin Heidelberg; 2018 Jul;136(1):153–166. PMID: 29687258
  26. Thill M, Liedtke C, Müller V, Janni W, Schmidt M, AGO Breast Committee. AGO Recommendations for the Diagnosis and Treatment of Patients with Advanced and Metastatic Breast Cancer: Update 2018. Breast Care. 2018 Jul;13(3):209–215. PMCID: PMC6062660
  27. Riedel F, Sellner L, Harcos A, Sinn H, Hennigs A, Golatta M, Heil J, Mayer L. Aggressives B-Zell-Non-Hodgkin-Lymphom der Mamma bei einer 77-jährigen Patientin. TumorDiagn u Ther. © Georg Thieme Verlag KG; 2018 May 14;39(04):239–242.
  28. Pfitzner BM, Lederer B, Lindner J, Solbach C, Engels K, Rezai M, Dohnal K, Tesch H, Hansmann ML, Salat C, Beer M, Schneeweiss A, Sinn P, Bánkfalvi A, Darb-Esfahani S, Minckwitz von G, Sinn BV, Kronenwett R, Weber K, Denkert C, Loibl S. Clinical relevance and concordance of HER2 status in local and central testing-an analysis of 1581 HER2-positive breast carcinomas over 12 years. Mod Pathol. 2018 Apr;31(4):607–615. PMID: 29271415
  29. Block MS, Vierkant RA, Rambau PF, Winham SJ, Wagner P, Traficante N, Tołoczko A, Tiezzi DG, Taran F-A, Sinn P, Sieh W, Sharma R, Rothstein JH, Ramón y Cajal T, Paz-Ares L, Oszurek O, Orsulic S, Ness RB, Nelson G, Modugno F, Menkiszak J, McGuire V, McCauley BM, Mack M, Lubinski J, Longacre TA, Li Z, Lester J, Kennedy CJ, Kalli KR, Jung AY, Johnatty SE, Jimenez-Linan M, Jensen A, Intermaggio MP, Hung J, Herpel E, Hernandez BY, Hartkopf AD, Harnett PR, Ghatage P, García-Bueno JM, Gao B, Fereday S, Eilber U, Edwards RP, de Sousa CB, de Andrade JM, Chudecka-Głaz A, Chenevix-Trench G, Cazorla A, Brucker SY, Australian Ovarian Cancer Study Group, Alsop J, Whittemore AS, Steed H, Staebler A, Moysich KB, Menon U, Koziak JM, Kommoss S, Kjaer SK, Kelemen LE, Karlan BY, Huntsman DG, Hogdall E, Gronwald J, Goodman MT, Gilks B, García MJ, Fasching PA, de Fazio A, Deen S, Chang-Claude J, Candido Dos Reis FJ, Campbell IG, Brenton JD, Bowtell DD, Benitez J, Pharoah PDP, Köbel M, Ramus SJ, Goode EL. MyD88 and TLR4 Expression in Epithelial Ovarian Cancer. 2018 Mar;93(3):307–320. PMCID: PMC5870793
  30. Denkert C, Minckwitz von G, Darb-Esfahani S, Lederer B, Heppner BI, Weber KE, Budczies J, Huober J, Klauschen F, Furlanetto J, Schmitt WD, Blohmer J-U, Karn T, Pfitzner BM, Kümmel S, Engels K, Schneeweiss A, Hartmann A, Noske A, Fasching PA, Jackisch C, van Mackelenbergh M, Sinn P, Schem C, Hanusch C, Untch M, Loibl S. Tumour-infiltrating lymphocytes and prognosis in different subtypes of breast cancer: a pooled analysis of 3771 patients treated with neoadjuvant therapy. Lancet Oncol. 2018 Jan;19(1):40–50. PMID: 29233559
  31. Bartosova M, Schaefer B, Bermejo JL, Tarantino S, Lasitschka F, Macher-Goeppinger S, Sinn P, Warady BA, Zaloszyc A, Parapatics K, Májek P, Bennett KL, Oh J, Aufricht C, Schaefer F, Kratochwill K, Schmitt CP. Complement Activation in Peritoneal Dialysis-Induced Arteriolopathy. J Am Soc Nephrol. 2018 Jan;29(1):268–282. PMCID: PMC5748916
  32. Jauch SF, Riethdorf S, Sprick MR, Schutz F, Schönfisch B, Brucker SY, Deutsch TM, Nees J, Saini M, Becker LM, Burwinkel B, Sinn P, Marme F, Pantel K, Jäger D, Sohn C, Trumpp A, Wallwiener M, Schneeweiss A. Zur prognostischen Relevanz des CTC-Status bei Progress des metastasierten Mammakarzinoms. Senologie. 2018. p. 136–137.
  33. Heublein S, Braun E, Schulz A, Fremd C, Kirchner M, Jäger D, Sohn C, Sinn P, Schneeweiss A. Molekulare Prädiktoren zur Abschätzung des Therapieansprechens von Patientinnen mit frühem triple-negativen Mammakarzinom. Geburtsh Frauenheilkd. 2018. p. FV30.
  34. Ovarian Tumor Tissue Analysis (OTTA) Consortium, Goode EL, Block MS, Kalli KR, Vierkant RA, Chen W, Fogarty ZC, Gentry-Maharaj A, Tołoczko A, Hein A, Bouligny AL, Jensen A, Osorio A, Hartkopf A, Ryan A, Chudecka-Głaz A, Magliocco AM, Hartmann A, Jung AY, Gao B, Hernandez BY, Fridley BL, McCauley BM, Kennedy CJ, Wang C, Karpinskyj C, de Sousa CB, Tiezzi DG, Wachter DL, Herpel E, Taran F-A, Modugno F, Nelson G, Lubinski J, Menkiszak J, Alsop J, Lester J, García-Donas J, Nation J, Hung J, Palacios J, Rothstein JH, Kelley JL, de Andrade JM, Robles-Díaz L, Intermaggio MP, Widschwendter M, Beckmann MW, Ruebner M, Jimenez-Linan M, Singh N, Oszurek O, Harnett PR, Rambau PF, Sinn P, Wagner P, Ghatage P, Sharma R, Edwards RP, Ness RB, Orsulic S, Brucker SY, Johnatty SE, Longacre TA, Ursula E, McGuire V, Sieh W, Natanzon Y, Li Z, Whittemore AS, Anna D, Staebler A, Karlan BY, Gilks B, Bowtell DD, Hogdall E, Candido Dos Reis FJ, Steed H, Campbell IG, Gronwald J, Benitez J, Koziak JM, Chang-Claude J, Moysich KB, Kelemen LE, Cook LS, Goodman MT, García MJ, Fasching PA, Kommoss S, Deen S, Kjaer SK, Menon U, Brenton JD, Pharoah PD, Chenevix-Trench G, Huntsman DG, Winham SJ, Köbel M, Ramus SJ. Dose-Response Association of CD8+ Tumor-Infiltrating Lymphocytes and Survival Time in High-Grade Serous Ovarian Cancer. JAMA Oncol. 2017 Dec 1;3(12):e173290. PMCID: PMC5744673
  35. Sinn P, Schneeweiss A, Endris V, Penzel R, Schirmacher P, Stenzinger A. Intrinsic subtypes and risk scores in ER+/HER2-Breast Cancer: a comparison of Prosigna and OncotypeDX risk categories with Ki67. Der Pathologe. 2017. p. 540.
  36. Varga Z, Sinn P, McCullough D, Lau A, Stöppler MC, Baehner FL, Chao C, Seidman A. 187PSummary of head-to-head comparisons of patient (pt) risk classifications by the 21-gene recurrence score (RS) assay and other genomic assays for early breast cancer (EBC). Ann Oncol [Internet]. Oxford University Press; 2017 Sep 1;28(suppl_5):57. Available from: academic.oup.com/annonc/article/doi/10.1093/annonc/mdx362.037/4108354
  37. Stefanovic S, Wirtz R, Deutsch TM, Hartkopf A, Sinn P, Varga Z, Sobottka B, Sotiris L, Taran F-A, Domschke C, Hennigs A, Brucker SY, Sohn C, Schuetz F, Schneeweiss A, Wallwiener M. Tumor biomarker conversion between primary and metastatic breast cancer: mRNA assessment and its concordance with immunohistochemistry. Oncotarget. 2017 Aug 1;8(31):51416–51428. PMCID: PMC5584258
  38. Thewes V, Simon R, Hlevnjak M, Schlotter M, Schroeter P, Schmidt K, Wu Y, Anzeneder T, Wang W, Windisch P, Kirchgäßner M, Melling N, Kneisel N, Büttner R, Deuschle U, Sinn HP, Schneeweiss A, Heck S, Kaulfuss S, Hess-Stumpp H, Okun JG, Sauter G, Lykkesfeldt AE, Zapatka M, Radlwimmer B, Lichter P, Tönjes M. The branched-chain amino acid transaminase 1 sustains growth of antiestrogen-resistant and ERα-negative breast cancer. Oncogene. Nature Publishing Group; 2017 Jul 1;36(29):4124–4134.
  39. Untch M, Huober J, Jackisch C, Schneeweiss A, Brucker SY, Dall P, Denkert C, Fasching PA, Fehm T, Gerber B, Janni W, Kühn T, Lüftner D, Möbus V, Müller V, Sinn P, Thill M, Thomssen C, Harbeck N, Liedtke C. Erstbehandlung von Patientinnen mit primärem Mammakarzinom: Evidenz, Kontroversen, Konsens. Geburtsh Frauenheilkd. 2017 Jun;77(6):633–644. PMCID: PMC5489401
  40. Untch M, Huober J, Jackisch C, Schneeweiss A, Brucker SY, Dall P, Denkert C, Fasching PA, Fehm T, Gerber B, Janni W, Kühn T, Lüftner D, Möbus V, Müller V, Rody A, Sinn P, Thill M, Thomssen C, Harbeck N, Liedtke C. Initial Treatment of Patients with Primary Breast Cancer: Evidence, Controversies, Consensus: Spectrum of Opinion of German Specialists at the 15th International St. Gallen Breast Cancer Conference (Vienna 2017). Geburtsh Frauenheilkd. 2017 Jun;77(6):633–644. PMCID: PMC5489401
  41. Varga Z, Lebeau A, Bu H, Hartmann A, Penault-Llorca F, Guerini-Rocco E, Schraml P, Symmans F, Stoehr R, Teng X, Turzynski A, Wasielewski von R, Gürtler C, Laible M, Schlombs K, Joensuu H, Keller T, Sinn P, Sahin U, Bartlett J, Viale G. An international reproducibility study validating quantitative determination of ERBB2, ESR1, PGR, and MKI67 mRNA in breast cancer using MammaTyper®. Breast Cancer Res. 7 ed. BioMed Central; 2017 May 11;19(1):55. PMCID: PMC5426065
  42. Riedel F, Hennigs A, Marme F, Sinn P, Lindel K, Gondos A, Smetanay K, Golatta M, Sohn C, Schutz F, Heil J, Schneeweiss A. Veränderungen in der Anwendung und beim Outcome von Chemotherapie beim frühen Mammakarzinom in der letzten Dekade (2003 – 2014). Senologie. 2017 May 9;14(02):A1–A53.
  43. Pfarr N, Penzel R, Endris V, Lier C, Flechtenmacher C, Volckmar A-L, Kirchner M, Budczies J, Leichsenring J, Herpel E, Noske A, Weichert W, Schneeweiss A, Schirmacher P, Sinn P, Stenzinger A. Targeted next-generation sequencing enables reliable detection of HER2 (ERBB2) status in breast cancer and provides ancillary information of clinical relevance. Genes Chromosomes Cancer. 2017 Apr;56(4):255–265. PMID: 27792260
  44. Sinn P, Schneeweiss A, Endris V, Penzel R, Schirmacher P, Kirchner M, Stenzinger A. Intrinsic subtypes and risk scores in ER+/HER2-Breast Cancer: a comparison of Prosigna and OncotypeDX risk categories with Ki67. Breast. Elsevier; 2017. p. S105.
  45. Sinn P, Schneeweiss A, Keller M, Schlombs K, Laible M, Seitz J, Lakis S, Veltrup E, Altevogt P, Eidt S, Wirtz RM, Marme F. Comparison of immunohistochemistry with PCR for assessment of ER, PR, and Ki-67 and prediction of pathological complete response in breast cancer. BMC Cancer. 2017 Feb 13;17(1):124. PMCID: PMC5307758
  46. Rüschoff J, Lebeau A, Kreipe H, Sinn P, Gerharz CD, Koch W, Morris S, Ammann J, Untch M, Nicht-interventionelle Untersuchung (NIU) HER2 Study Group. Assessing HER2 testing quality in breast cancer: variables that influence HER2 positivity rate from a large, multicenter, observational study in Germany. Mod Pathol. Nature Publishing Group; 2017 Feb;30(2):217–226. PMID: 27767099
  47. Blohmer J, Sinn P. 243. Stellungnahme der Deutschen Gesellschaft für Gynäkologie und Geburtshilfe (DGGG) zum Aufruf des Wissenschaftlichen Komitees für Gesundheit, Umwelt und neue Risiken der Europäischen Kommission (SCHEER) zur Sicherheit von PIP-Silikon-Brustimplantaten sowie auch den Zusammenhang zwischen Brustimplantaten und ALCL. Geburtsh Frauenheilkd. 2017;(77):617–619.
  48. Rabe T, Schweppe KW et al. Adenomyosis uteri. J Reproduktionsmed Endokrinol. 2017;14(5):211–218.
  49. Hennigs A, Riedel F, Marme F, Sinn P, Lindel K, Gondos A, Smetanay K, Golatta M, Sohn C, Schuetz F, Heil J, Schneeweiss A. Changes in chemotherapy usage and outcome of early breast cancer patients in the last decade. Breast Cancer Res Treat. 4 ed. Springer US; 2016 Dec;160(3):491–499. PMCID: PMC5090013
  50. Heil J, Schaefgen B, Sinn P, Richter H, Harcos A, Gomez C, Stieber A, Hennigs A, Rauch G, Schuetz F, Sohn C, Schneeweiss A, Golatta M. Can a pathological complete response of breast cancer after neoadjuvant chemotherapy be diagnosed by minimal invasive biopsy? Eur J Cancer. Elsevier; 2016 Nov 4;69:142–150. PMID: 27821317
  51. Rippinger N, Elsässer M, Sinn P, Sohn C, Fluhr H. Lean Umbilical Cord - a Case Report. Geburtsh Frauenheilkd. 2016 Nov;76(11):1186–1188. PMCID: PMC5123883
  52. Abubakar M, Orr N, Daley F, Coulson P, Ali HR, Blows F, Benitez J, Milne R, Brenner H, Stegmaier C, Mannermaa A, Chang-Claude J, Rudolph A, Sinn P, Couch FJ, Devilee P, Tollenaar RAEM, Seynaeve C, Figueroa J, Sherman ME, Lissowska J, Hewitt S, Eccles D, Hooning MJ, Hollestelle A, Martens JWM, van Deurzen CHM, investigators K, Bolla MK, Wang Q, Jones M, Schoemaker M, Wesseling J, van Leeuwen FE, van t Veer L, Easton D, Swerdlow AJ, Dowsett M, Pharoah PD, Schmidt MK, García-Closas M. Prognostic value of automated KI67 scoring in breast cancer: a centralised evaluation of 8088 patients from 10 study groups. Breast Cancer Res. BioMed Central; 2016 Oct 18;18(1):104. PMCID: PMC5070183
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